-
1
-
-
0037828315
-
-
Bo L, Vedeler CA, Nyland HI, Trapp BD, Mork SJ (2003) Subpial demyelination in the cerebral cortex of multiple sclerosis patients. J Neuropathol Exp Neurol 62:723-732
-
(2003)
J Neuropathol Exp Neurol
, vol.62
, pp. 723
-
-
Bo1
-
2
-
-
0032935470
-
-
Kidd D, Barkhof F, McConnell R, Algra PR, Allen IV, Revesz T (1999) Cortical lesions in multiple sclerosis. Brain 122:17-26
-
(1999)
Brain
, vol.122
, pp. 17
-
-
Kidd1
-
3
-
-
0002636335
-
-
Lumsden C (1970) The neuropathology of multiple sclerosis, In: Vinken P, Bruyn G, (eds). Handbook of clinical neurology. Amsterdam: North Holland Publishing 9:217-309
-
(1970)
North Holland Publishing
, vol.9
, pp. 217
-
-
Lumsden1
-
4
-
-
0034842126
-
-
Peterson JW, Bo L, Mork S, Chang A, Trapp BD (2001) Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions. Ann Neurol 50:389-400
-
(2001)
Ann Neurol
, vol.50
, pp. 389
-
-
Peterson1
-
5
-
-
0036086983
-
-
Bozzali M, Cercignani M, Sormani MP, Comi G, Filippi M (2002) Quantification of brain gray matter damage in different MS phenotypes by use of diffusion tensor MR imaging. AJNR Am J Neuroradiol 23:985-988
-
(2002)
AJNR Am J Neuroradiol
, vol.23
, pp. 985
-
-
Bozzali1
-
6
-
-
0037273985
-
-
Dehmeshki J, Chard DT, Leary SM, Watt HC, Silver NC, Tofts PS, Thompson AJ, Miller DH (2003) The normal appearing grey matter in primary progressive multiple sclerosis: a magnetisation transfer imaging study. J Neurol 250:67-74
-
(2003)
J Neurol
, vol.250
, pp. 67
-
-
Dehmeshki1
-
7
-
-
0036717266
-
-
Rovaris M, Bozzali B, Iannucci G, Ghezzi A, Caputo D, Montanari E, Bertolotto A, Bergamaschi R, Capra R, Mancardi GL, Martinelli V, Comi G, Filippi M (2002) Assessment of normal- appearing white and gray matter in patients with primary progressive multiple sclerosis: a diffusion-tensor magnetic resonance imaging study. Arch Neurol 59:1406-1412
-
(2002)
Arch Neurol
, vol.59
, pp. 1406
-
-
Rovaris1
-
8
-
-
0037046988
-
-
Traboulsee A, Dehmeshki J, Brex PA, Dalton CM, Chard D, Barker GJ, Plant GT, Miller DH (2002) Normal-appearing brain tissue MTR histograms in clinically isolated syndromes suggestive of MS. Neurology 59:126-128
-
(2002)
Neurology
, vol.59
, pp. 126
-
-
Traboulsee1
-
9
-
-
0035106740
-
-
Ge Y, Grossman R, Udupa JK, Babb JS, Kolson DL, McGowan JC (2001) Magnetization transfer ratio histogram analysis of gray matter in relapsingremitting multiple sclerosis. AJNR Am J Neuroradiol 22:470-475
-
(2001)
AJNR Am J Neuroradiol
, vol.22
, pp. 470
-
-
Ge1
-
10
-
-
0035088438
-
-
Cercignani M, Bozzali M, Iannucci G, Comi G, Filippi M (2001) Magnetisation transfer ratio and mean diffusivity of normal appearing white and grey matter from patients with multiple sclerosis. J Neurol Neurosurg Psychiatry 70:311-317
-
(2001)
J Neurol Neurosurg Psychiatry
, vol.70
, pp. 311
-
-
Cercignani1
-
11
-
-
3042797550
-
-
Davies GR, Ramio-Torrenta L, Hadjiprocopis A, Chard DT, Griffin CM, Rashid W, Barker GJ, Kapoor R, Thompson AJ, Miller DH (2004) Evidence for grey matter MTR abnormality in minimally disabled patients with early relapsing-remitting multiple sclerosis. J Neurol Neurosurg Psychiatry 75:998-1002
-
(2004)
J Neurol Neurosurg Psychiatry
, vol.75
, pp. 998
-
-
Davies1
-
12
-
-
0037426402
-
-
De Stefano N, Matthews P, Filippi M, Agosta F, De Luca M, Bartolozzi M, Guidi L, Ghezzi A, Montanari E, Cifelli A, Federico A, Smith SM (2003) Evidence of early cortical atrophy in MS: relevance to white matter changes and disability. Neurology 60:1157-1162
-
(2003)
Neurology
, vol.60
, pp. 1157
-
-
De Stefano1
-
13
-
-
0036788493
-
-
Chard DT, Griffin CM, McLean MA, Kapeller P, Kapoor RT, AJ, Miller DH (2002) Brain metabolite changes in cortical grey and normal-appearing white matter in clinically early relapsing- remitting multiple sclerosis. Brain 125:2342-2352
-
(2002)
Brain
, vol.125
, pp. 2342
-
-
Chard1
-
14
-
-
0036161001
-
-
Chard DT, Griffin CM, Barker GJ, Kapoor R, Thompson AJ, Miller DH (2002) Brain atrophy in clinically early relapsing-remitting multiple sclerosis. Brain 125:327-337
-
(2002)
Brain
, vol.125
, pp. 327
-
-
Chard1
-
15
-
-
0035989123
-
-
Griffin CM, Dehmeshki J, Chard DT, Parker GJ, Barker GJ, Thompson AJ, Miller DH (2002) T1 histograms of normal-appearing brain tissue are abnormal in early relapsing-remitting multiple sclerosis. Mult Scler 8:211-216
-
(2002)
Mult Scler
, vol.8
, pp. 211
-
-
Griffin1
-
16
-
-
0034121184
-
-
Iannucci G, Tortorella C, Rovaris M, Sormani MP, Comi G, Filippi M (2000) Prognostic value of MR and magnetization transfer imaging findings in patients with clinically isolated syndromes suggestive of multiple sclerosis at presentation. AJNR Am J Neuroradiol 21:1034-1038
-
(2000)
AJNR Am J Neuroradiol
, vol.21
, pp. 1034
-
-
Iannucci1
-
17
-
-
7044262267
-
-
Audoin B, Ranjeva JP, Au Duong MV, Ibarrola D, Malikova I, Confort-Gouny S, Soulier E, Viout P, Ali-Cherif A, Pelletier J, Cozzone PJ (2004) Voxelbased analysis of MTR images: a method to locate gray matter abnormalities in patients at the earliest stage of multiple sclerosis. J Magn Reson Imaging 20:765-771
-
(2004)
J Magn Reson Imaging
, vol.20
, pp. 765
-
-
Audoin1
-
18
-
-
0035077346
-
-
Kapeller P, McLean MA, Griffin CM, Chard D, Parker GJ, Barker GJ, Thompson AJ, Miller DH (2001) Preliminary evidence for neuronal damage in cortical grey matter and normal appearing white matter in short duration relapsing-remitting multiple sclerosis: a quantitative MR spectroscopic imaging study. J Neurol 248:131-138
-
(2001)
J Neurol
, vol.248
, pp. 131
-
-
Kapeller1
-
19
-
-
0034892303
-
-
Sharma R, Narayana PA, Wolinsky JS (2001) Grey matter abnormalities in multiple sclerosis: proton magnetic resonance spectroscopic imaging. Mult Scler 7:221-226
-
(2001)
Mult Scler
, vol.7
, pp. 221
-
-
Sharma1
-
20
-
-
0036310111
-
-
Sarchielli P, Presciutti O, Tarducci R, Gobbi G, Alberti A, Pelliccioli GP, Chiarini P, Gallai V (2002) Localized (1)H magnetic resonance spectroscopy in mainly cortical gray matter of patients with multiple sclerosis. J Neurol 249:902-910
-
(2002)
J Neurol
, vol.249
, pp. 902
-
-
Sarchielli1
-
21
-
-
0344392030
-
-
Adalsteinsson E, Langer-Gould A, Homer RJ, Rao A, Sullivan EV, Lima CA, Pfefferbaum A, Atlas SW (2003) Gray matter N-acetyl aspartate deficits in secondary progressive but not relapsing-remitting multiple sclerosis. AJNR Am J Neuroradiol 24:1941-1945
-
(2003)
AJNR Am J Neuroradiol
, vol.24
, pp. 1941
-
-
Adalsteinsson1
-
22
-
-
0034880410
-
-
Galanaud D, Le Fur Y, Nicoli F, Denis B, Confort-Gouny S, Ranjeva JP, Viout P, Pelletier J, Cozzone PJ (2001) Regional metabolite levels of the normal posterior fossa studied by proton chemical shift imaging. Magma 13:127-133
-
(2001)
Magma
, vol.13
, pp. 127
-
-
Galanaud1
-
23
-
-
18744434897
-
-
Nicoli F, Lefur Y, Denis B, Ranjeva JP, Confort-Gouny S, Cozzone PJ (2003) Metabolic counterpart of decreased apparent diffusion coefficient during hyperacute ischemic stroke: a brain proton magnetic resonance spectroscopic imaging study. Stroke 34:e82-e87
-
(2003)
Stroke
, vol.34
, pp. 82
-
-
Nicoli1
-
24
-
-
0344796399
-
-
Ranjeva JP, Pelletier J, Confort-Gouny S, Ibarrola D, Audoin B, Le Fur Y, Viout P, Cherif AA, Cozzone PJ (2003) MRI/MRS of corpus callosum in patients with clinically isolated syndrome suggestive of multiple sclerosis. Mult Scler 9:554-565
-
(2003)
Mult Scler
, vol.9
, pp. 554
-
-
Ranjeva1
-
25
-
-
0028081569
-
-
Matson GB (1994) An integrated program for amplitude-modulated RF pulse generation and re-mapping with shaped gradients. Magn Reson Imaging 12:1205-1225
-
(1994)
Magn Reson Imaging
, vol.12
, pp. 1205
-
-
Matson1
-
26
-
-
0033979021
-
-
von Kienlin M, Ziegler A, Le Fur Y, Rubin C, Decorps M, Remy C (2000) 2D-spatial/2D-spectral spectroscopic imaging of intracerebral gliomas in rat brain. Magn Reson Med 43:211-219
-
(2000)
Magn Reson Med
, vol.43
, pp. 211
-
-
Von Kienlin1
-
27
-
-
0032588957
-
-
Tkac I, Starcuk Z, Choi IY, Gruetter R (1999) In vivo 1H NMR spectroscopy of rat brain at 1 ms echo time. Magn Reson Med 41:649-656
-
(1999)
Magn Reson Med
, vol.41
, pp. 649
-
-
Tkac1
-
28
-
-
0036799124
-
-
Guye M, Le Fur Y, Confort-Gouny S, Ranjeva JP, Bartolomei F, Regis J, Raybaud CA, Chauvel P, Cozzone PJ (2002) Metabolic and electrophysiological alterations in subtypes of temporal lobe epilepsy: a combined proton magnetic resonance spectroscopic imaging and depth electrodes study. Epilepsia 43:1197-1209
-
(2002)
Epilepsia
, vol.43
, pp. 1197
-
-
Guye1
-
29
-
-
0037306784
-
-
Galanaud D, Chinot O, Nicoli F, Confort-Gouny S, Le Fur Y, Barrie-Attarian M, Ranjeva JP, Fuentes S, Viout P, Figarella-Branger D, Cozzone PJ (2003) Use of proton magnetic resonance spectroscopy of the brain to differentiate gliomatosis cerebri from low-grade glioma. J Neurosurg 98:269-276
-
(2003)
J Neurosurg
, vol.98
, pp. 269
-
-
Galanaud1
-
30
-
-
6344287785
-
-
Viola A, Nicoli F, Denis B, Confort-Gouny S, Le Fur Y, Ranjeva JP, Viout P, Cozzone PJ (2004) High cerebral scyllo-inositol: a new marker of brain metabolism disturbances induced by chronic alcoholism. Magma 17:47- 61
-
(2004)
Magma
, vol.17
, pp. 47
-
-
Viola1
-
31
-
-
0035742198
-
-
Cabanes E, Confort-Gouny S, Le Fur Y, Simond G, Cozzone PJ (2001) Optimization of residual water signal removal by HLSVD on simulated short echo time proton MR spectra of the human brain. J Magn Reson 150:116-125
-
(2001)
J Magn Reson
, vol.150
, pp. 116
-
-
Cabanes1
-
32
-
-
0036338657
-
-
Weber-Fahr W, Ende G, Braus DF, Bachert P, Soher BJ, Henn FA, Buchel C (2002) A fully automated method for tissue segmentation and CSF-correction of proton MRSI metabolites corroborates abnormal hippocampal NAA in schizophrenia. Neuroimage 16:49-60
-
(2002)
Neuroimage
, vol.16
, pp. 49
-
-
Weber-Fahr1
-
33
-
-
18744384369
-
-
Ranjeva JP, Audoin B, Au Duong MV, Ibarrola D, Confort-Gouny S, Malikova I, Soulier E, Viout P, Ali-Cherif A, Pelletier J, Cozzone P (2005) Local tissue damage assessed with statistical mapping analysis of brain magnetization transfer ratio: relationship with functional status of patients in the earliest stage of multiple sclerosis. AJNR Am J Neuroradiol 26:119-127
-
(2005)
AJNR Am J Neuroradiol
, vol.26
, pp. 119
-
-
Ranjeva1
-
34
-
-
0034038644
-
-
Gareau PJ, Rutt BK, Karlik SJ, Mitchell JR (2000) Magnetization transfer and multicomponent T2 relaxation measurements with histopathologic correlation in an experimental model of MS. J Magn Reson Imaging 11:586-595
-
(2000)
J Magn Reson Imaging
, vol.11
, pp. 586
-
-
Gareau1
-
35
-
-
4444310685
-
-
Schmierer K, Scaravilli F, Altmann DR, Barker GJ, Miller DH (2004) Magnetization transfer ratio and myelin in postmortem multiple sclerosis brain. Ann Neurol 56:407-415
-
(2004)
Ann Neurol
, vol.56
, pp. 407
-
-
Schmierer1
-
36
-
-
0033595484
-
-
van Waesberghe JH, Barkhof F (1999) Magnetization transfer imaging of the spinal cord and the optic nerve in patients with multiple sclerosis. Neurology 53:S46-S48
-
(1999)
Neurology
, vol.53
, pp. 46
-
-
Waesberghe, V.1
-
37
-
-
0033563766
-
-
Brex PA, Gomez-Anson B, Parker GJ, Molyneux PD, Miszkiel KA, Barker GJ, MacManus DG, Davie CA, Plant GT, Miller DH (1999) Proton MR spectroscopy in clinically isolated syndromes suggestive of multiple sclerosis. J Neurol Sci 166:16-22
-
(1999)
J Neurol Sci
, vol.166
, pp. 16
-
-
Brex1
-
38
-
-
2942627700
-
-
Fernando KT, McLean MA, Chard DT, MacManus DG, Dalton CM, Miszkiel KA, Gordon RM, Plant GT, Thompson AJ, Miller DH (2004) Elevated white matter myo-inositol in clinically isolated syndromes suggestive of multiple sclerosis. Brain 127:1361-1369
-
(2004)
Brain
, vol.127
, pp. 1361
-
-
Fernando1
-
39
-
-
0037312536
-
-
Filippi M, Bozzali M, Rovaris M, Gonen O, Kesavadas C, Ghezzi A, Martinelli V, Grossman RI, Scotti G, Comi G, Falini A (2003) Evidence for widespread axonal damage at the earliest clinical stage of multiple sclerosis. Brain 126:433-437
-
(2003)
Brain
, vol.126
, pp. 433
-
-
Filippi1
-
40
-
-
0032852674
-
-
De Stefano N, Narayanan S, Matthews PM, Francis GS, Antel JP, Arnold DL (1999) In vivo evidence for axonal dysfunction remote from focal cerebral demyelination of the type seen in multiple sclerosis. Brain 122:1933-1939
-
(1999)
Brain
, vol.122
, pp. 1933
-
-
De Stefano1
-
41
-
-
0028265609
-
-
Davie CA, Hawkins CP, Barker GJ, Brennan A, Tofts PS, Miller DH, McDonald WI (1994) Serial proton magnetic resonance spectroscopy in acute multiple sclerosis lesions. Brain 117:49-58
-
(1994)
Brain
, vol.117
, pp. 49
-
-
Davie1
-
42
-
-
0026531884
-
-
Arnold DL, Matthews PM, Francis GS, O'Connor J, Antel JP (1992) Proton magnetic resonance spectroscopic imaging for metabolic characterization of demyelinating plaques. Ann Neurol 31:235-241
-
(1992)
Ann Neurol
, vol.31
, pp. 235
-
-
Arnold1
-
43
-
-
0029609682
-
-
De Stefano N, Matthews PM, Antel JP, Preul M, Francis G, Arnold DL (1995) Chemical pathology of acute demyelinating lesions and its correlation with disability. Ann Neurol 38:901-909
-
(1995)
Ann Neurol
, vol.38
, pp. 901
-
-
De Stefano1
-
44
-
-
0031891884
-
-
Narayana PA, Doyle TJ, Lai D, Wolinsky JS (1998) Serial proton magnetic resonance spectroscopic imaging, contrast-enhanced magnetic resonance imaging, and quantitative lesion volumetry in multiple sclerosis. Ann Neurol 43:56-71
-
(1998)
Ann Neurol
, vol.43
, pp. 56
-
-
Narayana1
-
45
-
-
0036894999
-
-
Knowlton RC, Abou-Khalil B, Sawrie SM, Martin RC, Faught RE, Kuzniecky RI (2002) In vivo hippocampal metabolic dysfunction in human temporal lobe epilepsy. Arch Neurol 59:1882-1886
-
(2002)
Arch Neurol
, vol.59
, pp. 1882
-
-
Knowlton1
-
46
-
-
1842557960
-
-
Knowlton RC (2004) Multimodality imaging in partial epilepsies. Curr Opin Neurol 17:165-172
-
(2004)
Curr Opin Neurol
, vol.17
, pp. 165
-
-
Knowlton1
-
47
-
-
0038813918
-
-
Petroff OA, Errante LD, Kim JH, Spencer DD (2003) N-acetyl-aspartate, total creatine, and myo-inositol in the epileptogenic human hippocampus. Neurology 60:1646-1651
-
(2003)
Neurology
, vol.60
, pp. 1646
-
-
Petroff1
-
48
-
-
1642504396
-
-
Vielhaber S, Kudin AP, Kudina TA, Stiller D, Scheich H, Schoenfeld A, Feistner H, Heinze HJ, Elger CE, Kunz WS (2003) Hippocampal N-acetyl aspartate levels do not mirror neuronal cell densities in creatine-supplemented epileptic rats. Eur J Neurosci 18:2292- 2300
-
(2003)
Eur J Neurosci
, vol.18
, pp. 2292
-
-
Vielhaber1
-
49
-
-
0035788425
-
-
Narayanan S, De Stefano N, Francis GS, Arnaoutelis R, Caramanos Z, Collins DL, Pelletier D, Arnason BGW, Antel JP, Arnold DL (2001) Axonal metabolic recovery in multiple sclerosis patients treated with interferon beta-1b. J Neurol 248:979-986
-
(2001)
J Neurol
, vol.248
, pp. 979
-
-
Narayanan1
-
50
-
-
0033842931
-
-
Mader I, Roser W, Kappos L, Hagberg G, Seelig J, Radue EW, Steinbrich W (2000) Serial proton MR spectroscopy of contrast-enhancing multiple sclerosis plaques: absolute metabolic values over 2 years during a clinical pharmacological study. AJNR Am J Neuroradiol 21:1220-1227
-
(2000)
AJNR Am J Neuroradiol
, vol.21
, pp. 1220
-
-
Mader1
-
51
-
-
0035049083
-
-
Demougeot C, Garnier P, Mossiat C, Bertrand N, Giroud M, Beley A, Marie C (2001) N-Acetylaspartate, a marker of both cellular dysfunction and neuronal loss: its relevance to studies of acute brain injury. J Neurochem 77:408-415
-
(2001)
J Neurochem
, vol.77
, pp. 408
-
-
Demougeot1
-
52
-
-
0035871761
-
-
Ross B, Bluml S (2001) Magnetic resonance spectroscopy of the human brain. Anat Rec 265:54-84
-
(2001)
Anat Rec
, vol.265
, pp. 54
-
-
Ross1
-
53
-
-
0033624030
-
-
Suhy J, Rooney WD, Goodkin DE, Capizzano AA, Soher BJ, Maudsley AA, Waubant E, Andersson PB, Weiner MW (2000) 1H MRSI comparison of white matter and lesions in primary progressive and relapsingremitting MS. Mult Scler 6:148-155
-
(2000)
Mult Scler
, vol.6
, pp. 148
-
-
Suhy1
-
54
-
-
12844251990
-
-
Vrenken H, Barkhof F, Uitdehaag BM, Castelijns JA, Polman CH, Pouwels PJ (2005) MR spectroscopic evidence for glial increase but not for neuro-axonal damage in MS normal-appearing white matter. Magn Reson Med 53:256-266
-
(2005)
Magn Reson Med
, vol.53
, pp. 256
-
-
Vrenken1
-
55
-
-
0035990034
-
-
Kapeller P, Brex PA, Chard D, Dalton C, Griffin CM, McLean MA, Parker GJ, Thompson AJ, Miller DH (2002) Quantitative 1H MRS imaging 14 years after presenting with a clinically isolated syndrome suggestive of multiple sclerosis. Mult Scler 8:207-210
-
(2002)
Mult Scler
, vol.8
, pp. 207
-
-
Kapeller1
-
56
-
-
0029665218
-
-
Miller BL, Chang L, Booth R, Ernst T, Cornford M, Nikas D, McBride D, Jenden DJ (1996) In vivo 1H MRS choline: correlation with in vitro chemistry/histology. Life Sci 58:1929-1935
-
(1996)
Life Sci
, vol.58
, pp. 1929
-
-
Miller1
-
57
-
-
1442323745
-
-
Ross AJ, Sachdev PS (2004) Magnetic resonance spectroscopy in cognitive research. Brain Res Brain Res Rev 44:83-102
-
(2004)
Brain Res Brain Res Rev
, vol.44
, pp. 83
-
-
Ross1
-
58
-
-
0027265195
-
-
Brenner RE, Munro PM, Williams SC, Bell JD, Barker GJ, Hawkins CP, Landon DN, McDonald WI (1993) The proton NMR spectrum in acute EAE: the significance of the change in the Cho:Cr ratio. Magn Reson Med 29:737-745
-
(1993)
Magn Reson Med
, vol.29
, pp. 737
-
-
Brenner1
|