Molecular stratification of metastatic melanoma using gene expression profiling - Prediction of survival outcome and benefit from molecular targeted therapy

Oncotarget

Volumn 6, Issue 14, 2015, Pages 12297-12309

  Cirenajwis, Helena ^a   Ekedahl, Henrik ^a   Lauss, Martin ^a   Harbst, Katja ^a   Carneiro, Ana ^a,b   Enoksson, Jens ^b   Rosengren, Frida ^a   Werner Hartman, Linda ^a   Törngren, Therese ^a   Kvist, Anders ^a   Fredlund, Erik ^c   Bendahl, Pär Ola ^a   Jirström, Karin ^b   Lundgren, Lotta ^a,b   Howlin, Jillian ^a   Borg, Åke ^a   Gruvberger Saal, Sofia K ^a   Saal, Lao H ^a   Nielsen, Kari ^d   Ringnér, Markus ^a   Tsao, Hensin ^e,f   Olsson, Håkan ^a,b   Ingvar, Christian ^a   Staaf, Johan ^a   Jönsson, Göran ^a   more..

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

^d Helsingborg General Hospital   (Sweden)

^e HARVARD MEDICAL SCHOOL   (United States)

^f MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

BRAF; BRAF inhibitor; Gene expression; Melanoma; Mutation

Indexed keywords

B RAF KINASE; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DABRAFENIB; K RAS PROTEIN; MELANOMA ANTIGEN 3; TRAMETINIB; VEMURAFENIB; ANTINEOPLASTIC AGENT; CANCER VACCINE; TRANSCRIPTOME;

ADULT; ADVANCED CANCER; ARTICLE; BRAF GENE; CANCER CONTROL; CANCER PROGNOSIS; CANCER SURVIVAL; CCND1 GENE; CDK4 GENE; CDKN2A GENE; COHORT ANALYSIS; DISTANT METASTASIS; DRUG RESPONSE; FEMALE; GENE; GENE EXPRESSION PROFILING; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; KIT GENE; KRAS GENE; MAJOR CLINICAL STUDY; MALE; METASTATIC MELANOMA; NF1 GENE; NRAS GENE; PHENOTYPE; RB1 GENE; RETROSPECTIVE STUDY; RISK ASSESSMENT; SKIN BIOPSY; SKIN PIGMENTATION; AGED; DNA MUTATIONAL ANALYSIS; GENETICS; KAPLAN MEIER METHOD; MELANOMA; MIDDLE AGED; MOLECULARLY TARGETED THERAPY; MORTALITY; PATHOLOGY; PROCEDURES; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; SKIN TUMOR;

AGED; ANTINEOPLASTIC AGENTS; CANCER VACCINES; COHORT STUDIES; DNA MUTATIONAL ANALYSIS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MELANOMA; MIDDLE AGED; MOLECULAR TARGETED THERAPY; PHENOTYPE; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; SKIN NEOPLASMS; TRANSCRIPTOME;

EID: 84931405791     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3655     Document Type: Article

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