T cells expressing a LMP1-specific chimeric antigen receptor mediate antitumor effects against LMP1-positive nasopharyngeal carcinoma cells in vitro and in vivo

Journal of Biomedical Research

Volumn 28, Issue 6, 2014, Pages 468-475

  Tang, Xiaojun ^a   Zhou, Yan ^b   Li, Wenjie ^c   Tang, Qi ^a   Chen, Renjie ^c   Zhu, Jin ^a,d   Feng, Zhenqing ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b Aoyang Hospital   (China)

^c THE SECOND AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^d Huadong Medical Institute of Biotechniques   (China)

Author keywords

Adoptive T cell therapy; Chimeric antigen receptor; EBV; LMP1; Nasopharyngeal carcinoma

Indexed keywords

CD28 ANTIGEN; CHIMERIC ANTIGEN RECEPTOR; GAMMA INTERFERON; INTERLEUKIN 2; LATENT MEMBRANE PROTEIN 1; LENTIVIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CD3+ T LYMPHOCYTE; CELL ACTIVATION; CELL THERAPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOLYSIS; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NASOPHARYNX CARCINOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; TUMOR GROWTH; TUMOR XENOGRAFT;

EID: 84933529811     PISSN: 16748301     EISSN: None     Source Type: Journal    
DOI: 10.7555/JBR.28.20140066     Document Type: Article

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