-
1
-
-
84884471932
-
TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation
-
G. A. Kaas, C. Zhong, D. E. Eason, D. L. Ross, R. V. Vachhani, G. L. Ming, J. R. King, H. Song, J. D. Sweatt, TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation. Neuron 79, 1086-1093 (2013).
-
(2013)
Neuron
, vol.79
, pp. 1086-1093
-
-
Kaas, G.A.1
Zhong, C.2
Eason, D.E.3
Ross, D.L.4
Vachhani, R.V.5
Ming, G.L.6
King, J.R.7
Song, H.8
Sweatt, J.D.9
-
2
-
-
84926457777
-
DNA methylation regulates neurophysiological spatial representation in memory formation
-
E. D. Roth, T. L. Roth, K. M. Money, S. Sen Gupta, D. E. Eason, J. D. Sweatt, DNA methylation regulates neurophysiological spatial representation in memory formation. Neuroepigenetics 2, 1-8 (2015).
-
(2015)
Neuroepigenetics
, vol.2
, pp. 1-8
-
-
Roth, E.D.1
Roth, T.L.2
Money, K.M.3
Sen Gupta, S.4
Eason, D.E.5
Sweatt, J.D.6
-
3
-
-
36849154193
-
Memory and molecular turnover
-
F. Crick, Memory and molecular turnover. Nature 312, 101 (1984).
-
(1984)
Nature
, vol.312
, pp. 101
-
-
Crick, F.1
-
4
-
-
0033533707
-
Is there an epigenetic component in long-term memory?
-
R. Holliday, Is there an epigenetic component in long-term memory? J. Theor. Biol. 200, 339-341 (1999).
-
(1999)
J. Theor. Biol.
, vol.200
, pp. 339-341
-
-
Holliday, R.1
-
5
-
-
77958580776
-
DNA methylation and memory formation
-
J. J. Day, J. D. Sweatt, DNA methylation and memory formation. Nat. Neurosci. 13, 1319-1323 (2010).
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 1319-1323
-
-
Day, J.J.1
Sweatt, J.D.2
-
6
-
-
33744920106
-
Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus
-
J. M. Levenson, T. L. Roth, F. D. Lubin, C. A. Miller, I. C. Huang, P. Desai, L. M. Malone, J. D. Sweatt, Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus. J. Biol. Chem. 281, 15763-15773 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 15763-15773
-
-
Levenson, J.M.1
Roth, T.L.2
Lubin, F.D.3
Miller, C.A.4
Huang, I.C.5
Desai, P.6
Malone, L.M.7
Sweatt, J.D.8
-
7
-
-
77950187447
-
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
-
J. Feng, Y. Zhou, S. L. Campbell, T. Le, E. Li, J. D. Sweatt, A. J. Silva, G. Fan, Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat. Neurosci. 13, 423-430 (2010).
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 423-430
-
-
Feng, J.1
Zhou, Y.2
Campbell, S.L.3
Le, T.4
Li, E.5
Sweatt, J.D.6
Silva, A.J.7
Fan, G.8
-
8
-
-
41649096261
-
DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity
-
C. A. Miller, S. L. Campbell, J. D. Sweatt, DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity. Neurobiol. Learn. Mem. 89, 599-603 (2008).
-
(2008)
Neurobiol. Learn. Mem.
, vol.89
, pp. 599-603
-
-
Miller, C.A.1
Campbell, S.L.2
Sweatt, J.D.3
-
9
-
-
77952886110
-
Cortical DNA methylation maintains remote memory
-
C. A. Miller, C. F. Gavin, J. A. White, R. R. Parrish, A. Honasoge, C. R. Yancey, I. M. Rivera, M. D. Rubio, G. Rumbaugh, J. D. Sweatt, Cortical DNA methylation maintains remote memory. Nat. Neurosci. 13, 664-666 (2010).
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 664-666
-
-
Miller, C.A.1
Gavin, C.F.2
White, J.A.3
Parrish, R.R.4
Honasoge, A.5
Yancey, C.R.6
Rivera, I.M.7
Rubio, M.D.8
Rumbaugh, G.9
Sweatt, J.D.10
-
10
-
-
33847614418
-
Covalent modification of DNA regulates memory formation
-
C. A. Miller, J. D. Sweatt, Covalent modification of DNA regulates memory formation. Neuron 53, 857-869 (2007).
-
(2007)
Neuron
, vol.53
, pp. 857-869
-
-
Miller, C.A.1
Sweatt, J.D.2
-
11
-
-
54849426071
-
Epigenetic regulation of bdnf gene transcription in the consolidation of fear memory
-
F. D. Lubin, T. L. Roth, J. D. Sweatt, Epigenetic regulation of bdnf gene transcription in the consolidation of fear memory. J. Neurosci. 28, 10576-10586 (2008).
-
(2008)
J. Neurosci.
, vol.28
, pp. 10576-10586
-
-
Lubin, F.D.1
Roth, T.L.2
Sweatt, J.D.3
-
12
-
-
84884901586
-
DNA methylation regulates associative reward learning
-
J. J. Day, D. Childs, M. C. Guzman-Karlsson, M. Kibe, J. Moulden, E. Song, A. Tahir, J. D. Sweatt, DNA methylation regulates associative reward learning. Nat. Neurosci. 16, 1445-1452 (2013).
-
(2013)
Nat. Neurosci.
, vol.16
, pp. 1445-1452
-
-
Day, J.J.1
Childs, D.2
Guzman-Karlsson, M.C.3
Kibe, M.4
Moulden, J.5
Song, E.6
Tahir, A.7
Sweatt, J.D.8
-
13
-
-
80053270332
-
Neuronal activity modifies the DNA methylation landscape in the adult brain
-
J. U. Guo, D. K. Ma, H. Mo, M. P. Ball, M. H. Jang, M. A. Bonaguidi, J. A. Balazer, H. L. Eaves, B. Xie, E. Ford, K. Zhang, G. L. Ming, Y. Gao, H. Song, Neuronal activity modifies the DNA methylation landscape in the adult brain. Nat. Neurosci. 14, 1345-1351 (2011).
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 1345-1351
-
-
Guo, J.U.1
Ma, D.K.2
Mo, H.3
Ball, M.P.4
Jang, M.H.5
Bonaguidi, M.A.6
Balazer, J.A.7
Eaves, H.L.8
Xie, B.9
Ford, E.10
Zhang, K.11
Ming, G.L.12
Gao, Y.13
Song, H.14
-
14
-
-
79955538247
-
Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
-
J. U. Guo, Y. Su, C. Zhong, G. L. Ming, H. Song, Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell 145, 423-434 (2011).
-
(2011)
Cell
, vol.145
, pp. 423-434
-
-
Guo, J.U.1
Su, Y.2
Zhong, C.3
Ming, G.L.4
Song, H.5
-
15
-
-
80051712275
-
Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond
-
J. U. Guo, Y. Su, C. Zhong, G. L. Ming, H. Song, Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond. Cell Cycle 10, 2662-2668 (2011).
-
(2011)
Cell Cycle
, vol.10
, pp. 2662-2668
-
-
Guo, J.U.1
Su, Y.2
Zhong, C.3
Ming, G.L.4
Song, H.5
-
16
-
-
77956189495
-
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
-
S. Ito, A. C. D'Alessio, O. V. Taranova, K. Hong, L. C. Sowers, Y. Zhang, Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 466, 1129-1133 (2010).
-
(2010)
Nature
, vol.466
, pp. 1129-1133
-
-
Ito, S.1
D'Alessio, A.C.2
Taranova, O.V.3
Hong, K.4
Sowers, L.C.5
Zhang, Y.6
-
17
-
-
66849119061
-
DNA excision repair proteins and Gadd45 as molecular players for active DNA demethylation
-
D. K. Ma, J. U. Guo, G. L. Ming, H. Song, DNA excision repair proteins and Gadd45 as molecular players for active DNA demethylation. Cell Cycle 8, 1526-1531 (2009).
-
(2009)
Cell Cycle
, vol.8
, pp. 1526-1531
-
-
Ma, D.K.1
Guo, J.U.2
Ming, G.L.3
Song, H.4
-
18
-
-
60749094831
-
Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis
-
D. K. Ma, M. H. Jang, J. U. Guo, Y. Kitabatake, M. L. Chang, N. Pow-Anpongkul, R. A. Flavell, B. Lu, G. L. Ming, H. Song, Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis. Science 323, 1074-1077 (2009).
-
(2009)
Science
, vol.323
, pp. 1074-1077
-
-
Ma, D.K.1
Jang, M.H.2
Guo, J.U.3
Kitabatake, Y.4
Chang, M.L.5
Pow-Anpongkul, N.6
Flavell, R.A.7
Lu, B.8
Ming, G.L.9
Song, H.10
-
19
-
-
84884241288
-
Tet1 is critical for neuronal activity-regulated gene expression and memory extinction
-
A. Rudenko, M. M. Dawlaty, J. Seo, A. W. Cheng, J. Meng, T. Le, K. F. Faull, R. Jaenisch, L. H. Tsai, Tet1 is critical for neuronal activity-regulated gene expression and memory extinction. Neuron 79, 1109-1122 (2013).
-
(2013)
Neuron
, vol.79
, pp. 1109-1122
-
-
Rudenko, A.1
Dawlaty, M.M.2
Seo, J.3
Cheng, A.W.4
Meng, J.5
Le, T.6
Faull, K.F.7
Jaenisch, R.8
Tsai, L.H.9
-
20
-
-
84870184296
-
Genetic deletion of gadd45b, a regulator of active DNA demethylation, enhances long-term memory and synaptic plasticity
-
F. A. Sultan, J. Wang, J. Tront, D. A. Liebermann, J. D. Sweatt, Genetic deletion of gadd45b, a regulator of active DNA demethylation, enhances long-term memory and synaptic plasticity. J. Neurosci. 32, 17059-17066 (2012).
-
(2012)
J. Neurosci.
, vol.32
, pp. 17059-17066
-
-
Sultan, F.A.1
Wang, J.2
Tront, J.3
Liebermann, D.A.4
Sweatt, J.D.5
-
21
-
-
84881178902
-
Tet1 regulates adult hippocampal neurogenesis and cognition
-
R. R. Zhang, Q. Y. Cui, K. Murai, Y. C. Lim, Z. D. Smith, S. Jin, P. Ye, L. Rosa, Y. K. Lee, H. P. Wu, W. Liu, Z. M. Xu, L. Yang, Y. Q. Ding, F. Tang, A. Meissner, C. Ding, Y. Shi, G. L. Xu, Tet1 regulates adult hippocampal neurogenesis and cognition. Cell Stem Cell 13, 237-245 (2013).
-
(2013)
Cell Stem Cell
, vol.13
, pp. 237-245
-
-
Zhang, R.R.1
Cui, Q.Y.2
Murai, K.3
Lim, Y.C.4
Smith, Z.D.5
Jin, S.6
Ye, P.7
Rosa, L.8
Lee, Y.K.9
Wu, H.P.10
Liu, W.11
Xu, Z.M.12
Yang, L.13
Ding, Y.Q.14
Tang, F.15
Meissner, A.16
Ding, C.17
Shi, Y.18
Xu, G.L.19
-
22
-
-
84887009499
-
The emerging field of neuroepigenetics
-
J. D. Sweatt, The emerging field of neuroepigenetics. Neuron 80, 624-632 (2013).
-
(2013)
Neuron
, vol.80
, pp. 624-632
-
-
Sweatt, J.D.1
-
23
-
-
84898898550
-
Transcrip-tional and epigenetic regulation of Hebbian and non-Hebbian plasticity
-
M. C. Guzman-Karlsson, J. P. Meadows, C. F. Gavin, J. J. Hablitz, J. D. Sweatt, Transcrip-tional and epigenetic regulation of Hebbian and non-Hebbian plasticity. Neuropharma-cology 80, 3-17 (2014).
-
(2014)
Neuropharma-cology
, vol.80
, pp. 3-17
-
-
Guzman-Karlsson, M.C.1
Meadows, J.P.2
Gavin, C.F.3
Hablitz, J.J.4
Sweatt, J.D.5
-
24
-
-
0033667165
-
Synaptic plasticity: Taming the beast
-
L. F. Abbott, S. B. Nelson, Synaptic plasticity: Taming the beast. Nat. Neurosci. 3, 1178-1183 (2000).
-
(2000)
Nat. Neurosci.
, vol.3
, pp. 1178-1183
-
-
Abbott, L.F.1
Nelson, S.B.2
-
25
-
-
40849138306
-
Rapid synaptic scaling induced by changes in postsynaptic firing
-
K. Ibata, Q. Sun, G. G. Turrigiano, Rapid synaptic scaling induced by changes in postsynaptic firing. Neuron 57, 819-826 (2008).
-
(2008)
Neuron
, vol.57
, pp. 819-826
-
-
Ibata, K.1
Sun, Q.2
Turrigiano, G.G.3
-
26
-
-
54549125798
-
The self-tuning neuron: Synaptic scaling of excitatory synapses
-
G. G. Turrigiano, The self-tuning neuron: Synaptic scaling of excitatory synapses. Cell 135, 422-435 (2008).
-
(2008)
Cell
, vol.135
, pp. 422-435
-
-
Turrigiano, G.G.1
-
27
-
-
0032567928
-
Activity-dependent scaling of quantal amplitude in neocortical neurons
-
G. G. Turrigiano, K. R. Leslie, N. S. Desai, L. C. Rutherford, S. B. Nelson, Activity-dependent scaling of quantal amplitude in neocortical neurons. Nature 391, 892-896 (1998).
-
(1998)
Nature
, vol.391
, pp. 892-896
-
-
Turrigiano, G.G.1
Leslie, K.R.2
Desai, N.S.3
Rutherford, L.C.4
Nelson, S.B.5
-
28
-
-
84894101365
-
Molecular mechanisms of homeostatic synaptic down-scaling
-
B. Siddoway, H. Hou, H. Xia, Molecular mechanisms of homeostatic synaptic down-scaling. Neuropharmacology 78, 38-44 (2014).
-
(2014)
Neuropharmacology
, vol.78
, pp. 38-44
-
-
Siddoway, B.1
Hou, H.2
Xia, H.3
-
29
-
-
84862305275
-
AMPA receptor trafficking in homeostatic synaptic plasticity: Functional molecules and signaling cascades
-
G. Wang, J. Gilbert, H. Y. Man, AMPA receptor trafficking in homeostatic synaptic plasticity: Functional molecules and signaling cascades. Neural Plast 2012, 825364 (2012).
-
(2012)
Neural Plast
, vol.2012
, pp. 825364
-
-
Wang, G.1
Gilbert, J.2
Man, H.Y.3
-
30
-
-
84861215494
-
An improved test for detecting multiplicative homeostatic synaptic scaling
-
J. Kim, R. W. Tsien, B. E. Alger, An improved test for detecting multiplicative homeostatic synaptic scaling. PLOS One 7, e37364 (2012).
-
(2012)
PLOS One
, vol.7
, pp. e37364
-
-
Kim, J.1
Tsien, R.W.2
Alger, B.E.3
-
31
-
-
77951665718
-
Reduction in endocannabinoid tone is a homeostatic mechanism for specific inhibitory synapses
-
J. Kim, B. E. Alger, Reduction in endocannabinoid tone is a homeostatic mechanism for specific inhibitory synapses. Nat Neurosci. 13, 592-600 (2010).
-
(2010)
Nat Neurosci.
, vol.13
, pp. 592-600
-
-
Kim, J.1
Alger, B.E.2
-
32
-
-
84881525169
-
Differential subcellular targeting of glutamate receptor subtypes during homeostatic synaptic plasticity
-
C. Soares, K. F. Lee, W. Nassrallah, J. C. Bíïque, Differential subcellular targeting of glutamate receptor subtypes during homeostatic synaptic plasticity. J. Neurosci. 33, 13547-13559 (2013).
-
(2013)
J. Neurosci.
, vol.33
, pp. 13547-13559
-
-
Soares, C.1
Lee, K.F.2
Nassrallah, W.3
Bíïque, J.C.4
-
33
-
-
33750503402
-
Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors
-
J. D. Shepherd, G. Rumbaugh, J. Wu, S. Chowdhury, N. Plath, D. Kuhl, R. L. Huganir, P. F. Worley, Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors. Neuron 52, 475-484 (2006).
-
(2006)
Neuron
, vol.52
, pp. 475-484
-
-
Shepherd, J.D.1
Rumbaugh, G.2
Wu, J.3
Chowdhury, S.4
Plath, N.5
Kuhl, D.6
Huganir, R.L.7
Worley, P.F.8
-
34
-
-
23944511446
-
Adaptation to synaptic inactivity in hippo-campal neurons
-
T. C. Thiagarajan, M. Lindskog, R. W. Tsien, Adaptation to synaptic inactivity in hippo-campal neurons. Neuron 47, 725-737 (2005).
-
(2005)
Neuron
, vol.47
, pp. 725-737
-
-
Thiagarajan, T.C.1
Lindskog, M.2
Tsien, R.W.3
-
35
-
-
0032168158
-
BDNF has opposite effects on the quantal amplitude of pyramidal neuron and interneuron excitatory synapses
-
L. C. Rutherford, S. B. Nelson, G. G. Turrigiano, BDNF has opposite effects on the quantal amplitude of pyramidal neuron and interneuron excitatory synapses. Neuron 21, 521-530 (1998).
-
(1998)
Neuron
, vol.21
, pp. 521-530
-
-
Rutherford, L.C.1
Nelson, S.B.2
Turrigiano, G.G.3
-
36
-
-
22244435605
-
Epigenetic reactivation of tumor suppressor genes by a novel small-molecule inhibitor of human DNA methyltransferases
-
B. Brueckner, R. Garcia Boy, P. Siedlecki, T. Musch, H. C. Kliem, P. Zielenkiewicz, S. Suhai, M. Wiessler, F. Lyko, Epigenetic reactivation of tumor suppressor genes by a novel small-molecule inhibitor of human DNA methyltransferases. Cancer Res. 65, 6305-6311 (2005).
-
(2005)
Cancer Res.
, vol.65
, pp. 6305-6311
-
-
Brueckner, B.1
Garcia Boy, R.2
Siedlecki, P.3
Musch, T.4
Kliem, H.C.5
Zielenkiewicz, P.6
Suhai, S.7
Wiessler, M.8
Lyko, F.9
-
37
-
-
33645086120
-
Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines
-
C. Stresemann, B. Brueckner, T. Musch, H. Stopper, F. Lyko, Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines. Cancer Res. 66, 2794-2800 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 2794-2800
-
-
Stresemann, C.1
Brueckner, B.2
Musch, T.3
Stopper, H.4
Lyko, F.5
-
38
-
-
77956139754
-
Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens
-
Q. La Plant, V. Vialou, H. E. Covington III, D. Dumitriu, J. Feng, B. L. Warren, I. Maze, D. M. Dietz, E. L. Watts, S. D. Iñiguez, J. W. Koo, E. Mouzon, W. Renthal, F. Hollis, H. Wang, M. A. Noonan, Y. Ren, A. J. Eisch, C. A. Bolaños, M. Kabbaj, G. Xiao, R. L. Neve, Y. L. Hurd, R. S. Oosting, G. Fan, J. H. Morrison, E. J. Nestler, Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nat. Neurosci. 13, 1137-1143 (2010).
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 1137-1143
-
-
La Plant, Q.1
Vialou, V.2
Covington, H.E.3
Dumitriu, D.4
Feng, J.5
Warren, B.L.6
Maze, I.7
Dietz, D.M.8
Watts, E.L.9
Iñiguez, S.D.10
Koo, J.W.11
Mouzon, E.12
Renthal, W.13
Hollis, F.14
Wang, H.15
Noonan, M.A.16
Ren, Y.17
Eisch, A.J.18
Bolaños, C.A.19
Kabbaj, M.20
Xiao, G.21
Neve, R.L.22
Hurd, Y.L.23
Oosting, R.S.24
Fan, G.25
Morrison, J.H.26
Nestler, E.J.27
more..
-
39
-
-
38349044361
-
Activity-dependent suppression of miniature neurotransmission through the regulation of DNA methylation
-
E. D. Nelson, E. T. Kavalali, L. M. Monteggia, Activity-dependent suppression of miniature neurotransmission through the regulation of DNA methylation. J. Neurosci. 28, 395-406 (2008).
-
(2008)
J. Neurosci.
, vol.28
, pp. 395-406
-
-
Nelson, E.D.1
Kavalali, E.T.2
Monteggia, L.M.3
-
40
-
-
0020032366
-
Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2'-deoxycytidine
-
F. Creusot, G. Acs, J. K. Christman, Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2'-deoxycytidine. J. Biol. Chem. 257, 2041-2048 (1982).
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 2041-2048
-
-
Creusot, F.1
Acs, G.2
Christman, J.K.3
-
41
-
-
0000418476
-
Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine
-
D. V. Santi, A. Norment, C. E. Garrett, Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine. Proc. Natl. Acad. Sci. U. S. A. 81, 6993-6997 (1984).
-
(1984)
Proc. Natl. Acad. Sci. U. S. A.
, vol.81
, pp. 6993-6997
-
-
Santi, D.V.1
Norment, A.2
Garrett, C.E.3
-
42
-
-
0036965821
-
Zebularine: A novel DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases
-
L. Zhou, X. Cheng, B. A. Connolly, M. J. Dickman, P. J. Hurd, D. P. Hornby, Zebularine: A novel DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases. J. Mol. Biol. 321, 591-599 (2002).
-
(2002)
J. Mol. Biol.
, vol.321
, pp. 591-599
-
-
Zhou, L.1
Cheng, X.2
Connolly, B.A.3
Dickman, M.J.4
Hurd, P.J.5
Hornby, D.P.6
-
43
-
-
0028151343
-
Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation
-
R. Jüttermann, E. Li, R. Jaenisch, Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation. Proc. Natl. Acad. Sci. U. S. A. 91, 11797-11801 (1994).
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 11797-11801
-
-
Jüttermann, R.1
Li, E.2
Jaenisch, R.3
-
44
-
-
84866723225
-
A critical and cell-autonomous role for MeCP2 in synaptic scaling up
-
M. P. Blackman, B. Djukic, S. B. Nelson, G. G. Turrigiano, A critical and cell-autonomous role for MeCP2 in synaptic scaling up. J. Neurosci. 32, 13529-13536 (2012).
-
(2012)
J. Neurosci.
, vol.32
, pp. 13529-13536
-
-
Blackman, M.P.1
Djukic, B.2
Nelson, S.B.3
Turrigiano, G.G.4
-
45
-
-
84925957193
-
Targeting DNA methylation with small molecules: What's next?
-
A. Erdmann, L. Halby, J. Fahy, P. B. Arimondo, Targeting DNA methylation with small molecules: What's next? J. Med. Chem. 58, 2569-2583 (2015).
-
(2015)
J. Med. Chem.
, vol.58
, pp. 2569-2583
-
-
Erdmann, A.1
Halby, L.2
Fahy, J.3
Arimondo, P.B.4
-
46
-
-
33745211255
-
Antisense oligonucleotides: From design to therapeutic application
-
J. H. Chan, S. Lim, W. S. Wong, Antisense oligonucleotides: From design to therapeutic application. Clin. Exp. Pharmacol. Physiol. 33, 533-540 (2006).
-
(2006)
Clin. Exp. Pharmacol. Physiol.
, vol.33
, pp. 533-540
-
-
Chan, J.H.1
Lim, S.2
Wong, W.S.3
-
47
-
-
0033975328
-
Sensible use of antisense: How to use oligonucleotides as research tools
-
K. J. Myers, N. M. Dean, Sensible use of antisense: How to use oligonucleotides as research tools. Trends Pharmacol. Sci. 21, 19-23 (2000).
-
(2000)
Trends Pharmacol. Sci.
, vol.21
, pp. 19-23
-
-
Myers, K.J.1
Dean, N.M.2
-
48
-
-
0023447259
-
Selective elimination of mRNAs in vivo: Complementary oligodeoxynucleotides promote RNA degradation by an RNase H-like activity
-
P. Dash, I. Lotan, M. Knapp, E. R. Kandel, P. Goelet, Selective elimination of mRNAs in vivo: Complementary oligodeoxynucleotides promote RNA degradation by an RNase H-like activity. Proc. Natl. Acad. Sci. U. S. A. 84, 7896-7900 (1987).
-
(1987)
Proc. Natl. Acad. Sci. U. S. A.
, vol.84
, pp. 7896-7900
-
-
Dash, P.1
Lotan, I.2
Knapp, M.3
Kandel, E.R.4
Goelet, P.5
-
49
-
-
0024041180
-
Role of RNase H in hybrid-arrested translation by antisense oligonucleotides
-
R. Y. Walder, J. A. Walder, Role of RNase H in hybrid-arrested translation by antisense oligonucleotides. Proc. Natl. Acad. Sci. U. S. A. 85, 5011-5015 (1988).
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 5011-5015
-
-
Walder, R.Y.1
Walder, J.A.2
-
50
-
-
0034015113
-
Phosphorothioate oligodeoxynucleotides: What is their origin and what is unique about them?
-
F. Eckstein, Phosphorothioate oligodeoxynucleotides: What is their origin and what is unique about them? Antisense Nucleic Acid Drug Dev. 10, 117-121 (2000).
-
(2000)
Antisense Nucleic Acid Drug Dev.
, vol.10
, pp. 117-121
-
-
Eckstein, F.1
-
51
-
-
0033555551
-
Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-α expression
-
R. A. McKay, L. J. Miraglia, L. L. Cummins, S. R. Owens, H. Sasmor, N. M. Dean, Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-α expression. J. Biol. Chem. 274, 1715-1722 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1715-1722
-
-
McKay, R.A.1
Miraglia, L.J.2
Cummins, L.L.3
Owens, S.R.4
Sasmor, H.5
Dean, N.M.6
-
52
-
-
82955237522
-
Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene/allele-specific silencing of mutant huntingtin
-
J. B. Carroll, S. C. Warby, A. L. Southwell, C. N. Doty, S. Greenlee, N. Skotte, G. Hung, C. F. Bennett, S. M. Freier, M. R. Hayden, Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene/allele-specific silencing of mutant huntingtin. Mol. Ther. 19, 2178-2185 (2011).
-
(2011)
Mol. Ther.
, vol.19
, pp. 2178-2185
-
-
Carroll, J.B.1
Warby, S.C.2
Southwell, A.L.3
Doty, C.N.4
Greenlee, S.5
Skotte, N.6
Hung, G.7
Bennett, C.F.8
Freier, S.M.9
Hayden, M.R.10
-
53
-
-
84929959512
-
Tet3 regulates synaptic transmission and homeostatic plasticity via DNA oxidation and repair
-
H. Yu, Y. Su, J. Shin, C. Zhong, J. U. Guo, Y. L. Weng, F. Gao, D. H. Geschwind, G. Coppola, G. L. Ming, H. Song, Tet3 regulates synaptic transmission and homeostatic plasticity via DNA oxidation and repair. Nat. Neurosci. 18, 836-843 (2015).
-
(2015)
Nat. Neurosci.
, vol.18
, pp. 836-843
-
-
Yu, H.1
Su, Y.2
Shin, J.3
Zhong, C.4
Guo, J.U.5
Weng, Y.L.6
Gao, F.7
Geschwind, D.H.8
Coppola, G.9
Ming, G.L.10
Song, H.11
-
54
-
-
0034928712
-
Synaptic modification by correlated activity: Hebb's postulate revisited
-
G. Bi, M. Poo, Synaptic modification by correlated activity: Hebb's postulate revisited. Annu. Rev. Neurosci. 24, 139-166 (2001).
-
(2001)
Annu. Rev. Neurosci.
, vol.24
, pp. 139-166
-
-
Bi, G.1
Poo, M.2
-
55
-
-
65549123471
-
HDAC2 negatively regulates memory formation and synaptic plasticity
-
J. S. Guan, S. J. Haggarty, E. Giacometti, J. H. Dannenberg, N. Joseph, J. Gao, T. J. Nieland, Y. Zhou, X. Wang, R. Mazitschek, J. E. Bradner, R. A. De Pinho, R. Jaenisch, L. H. Tsai, HDAC2 negatively regulates memory formation and synaptic plasticity. Nature 459, 55-60 (2009).
-
(2009)
Nature
, vol.459
, pp. 55-60
-
-
Guan, J.S.1
Haggarty, S.J.2
Giacometti, E.3
Dannenberg, J.H.4
Joseph, N.5
Gao, J.6
Nieland, T.J.7
Zhou, Y.8
Wang, X.9
Mazitschek, R.10
Bradner, J.E.11
De Pinho, R.A.12
Jaenisch, R.13
Tsai, L.H.14
-
56
-
-
5344241223
-
LTP and LTD: An embarrassment of riches
-
R. C. Malenka, M. F. Bear, LTP and LTD: An embarrassment of riches. Neuron 44, 5-21 (2004).
-
(2004)
Neuron
, vol.44
, pp. 5-21
-
-
Malenka, R.C.1
Bear, M.F.2
-
57
-
-
84861189663
-
Epigenetic regulation of reelin and brain-derived neurotrophic factor genes in long-term potentiation in rat medial prefrontal cortex
-
L. Sui, Y. Wang, L. H. Ju, M. Chen, Epigenetic regulation of reelin and brain-derived neurotrophic factor genes in long-term potentiation in rat medial prefrontal cortex. Neurobiol. Learn. Mem. 97, 425-440 (2012).
-
(2012)
Neurobiol. Learn. Mem.
, vol.97
, pp. 425-440
-
-
Sui, L.1
Wang, Y.2
Ju, L.H.3
Chen, M.4
-
58
-
-
55049136860
-
Strength through diversity
-
S. B. Nelson, G. G. Turrigiano, Strength through diversity. Neuron 60, 477-482 (2008).
-
(2008)
Neuron
, vol.60
, pp. 477-482
-
-
Nelson, S.B.1
Turrigiano, G.G.2
-
59
-
-
84866432385
-
MSK1 regulates homeostatic and experience-dependent synaptic plasticity
-
S. A. Corrêa, C. J. Hunter, O. Palygin, S. C. Wauters, K. J. Martin, C. McKenzie, K. McKelvey, R. G. Morris, Y. Pankratov, J. S. Arthur, B. G. Frenguelli, MSK1 regulates homeostatic and experience-dependent synaptic plasticity. J. Neurosci. 32, 13039-13051 (2012).
-
(2012)
J. Neurosci.
, vol.32
, pp. 13039-13051
-
-
Corrêa, S.A.1
Hunter, C.J.2
Palygin, O.3
Wauters, S.C.4
Martin, K.J.5
McKenzie, C.6
McKelvey, K.7
Morris, R.G.8
Pankratov, Y.9
Arthur, J.S.10
Frenguelli, B.G.11
-
60
-
-
33645882216
-
MeCP2-dependent transcriptional repression regulates excitatory neurotransmission
-
E. D. Nelson, E. T. Kavalali, L. M. Monteggia, MeCP2-dependent transcriptional repression regulates excitatory neurotransmission. Curr. Biol. 16, 710-716 (2006).
-
(2006)
Curr. Biol.
, vol.16
, pp. 710-716
-
-
Nelson, E.D.1
Kavalali, E.T.2
Monteggia, L.M.3
-
61
-
-
84862908227
-
The Rett syndrome protein MeCP2 regulates synaptic scaling
-
Z. Qiu, E. L. Sylwestrak, D. N. Lieberman, Y. Zhang, X. Y. Liu, A. Ghosh, The Rett syndrome protein MeCP2 regulates synaptic scaling. J. Neurosci. 32, 989-994 (2012).
-
(2012)
J. Neurosci.
, vol.32
, pp. 989-994
-
-
Qiu, Z.1
Sylwestrak, E.L.2
Lieberman, D.N.3
Zhang, Y.4
Liu, X.Y.5
Ghosh, A.6
-
62
-
-
45249121770
-
Synapse-specific adaptations to inactivity in hippocampal circuits achieve homeostatic gain control while dampening network reverberation
-
J. Kim, R. W. Tsien, Synapse-specific adaptations to inactivity in hippocampal circuits achieve homeostatic gain control while dampening network reverberation. Neuron 58, 925-937 (2008).
-
(2008)
Neuron
, vol.58
, pp. 925-937
-
-
Kim, J.1
Tsien, R.W.2
-
63
-
-
84872175082
-
Mossy fiber-CA3 synapses mediate homeostatic plasticity in mature hippocampal neurons
-
K. J. Lee, B. N. Queenan, A. M. Rozeboom, R. Bellmore, S. T. Lim, S. Vicini, D. T. Pak, Mossy fiber-CA3 synapses mediate homeostatic plasticity in mature hippocampal neurons. Neuron 77, 99-114 (2013).
-
(2013)
Neuron
, vol.77
, pp. 99-114
-
-
Lee, K.J.1
Queenan, B.N.2
Rozeboom, A.M.3
Bellmore, R.4
Lim, S.T.5
Vicini, S.6
Pak, D.T.7
-
64
-
-
83355171133
-
Homeostatic regulation of AMPA receptor trafficking and degradation by light-controlled single-synaptic activation
-
Q. Hou, J. Gilbert, H. Y. Man, Homeostatic regulation of AMPA receptor trafficking and degradation by light-controlled single-synaptic activation. Neuron 72, 806-818 (2011).
-
(2011)
Neuron
, vol.72
, pp. 806-818
-
-
Hou, Q.1
Gilbert, J.2
Man, H.Y.3
-
65
-
-
77953951999
-
Metaplasticity at single glutamatergic synapses
-
M. C. Lee, R. Yasuda, M. D. Ehlers, Metaplasticity at single glutamatergic synapses. Neuron 66, 859-870 (2010).
-
(2010)
Neuron
, vol.66
, pp. 859-870
-
-
Lee, M.C.1
Yasuda, R.2
Ehlers, M.D.3
-
66
-
-
84902282655
-
Methamphetamine downregulates striatal glu-tamate receptors via diverse epigenetic mechanisms
-
S. Jayanthi, M. T. McCoy, B. Chen, J. P. Britt, S. Kourrich, H. J. Yau, B. Ladenheim, I. N. Krasnova, A. Bonci, J. L. Cadet, Methamphetamine downregulates striatal glu-tamate receptors via diverse epigenetic mechanisms. Biol. Psychiatry 76, 47-56 (2014).
-
(2014)
Biol. Psychiatry
, vol.76
, pp. 47-56
-
-
Jayanthi, S.1
McCoy, M.T.2
Chen, B.3
Britt, J.P.4
Kourrich, S.5
Yau, H.J.6
Ladenheim, B.7
Krasnova, I.N.8
Bonci, A.9
Cadet, J.L.10
-
67
-
-
0035873225
-
Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription
-
F. Fuks, W. A. Burgers, N. Godin, M. Kasai, T. Kouzarides, Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription. EMBO J. 20, 2536-2544 (2001).
-
(2001)
EMBO J.
, vol.20
, pp. 2536-2544
-
-
Fuks, F.1
Burgers, W.A.2
Godin, N.3
Kasai, M.4
Kouzarides, T.5
-
68
-
-
0026439115
-
-
H. Leonhardt, A. W. Page, H. U. Weier, T. H. Bestor, A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell 71, 865-873 (1992).
-
(1992)
A Targeting Sequence Directs DNA Methyltransferase to Sites of DNA Replication in Mammalian Nuclei. Cell
, vol.71
, pp. 865-873
-
-
Leonhardt, H.1
Page, A.W.2
Weier, H.U.3
Bestor, T.H.4
-
69
-
-
0036683055
-
Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyl-transferases
-
G. D. Kim, J. Ni, N. Kelesoglu, R. J. Roberts, S. Pradhan, Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyl-transferases. EMBO J. 21, 4183-4195 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 4183-4195
-
-
Kim, G.D.1
Ni, J.2
Kelesoglu, N.3
Roberts, R.J.4
Pradhan, S.5
-
70
-
-
84873038036
-
Chronic inactivation of a neural circuit enhances LTP by inducing silent synapse formation
-
K. L. Arendt, F. Sarti, L. Chen, Chronic inactivation of a neural circuit enhances LTP by inducing silent synapse formation. J. Neurosci. 33, 2087-2096 (2013).
-
(2013)
J. Neurosci.
, vol.33
, pp. 2087-2096
-
-
Arendt, K.L.1
Sarti, F.2
Chen, L.3
-
71
-
-
33746621248
-
Homeostatic shutdown of long-term potentiation in the adult hippocampus
-
C. Roth-Alpermann, R. G. Morris, M. Korte, T. Bonhoeffer, Homeostatic shutdown of long-term potentiation in the adult hippocampus. Proc. Natl. Acad. Sci. U. S. A. 103, 11039-11044 (2006).
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 11039-11044
-
-
Roth-Alpermann, C.1
Morris, R.G.2
Korte, M.3
Bonhoeffer, T.4
-
72
-
-
33845865244
-
LTP and adaptation to inactivity: Overlapping mechanisms and implications for metaplasticity
-
T. C. Thiagarajan, M. Lindskog, A. Malgaroli, R. W. Tsien, LTP and adaptation to inactivity: Overlapping mechanisms and implications for metaplasticity. Neuropharmacology 52, 156-175 (2007).
-
(2007)
Neuropharmacology
, vol.52
, pp. 156-175
-
-
Thiagarajan, T.C.1
Lindskog, M.2
Malgaroli, A.3
Tsien, R.W.4
-
73
-
-
48449105928
-
IDT SciTools: A suite for analysis and design of nucleic acid oligomers
-
R. Owczarzy, A. V. Tataurov, Y. Wu, J. A. Manthey, K. A. McQuisten, H. G. Almabrazi, K. F. Pedersen, Y. Lin, J. Garretson, N. O. McEntaggart, C. A. Sailor, R. B. Dawson, A. S. Peek, IDT SciTools: A suite for analysis and design of nucleic acid oligomers. Nucleic Acids Res. 36, W163-W169 (2008).
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. W163-W169
-
-
Owczarzy, R.1
Tataurov, A.V.2
Wu, Y.3
Manthey, J.A.4
McQuisten, K.A.5
Almabrazi, H.G.6
Pedersen, K.F.7
Lin, Y.8
Garretson, J.9
McEntaggart, N.O.10
Sailor, C.A.11
Dawson, R.B.12
Peek, A.S.13
-
75
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
M. W. Pfaffl, A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29, e45 (2001).
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. e45
-
-
Pfaffl, M.W.1
|