Erythropoietin directly stimulates osteoclast precursors and induces bone loss

FASEB Journal

Volumn 29, Issue 5, 2015, Pages 1890-1900

  Hiram Bab, Sahar ^a   Liron, Tamar ^a   Deshet Unger, Naamit ^a   Mittelman, Moshe ^a   Gassmann, Max ^b   Rauner, Martina ^c   Franke, Kristin ^d   Wielockx, Ben ^d   Neumann, Drorit ^a   Gabet, Yankel ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^d DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Bone turnover; Macrophages; Osteoclastogenesis; Tg6 mice; Trabecular bone

Indexed keywords

JANUS KINASE 2; PHOSPHATIDYLINOSITOL 3 KINASE; RECOMBINANT ERYTHROPOIETIN; EPO PROTEIN, HUMAN; ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE TURNOVER; CELL DIFFERENTIATION; CELL STIMULATION; CONTROLLED STUDY; FEMALE; MACROPHAGE; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; OSSIFICATION; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; PRIORITY JOURNAL; TRABECULAR BONE; ANIMAL; APOPTOSIS; BONE DEVELOPMENT; C57BL MOUSE; CELL CULTURE; CELL PROLIFERATION; CYTOLOGY; ETIOLOGY; GENETICS; HUMAN; METABOLISM; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; WESTERN BLOTTING;

MUS;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BONE RESORPTION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; ERYTHROPOIETIN; FEMALE; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OSTEOCLASTS; OSTEOGENESIS; RANK LIGAND; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, ERYTHROPOIETIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; X-RAY MICROTOMOGRAPHY;

EID: 84932629963     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.14-259085     Document Type: Article

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