Neuropilin-1 targeting photosensitization-induced early stages of thrombosis via tissue factor release

Pharmaceutical Research

Volumn 27, Issue 3, 2010, Pages 468-479

  Bechet, Denise ^a   Tirand, Loraine ^a   Faivre, Béatrice ^b   Plénat, François ^b   Bonnet, Corinne ^b   Bastogne, Thierry ^a,c   Frochot, Céline ^b,c   Guillemin, François ^a,c   Barberi Heyob, Muriel ^a,c  

^a CENTRE DE RECHERCHE EN AUTOMATIQUE DE NANCY   (France)

^b UNIVERSITÉ DE LORRAINE   (France)

^c GDR   (France)

Author keywords

Blood flow; Endothelial cells; Neuropilin 1; Thrombogenic effect; Tissue factor

Indexed keywords

5 (4 CARBOXYPHENYL) 10,15,20 TRIPHENYLCHLORIN 6 AMINOHEXANOIC ACID HYDROXYALANYLTHREONYLTRYPTOPHYLLEUCYLPROLYLPROLYLARGININE CONJUGATE; FIBRINOGEN; HEPTAPEPTIDE; NEUROPILIN 1; PHOTOSENSITIZING AGENT; THROMBOPLASTIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DRUG CONJUGATION; DRUG EFFECT; DRUG EFFICACY; ENDOTHELIUM CELL; FEMALE; GLIOMA; MOUSE; NONHUMAN; NUDE MOUSE; PHOTODYNAMIC THERAPY; PHOTOSENSITIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; THROMBOGENESIS; THROMBOSIS; TREATMENT OUTCOME; TUMOR BLOOD FLOW;

ANIMALS; BLOOD VESSELS; ENDOTHELIAL CELLS; FEMALE; GLIOMA; HUMANS; MICE; MICE, NUDE; NEUROPILIN-1; OLIGOPEPTIDES; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PORPHYRINS; THROMBOPLASTIN; THROMBOSIS;

EID: 77949266497     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-009-0035-8     Document Type: Article

References (49)

1. J Folkman 1995 Angiogenesis in cancer, vascular, rheumatoid and other disease Nat Med 1 27 31 10.1038/nm0195-27 7584949 1:CAS:528:DyaK2MXjs1KnsLk%3D
2. TJ Dougherty CJ Gomer BW Henderson G Jori D Kessel M Korbelik, et al. 1998 Photodynamic therapy J Natl Cancer Inst 90 889 905 10.1093/jnci/90.12.889 9637138 1:CAS:528:DyaK1cXktFOqsLY%3D (Pubitemid 28304157)
3. K Ichikawa T Hikita N Maeda S Yonezawa Y Takeuchi T Asai, et al. 2005 Antiangiogenic photodynamic therapy (PDT) by using long-circulating liposomes modified with peptide specific to angiogenic vessels Biochim Biophys Acta 1669 69 74 10.1016/j.bbamem.2005.02.003 15843001 1:CAS:528:DC%2BD2MXjsVGlu7g%3D (Pubitemid 40544523)
4. B Chen BW Pogue JM Luna RL Hardman PJ Hoopes T Hasan 2006 Tumor vascular permeabilization by vascular-targeting photosensitization: effects, mechanism, and therapeutic implications Clin Cancer Res 12 917 923 10.1158/1078-0432.CCR- 05-1673 16467106 1:CAS:528:DC%2BD28XhtFeiu7g%3D (Pubitemid 43259874)
5. VH Fingar SW Taber PS Haydon LT Harrison SJ Kempf TJ Wieman 2000 Vascular damage after photodynamic therapy of solid tumors: a view and comparison of effect in pre-clinical and clinical models at the University of Louisville In Vivo 14 93 100 10757064 1:STN:280:DC%2BD3c3itVGlsQ%3D%3D
6. Z Huang Q Chen D Luck J Beckers BC Wilson N Trncic, et al. 2005 Studies of a vascular-acting photosensitizer, Pd-bacteriopheophorbide (Tookad), in normal canine prostate and spontaneous canine prostate cancer Lasers Surg Med 36 390 397 10.1002/lsm.20177 15856509 1:CAS:528:DC%2BD2MXhtlWksbbJ (Pubitemid 40942154)
7. KS McMahon TJ Wieman PH Moore VH Fingar 1994 Effects of photodynamic therapy using mono-L-aspartyl chlorin e6 on vessel constriction, vessel leakage, and tumor response Cancer Res 54 5374 5379 7923168 1:CAS:528:DyaK2cXmsV2ktLo%3D
8. TJ Wieman TS Mang VH Fingar TG Hill MW Reed TS Corey, et al. 1988 Effect of photodynamic therapy on blood flow in normal and tumor vessels Surgery 104 512 517 2970687 1:STN:280:DyaL1czit1SmtQ%3D%3D
9. VH Fingar TJ Wieman SA Wiehle PB Cerrito 1992 The role of microvascular damage in photodynamic therapy: the effect of treatment on vessel constriction, permeability, and leukocyte adhesion Cancer Res 52 4914 4921 1387584 1:CAS:528:DyaK38XlvVOnsL8%3D
10. VH Fingar 1996 Vascular effects of photodynamic therapy J Clin Laser Med Surg 14 323 328 9612199 1:STN:280:DyaK1c3nsFWntA%3D%3D
11. BW Henderson TJ Dougherty 1992 How does photodynamic therapy work? Photochem Photobiol 55 145 157 10.1111/j.1751-1097.1992.tb04222.x 1603846 1:CAS:528:DyaK38XnvFCiuw%3D%3D
12. K Kurohane A Tominaga K Sato JR North Y Namba N Oku 2001 Photodynamic therapy targeted to tumor-induced angiogenic vessels Cancer Lett 167 49 56 10.1016/S0304-3835(01)00475-X 11323098 1:CAS:528:DC%2BD3MXivFeiuro%3D (Pubitemid 32373268)
13. B Chen BW Pogue PJ Hoopes T Hasan 2006 Vascular and cellular targeting for photodynamic therapy Crit Rev Eukaryot Gene Expr 16 279 305 17206921
14. A Starzec P Ladam R Vassy S Badache N Bouchemal A Navaza, et al. 2007 Structure-function analysis of the antiangiogenic ATWLPPR peptide inhibiting VEGF(165) binding to neuropilin-1 and molecular dynamics simulations of the ATWLPPR/neuropilin-1 complex Peptides 28 2397 2402 10.1016/j.peptides.2007.09. 013 17983687 1:CAS:528:DC%2BD2sXhtlCqsrnN (Pubitemid 350116304)
15. L Tirand C Frochot R Vanderesse N Thomas E Trinquet S Pinel, et al. 2006 A peptide competing with VEGF165 binding on neuropilin-1 mediates targeting of a chlorin-type photosensitizer and potentiates its photodynamic activity in human endothelial cells J Control Release 111 153 164 10.1016/j.jconrel.2005.11.017 16423422 1:CAS:528:DC%2BD28XhslKjtrk%3D (Pubitemid 43290004)
16. Thomas N, Bechet D, Becuwe P, Tirand L, Vanderesse R, Frochot C, et al. Peptide-conjugated chlorin-type photosensitizer binds neuropilin-1 in vitro and in vivo. J Photochem Photobiol B. 2009;96:101-8.
17. N Thomas L Tirand E Chatelut F Plenat C Frochot M Dodeller, et al. 2008 Tissue distribution and pharmacokinetics of an ATWLPPR-conjugated chlorin-type photosensitizer targeting neuropilin-1 in glioma-bearing nude mice Photochem Photobiol Sci 7 433 441 10.1039/b718259g 18385885 1:CAS:528:DC%2BD1cXkt1Sku7Y%3D
18. Tirand L, Bastogne T, Bechet D, Linder M, Thomas N, Frochot C, et al. Response surface methodology: an extensive potential to optimize in vivo photodynamic therapy conditions. Int J Radiat Oncol Biol Phys. 2009;75:244-52.
19. L Tirand N Thomas M Dodeller D Dumas C Frochot B Maunit, et al. 2007 Metabolic profile of a peptide-conjugated chlorin-type photosensitizer targeting neuropilin-1: an in vivo and in vitro study Drug Metab Dispos 35 806 813 10.1124/dmd.106.013763 17283031 1:CAS:528:DC%2BD2sXlsVWmur8%3D (Pubitemid 46641552)
20. S Pinel M Barberi-Heyob E Cohen-Jonathan JL Merlin C Delmas F Plenat, et al. 2004 Erythropoietin-induced reduction of hypoxia before and during fractionated irradiation contributes to improvement of radioresponse in human glioma xenografts Int J Radiat Oncol Biol Phys 59 250 259 15093922 1:CAS:528:DC%2BD2cXjt1SisbY%3D
21. F Chergui AS Chretien S Bouali C Ramacci M Rouyer T Bastogne, et al. 2009 Validation of a phosphoprotein array assay for characterization of human tyrosine kinase receptor downstream signaling in breast cancer Clin Chem 55 1327 1336 10.1373/clinchem.2008.116632 19443568 1:CAS:528:DC%2BD1MXotFantbc%3D
22. G Yu T Durduran C Zhou HW Wang ME Putt HM Saunders, et al. 2005 Noninvasive monitoring of murine tumor blood flow during and after photodynamic therapy provides early assessment of therapeutic efficacy Clin Cancer Res 11 3543 3552 10.1158/1078-0432.CCR-04-2582 15867258 1:CAS:528:DC%2BD2MXjslOqtb8%3D (Pubitemid 40627910)
23. DK Kelleher O Thews A Scherz Y Salomon P Vaupel 2004 Perfusion, oxygenation status and growth of experimental tumors upon photodynamic therapy with Pd-bacteriopheophorbide Int J Oncol 24 1505 1511 15138594 1:CAS:528:DC%2BD2cXkvFaisL4%3D
24. TE Dudar RK Jain 1984 Differential response of normal and tumor microcirculation to hyperthermia Cancer Res 44 605 612 6692365 1:STN:280:DyaL2c7gs1GjsA%3D%3D
25. N Mackman 1995 Regulation of the tissue factor gene Faseb J 9 883 889 7615158 1:CAS:528:DyaK2MXntFyrsLY%3D
26. G Archipoff A Beretz JM Freyssinet C Klein-Soyer C Brisson JP Cazenave 1991 Heterogeneous regulation of constitutive thrombomodulin or inducible tissue-factor activities on the surface of human saphenous-vein endothelial cells in culture following stimulation by interleukin-1, tumour necrosis factor, thrombin or phorbol ester Biochem J 273 Pt 3 679 684 1847620 1:CAS:528:DyaK3MXnvFanuw%3D%3D
27. DW Siemann DJ Chaplin MR Horsman 2004 Vascular-targeting therapies for treatment of malignant disease Cancer 100 2491 2499 10.1002/cncr.20299 15197790 1:CAS:528:DC%2BD2cXlsFChsrY%3D (Pubitemid 38715753)
28. RA Brekken C Li S Kumar 2002 Strategies for vascular targeting in tumors Int J Cancer 100 123 130 10.1002/ijc.10462 12115558 1:CAS:528: DC%2BD38XkvFygurY%3D (Pubitemid 34666183)
29. DE Dolmans A Kadambi JS Hill CA Waters BC Robinson JP Walker, et al. 2002 Vascular accumulation of a novel photosensitizer, MV6401, causes selective thrombosis in tumor vessels after photodynamic therapy Cancer Res 62 2151 2156 11929837 1:CAS:528:DC%2BD38XivVylu7Y%3D
30. ME Eichhorn S Strieth M Dellian 2004 Anti-vascular tumor therapy: recent advances, pitfalls and clinical perspectives Drug Resist Updat 7 125 138 10.1016/j.drup.2004.03.001 15158768 1:CAS:528:DC%2BD2cXkt1WqurY%3D (Pubitemid 38736065)
31. PE Thorpe DJ Chaplin DC Blakey 2003 The first international conference on vascular targeting: meeting overview Cancer Res 63 1144 1147 12615734 1:CAS:528:DC%2BD3sXhs1agtLY%3D
32. JM Ebos CR Lee W Cruz-Munoz GA Bjarnason JG Christensen RS Kerbel 2009 Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis Cancer Cell 15 232 239 10.1016/j.ccr.2009.01.021 19249681 1:CAS:528:DC%2BD1MXltFSmtbc%3D
33. M Klagsbrun S Takashima R Mamluk 2002 The role of neuropilin in vascular and tumor biology Adv Exp Med Biol 515 33 48 12613541 1:CAS:528: DC%2BD3sXisl2jsLw%3D
34. RM Leach HS Hill VA Snetkov JP Ward 2002 Hypoxia, energy state and pulmonary vasomotor tone Respir Physiol Neurobiol 132 55 67 10.1016/S1569- 9048(02)00049-6 12126695 1:CAS:528:DC%2BD38XntVKjtb0%3D (Pubitemid 34765689)
35. SC Lin CP Lin JR Feld JS Duker CA Puliafito 1994 The photodynamic occlusion of choroidal vessels using benzoporphyrin derivative Curr Eye Res 13 513 522 10.3109/02713689408999883 7523029 1:CAS:528:DyaK2cXmsVOltb8%3D
36. VH Fingar PK Kik PS Haydon PB Cerrito M Tseng E Abang, et al. 1999 Analysis of acute vascular damage after photodynamic therapy using benzoporphyrin derivative (BPD) Br J Cancer 79 1702 1708 10.1038/sj.bjc.6690271 10206280 1:CAS:528:DyaK1MXisVKlsLg%3D
37. KK Wu P Thiagarajan 1996 Role of endothelium in thrombosis and hemostasis Annu Rev Med 47 315 331 10.1146/annurev.med.47.1.315 8712785 1:CAS:528:DyaK28XitlSntL4%3D (Pubitemid 26138894)
38. P Fungaloi P Waterman G Nigri R Statius-van Eps W Sluiter H van Urk, et al. 2003 Photochemically modulated endothelial cell thrombogenicity via the thrombomodulin-tissue factor pathways Photochem Photobiol 78 475 480 10.1562/0031-8655(2003)078<0475:PMECTV>2.0.CO;2 14653579 1:CAS:528:DC%2BD3sXptFOjtb8%3D
39. H Wada Y Wakita H Shiku 1995 Tissue factor expression in endothelial cells in health and disease Blood Coagul Fibrinolysis 6 Suppl 1 S26 S31 10.1097/00001721-199506001-00005 7647217 1:CAS:528:DyaK2MXnslSktLs%3D
40. A Zillmann T Luther I Muller M Kotzsch M Spannagl T Kauke, et al. 2001 Platelet-associated tissue factor contributes to the collagen-triggered activation of blood coagulation Biochem Biophys Res Commun 281 603 609 10.1006/bbrc.2001.4399 11181090 1:CAS:528:DC%2BD3MXht1ahsro%3D (Pubitemid 32928197)
41. T Bombeli A Karsan JF Tait JM Harlan 1997 Apoptotic vascular endothelial cells become procoagulant Blood 89 2429 2442 9116287 1:CAS:528: DyaK2sXitVyisrk%3D
42. P Fungaloi R Statius van Eps YP Wu J Blankensteijn P de Groot H van Urk, et al. 2002 Platelet adhesion to photodynamic therapy-treated extracellular matrix proteins Photochem Photobiol 75 412 417 10.1562/0031-8655(2002) 075<0412:PATPTT>2.0.CO;2 12003132 1:CAS:528:DC%2BD38Xjt1altbs%3D
43. HM Liu DL Wang CY Liu 1990 Interactions between fibrin, collagen and endothelial cells in angiogenesis Adv Exp Med Biol 281 319 331 1715120 1:CAS:528:DyaK3MXlsFKgtrs%3D
44. ME Daly A Makris M Reed CE Lewis 2003 Hemostatic regulators of tumor angiogenesis: a source of antiangiogenic agents for cancer treatment? J Natl Cancer Inst 95 1660 1673 14625257 1:CAS:528:DC%2BD3sXptlyktr0%3D
45. S Evans W Matthews R Perry D Fraker J Norton HI Pass 1990 Effect of photodynamic therapy on tumor necrosis factor production by murine macrophages J Natl Cancer Inst 82 34 39 10.1093/jnci/82.1.34 2293654 1:STN:280: DyaK3c%2FnvF2qtQ%3D%3D
46. M Seshadri DA Bellnier 2009 The vascular disrupting agent 5, 6-dimethylxanthenone-4-acetic acid improves the antitumor efficacy and shortens treatment time associated with Photochlor-sensitized photodynamic therapy in vivo Photochem Photobiol 85 50 56 10.1111/j.1751-1097.2008.00395.x 18643909 1:CAS:528:DC%2BD1MXislamsrw%3D
47. B Szotowski S Antoniak W Poller HP Schultheiss U Rauch 2005 Procoagulant soluble tissue factor is released from endothelial cells in response to inflammatory cytokines Circ Res 96 1233 1239 10.1161/01.RES.0000171805.24799.fa 15920023 1:CAS:528:DC%2BD2MXltlSjtLg%3D (Pubitemid 40962100)
48. Korbelik M, Cecic I. Mechanism of tumor destruction by photodynamic therapy. In: Nalwa HS, editor. Handbook of photocochemistry and photobiology, vol. 4. Stevenson Ranch: American Scientific Publishers; 2003. p. 39-77.
49. S Karrer AK Bosserhoff P Weiderer M Landthaler RM Szeimies 2004 Keratinocyte-derived cytokines after photodynamic therapy and their paracrine induction of matrix metalloproteinases in fibroblasts Br J Dermatol 151 776 783 10.1111/j.1365-2133.2004.06209.x 15491416 1:CAS:528:DC%2BD2cXhtVKitr3E (Pubitemid 39482110)