Epstein-Barr virus latent membrane protein 1 mRNA is expressed in a significant proportion of patients with chronic lymphocytic leukemia

Cancer

Volumn 116, Issue 4, 2010, Pages 880-887

  Tarrand, Jeffrey J ^a   Keating, Michael J ^a   Tsimberidou, Apostolia M ^a   O'Brien, Susan ^a   LaSala, Rocco P ^a   Han, Xiang Yang ^a   Bueso Ramos, Carlos E ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Chronic lymphocytic leukemia; Epstein Barr virus; Gene expression; LMP 1 protein; Transcription

Indexed keywords

LATENT MEMBRANE PROTEIN 1; MESSENGER RNA;

ADULT; AGED; ARTICLE; BONE MARROW; BURKITT LYMPHOMA; CANCER GROWTH; CANCER PATIENT; CHRONIC LYMPHATIC LEUKEMIA; COHORT ANALYSIS; CONTROLLED STUDY; EPSTEIN BARR VIRUS; FEMALE; GENE EXPRESSION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HODGKIN DISEASE; HUMAN; HUMAN CELL; IN VITRO STUDY; LMP1 GENE; MAJOR CLINICAL STUDY; MALE; NONHUMAN; OUTCOME ASSESSMENT; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA TRANSCRIPTION; SOLID TUMOR; VIRUS GENE;

ADULT; AGED; AGED, 80 AND OVER; BONE MARROW; CELL LINE, TUMOR; FEMALE; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MALE; MIDDLE AGED; RNA, MESSENGER; RNA, VIRAL; VIRAL MATRIX PROTEINS;

EID: 76249108359     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.24839     Document Type: Article

References (28)

1. Cheson BD, Bennett JM, Grever M, et al. National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment. Blood. 1996;87:4990-4997.
2. Lampert IA, Wotherspoon A, Van Noorden S, Hasserjian RP. High expression of CD23 in the proliferation centers of chronic lymphocytic leukemia in lymph nodes and spleen. Hum Pathol. 1999;30:648-654.
3. Messmer BT, Messmer D, Allen SL, et al. In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells. J Clin Invest. 2005;115:755-764.
4. Obermann EC, Went P, Tzankov A, et al. Cell cycle phase distribution analysis in chronic lymphocytic leukaemia: a significant number of cells reside in early G1-phase. J Clin Pathol. 2007;60:794-797.
5. Tsimberidou AM, Keating MJ, Bueso-Ramos CE, Kurzrock R. Epstein-Barr virus in patients with chronic lymphocytic leukemia: a pilot study. Leuk Lymphoma. 2006;47:827-836.
6. Tsimberidou AM, Keating MJ. Richter's transformation in chronic lymphocytic leukemia. Semin Oncol. 2006;33:250-256.
7. Bueso-Ramos CE, Ferrajoli A, Medeiros LJ, Keating MJ, Estrov Z. Aberrant morphology, proliferation, and apoptosis of B-cell chronic lymphocytic leukemia cells. Hematology. 2004;9:279-286.
8. Ansell SM, Li CY, Lloyd RV, Phyliky RL. Epstein-Barr virus infection in Richter's transformation. Am J Hematol. 1999;60:99-104.
9. Tsimberidou AM, O'Brien S, Kantarjian HM, et al. Hodgkin transformation of chronic lymphocytic leukemia. Cancer. 2006;107:1294-1302.
10. Lu ZX, Ma XQ, Yang LF, et al. DNAzymes targeted to EBV-encoded latent membrane protein induce apoptosis and enhance radiosensitivity in nasopharyngeal carcinoma. Cancer Lett. 2005;265:226-238.
11. D'Souza BN, Edelstein LC, Pegman PM, et al. Nuclear factor kappa B-dependent activation of the antiapoptotic bfl-1 gene by the Epstein-Barr virus latent membrane protein 1 and activated CD40 receptor. J Virol. 2004;78:1800-1816.
12. Schlette E, Bueso-Ramos C, Giles F, et al. Mature B-cell leukemias with more than 55% prolymphocytes. A heterogeneous group that includes an unusual variant of mantle cell lymphoma. Am J Clin Pathol. 2001;115:571-581.
13. Boom R, Sol CJA, Saliman MMM, et al. Rapid and simple method for purification of nucleic acids. J Clin Microbiol. 1990;28:495-503.
14. Brink AA, Vervoort MB, Middeldrop JM, Meijer CJ, Van den Brule AJ. Nucleic acid sequence-based amplification of spliced and unspliced Epstein-Barr latent transcripts. J Clin Microbiol. 1998;36:3164.
15. Greijer AE, Dekkers CA, Middeldorp JM. Human cytomegalovirus virions differentially incorporate viral and host cell RNA during the assembly process. J Virol. 2000;74:9078-9082.
16. Patterson SS, Casper ET, Garcia-Rubio I, Smith MC, Paul JH. Increased precision of microbial RNA quantification using NASBA with an internal control. J Microbiol Methods. 2005;60:343-352.
17. Dixon EP, King LM, Adams MD, et al. Isolation of RNA from residual BD SurePath liquid-based cytology specimens and detection of EPV E6/E7 mRNA using the PreTectt HPVpProofer assay. J Virol Methods. 2008;154:220-222.
18. Deiman B, van Aarle P, Sillekens P. Characteristics and applications of nucleic acid sequence based amplification. Mol Biotechnol. 2007;20:163-179.
19. Kirkman TW. Statistics to use. Monograph online, 1996. Available at: http://www.phisics.csbsju.edu/stats/ Accessed March 18, 2009.
20. Wu TC, Mann RB, Epstein JI, et al. Abundant expression of EBER1 small nuclear RNA in nasopharyngeal carcinoma. A morphologically distinctive target for detection of Epstein-Barr virus in formalin-fixed paraffin-embedded carcinoma specimens. Am J Pathol. 1991;138:1461-1469.
21. Korsmeyer SJ. BCL-2 gene family and the regulation of programmed cell death. Cancer Res. 1999;59(7 suppl): 1693s-1700s.
22. Bogner C, Schneller F, Hipp S, et al. Cycling B-CLL cells are highly susceptible to inhibition of the proteasome: involvement of p27, early D-type cyclins, Bax, and caspase-dependent and -independent pathways. Exp Hematol. 2003;31:218-225.
23. Inamdar KV, O'Brien S, Sen S, et al. Aurora: a kinase nuclear expression in chronic lymphocytic leukemia. Mod Pathol. 2008;21:1428-1435.
24. Blay JY, Voorzanger N, Favrot M, Burdin N, Rousset F, Banchereau J. Presence of Epstein-Barr virus viral interleukin 10 in the serum of patients with non-human-immunodeficiency-virus-related diffuse large-cell non-Hodgkin's lymphomas. Blood. 1995;86:4702-4704.
25. Fayad L, Keating MJ, Reuben JM, et al. Interleukin 6 and interleukin 10 levels in chronic lymphocytic leukemia: correlation with phenotypic characteristics and outcome. Blood. 2001;97:256-263.
26. Lazzarino M, Orlandi E, Baldanti F, et al. The immunosuppression and potential of rEBV reactivation of fludarabine combined with cyclophosphamide and dexamethasone in patients with lymphoproliferative disorders. Br J Haematol. 199;107:877-882.
27. Laytragoon-Lewin N, Chen F, Avila-Carino J, et al. Epstein Barr virus (EBV)-carrying cells of a chronic lymphocytic leukemia (CLL) subpopulation express EBNA1 and LMPs but not EBNA2 in vivo. Int J Cancer. 1995;63:486-490.
28. Laytragoon-Lewin N, Chen F, Castro J, Avila-Carino J, Lewin F. Cytokines and Epstein Barr virus (EBV) genes expression in blood chronic lymphocytic leukemia (CLL) cells and their immortalized CLL cell lines. Anticancer Res. 2003;23:4017-4022.