Endothelial Nitric Oxide Synthase in Bicuspid Aortic Valve Disease

Annals of Thoracic Surgery

Volumn 83, Issue 4, 2007, Pages 1290-1294

  Aicher, Diana ^a   Urbich, Carmen ^b   Zeiher, Andreas ^b   Dimmeler, Stefanie ^b   Schäfers, Hans Joachim ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE;

ADULT; AGED; ANALYTIC METHOD; AORTA DILATATION; AORTA VALVE DISEASE; AORTA WALL; ARTICLE; CELL LYSATE; CONTROLLED STUDY; CORRELATION COEFFICIENT; FEMALE; HEART VALVE REGURGITATION; HEART VALVE STENOSIS; HUMAN; IMMUNOPRECIPITATION; MAJOR CLINICAL STUDY; MALE; MITRAL VALVE; MITRAL VALVE DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRICUSPID VALVE; WESTERN BLOTTING;

ADULT; AGED; AGED, 80 AND OVER; AORTIC VALVE; AORTIC VALVE INSUFFICIENCY; AORTIC VALVE STENOSIS; BIOLOGICAL MARKERS; DILATATION, PATHOLOGIC; FEMALE; HUMANS; MALE; MIDDLE AGED; MITRAL VALVE; NITRIC OXIDE SYNTHASE TYPE III; PROBABILITY; PROGNOSIS; SAMPLING STUDIES; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; TISSUE CULTURE TECHNIQUES; TRICUSPID VALVE;

EID: 33947304677     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2006.11.086     Document Type: Article

References (19)

1. Ando M., Okita Y., Morota T., and Takamoto S. Thoracic aortic aneurysm associated with congenital bicuspid aortic valve. Cardiovasc Surg 6 (1998) 629-634
2. Nkomo V.T., Enriquez-Sarano M., Ammash N.M., et al. Bicuspid aortic valve associated with aortic dilatation: a community-based study. Arterioscler Thromb Vasc Biol 23 (2003) 351-356
3. Holman E. The obscure physiology of poststenotic dilatation: its relation to the development of aneurysms. J Thorac Surg 28 (1954) 109-133
4. Gale A.N., McKusick V.A., Hutchins G.M., and Gott V.L. Familial congenital bicuspid aortic valve: secondary calcific aortic stenosis and aortic aneurysm. Chest 72 (1977) 668-670
5. Keane M.G., Wiegers S.E., Plappert T., Pochettino A., Bavaria J.E., and Sutton M.G. Bicuspid aortic valves are associated with aortic dilatation out of proportion to coexistent valvular lesions. Circulation 102 (2000) III35-III39
6. Nistri S., Sorbo M.D., Marin M., Palisi M., Scognamiglio R., and Thiene G. Aortic root dilatation in young men with normally functioning bicuspid aortic valves. Heart 82 (1999) 19-22
7. Pachulski R.T., Weinberg A.L., and Chan K.L. Aortic aneurysm in patients with functionally normal or minimally stenotic bicuspid aortic valves. Am J Cardiol 67 (1991) 781-782
8. Bauer M., Pasic M., Meyer R., et al. Morphometric analysis of aortic media in patients with bicuspid and tricuspid aortic valve. Ann Thorac Surg 74 (2002) 58-62
9. De Sa M., Moshkovitz Y., Butany J., and David T.E. Histologic abnormalities of the ascending aorta and pulmonary trunk in patients with bicuspid aortic valve disease: clinical relevance to the Ross procedure. J Thorac Cardiovasc Surg 118 (1999) 588-596
10. Lindsay Jr. J. Coarctation of the aorta, bicuspid aortic valve and abnormal ascending aortic wall. Am J Cardiol 61 (1988) 182-184
11. Bonderman D., Gharehbaghi-Schnell E., Wollenek G., Maurer G., Baumgartner H., and Lang I.M. Mechanisms underlying aortic dilatation in congenital aortic valve malformation. Circulation 99 (1999) 2138-2143
12. Lee T.C., Zhao Y.D., Courtman D.W., and Stewart D.J. Abnormal aortic valve development in mice lacking endothelial nitric oxide synthase. Circulation 101 (2000) 2345-2348
13. Kuhlencordt P.J., Gyurko R., Han F., et al. Accelerated atherosclerosis, aortic aneurysm formation and ischemic heart disease in apolipoprotein E/endothelial nitric oxide synthase double-knockout mice. Circulation 104 (2001) 448-454
14. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72 (1976) 248-254
15. Ward C. Clinical significance of the bicuspid aortic valve. Heart 83 (2000) 81-85
16. Edwards W.D., Leaf D.S., and Edwards J.E. Dissecting aortic aneurysm associated with congenital bicuspid aortic valve. Circulation 57 (1978) 1022-1025
17. Huang P.L., Huang Z., Mashimo H., et al. Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature 377 6546 (1995) 239-242
18. Chen J., Kuhlencordt P.J., Astern J., Gyurko R., and Huang P.L. Hypertension does not account for the accelerated atherosclerosis and development of aneurysms in male apolipoprotein E/endothelial nitric oxide synthase double knockout mice. Circulation 104 (2001) 2391-2394
19. Lubrano V., Vassalle C., Blandizzi C., et al. The effect of lipoproteins on endothelial nitric oxide synthase is modulated by lipoperoxides. Eur J Clin Invest 33 (2003) 117-125