MacroH2A1 isoforms are associated with epigenetic markers for activation of lipogenic genes in fat-induced steatosis

FASEB Journal

Volumn 29, Issue 5, 2015, Pages 1676-1687

  Podrini, Christine ^a   Koffas, Apostolos ^a   Choksh, Shilpa ^a   Vinciguerra, Manlio ^b   Lelliott, Christopher J ^c   White, Jacqueline K ^c   Adissu, Hibret A ^d   Williams, Roger ^a   Greco, Azzura ^a  

^a INSTITUTE OF HEPATOLOGY   (United Kingdom)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Bivalent promoter; Histone methylation; Histone variants; Lipid uptake

Indexed keywords

HISTONE H2A; HISTONE H2A1; HISTONE H3; HISTONE H3 LYSINE 27ME3; HISTONE H3 LYSINE 4ME3; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; ATP5B PROTEIN, MOUSE; BIOLOGICAL MARKER; HISTONE; ISOPROTEIN; MACROH2A HISTONE; MESSENGER RNA; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;

ALTERNATIVE RNA SPLICING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; EPIGENETICS; FATTY LIVER; GENE CONTROL; GENE EXPRESSION; HUMAN; HUMAN CELL; LIPID DIET; LIPID METABOLISM; LIPID STORAGE; LIPID TRANSPORT; LIPOGENESIS; LIVER CELL; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROMOTER REGION; WESTERN BLOTTING; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; CELL CULTURE; DNA MICROARRAY; ENZYME IMMUNOASSAY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; GENETICS; KNOCKOUT MOUSE; LIPID PEROXIDATION; LIVER; LIVER CELL CARCINOMA; LIVER TUMOR; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

MUS;

ANIMALS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; DIET, HIGH-FAT; EPIGENOMICS; FATTY LIVER; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; HEPATOCYTES; HISTONES; HUMANS; IMMUNOENZYME TECHNIQUES; LIPID PEROXIDATION; LIVER; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROMOTER REGIONS, GENETIC; PROTEIN ISOFORMS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84932610910     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.14-262717     Document Type: Article

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