CCR1 plays a critical role in modulating pain through hematopoietic and non-hematopoietic cells

PLoS ONE

Volumn 9, Issue 8, 2014, Pages

  Lewis, Nuruddeen D ^a   Muthukumarana, Akalushi ^a   Fogal, Steven E ^a   Corradini, Laura ^b   Stefanopoulos, Dimitria E ^a   Adusumalli, Prathima ^a   Pelletier, Josephine ^a   Panzenbeck, Mark ^a   Berg, Karen ^a   Canfield, Melissa ^a   Cook, Brian N ^a   Razavi, Hossein ^a   Kuzmich, Daniel ^a   Anderson, Shawn ^a   Allard, Devan ^a   Harrison, Paul ^a   Grimaldi, Christine ^a   Souza, Donald ^a   Harcken, Christian ^a   Fryer, Ryan M ^a   Modis, Louise K ^a   Brown, Maryanne L ^a   more..

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; BI 33; BI 64; CHEMOKINE RECEPTOR ANTAGONIST; CHEMOKINE RECEPTOR CCR1; INDOMETACIN; UNCLASSIFIED DRUG; CCR1 PROTEIN, MOUSE; FREUND ADJUVANT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; HEMATOPOIETIC CELL; HYPERALGESIA; IC 50; IN VIVO STUDY; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PAIN; PERITONITIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; WRITHING TEST; ANIMAL; ANTAGONISTS AND INHIBITORS; BONE MARROW TRANSPLANTATION; C57BL MOUSE; CELL MOTION; CHEMICALLY INDUCED; EXPERIMENTAL ARTHRITIS; FLOW CYTOMETRY; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; LEUKOCYTE; METABOLISM; NEUTROPHIL; PAIN MEASUREMENT; PROCEDURES;

ACETIC ACID; ANIMALS; ARTHRITIS, EXPERIMENTAL; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CELL MOVEMENT; FLOW CYTOMETRY; FREUND'S ADJUVANT; HYPERALGESIA; LEUKOCYTES; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID CELLS; NEUTROPHIL INFILTRATION; NEUTROPHILS; PAIN; PAIN MEASUREMENT; PERITONITIS; RECEPTORS, CCR1;

EID: 84932172409     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0105883     Document Type: Article

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