Development and polarization of cationic amino acid transporters and regulators in the human placenta

American Journal of Physiology - Cell Physiology

Volumn 278, Issue 6 47-6, 2000, Pages

  Ayuk, Paul T Y ^a   Sibley, Colin P ^a   Donnai, Paul ^a   D'Souza, Stephen ^a   Glazier, Jocelyn D ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

4F2hc; CAT 1; CAT 4; Gestational change; L arginine; RBAT

Indexed keywords

AMINO ACID TRANSPORT; ARTICLE; BASEMENT MEMBRANE; HUMAN; HUMAN CELL; HUMAN TISSUE; MEMBRANE VESICLE; MICHAELIS CONSTANT; MICROVILLUS; PLACENTA; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYNCYTIOTROPHOBLAST; WESTERN BLOTTING;

FELIS CATUS; MAMMALIA;

EID: 0033916921     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.2000.278.6.c1162     Document Type: Article

References (12)

1. Bertran J, Magagnin S, Werner A, Markovich D, Biber J, Testar X, Zorzano A, Kuhn L, Palacin M, and Murer H. Stimulation of system y+ like amino acid transport by the heavy chain of human 4F2 surface antigen in xenopus oocytes. Proc Natl Acad Sci USA 89: 5606-5610, 1992.
2. Bertran J, Werner A, Chillaron J, Nunes V, Biber J, Testar X, Zorzano A, Estivill X, Murer H, and Palacin M. Expression cloning of a human renal cDNA that induces high affinity transport of L-cystine shared with dibasic amino acids in xenopus oocytes. J Biol Chem 268: 14842-14849, 1993.
3. Bogle RG, Baydoun A, Pearson JD, Moncada S, and Mann G. L-Arginine transport is increased in macrophages generating nitric oxide. Biochem J 284: 15-18, 1992.
4. Chaudhuri G, Cuevas J, Buga GM, and Ignarro LJ. NO is more important than PGI2 in maintaining low vascular tone in feto-placental vessels. Am J Physiol Heart Circ Physiol 265: H2036-H2043, 1993.
5. Chillaron J, Estevez R, Mora C, Wagner CA, Suessbrich H, Lang F, Gelpi JS, Testar X, Busch A, Zorzano A, and Palacin M. Obligatory amino acid exchange by systems b0+-like and y+L-like. J Biol Chem 271: 17761-17770, 1996.
6. Chomczynski P and Sacchi N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159, 1987.
7. Gloss EI, Graf P, Habermeier A, Cunningham J, and Forstermann U. Human cationic amino acid transporters hCAT-1, hCAT-2A and hCAT-2B: three related carriers with distinct transport properties. Biochem J 36: 6462-6468, 1997.
8. Closs EI, Scheid JS, Sharafi M, and Forstermann U. Differences in the L-arginine supply of nitric oxide synthases in macrophages and endothelial cells (Abstract). J Physiol (Lond) 506: 29P, 1998.
9. Cynober L, Le Boucher J, and Vasson M. Arginine metabolism in mammals. J Nutr Biochem 6: 402-413, 1995.
10. Deves R, Angelo S, and Chavez P. N-ethylmaleimide discriminates between two lysine transport systems in human erythrocytes. J Physiol (Lond) 468: 753-766, 1993.
11. Deves R and Boyd CAR. Transporters for cationic amino acids in animal cells: discovery, structure and function. Physiol Rev 78: 487-545, 1998.
12. Deves R, Chavez P, and Boyd CAR. Identification of a new transport system (y+L) in human erythrocytes that recognises lysine and leucine with high affinity. J Physiol (Lond) 454: 491-501, 1992.