-
1
-
-
13344285339
-
Identification and characterization of a new member of the TNF family that induces apoptosis
-
Wiley SR, Schooley K, Smolak PJ, Din WS, Huang CP, Nicholl JK et al. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 1995; 3: 673-682.
-
(1995)
Immunity
, vol.3
, pp. 673-682
-
-
Wiley, S.R.1
Schooley, K.2
Smolak, P.J.3
Din, W.S.4
Huang, C.P.5
Nicholl, J.K.6
-
2
-
-
17544367410
-
Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
-
Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, Ashkenazi A. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem 1996; 271: 12687-12690.
-
(1996)
J Biol Chem
, vol.271
, pp. 12687-12690
-
-
Pitti, R.M.1
Marsters, S.A.2
Ruppert, S.3
Donahue, C.J.4
Moore, A.5
Ashkenazi, A.6
-
3
-
-
77953707447
-
TRAIL and other TRAIL receptor agonists as novel cancer therapeutics
-
Falschlehner C, Ganten TM, Koschny R, Schaefer U, Walczak H. TRAIL and other TRAIL receptor agonists as novel cancer therapeutics. Adv Exp Med Biol 2009; 647: 195-206.
-
(2009)
Adv Exp Med Biol
, vol.647
, pp. 195-206
-
-
Falschlehner, C.1
Ganten, T.M.2
Koschny, R.3
Schaefer, U.4
Walczak, H.5
-
4
-
-
0032929520
-
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
-
Walczak H, Miller RE, Ariail K, Gliniak B, Griffith TS, Kubin M et al. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med 1999; 5: 157-163.
-
(1999)
Nat Med
, vol.5
, pp. 157-163
-
-
Walczak, H.1
Miller, R.E.2
Ariail, K.3
Gliniak, B.4
Griffith, T.S.5
Kubin, M.6
-
5
-
-
0030880548
-
TRAILR2: A novel apoptosis-mediating receptor for TRAIL
-
Walczak H, Degli-Esposti MA, Johnson RS, Smolak PJ, Waugh JY, Boiani N et al. TRAILR2: a novel apoptosis-mediating receptor for TRAIL. EMBO J 1997; 16: 5386-5397.
-
(1997)
EMBO J
, vol.16
, pp. 5386-5397
-
-
Walczak, H.1
Degli-Esposti, M.A.2
Johnson, R.S.3
Smolak, P.J.4
Waugh, J.Y.5
Boiani, N.6
-
6
-
-
0030996297
-
The receptor for the cytotoxic ligand TRAIL
-
Pan G, O'Rourke K, Chinnaiyan AM, Gentz R, Ebner R, Ni J et al. The receptor for the cytotoxic ligand TRAIL. Science 1997; 276: 111-113.
-
(1997)
Science
, vol.276
, pp. 111-113
-
-
Pan, G.1
O'Rourke, K.2
Chinnaiyan, A.M.3
Gentz, R.4
Ebner, R.5
Ni, J.6
-
7
-
-
77956170550
-
New insights into apoptosis signaling by Apo2L/TRAIL
-
Gonzalvez F, Ashkenazi A. New insights into apoptosis signaling by Apo2L/TRAIL. Oncogene 2010; 29: 4752-4765.
-
(2010)
Oncogene
, vol.29
, pp. 4752-4765
-
-
Gonzalvez, F.1
Ashkenazi, A.2
-
8
-
-
0031239984
-
TRICK2 a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL
-
Screaton GR, Mongkolsapaya J, Xu XN, Cowper AE, McMichael AJ, JI Bell. TRICK2 a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL. Curr Biol 1997; 7: 693-696.
-
(1997)
Curr Biol
, vol.7
, pp. 693-696
-
-
Screaton, G.R.1
Mongkolsapaya, J.2
Xu, X.N.3
Cowper, A.E.4
McMichael, A.J.5
Bell, J.I.6
-
10
-
-
33746359639
-
The death-associated protein kinases: Structure, function, and beyond
-
Bialik S, Kimchi A. The death-associated protein kinases: structure, function, and beyond. Annu Rev Biochemis 2006; 75: 189-210.
-
(2006)
Annu Rev Biochemis
, vol.75
, pp. 189-210
-
-
Bialik, S.1
Kimchi, A.2
-
11
-
-
34249314024
-
Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia
-
Raval A, Tanner SM, Byrd JC, Angerman EB, Perko JD, Chen SS et al. Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia. Cell 2007; 129: 879-890.
-
(2007)
Cell
, vol.129
, pp. 879-890
-
-
Raval, A.1
Tanner, S.M.2
Byrd, J.C.3
Angerman, E.B.4
Perko, J.D.5
Chen, S.S.6
-
12
-
-
0033542380
-
Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity
-
Kawai T, Nomura F, Hoshino K, Copeland NG, Gilbert DJ, Jenkins NA et al. Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity. Oncogene 1999; 18: 3471-3480.
-
(1999)
Oncogene
, vol.18
, pp. 3471-3480
-
-
Kawai, T.1
Nomura, F.2
Hoshino, K.3
Copeland, N.G.4
Gilbert, D.J.5
Jenkins, N.A.6
-
13
-
-
0033960235
-
Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis
-
Inbal B, Shani G, Cohen O, Kissil JL, Kimchi A. Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis. Mol Cell Biol 2000; 20: 1044-1054.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 1044-1054
-
-
Inbal, B.1
Shani, G.2
Cohen, O.3
Kissil, J.L.4
Kimchi, A.5
-
14
-
-
0037193474
-
DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death
-
Inbal B, Bialik S, Sabanay I, Shani G, Kimchi A. DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death. J Cell Biol 2002; 157: 455-468.
-
(2002)
J Cell Biol
, vol.157
, pp. 455-468
-
-
Inbal, B.1
Bialik, S.2
Sabanay, I.3
Shani, G.4
Kimchi, A.5
-
15
-
-
84899630089
-
Control of gp130 expression by the mitogen-activated protein kinase ERK2
-
Bonito NA, Drechsler J, Stoecker S, Carmo CR, Seckl MJ, Hermanns HM et al. Control of gp130 expression by the mitogen-activated protein kinase ERK2. Oncogene 2014; 33: 2255-2263.
-
(2014)
Oncogene
, vol.33
, pp. 2255-2263
-
-
Bonito, N.A.1
Drechsler, J.2
Stoecker, S.3
Carmo, C.R.4
Seckl, M.J.5
Hermanns, H.M.6
-
17
-
-
0030869432
-
Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family
-
Degli-Esposti MA, Smolak PJ, Walczak H, Waugh J, Huang CP, DuBose RF et al. Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family. J Exp Med 1997; 186: 1165-1170.
-
(1997)
J Exp Med
, vol.186
, pp. 1165-1170
-
-
Degli-Esposti, M.A.1
Smolak, P.J.2
Walczak, H.3
Waugh, J.4
Huang, C.P.5
Dubose, R.F.6
-
18
-
-
7344233085
-
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL
-
Emery JG, McDonnell P, Burke MB, Deen KC, Lyn S, Silverman C et al. Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. J Biol Chem 1998; 273: 14363-14367.
-
(1998)
J Biol Chem
, vol.273
, pp. 14363-14367
-
-
Emery, J.G.1
McDonnell, P.2
Burke, M.B.3
Deen, K.C.4
Lyn, S.5
Silverman, C.6
-
19
-
-
20744433491
-
Transcription factor NF-kappaB differentially regulates death receptor 5 expression involving histone deacetylase 1
-
Shetty S, Graham BA, Brown JG, Hu X, Vegh-Yarema N, Harding G et al. Transcription factor NF-kappaB differentially regulates death receptor 5 expression involving histone deacetylase 1. Mol Cell Biol 2005; 25: 5404-5416.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 5404-5416
-
-
Shetty, S.1
Graham, B.A.2
Brown, J.G.3
Hu, X.4
Vegh-Yarema, N.5
Harding, G.6
-
20
-
-
4344607589
-
Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs
-
Ganten TM, Haas TL, Sykora J, Stahl H, Sprick MR, Fas SC et al. Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs. Cell Death Differen 2004; 11(Suppl 1): S86-S96.
-
(2004)
Cell Death Differen
, vol.11
, pp. S86-S96
-
-
Ganten, T.M.1
Haas, T.L.2
Sykora, J.3
Stahl, H.4
Sprick, M.R.5
Fas, S.C.6
-
21
-
-
11144230279
-
Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells
-
Sinicrope FA, Penington RC, Tang XM. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells. Clin Cancer Res 2004; 10: 8284-8292.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8284-8292
-
-
Sinicrope, F.A.1
Penington, R.C.2
Tang, X.M.3
-
22
-
-
42349098051
-
BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells
-
Huang S, Sinicrope FA. BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells. Cancer Res 2008; 68: 2944-2951.
-
(2008)
Cancer Res
, vol.68
, pp. 2944-2951
-
-
Huang, S.1
Sinicrope, F.A.2
-
23
-
-
49849089793
-
Proteasome inhibitor PS-341 (VELCADE) induces stabilization of the TRAIL receptor DR5 mRNA through the 3'-untranslated region
-
Kandasamy K, Kraft AS. Proteasome inhibitor PS-341 (VELCADE) induces stabilization of the TRAIL receptor DR5 mRNA through the 3'-untranslated region. Mol Cancer Therap 2008; 7: 1091-1100.
-
(2008)
Mol Cancer Therap
, vol.7
, pp. 1091-1100
-
-
Kandasamy, K.1
Kraft, A.S.2
-
24
-
-
44149118847
-
Death receptor-4 (DR4) expression is regulated by transcription factor NF-kappaB in response to etoposide treatment
-
Mendoza FJ, Ishdorj G, Hu X, Gibson SB. Death receptor-4 (DR4) expression is regulated by transcription factor NF-kappaB in response to etoposide treatment. Apoptosis 2008; 13: 756-770.
-
(2008)
Apoptosis
, vol.13
, pp. 756-770
-
-
Mendoza, F.J.1
Ishdorj, G.2
Hu, X.3
Gibson, S.B.4
-
25
-
-
0035920230
-
Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1
-
Bernard D, Quatannens B, Vandenbunder B, Abbadie C. Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1. J Biol Chem 2001; 276: 27322-27328.
-
(2001)
J Biol Chem
, vol.276
, pp. 27322-27328
-
-
Bernard, D.1
Quatannens, B.2
Vandenbunder, B.3
Abbadie, C.4
-
26
-
-
19944432895
-
NFkappaB-mediated upregulation of bcl-xl restrains TRAIL-mediated apoptosis in murine viral hepatitis
-
Zender L, Hutker S, Mundt B, Waltemathe M, Klein C, Trautwein C et al. NFkappaB-mediated upregulation of bcl-xl restrains TRAIL-mediated apoptosis in murine viral hepatitis. Hepatology 2005; 41: 280-288.
-
(2005)
Hepatology
, vol.41
, pp. 280-288
-
-
Zender, L.1
Hutker, S.2
Mundt, B.3
Waltemathe, M.4
Klein, C.5
Trautwein, C.6
-
27
-
-
0031414749
-
The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAILmediated apoptosis, yet retains an incomplete death domain
-
Degli-Esposti MA, Dougall WC, Smolak PJ, Waugh JY, Smith CA, Goodwin RG. The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAILmediated apoptosis, yet retains an incomplete death domain. Immunity 1997; 7: 813-820.
-
(1997)
Immunity
, vol.7
, pp. 813-820
-
-
Degli-Esposti, M.A.1
Dougall, W.C.2
Smolak, P.J.3
Waugh, J.Y.4
Smith, C.A.5
Goodwin, R.G.6
-
28
-
-
33745342580
-
NFkappaB pathway: A good signaling paradigm and therapeutic target
-
Tergaonkar V. NFkappaB pathway: a good signaling paradigm and therapeutic target. Int J Bioch Cell Biol 2006; 38: 1647-1653.
-
(2006)
Int J Bioch Cell Biol
, vol.38
, pp. 1647-1653
-
-
Tergaonkar, V.1
-
29
-
-
84859982175
-
DAPk1 inhibits NF-kappaB activation through TNF-alpha and INF-gamma-induced apoptosis
-
Yoo HJ, Byun HJ, Kim BR, Lee KH, Park SY, Rho SB. DAPk1 inhibits NF-kappaB activation through TNF-alpha and INF-gamma-induced apoptosis. Cell Signal 2012; 24: 1471-1477.
-
(2012)
Cell Signal
, vol.24
, pp. 1471-1477
-
-
Yoo, H.J.1
Byun, H.J.2
Kim, B.R.3
Lee, K.H.4
Park, S.Y.5
Rho, S.B.6
-
30
-
-
49149091747
-
The tumor suppressor deathassociated protein kinase targets to TCR-stimulated NF-kappa B activation
-
Chuang YT, Fang LW, Lin-Feng MH, Chen RH, Lai MZ. The tumor suppressor deathassociated protein kinase targets to TCR-stimulated NF-kappa B activation. J Immunol 2008; 180: 3238-3249.
-
(2008)
J Immunol
, vol.180
, pp. 3238-3249
-
-
Chuang, Y.T.1
Fang, L.W.2
Lin-Feng, M.H.3
Chen, R.H.4
Lai, M.Z.5
-
31
-
-
33645932601
-
DAPk protein family and cancer
-
Gozuacik D, Kimchi A. DAPk protein family and cancer. Autophagy 2006; 2: 74-79.
-
(2006)
Autophagy
, vol.2
, pp. 74-79
-
-
Gozuacik, D.1
Kimchi, A.2
-
32
-
-
0033667778
-
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
-
Sprick MR, Weigand MA, Rieser E, Rauch CT, Juo P, Blenis J et al. FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. Immunity 2000; 12: 599-609.
-
(2000)
Immunity
, vol.12
, pp. 599-609
-
-
Sprick, M.R.1
Weigand, M.A.2
Rieser, E.3
Rauch, C.T.4
Juo, P.5
Blenis, J.6
|