Impacts of enterotoxin gene cluster-encoded superantigens on local and systemic experimental Staphylococcus aureus infections

European Journal of Clinical Microbiology and Infectious Diseases

Volumn 34, Issue 7, 2015, Pages 1443-1449

  Nowrouzian, F L ^a   Ali, A ^a   Badiou, C ^b   Dauwalder, O ^b   Lina, G ^b   Josefsson, E ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b CENTRE INTERNATIONAL DE RECHERCHE EN INFECTIOLOGIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; SEG PROTEIN; SELM PROTEIN; SELO PROTEIN; STAPHYLOCOCCUS ENTEROTOXIN; SUPERANTIGEN; UNCLASSIFIED DRUG; ENTEROTOXIN; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BACTERIOPHAGE; CONTROLLED STUDY; EXPERIMENTAL INFECTION; FEMALE; GENE CLUSTER; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN INFECTION; SOFT TISSUE INFECTION; STAPHYLOCOCCUS INFECTION; WEIGHT REDUCTION; ANIMAL; BACTERIAL GENE; DISEASE MODEL; GENE EXPRESSION REGULATION; GENE LOCUS; GENETICS; HUMAN; METABOLISM; MICROBIOLOGY; MULTIGENE FAMILY; MUTATION; PATHOGENICITY; PATHOLOGY; STAPHYLOCOCCUS AUREUS;

ANIMALS; DISEASE MODELS, ANIMAL; ENTEROTOXINS; FEMALE; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; GENETIC LOCI; HUMANS; MICE; MULTIGENE FAMILY; MUTATION; RNA, MESSENGER; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; SUPERANTIGENS;

EID: 84931564893     PISSN: 09349723     EISSN: 14354373     Source Type: Journal    
DOI: 10.1007/s10096-015-2371-4     Document Type: Article

References (33)

1. Aniansson G, Alm B, Andersson B, Larsson P, Nylén O, Peterson H et al (1992) Nasopharyngeal colonization during the first year of life. J Infect Dis 165(Suppl 1):S38–S42
2. Lindberg E, Nowrouzian F, Adlerberth I, Wold AE (2000) Long-time persistence of superantigen-producing Staphylococcus aureus strains in the intestinal microflora of healthy infants. Pediatr Res 48:741–747
3. Lowy FD (1998) Staphylococcus aureus infections. N Engl J Med 339:520–532
4. Deringer JR, Ely RJ, Stauffacher CV, Bohach GA (1996) Subtype-specific interactions of type C staphylococcal enterotoxins with the T-cell receptor. Mol Microbiol 22:523–534
5. Dinges MM, Orwin PM, Schlievert PM (2000) Exotoxins of Staphylococcus aureus. Clin Microbiol Rev 13:16–34
6. Lina G, Bohach GA, Nair SP, Hiramatsu K, Jouvin-Marche E, Mariuzza R; International Nomenclature Committee for Staphylococcal Superantigens (2004) Standard nomenclature for the superantigens expressed by Staphylococcus. J Infect Dis 189:2334–2336
7. Jarraud S, Peyrat MA, Lim A, Tristan A, Bes M, Mougel C et al (2001) egc, a highly prevalent operon of enterotoxin gene, forms a putative nursery of superantigens in Staphylococcus aureus. J Immunol 166:669–677
8. Cretenet M, Even S, Le Loir Y (2011) Unveiling Staphylococcus aureus enterotoxin production in dairy products: a review of recent advances to face new challenges. Dairy Sci Technol 91:127–150
9. Blaiotta G, Fusco V, von Eiff C, Villani F, Becker K (2006) Biotyping of enterotoxigenic Staphylococcus aureus by enterotoxin gene cluster (egc) polymorphism and spa typing analyses. Appl Environ Microbiol 72:6117–6123
10. Becker K, Friedrich AW, Peters G, von Eiff C (2004) Systematic survey on the prevalence of genes coding for staphylococcal enterotoxins SElM, SElO, and SElN. Mol Nutr Food Res 48:488–495
11. Nowrouzian FL, Dauwalder O, Meugnier H, Bes M, Etienne J, Vandenesch F et al (2011) Adhesin and superantigen genes and the capacity of Staphylococcus aureus to colonize the infantile gut. J Infect Dis 204:714–721
12. Ferry T, Thomas D, Genestier AL, Bes M, Lina G, Vandenesch F et al (2005) Comparative prevalence of superantigen genes in Staphylococcus aureus isolates causing sepsis with and without septic shock. Clin Infect Dis 41:771–777
13. Baba T, Bae T, Schneewind O, Takeuchi F, Hiramatsu K (2008) Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes: polymorphism and evolution of two major pathogenicity islands. J Bacteriol 190:300–310
14. Luong TT, Lee CY (2007) Improved single-copy integration vectors for Staphylococcus aureus. J Microbiol Methods 70:186–190
15. Holden MT, Feil EJ, Lindsay JA, Peacock SJ, Day NP, Enright MC et al (2004) Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance. Proc Natl Acad Sci U S A 101:9786–9791
16. Collery MM, Smyth DS, Tumilty JJ, Twohig JM, Smyth CJ (2009) Associations between enterotoxin gene cluster types egc1, egc2 and egc3, agr types, enterotoxin and enterotoxin-like gene profiles, and molecular typing characteristics of human nasal carriage and animal isolates of Staphylococcus aureus. J Med Microbiol 58:13–25
17. Williams P, Ketley J, Salmond G (eds) (1998) Bacterial pathogenesis, vol 27. Academic Press, San Diego
18. Derzelle S, Dilasser F, Duquenne M, Deperrois V (2009) Differential temporal expression of the staphylococcal enterotoxins genes during cell growth. Food Microbiol 26:896–904
19. Nowrouzian FL, Monstein HJ, Wold AE, Adlerberth I (2005) Effect of human milk on type 1 and P-fimbrial mRNA expression in intestinal Escherichia coli strains. Lett Appl Microbiol 40:74–80
20. Lee YD, Moon BY, Park JH, Chang HI, Kim WJ (2007) Expression of enterotoxin genes in Staphylococcus aureus isolates based on mRNA analysis. J Microbiol Biotechnol 17:461–467
21. Lina G, Cozon G, Ferrandiz J, Greenland T, Vandenesch F, Etienne J (1998) Detection of staphylococcal superantigenic toxins by a CD69-specific cytofluorimetric assay measuring T-cell activation. J Clin Microbiol 36:1042–1045
22. Tseng CW, Zhang S, Stewart GC (2004) Accessory gene regulator control of staphyloccoccal enterotoxin d gene expression. J Bacteriol 186:1793–1801
23. Kwiecinski J, Jin T, Josefsson E (2014) Surface proteins of Staphylococcus aureus play an important role in experimental skin infection. APMIS 122:1240–1250
24. Bremell T, Lange S, Yacoub A, Rydén C, Tarkowski A (1991) Experimental Staphylococcus aureus arthritis in mice. Infect Immun 59:2615–2623
25. Josefsson E, Higgins J, Foster TJ, Tarkowski A (2008) Fibrinogen binding sites P336 and Y338 of clumping factor A are crucial for Staphylococcus aureus virulence. PLoS One 3:e2206
26. van Belkum A (2006) Staphylococcal colonization and infection: homeostasis versus disbalance of human (innate) immunity and bacterial virulence. Curr Opin Infect Dis 19:339–344
27. Karauzum H, Ferry T, de Bentzmann S, Lina G, Bes M, Vandenesch F et al (2008) Comparison of adhesion and virulence of two predominant hospital-acquired methicillin-resistant Staphylococcus aureus clones and clonal methicillin-susceptible S. aureus isolates. Infect Immun 76:5133–5138
28. Holtfreter S, Grumann D, Schmudde M, Nguyen HT, Eichler P, Strommenger B et al (2007) Clonal distribution of superantigen genes in clinical Staphylococcus aureus isolates. J Clin Microbiol 45:2669–2680
29. Abdelnour A, Bremell T, Tarkowski A (1994) Toxic shock syndrome toxin 1 contributes to the arthritogenicity of Staphylococcus aureus. J Infect Dis 170:94–99
30. Abdelnour A, Bremell T, Holmdahl R, Tarkowski A (1994) Clonal expansion of T lymphocytes causes arthritis and mortality in mice infected with toxic shock syndrome toxin-1-producing staphylococci. Eur J Immunol 24:1161–1166
31. Zhao YX, Abdelnour A, Kalland T, Tarkowski A (1995) Overexpression of the T-cell receptor V beta 3 in transgenic mice increases mortality during infection by enterotoxin A-producing Staphylococcus aureus. Infect Immun 63:4463–4469
32. Grumann D, Scharf SS, Holtfreter S, Kohler C, Steil L, Engelmann S et al (2008) Immune cell activation by enterotoxin gene cluster (egc)-encoded and non-egc superantigens from Staphylococcus aureus. J Immunol 181:5054–5061
33. Vasconcelos NG, Pereira VC, Araújo Júnior JP, da Cunha MdeL (2011) Molecular detection of enterotoxins E, G, H and I in Staphylococcus aureus and coagulase-negative staphylococci isolated from clinical samples of newborns in Brazil. J Appl Microbiol 111:749–762