Matrix metalloproteinase 8 degrades apolipoprotein A-I and reduces its cholesterol efflux capacity

FASEB Journal

Volumn 29, Issue 4, 2015, Pages 1435-1445

  Salminen, Aino ^a,b   Åström, Pirjo ^c   Metso, Jari ^d   Soliymani, Rabah ^a   Salo, Tuula ^c   Jauhiainen, Matti ^d   Pussinen, Pirkko J ^a   Sorsa, Timo ^a,b,e  

^a UNIVERSITY OF HELSINKI   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c UNIVERSITY OF OULU   (Finland)

^d NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^e KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Atherosclerosis; Cholesterol metabolism; High density lipoprotein; Proteolytic enzyme

Indexed keywords

APOLIPOPROTEIN A1; CHOLESTEROL; DOXYCYCLINE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; NEUTROPHIL COLLAGENASE; HIGH DENSITY LIPOPROTEIN; MMP8 PROTEIN, HUMAN; MMP8 PROTEIN, MOUSE; PEPTIDE FRAGMENT; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; BLOOD VESSEL WALL; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; LIPID BLOOD LEVEL; MACROPHAGE; MALE; MASS SPECTROMETRY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; TRIACYLGLYCEROL BLOOD LEVEL; WILD TYPE; ACTIVE TRANSPORT; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; BLOOD; C57BL MOUSE; CELL LINE; CHEMISTRY; DEFICIENCY; GENETICS; KNOCKOUT MOUSE; METABOLISM; MOLECULAR GENETICS;

MUS;

AMINO ACID SEQUENCE; ANIMALS; APOLIPOPROTEIN A-I; ATHEROSCLEROSIS; BINDING SITES; BIOLOGICAL TRANSPORT, ACTIVE; CELL LINE; CHOLESTEROL; FEMALE; HUMANS; LIPOPROTEINS, HDL; MACROPHAGES; MALE; MATRIX METALLOPROTEINASE 8; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEOLYSIS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TRIGLYCERIDES;

EID: 84931362972     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.14-262956     Document Type: Article

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