Acute modulation of adipose tissue lipolysis by intravenous estrogens

Obesity

Volumn 14, Issue 12, 2006, Pages 2163-2172

  Van Pelt, Rachael E ^a   Gozansky, Wendolyn S ^a   Hickner, Robert C ^b   Schwartz, Robert S ^a   Kohrt, Wendy M ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b EAST CAROLINA UNIVERSITY   (United States)

Author keywords

Abdominal; Femoral; Interstitial glycerol; Postmenopausal women; Subcutaneous adipose tissue

Indexed keywords

EID: 33846296315     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2006.253     Document Type: Article

References (42)

1. Revilla R, Revilla M, Villa LF, Cortes J, Arribas I, Rico H. Changes in body composition in women treated with gonado-tropin-releasing hormone antagonists. Maturitas. 1998;31: 63-8.
2. Yamasaki H, Douchi T, Yamamoto S, Oki T, Kuwahata R, Nagata Y. Body fat distribution and body composition during GnRH agonist therapy. Obstet Gynecol. 2001;97:338-42.
3. Espeland MA, Stefanick ML, Kritz-Silverstein D, et al. Effect of postmenopausal hormone therapy on body weight and waist and hip girths. J Clin Endocrinol Metab. 1997;82: 1549-56.
4. Gambacciani M, Ciaponi M, Cappagli B, et al. Body weight, body fat distribution, and hormonal replacement therapy in early postmenopausal women. J Clin Endocrinol Metab. 1997;82:414-7.
5. Jensen LB, Vestergaard P, Hermann AP, et al. Hormone replacement therapy dissociates fat mass and bone mass, and tends to reduce weight gain in early postmenopausal women: a randomized controlled 5-year clinical trial of the Danish Osteoporosis Prevention Study. J Bone Miner Res. 2003;18: 333-42.
6. Kohrt WM, Ehsani AA, Birge SJ. HRT preserves increases in bone mineral density and reductions in body fat after a supervised exercise program. J Appl Physiol. 1998;84:1506-12.
7. 2. Metabolism. 1991;40:990-6.
8. Richelsen B. Increased alpha 2- but similar beta-adrenergic receptor activities in subcutaneous gluteal adipocytes from females compared with males. Eur J Clin Invest. 1986;16: 302-9.
9. Mauriège P, Galitzky J, Berlan M, Lafontan M. Heterogeneous distribution of beta and alpha-2 adrenoceptor binding sites in human fat cells from various fat deposits: functional consequences. Eur J Clin Invest. 1987;17:156-65.
10. Rebuffé-Scrive M, Lonnroth P, Marin P, Wesslau C, Björntorp P, Smith U. Regional adipose tissue metabolism in men and postmenopausal women. Int J Obes. 1987;11:347-55.
11. Bolinder J, Engfeldt P, Ostman J, Arner P. Site differences in insulin receptor binding and insulin action in subcutaneous fat of obese females. J Clin Endocrinol Metab. 1983;57:455-61.
12. Cucinelli F, Paparella P, Soranna L, et al. Differential effect of transdermal estrogen plus progestagen replacement therapy on insulin metabolism in postmenopausal women: relation to their insulinemic secretion. Eur J Endocrinol. 1999;140:215-23.
13. Kimmerle R, Heinemann L, Heise T, et al. Influence of continuous combined estradiol-norethisterone acetate preparations on insulin sensitivity in postmenopausal nondiabetic women. Menopause. 1999;6:36-42.
14. Van Pelt RE, Gozansky WS, Schwartz RS, Kohrt WM. Intravenous estrogens increase insulin clearance and action in postmenopausal women. Am J Physiol Endocrinol Metab. 2003;285:E311-7.
15. Bays H, Mandarino L, DeFronzo RA. Role of the adipocyte, free fatty acids, and ectopic fat in the pathogenesis of type 2 diabetes mellitus: peroxisomal proliferator-activator receptor agonists provide a rational therapeutic approach. J Clin Endocrinol Metab. 2004;89:463-78.
16. Mayes JS, Watson GH. Direct effects of sex steroid hormones on adipose tissues and obesity. Obes Rev. 2004;5:197-216.
17. Jensen MD, Martin ML, Cryer PE, Roust LR. Effects of estrogen on free fatty acid metabolism in humans. Am J Physiol. 1994;266:E914-20.
18. DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol. 1979;237:E214-23.
19. Liu D, Moberg E, Kollind M, Lins PE, Adamson U, MacDonald IA. Arterial, arterialized venous, venous and capillary blood glucose measurements in normal man during hyperinsulaemic euglycaemia and hypoglycaemia. Diabetologia. 1992;35:287-90.
20. 2H stable isotopic tracers. Anal Biochem. 1992;205:172-8.
21. Steele R. Influences of glucose loading and of injected insulin on hepatic glucose output. Ann NY Acad Sci. 1959; 82:420-30.
22. Simonsen L, Bulow J, Madsen J. Adipose tissue metabolism in humans determined by vein catheterization and microdialysis techniques. Am J Physiol. 1994;266:E357-65.
23. Hickner RC, Rosdahl H, Borg I, Ungerstedt U, Jorfeldt L, Henriksson J. The ethanol technique of monitoring local blood flow changes in rat skeletal muscle: implications for microdialysis. Acta Physiol Scand. 1992;146:87-97.
24. Hickner RC, Fisher JS, Kohrt WM. Regional differences in interstitial glycerol concentration in subcutaneous adipose tissue of women. Am J Physiol. 1997;273:E1033-8.
25. Friedewald W, Levy R, Fredrickson D. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without the use of the preparative ultracentrifuge. Clin Chem. 1972;18:499-502.
26. Gambacciani M, Ciaponi M, Cappagli B, De Simone L, Orlandi R, Genazzani AR. Prospective evaluation of body weight and body fat distribution in early postmenopausal women with and without hormonal replacement therapy. Maturitas. 2001;39:125-32.
27. Hassager C, Christiansen C. Estrogen/gestagen therapy changes soft tissue body composition in postmenopausal women. Metabolism. 1989;38:662-5.
28. Kristensen K, Pedersen SB, Vestergaard P, Mosekilde L. Hormone replacement therapy affects body composition and leptin differently in obese and non-obese postmenopausal women. J Endocrinol. 1999;163:55-62.
29. Douchi T, Kuwahata R, Yamasaki H et al. Inverse relationship between the changes in trunk lean and fat mass during gonadotropin-releasing hormone agonist therapy. Maturitas. 2002;42:31-5.
30. Rebuffé-Scrive M, Eldh J, Hafstrom L-O, Björntorp P. Metabolism of mammary, abdominal, and femoral adipocytes in women before and after menopause. Metabolism. 1986;35:792-7.
31. Ferrara CM, Lynch NA, Nicklas BJ, Ryan AS, Berman DM. Differences in adipose tissue metabolism between postmenopausal and perimenopausal women. J Clin Endocrinol Metab. 2002;87:4166-70.
32. Darimont C, Delansorne R, Paris J, Ailhaud G, Negrel R. Influence of estrogenic status on the lipolytic action of parametrial adipose tissue in vivo: an in situ microdialysis study. Endocrinology. 1997;138:1092-6.
33. Pedersen SB, Kristensen K, Hermann PA, Katzenellenbogen JA, Richelsen B. Estrogen controls lipolysis by up-regulating a2A-adrenergic receptors directly in human adipose tissue through the estrogen receptor α. Implications for the female fat distribution. J Clin Endocrinol Metab. 2004;89:1869-78.
34. Garcia Dos Santos E, Dieudonne MN, Pecquery R, Le M, V, Giudicelli Y, Lacasa D. Rapid nongenomic E2 effects on p42/p44 MAPK, activator protein-1, and cAMP response element binding protein in rat white adipocytes. Endocrinology. 2002;143:930-40.
35. Kelly MJ, Lewin ER. Rapid actions of plasma membrane estrogen receptors. Trends Endocrinol Metab. 2001;12:152-5.
36. Levin E. Cellular functions of the plasma membrane receptor. Trends Endocrinol Metab. 1999;10:373-7.
37. D'Eon TM, Souza SC, Aronovitz M, Obin MS, Fried SK, Greenberg AS. Estrogen regulation of adiposity and fuel partitioning. Evidence of genomic and non-genomic regulation of lipogenic and oxidative pathways. J Biol Chem. 2005; 280:35983-91.
38. Lindberg U-B, Crona N, Silfverstolpe G, Björntorp P, Rebuffé-Scrive M. Regional adipose tissue metabolism in postmenopausal women after treatment with exogenous sex steroids. Hormone Metab Res. 1990;22:345-51.
39. Boschmann M, Ringel J, Klaus S, Sharma A. Metabolic and hemodynamic response of adipose tissue to angiotensin II. Obes Res. 2001;9:486-91.
40. Boschmann M, Rosenbaum M, Leibel RL, Segal KR. Metabolic and hemodynamic responses to exercise in subcutaneous adipose tissue and skeletal muscle. Int J Sports Med. 2002;23:537-43.
41. Lindheim SR, Duffy DM, Kojima T, Vijod MA, Stanczyk FZ, Lobo RA. The route of administration influences the effect of estrogen on insulin sensitivity in postmenopausal women. Fertil Steril. 1994;62:1176-80.
42. Lindheim SR, Presser SC, Ditkoff EC, Vijod MA, Stanczyk FZ, Lobo RA. A possible bimodal effect of estrogen on insulin sensitivity in postmenopausal women and the attenuating effect of added progestin. Fertil Steril. 1993; 60:664-7.