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Volumn 5, Issue 1, 2015, Pages 51-63

Effects of pioglitazone or exercise in older adults with mild cognitive impairment and insulin resistance: A pilot study

Author keywords

Exercise; Insulin resistance; Mild cognitive impairment; Pioglitazone

Indexed keywords

OXYGEN; PIOGLITAZONE; PLACEBO;

EID: 84931460446     PISSN: None     EISSN: 16645464     Source Type: Journal    
DOI: 10.1159/000371509     Document Type: Article
Times cited : (31)

References (73)
  • 1
    • 79956084514 scopus 로고    scopus 로고
    • The diagnosis of mild cognitive impairment due to alzheimer's disease: Recommendations from the national institute on aging-alzheimer's association workgroups on diagnostic guidelines for alzheimer's disease
    • Albert MS, et al: The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 2011; 7: 270-279.
    • (2011) Alzheimers Dement , vol.7 , pp. 270-279
    • Albert, M.S.1
  • 2
    • 61849113222 scopus 로고    scopus 로고
    • Rate of progression of mild cognitive impairment to dementia-meta-analysis of 41 robust inception cohort studies
    • Mitchell AJ, Shiri-Feshki M: Rate of progression of mild cognitive impairment to dementia-meta-analysis of 41 robust inception cohort studies. Acta Psychiatr Scand 2009; 119: 252-265.
    • (2009) Acta Psychiatr Scand , vol.119 , pp. 252-265
    • Mitchell, A.J.1    Shiri-Feshki, M.2
  • 3
    • 56749159733 scopus 로고    scopus 로고
    • Temporal trends in the long term risk of progression of mild cognitive impairment: A pooled analysis
    • Mitchell AJ, Shiri-Feshki M: Temporal trends in the long term risk of progression of mild cognitive impairment: a pooled analysis. J Neurol Neurosurg Psychiatry 2008; 79: 1386-1391.
    • (2008) J Neurol Neurosurg Psychiatry , vol.79 , pp. 1386-1391
    • Mitchell, A.J.1    Shiri-Feshki, M.2
  • 4
    • 33747075424 scopus 로고    scopus 로고
    • Mild cognitive impairment: Risk of Alzheimer disease and rate of cognitive decline
    • Boyle PA, et al: Mild cognitive impairment: risk of Alzheimer disease and rate of cognitive decline. Neurology 2006; 67: 441-445.
    • (2006) Neurology , vol.67 , pp. 441-445
    • Boyle, P.A.1
  • 5
    • 0032988610 scopus 로고    scopus 로고
    • Mild cognitive impairment: Clinical characterization and outcome
    • Petersen RC, et al: Mild cognitive impairment: clinical characterization and outcome. Arch Neurol 1999; 56: 303-308.
    • (1999) Arch Neurol , vol.56 , pp. 303-308
    • Petersen, R.C.1
  • 6
    • 0037180462 scopus 로고    scopus 로고
    • Incidence and outcome of mild cognitive impairment in a population-based prospective cohort
    • Larrieu S, et al: Incidence and outcome of mild cognitive impairment in a population-based prospective cohort. Neurology 2002; 59: 1594-1599.
    • (2002) Neurology , vol.59 , pp. 1594-1599
    • Larrieu, S.1
  • 7
    • 33750987305 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of developing Alzheimer disease: Results from the Framingham Study
    • Akomolafe A, et al: Diabetes mellitus and risk of developing Alzheimer disease: results from the Framingham Study. Arch Neurol 2006; 63: 1551-1555.
    • (2006) Arch Neurol , vol.63 , pp. 1551-1555
    • Akomolafe, A.1
  • 8
    • 2442424380 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function
    • Arvanitakis Z, et al: Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function. Arch Neurol 2004; 61: 661-666.
    • (2004) Arch Neurol , vol.61 , pp. 661-666
    • Arvanitakis, Z.1
  • 9
    • 0030663143 scopus 로고    scopus 로고
    • The risk of dementia among persons with diabetes mellitus: A population-based cohort study
    • Leibson CL, et al: The risk of dementia among persons with diabetes mellitus: a population-based cohort study. Ann NY Acad Sci 1997; 826: 422-427.
    • (1997) Ann NY Acad Sci , vol.826 , pp. 422-427
    • Leibson, C.L.1
  • 10
    • 0031050268 scopus 로고    scopus 로고
    • Risk of dementia among persons with diabetes mellitus: A population-based cohort study
    • Leibson CL, et al: Risk of dementia among persons with diabetes mellitus: a population-based cohort study. Am J Epidemiol 1997; 145: 301-308.
    • (1997) Am J Epidemiol , vol.145 , pp. 301-308
    • Leibson, C.L.1
  • 11
    • 0035479310 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of Alzheimer's disease and dementia with stroke in a multiethnic cohort
    • Luchsinger JA, et al: Diabetes mellitus and risk of Alzheimer's disease and dementia with stroke in a multiethnic cohort. Am J Epidemiol 2001; 154: 635-641.
    • (2001) Am J Epidemiol , vol.154 , pp. 635-641
    • Luchsinger, J.A.1
  • 12
    • 0036973393 scopus 로고    scopus 로고
    • Diabetes mellitus and the risk of dementia, alzheimer's disease and vascular cognitive impairment in the canadian study of health and aging
    • MacKnight C, et al: Diabetes mellitus and the risk of dementia, Alzheimer's disease and vascular cognitive impairment in the Canadian Study of Health and Aging. Dement Geriatr Cogn Disord 2002; 14: 77-83.
    • (2002) Dement Geriatr Cogn Disord , vol.14 , pp. 77-83
    • Macknight, C.1
  • 13
    • 0032764016 scopus 로고    scopus 로고
    • Diabetes mellitus and the risk of dementia: The Rotterdam Study
    • Ott A, et al: Diabetes mellitus and the risk of dementia: The Rotterdam Study. Neurology 1999; 53: 1937-1942.
    • (1999) Neurology , vol.53 , pp. 1937-1942
    • Ott, A.1
  • 14
    • 0036227542 scopus 로고    scopus 로고
    • Type 2 diabetes, apoe gene, and the risk for dementia and related pathologies: The honolulu-asia aging study
    • Peila R, Rodriguez BL, Launer LJ: Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study. Diabetes 2002; 51: 1256-1262.
    • (2002) Diabetes , vol.51 , pp. 1256-1262
    • Peila, R.1    Rodriguez, B.L.2    Launer, L.J.3
  • 15
    • 5344237420 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of dementia in the Kungsholmen project: A 6-year follow-up study
    • Xu WL, et al: Diabetes mellitus and risk of dementia in the Kungsholmen project: a 6-year follow-up study. Neurology 2004; 63: 1181-1186.
    • (2004) Neurology , vol.63 , pp. 1181-1186
    • Xu, W.L.1
  • 16
    • 5344256250 scopus 로고    scopus 로고
    • Hyperinsulinemia and risk of Alzheimer disease
    • Luchsinger JA, et al: Hyperinsulinemia and risk of Alzheimer disease. Neurology 2004; 63: 1187-1192.
    • (2004) Neurology , vol.63 , pp. 1187-1192
    • Luchsinger, J.A.1
  • 17
    • 9844229370 scopus 로고    scopus 로고
    • Association between features of the insulin resistance syndrome and Alzheimer's disease independently of apolipoprotein E4 phenotype: Cross sectional population based study
    • Kuusisto J, et al: Association between features of the insulin resistance syndrome and Alzheimer's disease independently of apolipoprotein E4 phenotype: cross sectional population based study. BMJ 1997; 315: 1045-1049.
    • (1997) BMJ , vol.315 , pp. 1045-1049
    • Kuusisto, J.1
  • 18
    • 62449142597 scopus 로고    scopus 로고
    • The role of metabolic disorders in Alzheimer disease and vascular dementia: Two roads converged
    • Craft S: The role of metabolic disorders in Alzheimer disease and vascular dementia: two roads converged. Arch Neurol 2009; 66: 300-305.
    • (2009) Arch Neurol , vol.66 , pp. 300-305
    • Craft, S.1
  • 19
    • 15244351255 scopus 로고    scopus 로고
    • Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes?
    • Steen E, et al: Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes? J Alzheimers Dis 2005; 7: 63-80.
    • (2005) J Alzheimers Dis , vol.7 , pp. 63-80
    • Steen, E.1
  • 20
    • 0033678865 scopus 로고    scopus 로고
    • Insulin resistance with aging: Effects of diet and exercise
    • Ryan AS: Insulin resistance with aging: effects of diet and exercise. Sports Med 2000; 30: 327-346.
    • (2000) Sports Med , vol.30 , pp. 327-346
    • Ryan, A.S.1
  • 21
    • 19244365650 scopus 로고    scopus 로고
    • Thiazolidinediones
    • Yki-Jarvinen H: Thiazolidinediones. N Engl J Med 2004; 351: 1106-1118.
    • (2004) N Engl J Med , vol.351 , pp. 1106-1118
    • Yki-Jarvinen, H.1
  • 22
    • 5344237365 scopus 로고    scopus 로고
    • The effects of exercise training on elderly persons with cognitive impairment and dementia: A meta-analysis
    • Heyn P, Abreu BC, Ottenbacher KJ: The effects of exercise training on elderly persons with cognitive impairment and dementia: a meta-analysis. Arch Phys Med Rehabil 2004; 85: 1694-1704.
    • (2004) Arch Phys Med Rehabil , vol.85 , pp. 1694-1704
    • Heyn, P.1    Abreu, B.C.2    Ottenbacher, K.J.3
  • 23
    • 33644592598 scopus 로고    scopus 로고
    • Preserved cognition in patients with early Alzheimer disease and amnestic mild cognitive impairment during treatment with rosiglitazone: A preliminary study
    • Watson GS, et al: Preserved cognition in patients with early Alzheimer disease and amnestic mild cognitive impairment during treatment with rosiglitazone: a preliminary study. Am J Geriatr Psychiatry 2005; 13: 950-958.
    • (2005) Am J Geriatr Psychiatry , vol.13 , pp. 950-958
    • Watson, G.S.1
  • 24
    • 33745266146 scopus 로고    scopus 로고
    • Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease
    • Risner ME, et al: Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease. Pharmacogenomics J 2006; 6: 246-254.
    • (2006) Pharmacogenomics J , vol.6 , pp. 246-254
    • Risner, M.E.1
  • 25
    • 58149265311 scopus 로고    scopus 로고
    • Pioglitazone improved cognition in a pilot study on patients with Alzheimer's disease and mild cognitive impairment with diabetes mellitus
    • Hanyu H, et al: Pioglitazone improved cognition in a pilot study on patients with Alzheimer's disease and mild cognitive impairment with diabetes mellitus. J Am Geriatr Soc 2009; 57: 177-179.
    • (2009) J Am Geriatr Soc , vol.57 , pp. 177-179
    • Hanyu, H.1
  • 26
    • 79959479102 scopus 로고    scopus 로고
    • Efficacy of PPAR-gamma agonist pioglitazone in mild Alzheimer disease
    • Sato T, et al: Efficacy of PPAR-gamma agonist pioglitazone in mild Alzheimer disease. Neurobiol Aging 2011: 32: 1626-1633.
    • (2011) Neurobiol Aging , vol.32 , pp. 1626-1633
    • Sato, T.1
  • 27
    • 4544335597 scopus 로고    scopus 로고
    • Mild cognitive impairment as a diagnostic entity
    • Petersen RC: Mild cognitive impairment as a diagnostic entity. J Intern Med 2004; 256: 183-194.
    • (2004) J Intern Med , vol.256 , pp. 183-194
    • Petersen, R.C.1
  • 28
    • 0035897696 scopus 로고    scopus 로고
    • Executive summary of the third report of the national cholesterol education program (ncep) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults adult treatment panel iii
    • Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001; 285: 2486-2497.
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 29
    • 0016823810 scopus 로고
    • Mini-mental state'. A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR: 'Mini-mental state'. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12: 189-198.
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 30
    • 0027425211 scopus 로고
    • The clinical dementia rating (cdr): Current version and scoring rules
    • Morris JC: The Clinical Dementia Rating (CDR): current version and scoring rules. Neurology 1993; 43: 2412-2414.
    • (1993) Neurology , vol.43 , pp. 2412-2414
    • Morris, J.C.1
  • 31
    • 0030771116 scopus 로고    scopus 로고
    • An inventory to assess activities of daily living for clinical trials in alzheimer's disease the alzheimer's disease cooperative study
    • Galasko D, et al: An inventory to assess activities of daily living for clinical trials in Alzheimer's disease. The Alzheimer's Disease Cooperative Study. Alzheimer Dis Assoc Disord 1997; 11(suppl 2):S33-S39.
    • (1997) Alzheimer Dis Assoc Disord , vol.11 , pp. S33-S39
    • Galasko, D.1
  • 32
    • 84965520932 scopus 로고
    • The CES-D Scale: A self-report depression scale for research in the general population
    • Radloff LS: The CES-D Scale: a self-report depression scale for research in the general population. Appl Psychol Meas 1977; 1: 385-401.
    • (1977) Appl Psychol Meas , vol.1 , pp. 385-401
    • Radloff, L.S.1
  • 34
    • 0000054945 scopus 로고
    • L'examen psychologique dans les cas d'encéphalopathie traumatique
    • Rey RA: L'examen psychologique dans les cas d'encéphalopathie traumatique. Arch Psychol 1941; 28: 286-340.
    • (1941) Arch Psychol , vol.28 , pp. 286-340
    • Rey, R.A.1
  • 38
    • 0000119553 scopus 로고
    • Validity of the trail making test as an indicator of organic brain damage
    • Reitan RM: Validity of the Trail Making Test as an indicator of organic brain damage. Percept Mot Skills 1958; 8: 271-276.
    • (1958) Percept Mot Skills , vol.8 , pp. 271-276
    • Reitan, R.M.1
  • 42
    • 0030037822 scopus 로고    scopus 로고
    • Neuropsychological tests' norms above age 55: COWAT, BNT, MAE Token, WRAT-R Reading, AMNART, STROOP, TMT and JLO
    • Ivnik RJ, Malec JF, Smith GE, Tangalos EG, Petersen RC: Neuropsychological tests' norms above age 55: COWAT, BNT, MAE Token, WRAT-R Reading, AMNART, STROOP, TMT and JLO. Clin Neuropsychol 1996; 10: 262-278.
    • (1996) Clin Neuropsychol , vol.10 , pp. 262-278
    • Ivnik, R.J.1    Malec, J.F.2    Smith, G.E.3    Tangalos, E.G.4    Petersen, R.C.5
  • 45
    • 77957057877 scopus 로고    scopus 로고
    • Prevalence of mild cognitive impairment is higher in men the mayo clinic study of aging
    • Petersen RC, et al: Prevalence of mild cognitive impairment is higher in men. The Mayo Clinic Study of Aging. Neurology 2010; 75: 889-897.
    • (2010) Neurology , vol.75 , pp. 889-897
    • Petersen, R.C.1
  • 46
    • 84884139365 scopus 로고    scopus 로고
    • Mild cognitive impairment due to Alzheimer disease in the community
    • Petersen RC, et al: Mild cognitive impairment due to Alzheimer disease in the community. Ann Neurol 2013; 74: 199-208.
    • (2013) Ann Neurol , vol.74 , pp. 199-208
    • Petersen, R.C.1
  • 47
    • 0030814418 scopus 로고    scopus 로고
    • Development of cognitive instruments for use in clinical trials of antidementia drugs: Additions to the alzheimer's disease assessment scale that broaden its scope the alzheimer's disease cooperative study
    • Mohs RC, et al: Development of cognitive instruments for use in clinical trials of antidementia drugs: additions to the Alzheimer's Disease Assessment Scale that broaden its scope. The Alzheimer's Disease Cooperative Study. Alzheimer Dis Assoc Disord 1997; 11(suppl 2):S13-S21.
    • (1997) Alzheimer Dis Assoc Disord , vol.11 , pp. S13-S21
    • Mohs, R.C.1
  • 48
    • 33744513790 scopus 로고    scopus 로고
    • The Stroop color-word test: Influence of age, sex, and education; And normative data for a large sample across the adult age range
    • Van der Elst W, et al: The Stroop color-word test: influence of age, sex, and education; and normative data for a large sample across the adult age range. Assessment 2006; 13: 62-79.
    • (2006) Assessment , vol.13 , pp. 62-79
    • Van Der Elst, W.1
  • 50
    • 0031697956 scopus 로고    scopus 로고
    • Clock drawing test in very mild Alzheimer's disease
    • Esteban-Santillan C, et al: Clock drawing test in very mild Alzheimer's disease. J Am Geriatr Soc 1998; 46: 1266-1269.
    • (1998) J Am Geriatr Soc , vol.46 , pp. 1266-1269
    • Esteban-Santillan, C.1
  • 51
    • 0018520840 scopus 로고
    • Glucose clamp technique: A method for quantifying insulin secretion and resistance
    • DeFronzo RA, Tobin JD, Andres R: Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 1979; 237:E214-E223.
    • (1979) Am J Physiol , vol.237 , pp. E214-E223
    • Defronzo, R.A.1    Tobin, J.D.2    Andres, R.3
  • 52
    • 33846296315 scopus 로고    scopus 로고
    • Acute modulation of adipose tissue lipolysis by intravenous estrogens
    • Van Pelt RE, et al: Acute modulation of adipose tissue lipolysis by intravenous estrogens. Obesity (Silver Spring) 2006; 14: 2163-2172.
    • (2006) Obesity (Silver Spring) , vol.14 , pp. 2163-2172
    • Van Pelt, R.E.1
  • 53
    • 0026597462 scopus 로고
    • Arterial, arterialized venous, venous and capillary blood glucose measurements in normal man during hyperinsulinaemic euglycaemia and hypoglycaemia
    • Liu D, et al: Arterial, arterialized venous, venous and capillary blood glucose measurements in normal man during hyperinsulinaemic euglycaemia and hypoglycaemia. Diabetologia 1992; 35: 287-290.
    • (1992) Diabetologia , vol.35 , pp. 287-290
    • Liu, D.1
  • 54
    • 36949038203 scopus 로고    scopus 로고
    • The role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in Alzheimer's disease: Therapeutic implications
    • Jiang Q, Heneka M, Landreth GE: The role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in Alzheimer's disease: therapeutic implications. CNS Drugs 2008; 22: 1-14.
    • (2008) CNS Drugs , vol.22 , pp. 1-14
    • Jiang, Q.1    Heneka, M.2    Landreth, G.E.3
  • 55
    • 77956090575 scopus 로고    scopus 로고
    • Rosiglitazone monotherapy in mild-to-moderate Alzheimer's disease: Results from a randomized, double-blind, placebo-controlled phase III study
    • Gold M, et al: Rosiglitazone monotherapy in mild-to-moderate Alzheimer's disease: results from a randomized, double-blind, placebo-controlled phase III study. Dement Geriatr Cogn Disord 2010; 30: 131-146.
    • (2010) Dement Geriatr Cogn Disord , vol.30 , pp. 131-146
    • Gold, M.1
  • 56
    • 79959974461 scopus 로고    scopus 로고
    • Rosiglitazone does not improve cognition or global function when used as adjunctive therapy to AChE inhibitors in mild-to-moderate Alzheimer's disease: Two phase 3 studies
    • Harrington C, et al: Rosiglitazone does not improve cognition or global function when used as adjunctive therapy to AChE inhibitors in mild-to-moderate Alzheimer's disease: two phase 3 studies. Curr Alzheimer Res 2011; 8: 592-606.
    • (2011) Curr Alzheimer Res , vol.8 , pp. 592-606
    • Harrington, C.1
  • 57
    • 78651322583 scopus 로고    scopus 로고
    • A randomized pilot clinical trial of the safety of pioglitazone in treatment of patients with Alzheimer disease
    • Geldmacher DS, et al: A randomized pilot clinical trial of the safety of pioglitazone in treatment of patients with Alzheimer disease. Arch Neurol 2011; 68: 45-50.
    • (2011) Arch Neurol , vol.68 , pp. 45-50
    • Geldmacher, D.S.1
  • 58
    • 0022361971 scopus 로고
    • Assessment of insulin sensitivity in vivo
    • Bergman RN, Finegood DT, Ader M: Assessment of insulin sensitivity in vivo. Endocr Rev 1985; 6: 45-86.
    • (1985) Endocr Rev , vol.6 , pp. 45-86
    • Bergman, R.N.1    Finegood, D.T.2    Ader, M.3
  • 59
    • 68949089312 scopus 로고    scopus 로고
    • Alzheimer's disease is type 3 diabetes-evidence reviewed
    • de la Monte SM, Wands JR: Alzheimer's disease is type 3 diabetes-evidence reviewed. J Diabetes Sci Technol 2008; 2: 1101-1113.
    • (2008) J Diabetes Sci Technol , vol.2 , pp. 1101-1113
    • De La Monte, S.M.1    Wands, J.R.2
  • 60
    • 84856805565 scopus 로고    scopus 로고
    • Effect of intranasal insulin on cognitive function: A systematic review
    • Shemesh E, et al: Effect of intranasal insulin on cognitive function: a systematic review. J Clin Endocrinol Metab 2012; 97: 366-376.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 366-376
    • Shemesh, E.1
  • 61
    • 76749124470 scopus 로고    scopus 로고
    • Healthy brain aging: Role of exercise and physical activity
    • Rolland Y, Abellan van Kan G, Vellas B: Healthy brain aging: role of exercise and physical activity. Clin Geriatr Med 2010; 26: 75-87.
    • (2010) Clin Geriatr Med , vol.26 , pp. 75-87
    • Rolland, Y.1    Abellan Van Kan, G.2    Vellas, B.3
  • 62
    • 44949098333 scopus 로고    scopus 로고
    • Physical activity and enhanced fitness to improve cognitive function in older people without known cognitive impairment
    • Angevaren M, et al: Physical activity and enhanced fitness to improve cognitive function in older people without known cognitive impairment. Cochrane Database Syst Rev 200;CD005381.
    • Cochrane Database Syst Rev , vol.200 , pp. CD005381
    • Angevaren, M.1
  • 63
    • 50949110086 scopus 로고    scopus 로고
    • Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: A randomized trial
    • Lautenschlager NT, et al: Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial. JAMA 2008; 300: 1027-1037.
    • (2008) JAMA , vol.300 , pp. 1027-1037
    • Lautenschlager, N.T.1
  • 64
    • 78650827898 scopus 로고    scopus 로고
    • Aerobic exercise improves cognition for older adults with glucose intolerance, a risk factor for Alzheimer's disease
    • Baker LD, et al: Aerobic exercise improves cognition for older adults with glucose intolerance, a risk factor for Alzheimer's disease. J Alzheimers Dis 2010; 22: 569-579.
    • (2010) J Alzheimers Dis , vol.22 , pp. 569-579
    • Baker, L.D.1
  • 65
    • 0033051657 scopus 로고    scopus 로고
    • Exercise: Effects on physical functional performance in independent older adults
    • Cress ME, et al: Exercise: effects on physical functional performance in independent older adults. J Gerontol A Biol Sci Med Sci 1999; 54:M242-M248.
    • (1999) J Gerontol A Biol Sci Med Sci , vol.54 , pp. M242-M248
    • Cress, M.E.1
  • 66
    • 12244264186 scopus 로고    scopus 로고
    • Protection of bone mass by estrogens and raloxifene during exercise-induced weight Loss
    • Gozansky WS, et al: Protection of bone mass by estrogens and raloxifene during exercise-induced weight Loss. J Clin Endocrinol Metab 2005; 90: 52-59.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 52-59
    • Gozansky, W.S.1
  • 67
    • 77953486374 scopus 로고    scopus 로고
    • Timing of ibuprofen use and bone mineral density adaptations to exercise training
    • Kohrt WM, et al: Timing of ibuprofen use and bone mineral density adaptations to exercise training. J Bone Miner Res 2010; 25: 1415-1422.
    • (2010) J Bone Miner Res , vol.25 , pp. 1415-1422
    • Kohrt, W.M.1
  • 68
    • 84868535585 scopus 로고    scopus 로고
    • Exercise for people in early-or mid-stage Parkinson disease: A 16-month randomized controlled trial
    • Schenkman M, et al: Exercise for people in early-or mid-stage Parkinson disease: a 16-month randomized controlled trial. Phys Ther 2012; 92: 1395-1410.
    • (2012) Phys Ther , vol.92 , pp. 1395-1410
    • Schenkman, M.1
  • 69
    • 84877719155 scopus 로고    scopus 로고
    • Effects of testosterone and progressive resistance exercise in healthy, highly functioning older men with low-normal testosterone levels
    • Hildreth KL, et al: Effects of testosterone and progressive resistance exercise in healthy, highly functioning older men with low-normal testosterone levels. J Clin Endocrinol Metab 2013; 98: 1891-1900.
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. 1891-1900
    • Hildreth, K.L.1
  • 70
    • 84873365126 scopus 로고    scopus 로고
    • Cognitive function affects trainability for physical performance in exercise intervention among older adults with mild cognitive impairment
    • Uemura K, et al: Cognitive function affects trainability for physical performance in exercise intervention among older adults with mild cognitive impairment. Clin Interv Aging 2013; 8: 97-102.
    • (2013) Clin Interv Aging , vol.8 , pp. 97-102
    • Uemura, K.1
  • 71
    • 84896903210 scopus 로고    scopus 로고
    • Adiponectin and waist circumference as predictors of insulin-resistance in women
    • Bonneau GA, Pedrozo WR, Berg G: Adiponectin and waist circumference as predictors of insulin-resistance in women. Diabetes Metab Syndr 2014; 8: 3-7.
    • (2014) Diabetes Metab Syndr , vol.8 , pp. 3-7
    • Bonneau, G.A.1    Pedrozo, W.R.2    Berg, G.3
  • 72
    • 5644289328 scopus 로고    scopus 로고
    • Adipocytokines, fat distribution, and insulin resistance in elderly men and women
    • Zoico E, et al: Adipocytokines, fat distribution, and insulin resistance in elderly men and women. J Gerontol A Biol Sci Med Sci 2004; 59:M935-M939.
    • (2004) J Gerontol A Biol Sci Med Sci , vol.59 , pp. M935-M939
    • Zoico, E.1
  • 73
    • 84855185039 scopus 로고    scopus 로고
    • Standards of medical care in diabetes-2012
    • Standards of medical care in diabetes-2012. Diabetes Care 2012; 35(suppl 1):S11-S63.
    • (2012) Diabetes Care , vol.35 , pp. S11-S63


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.