Quantitative analysis of low-abundance serological proteins with peptide affinity-based enrichment and pseudo-multiple reaction monitoring by hybrid quadrupole time-of-flight mass spectrometry

Analytica Chimica Acta

Volumn 882, Issue , 2015, Pages 38-48

  Kim, Kwang Hoe ^a,c   Ahn, Yeong Hee ^b   Ji, Eun Sun ^a   Lee, Ju Yeon ^a   Kim, Jin Young ^a   An, Hyun Joo ^c   Yoo, Jong Shin ^a,c  

^a Korea Basic Science Institute (KBSI)   (South Korea)

^b Chongju University   (South Korea)

^c Chungnam National University   (South Korea)

Author keywords

Hybrid quadrupole time of flight mass spectrometer; Low abundance serological protein; Peptide affinity based enrichment; Pseudo multiple reaction monitoring

Indexed keywords

AMINO ACIDS; DISEASES; INDUCTIVELY COUPLED PLASMA; MASS SPECTROMETERS; MASS SPECTROMETRY; SIGNAL TO NOISE RATIO; TISSUE;

COEFFICIENTS OF VARIATIONS; MULTIPLE REACTION MONITORING; MULTIPLE TRANSITIONS; PROTEIN-TYROSINE PHOSPHATASE; QUADRUPOLE TIME OF FLIGHT MASS SPECTROMETRY; QUADRUPOLE-TIME OF FLIGHTS; QUADRUPOLE-TIME-OF-FLIGHT MASS SPECTROMETER; SIGNAL TO NOISE (S/N) RATIOS;

PEPTIDES;

PROTEIN; PROTEIN TYROSINE PHOSPHATASE; SYNTHETIC PEPTIDE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE TYPE PROTEIN TYROSINE PHOSPHATASE KAPPA; UNCLASSIFIED DRUG; AFFINITY LABELING; PEPTIDE; PLASMA PROTEIN;

ANALYTIC METHOD; ARTICLE; COLORECTAL CANCER; HUMAN; HYBRID QUADRUPOLE TIME OF FLIGHT MASS SPECTROMETRY; MULTIPLE REACTION MONITORING; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; SENSITIVITY ANALYSIS; SIGNAL NOISE RATIO; TIME OF FLIGHT MASS SPECTROMETRY; AFFINITY LABELING; AMINO ACID SEQUENCE; CALIBRATION; CHEMISTRY; LIMIT OF DETECTION; MOLECULAR GENETICS; PROCEDURES; TANDEM MASS SPECTROMETRY;

AFFINITY LABELS; AMINO ACID SEQUENCE; BLOOD PROTEINS; CALIBRATION; HUMANS; LIMIT OF DETECTION; MOLECULAR SEQUENCE DATA; PEPTIDES; TANDEM MASS SPECTROMETRY;

EID: 84931566676     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2015.04.033     Document Type: Article

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