메뉴 건너뛰기




Volumn 8, Issue 382, 2015, Pages

DNA methylation regulates neuronal glutamatergic synaptic scaling

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; DACTINOMYCIN; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; GLUTAMATE RECEPTOR; N PHTHALOYLTRYPTOPHAN; RNA POLYMERASE; TETRODOTOXIN; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; PHTHALIMIDE DERIVATIVE; TRYPTOPHAN;

EID: 84932600238     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.aab0715     Document Type: Article
Times cited : (96)

References (75)
  • 1
    • 84884471932 scopus 로고    scopus 로고
    • TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation
    • G. A. Kaas, C. Zhong, D. E. Eason, D. L. Ross, R. V. Vachhani, G. L. Ming, J. R. King, H. Song, J. D. Sweatt, TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation. Neuron 79, 1086-1093 (2013).
    • (2013) Neuron , vol.79 , pp. 1086-1093
    • Kaas, G.A.1    Zhong, C.2    Eason, D.E.3    Ross, D.L.4    Vachhani, R.V.5    Ming, G.L.6    King, J.R.7    Song, H.8    Sweatt, J.D.9
  • 3
    • 36849154193 scopus 로고
    • Memory and molecular turnover
    • F. Crick, Memory and molecular turnover. Nature 312, 101 (1984).
    • (1984) Nature , vol.312 , pp. 101
    • Crick, F.1
  • 4
    • 0033533707 scopus 로고    scopus 로고
    • Is there an epigenetic component in long-term memory?
    • R. Holliday, Is there an epigenetic component in long-term memory? J. Theor. Biol. 200, 339-341 (1999).
    • (1999) J. Theor. Biol. , vol.200 , pp. 339-341
    • Holliday, R.1
  • 5
    • 77958580776 scopus 로고    scopus 로고
    • DNA methylation and memory formation
    • J. J. Day, J. D. Sweatt, DNA methylation and memory formation. Nat. Neurosci. 13, 1319-1323 (2010).
    • (2010) Nat. Neurosci. , vol.13 , pp. 1319-1323
    • Day, J.J.1    Sweatt, J.D.2
  • 7
    • 77950187447 scopus 로고    scopus 로고
    • Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
    • J. Feng, Y. Zhou, S. L. Campbell, T. Le, E. Li, J. D. Sweatt, A. J. Silva, G. Fan, Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat. Neurosci. 13, 423-430 (2010).
    • (2010) Nat. Neurosci. , vol.13 , pp. 423-430
    • Feng, J.1    Zhou, Y.2    Campbell, S.L.3    Le, T.4    Li, E.5    Sweatt, J.D.6    Silva, A.J.7    Fan, G.8
  • 8
    • 41649096261 scopus 로고    scopus 로고
    • DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity
    • C. A. Miller, S. L. Campbell, J. D. Sweatt, DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity. Neurobiol. Learn. Mem. 89, 599-603 (2008).
    • (2008) Neurobiol. Learn. Mem. , vol.89 , pp. 599-603
    • Miller, C.A.1    Campbell, S.L.2    Sweatt, J.D.3
  • 10
    • 33847614418 scopus 로고    scopus 로고
    • Covalent modification of DNA regulates memory formation
    • C. A. Miller, J. D. Sweatt, Covalent modification of DNA regulates memory formation. Neuron 53, 857-869 (2007).
    • (2007) Neuron , vol.53 , pp. 857-869
    • Miller, C.A.1    Sweatt, J.D.2
  • 11
    • 54849426071 scopus 로고    scopus 로고
    • Epigenetic regulation of bdnf gene transcription in the consolidation of fear memory
    • F. D. Lubin, T. L. Roth, J. D. Sweatt, Epigenetic regulation of bdnf gene transcription in the consolidation of fear memory. J. Neurosci. 28, 10576-10586 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 10576-10586
    • Lubin, F.D.1    Roth, T.L.2    Sweatt, J.D.3
  • 14
    • 79955538247 scopus 로고    scopus 로고
    • Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
    • J. U. Guo, Y. Su, C. Zhong, G. L. Ming, H. Song, Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell 145, 423-434 (2011).
    • (2011) Cell , vol.145 , pp. 423-434
    • Guo, J.U.1    Su, Y.2    Zhong, C.3    Ming, G.L.4    Song, H.5
  • 15
    • 80051712275 scopus 로고    scopus 로고
    • Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond
    • J. U. Guo, Y. Su, C. Zhong, G. L. Ming, H. Song, Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond. Cell Cycle 10, 2662-2668 (2011).
    • (2011) Cell Cycle , vol.10 , pp. 2662-2668
    • Guo, J.U.1    Su, Y.2    Zhong, C.3    Ming, G.L.4    Song, H.5
  • 16
    • 77956189495 scopus 로고    scopus 로고
    • Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
    • S. Ito, A. C. D'Alessio, O. V. Taranova, K. Hong, L. C. Sowers, Y. Zhang, Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 466, 1129-1133 (2010).
    • (2010) Nature , vol.466 , pp. 1129-1133
    • Ito, S.1    D'Alessio, A.C.2    Taranova, O.V.3    Hong, K.4    Sowers, L.C.5    Zhang, Y.6
  • 17
    • 66849119061 scopus 로고    scopus 로고
    • DNA excision repair proteins and Gadd45 as molecular players for active DNA demethylation
    • D. K. Ma, J. U. Guo, G. L. Ming, H. Song, DNA excision repair proteins and Gadd45 as molecular players for active DNA demethylation. Cell Cycle 8, 1526-1531 (2009).
    • (2009) Cell Cycle , vol.8 , pp. 1526-1531
    • Ma, D.K.1    Guo, J.U.2    Ming, G.L.3    Song, H.4
  • 20
    • 84870184296 scopus 로고    scopus 로고
    • Genetic deletion of gadd45b, a regulator of active DNA demethylation, enhances long-term memory and synaptic plasticity
    • F. A. Sultan, J. Wang, J. Tront, D. A. Liebermann, J. D. Sweatt, Genetic deletion of gadd45b, a regulator of active DNA demethylation, enhances long-term memory and synaptic plasticity. J. Neurosci. 32, 17059-17066 (2012).
    • (2012) J. Neurosci. , vol.32 , pp. 17059-17066
    • Sultan, F.A.1    Wang, J.2    Tront, J.3    Liebermann, D.A.4    Sweatt, J.D.5
  • 22
    • 84887009499 scopus 로고    scopus 로고
    • The emerging field of neuroepigenetics
    • J. D. Sweatt, The emerging field of neuroepigenetics. Neuron 80, 624-632 (2013).
    • (2013) Neuron , vol.80 , pp. 624-632
    • Sweatt, J.D.1
  • 24
    • 0033667165 scopus 로고    scopus 로고
    • Synaptic plasticity: Taming the beast
    • L. F. Abbott, S. B. Nelson, Synaptic plasticity: Taming the beast. Nat. Neurosci. 3, 1178-1183 (2000).
    • (2000) Nat. Neurosci. , vol.3 , pp. 1178-1183
    • Abbott, L.F.1    Nelson, S.B.2
  • 25
    • 40849138306 scopus 로고    scopus 로고
    • Rapid synaptic scaling induced by changes in postsynaptic firing
    • K. Ibata, Q. Sun, G. G. Turrigiano, Rapid synaptic scaling induced by changes in postsynaptic firing. Neuron 57, 819-826 (2008).
    • (2008) Neuron , vol.57 , pp. 819-826
    • Ibata, K.1    Sun, Q.2    Turrigiano, G.G.3
  • 26
    • 54549125798 scopus 로고    scopus 로고
    • The self-tuning neuron: Synaptic scaling of excitatory synapses
    • G. G. Turrigiano, The self-tuning neuron: Synaptic scaling of excitatory synapses. Cell 135, 422-435 (2008).
    • (2008) Cell , vol.135 , pp. 422-435
    • Turrigiano, G.G.1
  • 27
    • 0032567928 scopus 로고    scopus 로고
    • Activity-dependent scaling of quantal amplitude in neocortical neurons
    • G. G. Turrigiano, K. R. Leslie, N. S. Desai, L. C. Rutherford, S. B. Nelson, Activity-dependent scaling of quantal amplitude in neocortical neurons. Nature 391, 892-896 (1998).
    • (1998) Nature , vol.391 , pp. 892-896
    • Turrigiano, G.G.1    Leslie, K.R.2    Desai, N.S.3    Rutherford, L.C.4    Nelson, S.B.5
  • 28
    • 84894101365 scopus 로고    scopus 로고
    • Molecular mechanisms of homeostatic synaptic down-scaling
    • B. Siddoway, H. Hou, H. Xia, Molecular mechanisms of homeostatic synaptic down-scaling. Neuropharmacology 78, 38-44 (2014).
    • (2014) Neuropharmacology , vol.78 , pp. 38-44
    • Siddoway, B.1    Hou, H.2    Xia, H.3
  • 29
    • 84862305275 scopus 로고    scopus 로고
    • AMPA receptor trafficking in homeostatic synaptic plasticity: Functional molecules and signaling cascades
    • G. Wang, J. Gilbert, H. Y. Man, AMPA receptor trafficking in homeostatic synaptic plasticity: Functional molecules and signaling cascades. Neural Plast 2012, 825364 (2012).
    • (2012) Neural Plast , vol.2012 , pp. 825364
    • Wang, G.1    Gilbert, J.2    Man, H.Y.3
  • 30
    • 84861215494 scopus 로고    scopus 로고
    • An improved test for detecting multiplicative homeostatic synaptic scaling
    • J. Kim, R. W. Tsien, B. E. Alger, An improved test for detecting multiplicative homeostatic synaptic scaling. PLOS One 7, e37364 (2012).
    • (2012) PLOS One , vol.7 , pp. e37364
    • Kim, J.1    Tsien, R.W.2    Alger, B.E.3
  • 31
    • 77951665718 scopus 로고    scopus 로고
    • Reduction in endocannabinoid tone is a homeostatic mechanism for specific inhibitory synapses
    • J. Kim, B. E. Alger, Reduction in endocannabinoid tone is a homeostatic mechanism for specific inhibitory synapses. Nat Neurosci. 13, 592-600 (2010).
    • (2010) Nat Neurosci. , vol.13 , pp. 592-600
    • Kim, J.1    Alger, B.E.2
  • 32
    • 84881525169 scopus 로고    scopus 로고
    • Differential subcellular targeting of glutamate receptor subtypes during homeostatic synaptic plasticity
    • C. Soares, K. F. Lee, W. Nassrallah, J. C. Bíïque, Differential subcellular targeting of glutamate receptor subtypes during homeostatic synaptic plasticity. J. Neurosci. 33, 13547-13559 (2013).
    • (2013) J. Neurosci. , vol.33 , pp. 13547-13559
    • Soares, C.1    Lee, K.F.2    Nassrallah, W.3    Bíïque, J.C.4
  • 34
    • 23944511446 scopus 로고    scopus 로고
    • Adaptation to synaptic inactivity in hippo-campal neurons
    • T. C. Thiagarajan, M. Lindskog, R. W. Tsien, Adaptation to synaptic inactivity in hippo-campal neurons. Neuron 47, 725-737 (2005).
    • (2005) Neuron , vol.47 , pp. 725-737
    • Thiagarajan, T.C.1    Lindskog, M.2    Tsien, R.W.3
  • 35
    • 0032168158 scopus 로고    scopus 로고
    • BDNF has opposite effects on the quantal amplitude of pyramidal neuron and interneuron excitatory synapses
    • L. C. Rutherford, S. B. Nelson, G. G. Turrigiano, BDNF has opposite effects on the quantal amplitude of pyramidal neuron and interneuron excitatory synapses. Neuron 21, 521-530 (1998).
    • (1998) Neuron , vol.21 , pp. 521-530
    • Rutherford, L.C.1    Nelson, S.B.2    Turrigiano, G.G.3
  • 37
    • 33645086120 scopus 로고    scopus 로고
    • Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines
    • C. Stresemann, B. Brueckner, T. Musch, H. Stopper, F. Lyko, Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines. Cancer Res. 66, 2794-2800 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 2794-2800
    • Stresemann, C.1    Brueckner, B.2    Musch, T.3    Stopper, H.4    Lyko, F.5
  • 39
    • 38349044361 scopus 로고    scopus 로고
    • Activity-dependent suppression of miniature neurotransmission through the regulation of DNA methylation
    • E. D. Nelson, E. T. Kavalali, L. M. Monteggia, Activity-dependent suppression of miniature neurotransmission through the regulation of DNA methylation. J. Neurosci. 28, 395-406 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 395-406
    • Nelson, E.D.1    Kavalali, E.T.2    Monteggia, L.M.3
  • 40
    • 0020032366 scopus 로고
    • Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2'-deoxycytidine
    • F. Creusot, G. Acs, J. K. Christman, Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2'-deoxycytidine. J. Biol. Chem. 257, 2041-2048 (1982).
    • (1982) J. Biol. Chem. , vol.257 , pp. 2041-2048
    • Creusot, F.1    Acs, G.2    Christman, J.K.3
  • 41
    • 0000418476 scopus 로고
    • Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine
    • D. V. Santi, A. Norment, C. E. Garrett, Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine. Proc. Natl. Acad. Sci. U. S. A. 81, 6993-6997 (1984).
    • (1984) Proc. Natl. Acad. Sci. U. S. A. , vol.81 , pp. 6993-6997
    • Santi, D.V.1    Norment, A.2    Garrett, C.E.3
  • 42
    • 0036965821 scopus 로고    scopus 로고
    • Zebularine: A novel DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases
    • L. Zhou, X. Cheng, B. A. Connolly, M. J. Dickman, P. J. Hurd, D. P. Hornby, Zebularine: A novel DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases. J. Mol. Biol. 321, 591-599 (2002).
    • (2002) J. Mol. Biol. , vol.321 , pp. 591-599
    • Zhou, L.1    Cheng, X.2    Connolly, B.A.3    Dickman, M.J.4    Hurd, P.J.5    Hornby, D.P.6
  • 43
    • 0028151343 scopus 로고
    • Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation
    • R. Jüttermann, E. Li, R. Jaenisch, Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation. Proc. Natl. Acad. Sci. U. S. A. 91, 11797-11801 (1994).
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 11797-11801
    • Jüttermann, R.1    Li, E.2    Jaenisch, R.3
  • 44
    • 84866723225 scopus 로고    scopus 로고
    • A critical and cell-autonomous role for MeCP2 in synaptic scaling up
    • M. P. Blackman, B. Djukic, S. B. Nelson, G. G. Turrigiano, A critical and cell-autonomous role for MeCP2 in synaptic scaling up. J. Neurosci. 32, 13529-13536 (2012).
    • (2012) J. Neurosci. , vol.32 , pp. 13529-13536
    • Blackman, M.P.1    Djukic, B.2    Nelson, S.B.3    Turrigiano, G.G.4
  • 45
    • 84925957193 scopus 로고    scopus 로고
    • Targeting DNA methylation with small molecules: What's next?
    • A. Erdmann, L. Halby, J. Fahy, P. B. Arimondo, Targeting DNA methylation with small molecules: What's next? J. Med. Chem. 58, 2569-2583 (2015).
    • (2015) J. Med. Chem. , vol.58 , pp. 2569-2583
    • Erdmann, A.1    Halby, L.2    Fahy, J.3    Arimondo, P.B.4
  • 46
    • 33745211255 scopus 로고    scopus 로고
    • Antisense oligonucleotides: From design to therapeutic application
    • J. H. Chan, S. Lim, W. S. Wong, Antisense oligonucleotides: From design to therapeutic application. Clin. Exp. Pharmacol. Physiol. 33, 533-540 (2006).
    • (2006) Clin. Exp. Pharmacol. Physiol. , vol.33 , pp. 533-540
    • Chan, J.H.1    Lim, S.2    Wong, W.S.3
  • 47
    • 0033975328 scopus 로고    scopus 로고
    • Sensible use of antisense: How to use oligonucleotides as research tools
    • K. J. Myers, N. M. Dean, Sensible use of antisense: How to use oligonucleotides as research tools. Trends Pharmacol. Sci. 21, 19-23 (2000).
    • (2000) Trends Pharmacol. Sci. , vol.21 , pp. 19-23
    • Myers, K.J.1    Dean, N.M.2
  • 48
    • 0023447259 scopus 로고
    • Selective elimination of mRNAs in vivo: Complementary oligodeoxynucleotides promote RNA degradation by an RNase H-like activity
    • P. Dash, I. Lotan, M. Knapp, E. R. Kandel, P. Goelet, Selective elimination of mRNAs in vivo: Complementary oligodeoxynucleotides promote RNA degradation by an RNase H-like activity. Proc. Natl. Acad. Sci. U. S. A. 84, 7896-7900 (1987).
    • (1987) Proc. Natl. Acad. Sci. U. S. A. , vol.84 , pp. 7896-7900
    • Dash, P.1    Lotan, I.2    Knapp, M.3    Kandel, E.R.4    Goelet, P.5
  • 49
    • 0024041180 scopus 로고
    • Role of RNase H in hybrid-arrested translation by antisense oligonucleotides
    • R. Y. Walder, J. A. Walder, Role of RNase H in hybrid-arrested translation by antisense oligonucleotides. Proc. Natl. Acad. Sci. U. S. A. 85, 5011-5015 (1988).
    • (1988) Proc. Natl. Acad. Sci. U. S. A. , vol.85 , pp. 5011-5015
    • Walder, R.Y.1    Walder, J.A.2
  • 50
    • 0034015113 scopus 로고    scopus 로고
    • Phosphorothioate oligodeoxynucleotides: What is their origin and what is unique about them?
    • F. Eckstein, Phosphorothioate oligodeoxynucleotides: What is their origin and what is unique about them? Antisense Nucleic Acid Drug Dev. 10, 117-121 (2000).
    • (2000) Antisense Nucleic Acid Drug Dev. , vol.10 , pp. 117-121
    • Eckstein, F.1
  • 51
    • 0033555551 scopus 로고    scopus 로고
    • Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-α expression
    • R. A. McKay, L. J. Miraglia, L. L. Cummins, S. R. Owens, H. Sasmor, N. M. Dean, Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-α expression. J. Biol. Chem. 274, 1715-1722 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 1715-1722
    • McKay, R.A.1    Miraglia, L.J.2    Cummins, L.L.3    Owens, S.R.4    Sasmor, H.5    Dean, N.M.6
  • 52
    • 82955237522 scopus 로고    scopus 로고
    • Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene/allele-specific silencing of mutant huntingtin
    • J. B. Carroll, S. C. Warby, A. L. Southwell, C. N. Doty, S. Greenlee, N. Skotte, G. Hung, C. F. Bennett, S. M. Freier, M. R. Hayden, Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene/allele-specific silencing of mutant huntingtin. Mol. Ther. 19, 2178-2185 (2011).
    • (2011) Mol. Ther. , vol.19 , pp. 2178-2185
    • Carroll, J.B.1    Warby, S.C.2    Southwell, A.L.3    Doty, C.N.4    Greenlee, S.5    Skotte, N.6    Hung, G.7    Bennett, C.F.8    Freier, S.M.9    Hayden, M.R.10
  • 54
    • 0034928712 scopus 로고    scopus 로고
    • Synaptic modification by correlated activity: Hebb's postulate revisited
    • G. Bi, M. Poo, Synaptic modification by correlated activity: Hebb's postulate revisited. Annu. Rev. Neurosci. 24, 139-166 (2001).
    • (2001) Annu. Rev. Neurosci. , vol.24 , pp. 139-166
    • Bi, G.1    Poo, M.2
  • 56
    • 5344241223 scopus 로고    scopus 로고
    • LTP and LTD: An embarrassment of riches
    • R. C. Malenka, M. F. Bear, LTP and LTD: An embarrassment of riches. Neuron 44, 5-21 (2004).
    • (2004) Neuron , vol.44 , pp. 5-21
    • Malenka, R.C.1    Bear, M.F.2
  • 57
    • 84861189663 scopus 로고    scopus 로고
    • Epigenetic regulation of reelin and brain-derived neurotrophic factor genes in long-term potentiation in rat medial prefrontal cortex
    • L. Sui, Y. Wang, L. H. Ju, M. Chen, Epigenetic regulation of reelin and brain-derived neurotrophic factor genes in long-term potentiation in rat medial prefrontal cortex. Neurobiol. Learn. Mem. 97, 425-440 (2012).
    • (2012) Neurobiol. Learn. Mem. , vol.97 , pp. 425-440
    • Sui, L.1    Wang, Y.2    Ju, L.H.3    Chen, M.4
  • 58
    • 55049136860 scopus 로고    scopus 로고
    • Strength through diversity
    • S. B. Nelson, G. G. Turrigiano, Strength through diversity. Neuron 60, 477-482 (2008).
    • (2008) Neuron , vol.60 , pp. 477-482
    • Nelson, S.B.1    Turrigiano, G.G.2
  • 60
    • 33645882216 scopus 로고    scopus 로고
    • MeCP2-dependent transcriptional repression regulates excitatory neurotransmission
    • E. D. Nelson, E. T. Kavalali, L. M. Monteggia, MeCP2-dependent transcriptional repression regulates excitatory neurotransmission. Curr. Biol. 16, 710-716 (2006).
    • (2006) Curr. Biol. , vol.16 , pp. 710-716
    • Nelson, E.D.1    Kavalali, E.T.2    Monteggia, L.M.3
  • 62
    • 45249121770 scopus 로고    scopus 로고
    • Synapse-specific adaptations to inactivity in hippocampal circuits achieve homeostatic gain control while dampening network reverberation
    • J. Kim, R. W. Tsien, Synapse-specific adaptations to inactivity in hippocampal circuits achieve homeostatic gain control while dampening network reverberation. Neuron 58, 925-937 (2008).
    • (2008) Neuron , vol.58 , pp. 925-937
    • Kim, J.1    Tsien, R.W.2
  • 63
    • 84872175082 scopus 로고    scopus 로고
    • Mossy fiber-CA3 synapses mediate homeostatic plasticity in mature hippocampal neurons
    • K. J. Lee, B. N. Queenan, A. M. Rozeboom, R. Bellmore, S. T. Lim, S. Vicini, D. T. Pak, Mossy fiber-CA3 synapses mediate homeostatic plasticity in mature hippocampal neurons. Neuron 77, 99-114 (2013).
    • (2013) Neuron , vol.77 , pp. 99-114
    • Lee, K.J.1    Queenan, B.N.2    Rozeboom, A.M.3    Bellmore, R.4    Lim, S.T.5    Vicini, S.6    Pak, D.T.7
  • 64
    • 83355171133 scopus 로고    scopus 로고
    • Homeostatic regulation of AMPA receptor trafficking and degradation by light-controlled single-synaptic activation
    • Q. Hou, J. Gilbert, H. Y. Man, Homeostatic regulation of AMPA receptor trafficking and degradation by light-controlled single-synaptic activation. Neuron 72, 806-818 (2011).
    • (2011) Neuron , vol.72 , pp. 806-818
    • Hou, Q.1    Gilbert, J.2    Man, H.Y.3
  • 65
    • 77953951999 scopus 로고    scopus 로고
    • Metaplasticity at single glutamatergic synapses
    • M. C. Lee, R. Yasuda, M. D. Ehlers, Metaplasticity at single glutamatergic synapses. Neuron 66, 859-870 (2010).
    • (2010) Neuron , vol.66 , pp. 859-870
    • Lee, M.C.1    Yasuda, R.2    Ehlers, M.D.3
  • 67
    • 0035873225 scopus 로고    scopus 로고
    • Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription
    • F. Fuks, W. A. Burgers, N. Godin, M. Kasai, T. Kouzarides, Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription. EMBO J. 20, 2536-2544 (2001).
    • (2001) EMBO J. , vol.20 , pp. 2536-2544
    • Fuks, F.1    Burgers, W.A.2    Godin, N.3    Kasai, M.4    Kouzarides, T.5
  • 69
    • 0036683055 scopus 로고    scopus 로고
    • Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyl-transferases
    • G. D. Kim, J. Ni, N. Kelesoglu, R. J. Roberts, S. Pradhan, Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyl-transferases. EMBO J. 21, 4183-4195 (2002).
    • (2002) EMBO J. , vol.21 , pp. 4183-4195
    • Kim, G.D.1    Ni, J.2    Kelesoglu, N.3    Roberts, R.J.4    Pradhan, S.5
  • 70
    • 84873038036 scopus 로고    scopus 로고
    • Chronic inactivation of a neural circuit enhances LTP by inducing silent synapse formation
    • K. L. Arendt, F. Sarti, L. Chen, Chronic inactivation of a neural circuit enhances LTP by inducing silent synapse formation. J. Neurosci. 33, 2087-2096 (2013).
    • (2013) J. Neurosci. , vol.33 , pp. 2087-2096
    • Arendt, K.L.1    Sarti, F.2    Chen, L.3
  • 72
    • 33845865244 scopus 로고    scopus 로고
    • LTP and adaptation to inactivity: Overlapping mechanisms and implications for metaplasticity
    • T. C. Thiagarajan, M. Lindskog, A. Malgaroli, R. W. Tsien, LTP and adaptation to inactivity: Overlapping mechanisms and implications for metaplasticity. Neuropharmacology 52, 156-175 (2007).
    • (2007) Neuropharmacology , vol.52 , pp. 156-175
    • Thiagarajan, T.C.1    Lindskog, M.2    Malgaroli, A.3    Tsien, R.W.4
  • 75
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • M. W. Pfaffl, A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29, e45 (2001).
    • (2001) Nucleic Acids Res. , vol.29 , pp. e45
    • Pfaffl, M.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.