메뉴 건너뛰기




Volumn 11, Issue 3, 2015, Pages 657-670

Multifunctional ultrasmall nanoplatforms for vascular-targeted interstitial photodynamic therapy of brain tumors guided by real-time MRI

Author keywords

Brain tumor; iPDT; Multifunctional nanoplatforms; Real time MRI; Targeting

Indexed keywords

BRAIN; ENDOTHELIAL CELLS; NANOMAGNETICS; NANOPARTICLES; PHOTODYNAMIC THERAPY; PHOTOSENSITIZERS; TUMORS;

EID: 84933510120     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2014.12.007     Document Type: Article
Times cited : (53)

References (64)
  • 1
    • 34447257445 scopus 로고    scopus 로고
    • Interstitial photodynamic therapy of nonresectable malignant glioma recurrences using 5-aminolevulinic acid induced protoporphyrin IX
    • Beck T.J., Kreth F.W., Beyer W., Mehrkens J.H., Obermeier A., Stepp H., et al. Interstitial photodynamic therapy of nonresectable malignant glioma recurrences using 5-aminolevulinic acid induced protoporphyrin IX. Lasers Surg Med 2007, 39:386-393.
    • (2007) Lasers Surg Med , vol.39 , pp. 386-393
    • Beck, T.J.1    Kreth, F.W.2    Beyer, W.3    Mehrkens, J.H.4    Obermeier, A.5    Stepp, H.6
  • 2
    • 0033795533 scopus 로고    scopus 로고
    • Optimal light dose for interstitial photodynamic therapy in treatment for malignant brain tumors
    • Krishnamurthy S., Powers S.K., Witmer P., Brown T. Optimal light dose for interstitial photodynamic therapy in treatment for malignant brain tumors. Lasers Surg Med 2000, 27:224-234.
    • (2000) Lasers Surg Med , vol.27 , pp. 224-234
    • Krishnamurthy, S.1    Powers, S.K.2    Witmer, P.3    Brown, T.4
  • 3
    • 38649127265 scopus 로고    scopus 로고
    • Long-sustaining response in a patient with non-resectable, distant recurrence of glioblastoma multiforme treated by interstitial photodynamic therapy using 5-ALA: case report
    • Stummer W., Beck T., Beyer W., Mehrkens J.H., Obermeier A., Etminan N., et al. Long-sustaining response in a patient with non-resectable, distant recurrence of glioblastoma multiforme treated by interstitial photodynamic therapy using 5-ALA: case report. J Neurooncol 2008, 87:103-109.
    • (2008) J Neurooncol , vol.87 , pp. 103-109
    • Stummer, W.1    Beck, T.2    Beyer, W.3    Mehrkens, J.H.4    Obermeier, A.5    Etminan, N.6
  • 4
    • 33750971759 scopus 로고    scopus 로고
    • Combination of FOSCAN® mediated fluorescence guided resection and photodynamic treatment as new therapeutic concept for malignant brain tumors
    • Kostron H., Fiegele T., Akatuna E. Combination of FOSCAN® mediated fluorescence guided resection and photodynamic treatment as new therapeutic concept for malignant brain tumors. Med Laser Appl 2006, 21:285-290.
    • (2006) Med Laser Appl , vol.21 , pp. 285-290
    • Kostron, H.1    Fiegele, T.2    Akatuna, E.3
  • 6
    • 52949115237 scopus 로고    scopus 로고
    • ALA and Photofrin fluorescence-guided resection and repetitive PDT in glioblastoma multiforme: a single centre Phase III randomised controlled trial
    • Eljamel M.S., Goodman C., Moseley H. ALA and Photofrin fluorescence-guided resection and repetitive PDT in glioblastoma multiforme: a single centre Phase III randomised controlled trial. Lasers Med Sci 2008, 23:361-367.
    • (2008) Lasers Med Sci , vol.23 , pp. 361-367
    • Eljamel, M.S.1    Goodman, C.2    Moseley, H.3
  • 7
    • 60949093553 scopus 로고    scopus 로고
    • Fluorescence image-guided surgery and repetitive photodynamic therapy in brain metastatic malignant melanoma
    • Zilidis G., Aziz F., Telara S., Eljamel M.S. Fluorescence image-guided surgery and repetitive photodynamic therapy in brain metastatic malignant melanoma. Photodiagnosis Photodyn Ther 2008, 5:264-276.
    • (2008) Photodiagnosis Photodyn Ther , vol.5 , pp. 264-276
    • Zilidis, G.1    Aziz, F.2    Telara, S.3    Eljamel, M.S.4
  • 9
    • 78649667673 scopus 로고    scopus 로고
    • 5-Aminolevulinic acid-induced protoporphyrin IX levels in tissue of human malignant brain tumors
    • Johansson A., Palte G., Schnell O., Tonn J.C., Herms J., Stepp H., et al. 5-Aminolevulinic acid-induced protoporphyrin IX levels in tissue of human malignant brain tumors. Photochem Photobiol 2010, 86:1373-1378.
    • (2010) Photochem Photobiol , vol.86 , pp. 1373-1378
    • Johansson, A.1    Palte, G.2    Schnell, O.3    Tonn, J.C.4    Herms, J.5    Stepp, H.6
  • 10
    • 0141644318 scopus 로고    scopus 로고
    • Photodynamic therapy with photofrin in combination with buthionine sulfoximine (BSO) of human glioma in the nude rat
    • Jiang F., Robin A.M., Katakowski M., Tong L., Espiritu M., Singh G., Jiang F., et al. Photodynamic therapy with photofrin in combination with buthionine sulfoximine (BSO) of human glioma in the nude rat. Lasers Med Sci 2003, 18:128-133.
    • (2003) Lasers Med Sci , vol.18 , pp. 128-133
    • Jiang, F.1    Robin, A.M.2    Katakowski, M.3    Tong, L.4    Espiritu, M.5    Singh, G.6    Jiang, F.7
  • 11
    • 33645986455 scopus 로고    scopus 로고
    • Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial
    • ALA-Glioma Study Group
    • Stummer W., Pichlmeier U., Meinel T., Wiestler O.D., Zanella F., Reulen H.J. Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol 2006, 7:392-401. ALA-Glioma Study Group.
    • (2006) Lancet Oncol , vol.7 , pp. 392-401
    • Stummer, W.1    Pichlmeier, U.2    Meinel, T.3    Wiestler, O.D.4    Zanella, F.5    Reulen, H.J.6
  • 12
    • 0035497647 scopus 로고    scopus 로고
    • MTHPC-mediated photodynamic diagnosis of malignant brain tumors
    • Zimmermann A., Ritsch-Marte M., Kostron H. mTHPC-mediated photodynamic diagnosis of malignant brain tumors. Photochem Photobiol 2001, 74:611-616.
    • (2001) Photochem Photobiol , vol.74 , pp. 611-616
    • Zimmermann, A.1    Ritsch-Marte, M.2    Kostron, H.3
  • 13
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1995, 1:27-31.
    • (1995) Nat Med , vol.1 , pp. 27-31
    • Folkman, J.1
  • 15
    • 17444390144 scopus 로고    scopus 로고
    • Antiangiogenic photodynamic therapy (PDT) by using long-circulating liposomes modified with peptide specific to angiogenic vessels
    • Ichikawa K., Hikita T., Maeda N., Yonezawa S., Takeuchi Y., Asai T., et al. Antiangiogenic photodynamic therapy (PDT) by using long-circulating liposomes modified with peptide specific to angiogenic vessels. Biochim Biophys Acta 2005, 1669:69-74.
    • (2005) Biochim Biophys Acta , vol.1669 , pp. 69-74
    • Ichikawa, K.1    Hikita, T.2    Maeda, N.3    Yonezawa, S.4    Takeuchi, Y.5    Asai, T.6
  • 16
    • 32944481745 scopus 로고    scopus 로고
    • Tumor vascular permeabilization by vascular-targeting photosensitization: effects, mechanism, and therapeutic implications
    • Chen B., Pogue B.W., Luna J.M., Hardman R.L., Hoopes P.J., Hasan T., et al. Tumor vascular permeabilization by vascular-targeting photosensitization: effects, mechanism, and therapeutic implications. Clin Cancer Res 2006, 12:917-923.
    • (2006) Clin Cancer Res , vol.12 , pp. 917-923
    • Chen, B.1    Pogue, B.W.2    Luna, J.M.3    Hardman, R.L.4    Hoopes, P.J.5    Hasan, T.6
  • 17
    • 0034112132 scopus 로고    scopus 로고
    • Vascular damage after photodynamic therapy of solid tumors: a view and comparison of effect in pre-clinical and clinical models at the University of Louisville
    • Fingar V.H., Taber S.W., Haydon P.S., Harrison L.T., Kempf S.J., Wieman T.J., et al. Vascular damage after photodynamic therapy of solid tumors: a view and comparison of effect in pre-clinical and clinical models at the University of Louisville. In Vivo 2000, 14:93-100.
    • (2000) In Vivo , vol.14 , pp. 93-100
    • Fingar, V.H.1    Taber, S.W.2    Haydon, P.S.3    Harrison, L.T.4    Kempf, S.J.5    Wieman, T.J.6
  • 18
    • 19344373966 scopus 로고    scopus 로고
    • Studies of a vascular-acting photosensitizer, Pd-bacteriopheophorbide (Tookad), in normal canine prostate and spontaneous canine prostate cancer
    • Huang Z., Chen Q., Luck D., Beckers J., Wilson B.C., Trncic N., et al. Studies of a vascular-acting photosensitizer, Pd-bacteriopheophorbide (Tookad), in normal canine prostate and spontaneous canine prostate cancer. Lasers Surg Med 2005, 36:390-397.
    • (2005) Lasers Surg Med , vol.36 , pp. 390-397
    • Huang, Z.1    Chen, Q.2    Luck, D.3    Beckers, J.4    Wilson, B.C.5    Trncic, N.6
  • 19
    • 0028006629 scopus 로고
    • Effects of photodynamic therapy using mono-l-aspartyl chlorin e6 on vessel constriction, vessel leakage, and tumor response
    • McMahon K.S., Wieman T.J., Moore P.H., Fingar V.H. Effects of photodynamic therapy using mono-l-aspartyl chlorin e6 on vessel constriction, vessel leakage, and tumor response. Cancer Res 1994, 54:5374-5379.
    • (1994) Cancer Res , vol.54 , pp. 5374-5379
    • McMahon, K.S.1    Wieman, T.J.2    Moore, P.H.3    Fingar, V.H.4
  • 21
    • 0026793238 scopus 로고
    • The role of microvascular damage in photodynamic therapy: the effect of treatment on vessel constriction, permeability, and leukocyte adhesion
    • Fingar V.H., Wieman T.J., Wiehle S.A., Cerrito P.B. The role of microvascular damage in photodynamic therapy: the effect of treatment on vessel constriction, permeability, and leukocyte adhesion. Cancer Res 1992, 52:4914-4921.
    • (1992) Cancer Res , vol.52 , pp. 4914-4921
    • Fingar, V.H.1    Wieman, T.J.2    Wiehle, S.A.3    Cerrito, P.B.4
  • 22
    • 36148969690 scopus 로고    scopus 로고
    • Structure-function analysis of the antiangiogenic ATWLPPR peptide inhibiting VEGF(165) binding to neuropilin-1 and molecular dynamics simulations of the ATWLPPR/neuropilin-1 complex
    • Starzec A., Ladam P., Vassy R., Badache S., Bouchemal N., Navaza A., Starzec A., et al. Structure-function analysis of the antiangiogenic ATWLPPR peptide inhibiting VEGF(165) binding to neuropilin-1 and molecular dynamics simulations of the ATWLPPR/neuropilin-1 complex. Peptides 2007, 28:2397-2402.
    • (2007) Peptides , vol.28 , pp. 2397-2402
    • Starzec, A.1    Ladam, P.2    Vassy, R.3    Badache, S.4    Bouchemal, N.5    Navaza, A.6    Starzec, A.7
  • 23
    • 33344469536 scopus 로고    scopus 로고
    • A peptide competing with VEGF165 binding on neuropilin-1 mediates targeting of a chlorin-type photosensitizer and potentiates its photodynamic activity in human endothelial cells
    • Tirand L., Frochot C., Vanderesse R., Thomas N., Trinquet E., Pinel S., Tirand L., et al. A peptide competing with VEGF165 binding on neuropilin-1 mediates targeting of a chlorin-type photosensitizer and potentiates its photodynamic activity in human endothelial cells. J Control Release 2006, 111:153-164.
    • (2006) J Control Release , vol.111 , pp. 153-164
    • Tirand, L.1    Frochot, C.2    Vanderesse, R.3    Thomas, N.4    Trinquet, E.5    Pinel, S.6    Tirand, L.7
  • 25
    • 34247336893 scopus 로고    scopus 로고
    • Metabolic profile of a peptide-conjugated chlorin-type photosensitizer targeting neuropilin-1: an in vivo and in vitro study
    • Tirand L., Thomas N., Dodeller M., Dumas D., Frochot C., Maunit B., et al. Metabolic profile of a peptide-conjugated chlorin-type photosensitizer targeting neuropilin-1: an in vivo and in vitro study. Drug Metab Dispos 2007, 35:806-813.
    • (2007) Drug Metab Dispos , vol.35 , pp. 806-813
    • Tirand, L.1    Thomas, N.2    Dodeller, M.3    Dumas, D.4    Frochot, C.5    Maunit, B.6
  • 26
    • 41749119863 scopus 로고    scopus 로고
    • Tissue distribution and pharmacokinetics of an ATWLPPR-conjugated chlorin-type photosensitizer targeting neuropilin-1 in glioma-bearing nude mice
    • Thomas N., Tirand L., Chatelut E., Plénat F., Frochot C., Dodeller M., et al. Tissue distribution and pharmacokinetics of an ATWLPPR-conjugated chlorin-type photosensitizer targeting neuropilin-1 in glioma-bearing nude mice. Photochem Photobiol Sci 2008, 7:433-441.
    • (2008) Photochem Photobiol Sci , vol.7 , pp. 433-441
    • Thomas, N.1    Tirand, L.2    Chatelut, E.3    Plénat, F.4    Frochot, C.5    Dodeller, M.6
  • 27
    • 68949104338 scopus 로고    scopus 로고
    • Response surface methodology: an extensive potential to optimize in vivo photodynamic therapy conditions
    • Tirand L., Bastogne T., Bechet D., Linder M., Thomas N., Frochot C., et al. Response surface methodology: an extensive potential to optimize in vivo photodynamic therapy conditions. Int J Radiat Oncol Biol Phys 2009, 75:244-252.
    • (2009) Int J Radiat Oncol Biol Phys , vol.75 , pp. 244-252
    • Tirand, L.1    Bastogne, T.2    Bechet, D.3    Linder, M.4    Thomas, N.5    Frochot, C.6
  • 28
    • 77949266497 scopus 로고    scopus 로고
    • Neuropilin-1 targeting photosensitization-induced early stages of thrombosis via tissue factor release
    • Bechet D., Tirand L., Faivre B., Plénat F., Bonnet C., Bastogne T., et al. Neuropilin-1 targeting photosensitization-induced early stages of thrombosis via tissue factor release. Pharm Res 2010, 27:468-479.
    • (2010) Pharm Res , vol.27 , pp. 468-479
    • Bechet, D.1    Tirand, L.2    Faivre, B.3    Plénat, F.4    Bonnet, C.5    Bastogne, T.6
  • 33
    • 0031779919 scopus 로고    scopus 로고
    • Lymph node staging in non-small-cell lung cancer with FDG-PET scan: a prospective study on 690 lymph node stations from 68 patients
    • Vansteenkiste J.F., Stroobants S.G., De Leyn P.R., Dupont P.J., Bogaert J., Maes A., et al. Lymph node staging in non-small-cell lung cancer with FDG-PET scan: a prospective study on 690 lymph node stations from 68 patients. J Clin Oncol 1998, 16:2142-2149.
    • (1998) J Clin Oncol , vol.16 , pp. 2142-2149
    • Vansteenkiste, J.F.1    Stroobants, S.G.2    De Leyn, P.R.3    Dupont, P.J.4    Bogaert, J.5    Maes, A.6
  • 34
    • 0034131113 scopus 로고    scopus 로고
    • Accuracy and clinical impact of mediastinal lymph node staging with FDG-PET imaging in potentially resectable lung cancer
    • Weng E., Tran L., Rege S., Safa A., Sadeghi A., Juillard G., et al. Accuracy and clinical impact of mediastinal lymph node staging with FDG-PET imaging in potentially resectable lung cancer. Am J Clin Oncol 2000, 23:47-52.
    • (2000) Am J Clin Oncol , vol.23 , pp. 47-52
    • Weng, E.1    Tran, L.2    Rege, S.3    Safa, A.4    Sadeghi, A.5    Juillard, G.6
  • 35
    • 15244354054 scopus 로고    scopus 로고
    • Design, synthesis, and biological evaluation of folic acid targeted tetraphenylporphyrin as novel photosensitizers for selective photodynamic therapy
    • Schneider R., Schmitt F., Frochot C., Fort Y., Lourette N., Guillemin F., et al. Design, synthesis, and biological evaluation of folic acid targeted tetraphenylporphyrin as novel photosensitizers for selective photodynamic therapy. Bioorg Med Chem 2005, 13:2799-2808.
    • (2005) Bioorg Med Chem , vol.13 , pp. 2799-2808
    • Schneider, R.1    Schmitt, F.2    Frochot, C.3    Fort, Y.4    Lourette, N.5    Guillemin, F.6
  • 36
    • 0021675240 scopus 로고
    • New rapid imaging procedure for nuclear spin tomography
    • Hennig J., Nauerth A., Friedburg H., Ratzel D. New rapid imaging procedure for nuclear spin tomography. Radiologe 1984, 24:579-580.
    • (1984) Radiologe , vol.24 , pp. 579-580
    • Hennig, J.1    Nauerth, A.2    Friedburg, H.3    Ratzel, D.4
  • 37
    • 0030725989 scopus 로고    scopus 로고
    • Implementation of quantitative perfusion imaging techniques for functional brain mapping using pulsed arterial spin labeling
    • Wong E.C., Buxton R.B., Frank L.R. Implementation of quantitative perfusion imaging techniques for functional brain mapping using pulsed arterial spin labeling. NMR Biomed 1997, 10:237-249.
    • (1997) NMR Biomed , vol.10 , pp. 237-249
    • Wong, E.C.1    Buxton, R.B.2    Frank, L.R.3
  • 38
    • 0027200329 scopus 로고
    • Automatic, localized in vivo adjustment of all first- and second-order shim coils
    • Gruetter R. Automatic, localized in vivo adjustment of all first- and second-order shim coils. Magn Reson Med 1993, 29:804-811.
    • (1993) Magn Reson Med , vol.29 , pp. 804-811
    • Gruetter, R.1
  • 39
    • 18144399237 scopus 로고    scopus 로고
    • Multifunctional nanoparticle platforms for in vivo MRI enhancement and photodynamic therapy of a rat brain cancer
    • Kopelman R., Koo Y.E.L., Philbert M., Moffat B.A., Reddy G.R., McConville P., et al. Multifunctional nanoparticle platforms for in vivo MRI enhancement and photodynamic therapy of a rat brain cancer. J Magn Magn Mat 2005, 293:404-410.
    • (2005) J Magn Magn Mat , vol.293 , pp. 404-410
    • Kopelman, R.1    Koo, Y.E.L.2    Philbert, M.3    Moffat, B.A.4    Reddy, G.R.5    McConville, P.6
  • 40
    • 7644242772 scopus 로고    scopus 로고
    • Photonic and magnetic nanoexplorers for biomedical use: from subcellular imaging to cancer diagnostics and therapy
    • Ross B., Rehemtulla A., Ko Y.E.L., Reddy R., Kim G., Behrend C., et al. Photonic and magnetic nanoexplorers for biomedical use: from subcellular imaging to cancer diagnostics and therapy. Nanobiophotonics Biomed Appl 2004, 5331:76-83.
    • (2004) Nanobiophotonics Biomed Appl , vol.5331 , pp. 76-83
    • Ross, B.1    Rehemtulla, A.2    Ko, Y.E.L.3    Reddy, R.4    Kim, G.5    Behrend, C.6
  • 41
    • 79955562207 scopus 로고    scopus 로고
    • Targeted photodynamic therapy of breast cancer cells using antibody-phthalocyanine-gold nanoparticle conjugates
    • Stuchinskaya T., Moreno M., Cook M.J., Edwards D.R., Russell D.A. Targeted photodynamic therapy of breast cancer cells using antibody-phthalocyanine-gold nanoparticle conjugates. Photochem Photobiol Sci 2011, 10:822-831.
    • (2011) Photochem Photobiol Sci , vol.10 , pp. 822-831
    • Stuchinskaya, T.1    Moreno, M.2    Cook, M.J.3    Edwards, D.R.4    Russell, D.A.5
  • 42
    • 0037188542 scopus 로고    scopus 로고
    • A fragment of the HMGN2 protein homes to the nuclei of tumor cells and tumor endothelial cells in vivo
    • Porkka K., Laakkonen P., Hoffman J.A., Bernasconi M., Ruoslahti E. A fragment of the HMGN2 protein homes to the nuclei of tumor cells and tumor endothelial cells in vivo. Proc Natl Acad Sci 2002, 99:7444-7449.
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 7444-7449
    • Porkka, K.1    Laakkonen, P.2    Hoffman, J.A.3    Bernasconi, M.4    Ruoslahti, E.5
  • 44
    • 78650731663 scopus 로고    scopus 로고
    • Methylene blue-conjugated hydrogel nanoparticles and tumor-cell targeted photodynamic therapy
    • Hah H.J., Kim G., Lee Y.-E.K., Orringer D.A., Sagher O., Philbert M.A., et al. Methylene blue-conjugated hydrogel nanoparticles and tumor-cell targeted photodynamic therapy. Macromol Biosci 2011, 11:90-99.
    • (2011) Macromol Biosci , vol.11 , pp. 90-99
    • Hah, H.J.1    Kim, G.2    Lee, Y.-E.K.3    Orringer, D.A.4    Sagher, O.5    Philbert, M.A.6
  • 45
    • 79955558399 scopus 로고    scopus 로고
    • Methylene blue covalently loaded polyacrylamide nanoparticles for enhanced tumor-targeted photodynamic therapy
    • Qin M., Hah H.J., Kim G., Nie G., Lee Y.-E.K., Kopelman R. Methylene blue covalently loaded polyacrylamide nanoparticles for enhanced tumor-targeted photodynamic therapy. Photochem Photobiol Sci 2011, 10:832-841.
    • (2011) Photochem Photobiol Sci , vol.10 , pp. 832-841
    • Qin, M.1    Hah, H.J.2    Kim, G.3    Nie, G.4    Lee, Y.-E.K.5    Kopelman, R.6
  • 47
    • 84868693491 scopus 로고    scopus 로고
    • Multifunctional peptide-conjugated hybrid silica nanoparticles for photodynamic therapy and MRI
    • Benachour H., Sève A., Bastogne T., Frochot C., Vanderesse R., Jasniewski J., et al. Multifunctional peptide-conjugated hybrid silica nanoparticles for photodynamic therapy and MRI. Theranostics 2012, 2:889-904.
    • (2012) Theranostics , vol.2 , pp. 889-904
    • Benachour, H.1    Sève, A.2    Bastogne, T.3    Frochot, C.4    Vanderesse, R.5    Jasniewski, J.6
  • 48
    • 0034993240 scopus 로고    scopus 로고
    • The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting
    • Maeda H. The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. Adv Enzyme Regul 2001, 41:189-207.
    • (2001) Adv Enzyme Regul , vol.41 , pp. 189-207
    • Maeda, H.1
  • 49
    • 0034000453 scopus 로고    scopus 로고
    • Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review
    • Maeda H., Wu J., Sawa T., Matsumura Y., Hori K. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J Control Release 2000, 65:271-284.
    • (2000) J Control Release , vol.65 , pp. 271-284
    • Maeda, H.1    Wu, J.2    Sawa, T.3    Matsumura, Y.4    Hori, K.5
  • 50
  • 51
    • 84555220471 scopus 로고    scopus 로고
    • Toward an image-guided microbeam radiation therapy using gadolinium-based nanoparticles
    • Le Duc G., Miladi I., Alric C., Mowat P., Bräuer-Krisch E., Bouchet A., et al. Toward an image-guided microbeam radiation therapy using gadolinium-based nanoparticles. ACS Nano 2011, 5:9566-9574.
    • (2011) ACS Nano , vol.5 , pp. 9566-9574
    • Le Duc, G.1    Miladi, I.2    Alric, C.3    Mowat, P.4    Bräuer-Krisch, E.5    Bouchet, A.6
  • 52
    • 0242496187 scopus 로고    scopus 로고
    • Metabolite changes in BT4C rat gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death as studied by 1H NMR spectroscopy in vivo, ex vivo, and in vitro
    • Lehtimäki K.K., Valonen P.K., Griffin J.L., Väisänen T.H., Gröhn O.H.J., Kettunen M.I., et al. Metabolite changes in BT4C rat gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death as studied by 1H NMR spectroscopy in vivo, ex vivo, and in vitro. J Biol Chem 2003, 278:45915-45923.
    • (2003) J Biol Chem , vol.278 , pp. 45915-45923
    • Lehtimäki, K.K.1    Valonen, P.K.2    Griffin, J.L.3    Väisänen, T.H.4    Gröhn, O.H.J.5    Kettunen, M.I.6
  • 53
    • 0032590214 scopus 로고    scopus 로고
    • 1H MRS detects polyunsaturated fatty acid accumulation during gene therapy of glioma: implications for the in vivo detection of apoptosis
    • Hakumäki J.M., Poptani H., Sandmair A.-M., Ylä-Herttuala S., Kauppinen R.A. 1H MRS detects polyunsaturated fatty acid accumulation during gene therapy of glioma: implications for the in vivo detection of apoptosis. Nat Med 1999, 5:1323-1327.
    • (1999) Nat Med , vol.5 , pp. 1323-1327
    • Hakumäki, J.M.1    Poptani, H.2    Sandmair, A.-M.3    Ylä-Herttuala, S.4    Kauppinen, R.A.5
  • 54
    • 21644467510 scopus 로고    scopus 로고
    • High-resolution magic-angle-spinning 1H NMR spectroscopy reveals different responses in choline-containing metabolites upon gene therapy-induced programmed cell death in rat brain glioma
    • Valonen P.K., Griffin J.L., Lehtimäki K.K., Liimatainen T., Nicholson J.K., Gröhn O.H.J., et al. High-resolution magic-angle-spinning 1H NMR spectroscopy reveals different responses in choline-containing metabolites upon gene therapy-induced programmed cell death in rat brain glioma. NMR Biomed 2005, 18:252-259.
    • (2005) NMR Biomed , vol.18 , pp. 252-259
    • Valonen, P.K.1    Griffin, J.L.2    Lehtimäki, K.K.3    Liimatainen, T.4    Nicholson, J.K.5    Gröhn, O.H.J.6
  • 55
    • 34347350708 scopus 로고    scopus 로고
    • Relationships between gray matter metabolic abnormalities and white matter inflammation in patients at the very early stage of MS: a MRSI study
    • Van Au Duong M., Audoin B., Le Fur Y., Confort-Gouny S., Malikova I., Soulier E., et al. Relationships between gray matter metabolic abnormalities and white matter inflammation in patients at the very early stage of MS: a MRSI study. J Neurol 2007, 254:914-923.
    • (2007) J Neurol , vol.254 , pp. 914-923
    • Van Au Duong, M.1    Audoin, B.2    Le Fur, Y.3    Confort-Gouny, S.4    Malikova, I.5    Soulier, E.6
  • 56
    • 0025105065 scopus 로고
    • Effect of photodynamic therapy on tumor necrosis factor production by murine macrophages
    • Evans S., Matthews W., Perry R., Fraker D., Norton J., Pass H.I. Effect of photodynamic therapy on tumor necrosis factor production by murine macrophages. J Natl Cancer Inst 1990, 82:34-39.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 34-39
    • Evans, S.1    Matthews, W.2    Perry, R.3    Fraker, D.4    Norton, J.5    Pass, H.I.6
  • 57
    • 58349114766 scopus 로고    scopus 로고
    • 5, 6-Dimethylxanthenone-4-acetic acid improves the antitumor efficacy and shortens treatment time associated with Photochlor-sensitized photodynamic therapy
    • Seshadri M., Bellnier D. 5, 6-Dimethylxanthenone-4-acetic acid improves the antitumor efficacy and shortens treatment time associated with Photochlor-sensitized photodynamic therapy. Photochem Photobiol 2009, 85:50-56.
    • (2009) Photochem Photobiol , vol.85 , pp. 50-56
    • Seshadri, M.1    Bellnier, D.2
  • 58
    • 21844455249 scopus 로고    scopus 로고
    • Procoagulant soluble tissue factor is released from endothelial cells in response to inflammatory cytokines
    • Szotowski B., Antoniak S., Poller W., Schultheiss H.P., Rauch U. Procoagulant soluble tissue factor is released from endothelial cells in response to inflammatory cytokines. Circ Res 2005, 96:1233-1239.
    • (2005) Circ Res , vol.96 , pp. 1233-1239
    • Szotowski, B.1    Antoniak, S.2    Poller, W.3    Schultheiss, H.P.4    Rauch, U.5
  • 59
    • 33644548355 scopus 로고    scopus 로고
    • Influence of light fluence rate on the effects of photodynamic therapy in an orthotopic rat glioma model
    • Angell-Petersen E., Spetalen S., Madsen S.J., Sun C.H., Peng Q., Carper S.W., et al. Influence of light fluence rate on the effects of photodynamic therapy in an orthotopic rat glioma model. J Neurosurg 2006, 104:109-117.
    • (2006) J Neurosurg , vol.104 , pp. 109-117
    • Angell-Petersen, E.1    Spetalen, S.2    Madsen, S.J.3    Sun, C.H.4    Peng, Q.5    Carper, S.W.6
  • 60
    • 34247570945 scopus 로고    scopus 로고
    • Determination of fluence rate and temperature distributions in the rat brain; implications for photodynamic therapy
    • Angell-Petersen E., Hirschberg H., Madsen S.J. Determination of fluence rate and temperature distributions in the rat brain; implications for photodynamic therapy. J Biomed Opt 2007, 12:14003.
    • (2007) J Biomed Opt , vol.12 , pp. 14003
    • Angell-Petersen, E.1    Hirschberg, H.2    Madsen, S.J.3
  • 61
    • 0022592172 scopus 로고
    • Rapid NMR imaging of dynamic processes using the FLASH technique
    • Frahm J., Haase A., Matthaei D. Rapid NMR imaging of dynamic processes using the FLASH technique. Magn Reson Med 1986, 3:321-327.
    • (1986) Magn Reson Med , vol.3 , pp. 321-327
    • Frahm, J.1    Haase, A.2    Matthaei, D.3
  • 62
    • 0001437264 scopus 로고
    • Planar spin imaging by NMR
    • Mansfield P., Maudsley A. Planar spin imaging by NMR. J Magn Reson 1977, 27:101-119.
    • (1977) J Magn Reson , vol.27 , pp. 101-119
    • Mansfield, P.1    Maudsley, A.2
  • 63
    • 0031019253 scopus 로고    scopus 로고
    • Perfusion imaging by a flow-sensitive alternating inversion recovery (FAIR) technique: application to functional brain imaging
    • Kim S.G., Tsekos N.V. Perfusion imaging by a flow-sensitive alternating inversion recovery (FAIR) technique: application to functional brain imaging. Magn Reson Med 1997, 37:425-435.
    • (1997) Magn Reson Med , vol.37 , pp. 425-435
    • Kim, S.G.1    Tsekos, N.V.2
  • 64
    • 0023636904 scopus 로고
    • Spatial localization in NMR spectroscopy in vivo
    • Bottomley P.A. Spatial localization in NMR spectroscopy in vivo. Ann N Y Acad Sci 1987, 508:333-348.
    • (1987) Ann N Y Acad Sci , vol.508 , pp. 333-348
    • Bottomley, P.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.