Bicuspid aortic valve: Phosphorylation of c-Kit and downstream targets are prognostic for future aortopathy

European Journal of Cardio-thoracic Surgery

Volumn 46, Issue 5, 2014, Pages 831-839

  Grewal, Nimrat ^a   Gittenberger de Groot, Adriana C ^a   DeRuiter, Marco C ^a   Klautz, Robert J M ^a   Poelmann, Robert E ^a   Duim, Sjoerd ^a   Lindeman, Johannes H N ^a   Koenraadt, Wilke M C ^a   Jongbloed, Monique R M ^a   Mohamed, Salah A ^b   Sievers, Hans Hinrich ^b   Bogers, Ad J J C ^c   Goumans, Marie José ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF LÜBECK   (Germany)

^c ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Aneurysm; Aorta; Congenital; Heart defects; Pathology

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; GELATINASE B; HYPOXIA INDUCIBLE FACTOR 1ALPHA; SMAD2 PROTEIN; STEM CELL FACTOR; TRANSFORMING GROWTH FACTOR BETA; BIOLOGICAL MARKER; NITRIC OXIDE; STEM CELL FACTOR RECEPTOR;

ADULT; AORTA DISEASE; AORTA VALVE DISEASE; AORTA WALL; AORTIC VALVE REPAIR; AORTOPATHY; ARTERIAL WALL THICKNESS; ARTICLE; BICUSPID AORTIC VALVE; CELL DIFFERENTIATION; CONTROLLED STUDY; FEMALE; HEMODYNAMICS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRICUSPID AORTIC VALVE; VASCULAR REMODELING; VASODILATATION; AGED; AORTA; AORTA VALVE; AORTIC DISEASES; CHEMISTRY; COHORT ANALYSIS; CONGENITAL MALFORMATION; METABOLISM; MIDDLE AGED; PHOSPHORYLATION; VALVULAR HEART DISEASE; VASCULAR SMOOTH MUSCLE;

ADULT; AGED; AORTA; AORTIC DISEASES; AORTIC VALVE; BIOLOGICAL MARKERS; COHORT STUDIES; FEMALE; HEART VALVE DISEASES; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; PHOSPHORYLATION; PROGNOSIS; PROTO-ONCOGENE PROTEINS C-KIT; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 84933524044     PISSN: 10107940     EISSN: 1873734X     Source Type: Journal    
DOI: 10.1093/ejcts/ezu319     Document Type: Article

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