Genome-wide mutagenesis of influenza virus reveals unique plasticity of the hemagglutinin and NS1 proteins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 50, 2013, Pages 20248-20253

  Heaton, Nicholas S ^a   Sachs, David ^a   Chen, Chi Jene ^a   Hai, Rong ^a   Palese, Peter ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Insertional mutagenesis; Protein flexibility; Viral evolution

Indexed keywords

NONSTRUCTURAL PROTEIN 1; SCAFFOLD PROTEIN; VIRUS HEMAGGLUTININ; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; BACTERIOPHAGE MU; CONTROLLED STUDY; DNA VECTOR; GENETIC TRANSFECTION; HOST RANGE; IN VITRO STUDY; INFLUENZA VIRUS A; INFLUENZA VIRUS A H1N1; INNATE IMMUNITY; MDCK CELL; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASTICITY; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOP CODON; TRANSPOSON; VIRUS ATTENUATION; VIRUS GENOME; VIRUS MUTANT; VIRUS MUTATION; VIRUS PARTICLE; VIRUS RECOMBINANT;

EID: 84890281675     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1320524110     Document Type: Article

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