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Volumn 16, Issue 7, 2015, Pages 14511-14525

MiR-21 protected cardiomyocytes against doxorubicin-induced apoptosis by targeting BTG2

Author keywords

B cell translocation gene 2 (BTG 2); Cardiotoxicity; Doxorubicin (DOX); MicroRNA 21 (miR 21)

Indexed keywords

DOXORUBICIN; LACTATE DEHYDROGENASE; MICRORNA 21; ANTINEOPLASTIC AGENT; BTG2 PROTEIN, RAT; IMMEDIATE EARLY PROTEIN; MICRORNA; MIRN21 MICRORNA, RAT; TUMOR SUPPRESSOR PROTEIN;

EID: 84933556434     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms160714511     Document Type: Article
Times cited : (86)

References (32)
  • 1
    • 2642566088 scopus 로고    scopus 로고
    • Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
    • Minotti, G.; Menna, P.; Salvatorelli, E.; Cairo, G.; Gianni, L. Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol. Rev. 2004, 56, 185–229
    • (2004) Pharmacol. Rev , vol.56 , pp. 185-229
    • Minotti, G.1    Menna, P.2    Salvatorelli, E.3    Cairo, G.4    Gianni, L.5
  • 2
    • 0015849162 scopus 로고
    • A clinicopathologic analysis of adriamycin cardiotoxicity
    • Lefrak, E.A.; Pitha, J.; Rosenheim, S.; Gottlieb, J.A. A clinicopathologic analysis of adriamycin cardiotoxicity. Cancer 1973, 32, 302–314
    • (1973) Cancer , vol.32 , pp. 302-314
    • Lefrak, E.A.1    Pitha, J.2    Rosenheim, S.3    Gottlieb, J.A.4
  • 3
  • 4
    • 84865060042 scopus 로고    scopus 로고
    • Breast cancer treatment and adverse cardiac events: What are the molecular mechanisms?
    • Roca-Alonso, L.; Pellegrino, L.; Castellano, L.; Stebbing, J. Breast cancer treatment and adverse cardiac events: What are the molecular mechanisms? Cardiology 2012, 122, 253–259
    • (2012) Cardiology , vol.122 , pp. 253-259
    • Roca-Alonso, L.1    Pellegrino, L.2    Castellano, L.3    Stebbing, J.4
  • 5
    • 0034255404 scopus 로고    scopus 로고
    • Fas-mediated apoptosis in adriamycin-induced cardiomyopathy in rats: In vivo study
    • Nakamura, T.; Ueda, Y.; Juan, Y.; Katsuda, S.; Takahashi, H.; Koh, E. Fas-mediated apoptosis in adriamycin-induced cardiomyopathy in rats: In vivo study. Circulation 2000, 102, 572–578
    • (2000) Circulation , vol.102 , pp. 572-578
    • Nakamura, T.1    Ueda, Y.2    Juan, Y.3    Katsuda, S.4    Takahashi, H.5    Koh, E.6
  • 6
    • 70450260555 scopus 로고    scopus 로고
    • Cardiomyocyte death in doxorubicin-induced cardiotoxicity
    • Zhang, Y.W.; Shi, J.; Li, Y.J.; Wei, L. Cardiomyocyte death in doxorubicin-induced cardiotoxicity. Arch. Immunol. Ther. Exp. 2009, 57, 435–445
    • (2009) Arch. Immunol. Ther. Exp , vol.57 , pp. 435-445
    • Zhang, Y.W.1    Shi, J.2    Li, Y.J.3    Wei, L.4
  • 7
    • 80455123713 scopus 로고    scopus 로고
    • New role of microRNA: Carcinogenesis and clinical application in cancer
    • Zhao, L.; Chen, X.; Cao, Y. New role of microRNA: Carcinogenesis and clinical application in cancer. Acta Biochim. Biophys. Sin. 2011, 43, 831–839
    • (2011) Acta Biochim. Biophys. Sin , vol.43 , pp. 831-839
    • Zhao, L.1    Chen, X.2    Cao, Y.3
  • 8
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros, V. The functions of animal microRNAs. Nature 2004, 431, 350–355
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 9
    • 52449116560 scopus 로고    scopus 로고
    • MicroRNAs: Novel regulators in cardiac development and disease
    • Thum, T.; Catalucci, D.; Bauersachs, J. MicroRNAs: Novel regulators in cardiac development and disease. Cardiovasc. Res. 2008, 79, 562–570
    • (2008) Cardiovasc. Res , vol.79 , pp. 562-570
    • Thum, T.1    Catalucci, D.2    Bauersachs, J.3
  • 10
    • 77956921020 scopus 로고    scopus 로고
    • MicroRNA-21: From cancer to cardiovascular disease
    • Jazbutyte, V.; Thum, T. MicroRNA-21: From cancer to cardiovascular disease. Curr. Drug Targets 2010, 11, 926–935
    • (2010) Curr. Drug Targets , vol.11 , pp. 926-935
    • Jazbutyte, V.1    Thum, T.2
  • 12
    • 62349141343 scopus 로고    scopus 로고
    • MicroRNA expression in response to murine myocardial infarction: MiR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue
    • Roy, S.; Khanna, S.; Hussain, S.R.; Biswas, S.; Azad, A.; Rink, C.; Gnyawali, S.; Shilo, S.; Nuovo, G.J.; Sen, C.K. MicroRNA expression in response to murine myocardial infarction: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue. Cardiovasc. Res. 2009, 82, 21–29
    • (2009) Cardiovasc. Res , vol.82 , pp. 21-29
    • Roy, S.1    Khanna, S.2    Hussain, S.R.3    Biswas, S.4    Azad, A.5    Rink, C.6    Gnyawali, S.7    Shilo, S.8    Nuovo, G.J.9    Sen, C.K.10
  • 13
    • 70350353082 scopus 로고    scopus 로고
    • MicroRNA expression signature and the role of microRNA-21 in the early phase of acute myocardial infarction
    • Dong, S.; Cheng, Y.; Yang, J.; Li, J.; Liu, X.; Wang, X.; Wang, D.; Krall, T.J.; Delphin, E.S.; Zhang, C. MicroRNA expression signature and the role of microRNA-21 in the early phase of acute myocardial infarction. J. Biol. Chem. 2009, 284, 29514–29525
    • (2009) J. Biol. Chem , vol.284 , pp. 29514-29525
    • Dong, S.1    Cheng, Y.2    Yang, J.3    Li, J.4    Liu, X.5    Wang, X.6    Wang, D.7    Krall, T.J.8    Delphin, E.S.9    Zhang, C.10
  • 14
    • 84899698561 scopus 로고    scopus 로고
    • MicroRNA-21 protects against ischemia-reperfusion and hypoxia-reperfusion-induced cardiocyte apoptosis via the phosphatase and tensin homolog/ akt-dependent mechanism
    • Yang, Q.; Yang, K.; Li, A. MicroRNA-21 protects against ischemia-reperfusion and hypoxia-reperfusion-induced cardiocyte apoptosis via the phosphatase and tensin homolog/ akt-dependent mechanism. Mol. Med. Rep. 2014, 9, 2213–2220
    • (2014) Mol. Med. Rep , vol.9 , pp. 2213-2220
    • Yang, Q.1    Yang, K.2    Li, A.3
  • 15
    • 84918526501 scopus 로고    scopus 로고
    • BTG2: A rising star of tumor suppressors (review)
    • Mao, B.; Zhang, Z.; Wang, G. BTG2: A rising star of tumor suppressors (review). Int. J. Oncol. 2015, 46, 459–464
    • (2015) Int. J. Oncol , vol.46 , pp. 459-464
    • Mao, B.1    Zhang, Z.2    Wang, G.3
  • 16
    • 34748813070 scopus 로고    scopus 로고
    • Molecular characterization of the BTG2 and BTG3 genes in fetal muscle development of pigs
    • Feng, Z.; Tang, Z.L.; Li, K.; Liu, B.; Yu, M.; Zhao, S.H. Molecular characterization of the BTG2 and BTG3 genes in fetal muscle development of pigs. Gene 2007, 403, 170–177
    • (2007) Gene , vol.403 , pp. 170-177
    • Feng, Z.1    Tang, Z.L.2    Li, K.3    Liu, B.4    Yu, M.5    Zhao, S.H.6
  • 17
    • 84880462310 scopus 로고    scopus 로고
    • Signals regulating necrosis of cardiomyoblast by BTG2/TIS21/PC3 via activation of GSK3β and opening of mitochondrial permeability transition pore in response to H2O2
    • Choi, Y.W.; Park, T.J.; Kim, H.S.; Lim, I.K. Signals regulating necrosis of cardiomyoblast by BTG2/TIS21/PC3 via activation of GSK3β and opening of mitochondrial permeability transition pore in response to H2O2. Biochem. Biophys. Res. Commun. 2013, 434, 559–565
    • (2013) Biochem. Biophys. Res. Commun , vol.434 , pp. 559-565
    • Choi, Y.W.1    Park, T.J.2    Kim, H.S.3    Lim, I.K.4
  • 18
    • 0033802643 scopus 로고    scopus 로고
    • Pegylated liposomal doxorubicin (Doxil): Reduced clinical cardiotoxicity in patients reaching or exceeding cumulative doses of 500 mg/m2
    • Safra, T.; Muggia, F.; Jeffers, S.; Tsao-Wei, D.D.; Groshen, S.; Lyass, O.; Henderson, R.; Berry, G.; Gabizon, A. Pegylated liposomal doxorubicin (doxil): Reduced clinical cardiotoxicity in patients reaching or exceeding cumulative doses of 500 mg/m2. Ann. Oncol. 2000, 11, 1029–1033
    • (2000) Ann. Oncol , vol.11 , pp. 1029-1033
    • Safra, T.1    Muggia, F.2    Jeffers, S.3    Tsao-Wei, D.D.4    Groshen, S.5    Lyass, O.6    Henderson, R.7    Berry, G.8    Gabizon, A.9
  • 19
    • 58149343451 scopus 로고    scopus 로고
    • Heat shock protein 20 interacting with phosphorylated akt reduces doxorubicin-triggered oxidative stress and cardiotoxicity
    • Fan, G.C.; Zhou, X.; Wang, X.; Song, G.; Qian, J.; Nicolaou, P.; Chen, G.; Ren, X.; Kranias, E.G. Heat shock protein 20 interacting with phosphorylated akt reduces doxorubicin-triggered oxidative stress and cardiotoxicity. Circ. Res. 2008, 103, 1270–1279
    • (2008) Circ. Res , vol.103 , pp. 1270-1279
    • Fan, G.C.1    Zhou, X.2    Wang, X.3    Song, G.4    Qian, J.5    Nicolaou, P.6    Chen, G.7    Ren, X.8    Kranias, E.G.9
  • 20
    • 84875475071 scopus 로고    scopus 로고
    • G-protein inactivator RGS6 mediates myocardial cell apoptosis and cardiomyopathy caused by doxorubicin
    • Yang, J.; Maity, B.; Huang, J.; Gao, Z.; Stewart, A.; Weiss, R.M.; Anderson, M.E.; Fisher, R.A. G-protein inactivator RGS6 mediates myocardial cell apoptosis and cardiomyopathy caused by doxorubicin. Cancer Res. 2013, 73, 1662–1667
    • (2013) Cancer Res , vol.73 , pp. 1662-1667
    • Yang, J.1    Maity, B.2    Huang, J.3    Gao, Z.4    Stewart, A.5    Weiss, R.M.6    Anderson, M.E.7    Fisher, R.A.8
  • 21
    • 84861545875 scopus 로고    scopus 로고
    • Heat shock protein 25-enriched plasma transfusion preconditions the heart against doxorubicin-induced dilated cardiomyopathy in mice
    • Krishnamurthy, K.; Kanagasabai, R.; Druhan, L.J.; Ilangovan, G. Heat shock protein 25-enriched plasma transfusion preconditions the heart against doxorubicin-induced dilated cardiomyopathy in mice. J. Pharmacol. Exp. Ther. 2012, 341, 829–839
    • (2012) J. Pharmacol. Exp. Ther , vol.341 , pp. 829-839
    • Krishnamurthy, K.1    Kanagasabai, R.2    Druhan, L.J.3    Ilangovan, G.4
  • 23
    • 84923095860 scopus 로고    scopus 로고
    • Combination treatment with doxorubicin and microRNA-21 inhibitor synergistically augments anticancer activity through upregulation of tumor suppressing genes
    • Zhang, S.; Han, L.; Wei, J.; Shi, Z.; Pu, P.; Zhang, J.; Yuan, X.; Kang, C. Combination treatment with doxorubicin and microRNA-21 inhibitor synergistically augments anticancer activity through upregulation of tumor suppressing genes. Int. J. Oncol. 2015, 46, 1589–1600
    • (2015) Int. J. Oncol , vol.46 , pp. 1589-1600
    • Zhang, S.1    Han, L.2    Wei, J.3    Shi, Z.4    Pu, P.5    Zhang, J.6    Yuan, X.7    Kang, C.8
  • 25
    • 84894084047 scopus 로고    scopus 로고
    • MicroRNA-21 promotes cardiac fibrosis and development of heart failure with preserved left ventricular ejection fraction by up-regulating BCL-2
    • Dong, S.; Ma, W.; Hao, B.; Hu, F.; Yan, L.; Yan, X.; Wang, Y.; Chen, Z.; Wang, Z. MicroRNA-21 promotes cardiac fibrosis and development of heart failure with preserved left ventricular ejection fraction by up-regulating BCL-2. Int. J. Clin. Exp. Pathol. 2014, 7, 565–574
    • (2014) Int. J. Clin. Exp. Pathol , vol.7 , pp. 565-574
    • Dong, S.1    Ma, W.2    Hao, B.3    Hu, F.4    Yan, L.5    Yan, X.6    Wang, Y.7    Chen, Z.8    Wang, Z.9
  • 26
    • 0035057256 scopus 로고    scopus 로고
    • The gene PC3 (TIS21/BTG2), prototype member of the PC3/BTG/TOB family: Regulator in control of cell growth, differentiation, and DNA repair?
    • Tirone, F. The gene PC3 (TIS21/BTG2), prototype member of the PC3/BTG/TOB family: Regulator in control of cell growth, differentiation, and DNA repair? J. Cell. Physiol. 2001, 187, 155–165
    • (2001) J. Cell. Physiol , vol.187 , pp. 155-165
    • Tirone, F.1
  • 27
    • 84878728517 scopus 로고    scopus 로고
    • BTG2 inhibits the proliferation, invasion, and apoptosis of MDA-MB-231 triple-negative breast cancer cells
    • Zhang, Y.J.; Wei, L.; Liu, M.; Li, J.; Zheng, Y.Q.; Gao, Y.; Li, X.R. BTG2 inhibits the proliferation, invasion, and apoptosis of MDA-MB-231 triple-negative breast cancer cells. Tumour Biol. 2013, 34, 1605–1613
    • (2013) Tumour Biol , vol.34 , pp. 1605-1613
    • Zhang, Y.J.1    Wei, L.2    Liu, M.3    Li, J.4    Zheng, Y.Q.5    Gao, Y.6    Li, X.R.7
  • 28
    • 85027948036 scopus 로고    scopus 로고
    • Effects of BTG2 on proliferation inhibition and anti-invasion in human lung cancer cells
    • Wei, S.; Hao, C.; Li, X.; Zhao, H.; Chen, J.; Zhou, Q. Effects of BTG2 on proliferation inhibition and anti-invasion in human lung cancer cells. Tumour Biol. 2012, 33, 1223–1230
    • (2012) Tumour Biol , vol.33 , pp. 1223-1230
    • Wei, S.1    Hao, C.2    Li, X.3    Zhao, H.4    Chen, J.5    Zhou, Q.6
  • 29
    • 68149137764 scopus 로고    scopus 로고
    • Regulation of the cell cycle gene, BTG2, by MIR-21 in human laryngeal carcinoma
    • Liu, M.; Wu, H.; Liu, T.; Li, Y.; Wang, F.; Wan, H.; Li, X.; Tang, H. Regulation of the cell cycle gene, BTG2, by MIR-21 in human laryngeal carcinoma. Cell Res. 2009, 19, 828–837
    • (2009) Cell Res , vol.19 , pp. 828-837
    • Liu, M.1    Wu, H.2    Liu, T.3    Li, Y.4    Wang, F.5    Wan, H.6    Li, X.7    Tang, H.8
  • 30
    • 84879394866 scopus 로고    scopus 로고
    • Nucleolin protects the heart from ischaemia-reperfusion injury by up-regulating heat shock protein 32
    • Jiang, B.; Zhang, B.; Liang, P.; Chen, G.; Zhou, B.; Lv, C.; Tu, Z.; Xiao, X. Nucleolin protects the heart from ischaemia-reperfusion injury by up-regulating heat shock protein 32. Cardiovas. Res. 2013, 99, 92–101
    • (2013) Cardiovas. Res , vol.99 , pp. 92-101
    • Jiang, B.1    Zhang, B.2    Liang, P.3    Chen, G.4    Zhou, B.5    Lv, C.6    Tu, Z.7    Xiao, X.8
  • 32
    • 79957532361 scopus 로고    scopus 로고
    • Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53
    • Zhang, C.; Feng, Y.; Qu, S.; Wei, X.; Zhu, H.; Luo, Q.; Liu, M.; Chen, G.; Xiao, X. Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53. Cardiovas. Res. 2011, 90, 538–545.
    • (2011) Cardiovas. Res , vol.90 , pp. 538-545
    • Zhang, C.1    Feng, Y.2    Qu, S.3    Wei, X.4    Zhu, H.5    Luo, Q.6    Liu, M.7    Chen, G.8    Xiao, X.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.