Oxymatrine improves intestinal epithelial barrier function involving NF-κB-mediated signaling pathway in CCl4-induced cirrhotic rats

PLoS ONE

Volumn 9, Issue 8, 2014, Pages

  Wen, Jian Bo ^a   Zhu, Fang Qing ^a   Chen, Wei Guo ^a   Jiang, Li Ping ^a   Chen, Jie ^a   Hu, Zhao Peng ^a   Huang, Yong Jian ^a   Zhou, Zhi Wei ^b   Wang, Gui Liang ^a   Lin, Hao ^a   Zhou, Shu Feng ^b  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; OXYMATRINE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; ALKALOID; CARBON TETRACHLORIDE; PROTECTIVE AGENT; QUINOLIZINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD LEVEL; CELL INFILTRATION; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HISTOPATHOLOGY; IL 6 GENE; IMMUNOHISTOCHEMISTRY; INTESTINAL EPITHELIAL BARRIER; INTESTINE EPITHELIUM; INTESTINE FUNCTION; INTESTINE INJURY; INTESTINE MUCOSA PERMEABILITY; INTESTINE VILLUS; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TISSUE STRUCTURE; TNF ALPHA GENE; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; CHEMICALLY INDUCED; DRUG EFFECTS; GENETICS; INTESTINE; INTESTINE MUCOSA; LIVER CIRRHOSIS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; RANDOMIZATION; SPRAGUE DAWLEY RAT;

ALKALOIDS; ANIMALS; CARBON TETRACHLORIDE; ENDOTOXINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-6; INTESTINAL MUCOSA; INTESTINES; LIVER CIRRHOSIS; MALE; PROTECTIVE AGENTS; QUINOLIZINES; RANDOM ALLOCATION; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84932111784     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106082     Document Type: Article

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