-
1
-
-
84867874739
-
IMGN853, an anti-folate receptor I antibody-maytansinoid conjugate for targeted cancer therapy
-
Ab O. Bartle L. Rui L. Coccia J. Johnson H. Whiteman K. et al. (2011) IMGN853, an anti-folate receptor I antibody-maytansinoid conjugate for targeted cancer therapy. Cancer Res 71: 4576.
-
(2011)
Cancer Res
, vol.71
, pp. 4576
-
-
Ab, O.1
Bartle, L.2
Rui, L.3
Coccia, J.4
Johnson, H.5
Whiteman, K.6
-
2
-
-
34648832104
-
Overexpression of folate binding protein is associated with shortened progression-free survival in uterine adenocarcinomas
-
Allard J. Risinger J. Morrison C. Young G. Rose G. Fowler J. et al. (2007) Overexpression of folate binding protein is associated with shortened progression-free survival in uterine adenocarcinomas. Gynecol Oncol 107: 52–57.
-
(2007)
Gynecol Oncol
, vol.107
, pp. 52-57
-
-
Allard, J.1
Risinger, J.2
Morrison, C.3
Young, G.4
Rose, G.5
Fowler, J.6
-
3
-
-
0029818146
-
Folate receptors
-
Antony A. (1996) Folate receptors. Annu Rev Nutr 16: 501–521.
-
(1996)
Annu Rev Nutr
, vol.16
, pp. 501-521
-
-
Antony, A.1
-
4
-
-
84877579319
-
Farletuzumab (a monoclonal antibody against folate receptor alpha) in relapsed platinum-sensitive ovarian cancer
-
Armstrong D. White A. Weil S. Phillips M. Coleman R. (2013) Farletuzumab (a monoclonal antibody against folate receptor alpha) in relapsed platinum-sensitive ovarian cancer. Gynecol Oncol. 129: 452–458.
-
(2013)
Gynecol Oncol
, vol.129
, pp. 452-458
-
-
Armstrong, D.1
White, A.2
Weil, S.3
Phillips, M.4
Coleman, R.5
-
5
-
-
84869797748
-
Fourth World Antibody-Drug Conjugate Summit Frankfurt
-
Germany MAbs
-
Beck A. Lambert J. Sun M. Lin K. (2012) Fourth World Antibody-Drug Conjugate Summit: February 29 – March 1, 2012, Frankfurt, Germany. MAbs 4: 637–647.
-
(2012)
, vol.4
, pp. 637-647
-
-
Beck, A.1
Lambert, J.2
Sun, M.3
Lin, K.4
-
6
-
-
21244490748
-
The realisation of targeted antitumour therapy
-
Bicknell R. (2005) The realisation of targeted antitumour therapy. Br J Cancer 92(Suppl. 1): S2–S5.
-
(2005)
Br J Cancer
, vol.92
, pp. S2-S5
-
-
Bicknell, R.1
-
7
-
-
84869407359
-
Resistance and escape from antiangiogenesis therapy: clinical implications and future strategies
-
Bottsford-Miller J. Coleman R. Sood A. (2012) Resistance and escape from antiangiogenesis therapy: clinical implications and future strategies. J Clin Oncol 30: 4026–4034.
-
(2012)
J Clin Oncol
, vol.30
, pp. 4026-4034
-
-
Bottsford-Miller, J.1
Coleman, R.2
Sood, A.3
-
8
-
-
50549085621
-
Rationale for folate receptor alpha targeted therapy in “high risk” endometrial carcinomas
-
Brown J. Neuper C. Clayton A. Mariani A. Konecny G. Thomas M. et al. (2008) Rationale for folate receptor alpha targeted therapy in “high risk” endometrial carcinomas. Int J Cancer 123: 1699–1703.
-
(2008)
Int J Cancer
, vol.123
, pp. 1699-1703
-
-
Brown, J.1
Neuper, C.2
Clayton, A.3
Mariani, A.4
Konecny, G.5
Thomas, M.6
-
9
-
-
84871950953
-
Significance of folate receptor alpha and thymidylate synthase protein expression in patients with non-small-cell lung cancer treated with pemetrexed
-
Christoph D. Asuncion B. Hassan B. Tran C. Maltzman J. O'Shannessy D. et al. (2013) Significance of folate receptor alpha and thymidylate synthase protein expression in patients with non-small-cell lung cancer treated with pemetrexed. J Thorac Oncol 8: 19–30.
-
(2013)
J Thorac Oncol
, vol.8
, pp. 19-30
-
-
Christoph, D.1
Asuncion, B.2
Hassan, B.3
Tran, C.4
Maltzman, J.5
O'Shannessy, D.6
-
11
-
-
84879073124
-
Folate receptor alpha (FRA) expression remains unchanged in epithelial ovarian and endometrial cancer after chemotherapy
-
Despierre E. Lambrechts S. Leunen K. Berteloot P. Neven P. Amant F. et al. (2013) Folate receptor alpha (FRA) expression remains unchanged in epithelial ovarian and endometrial cancer after chemotherapy. Gynecol Oncol 130: 192–199.
-
(2013)
Gynecol Oncol
, vol.130
, pp. 192-199
-
-
Despierre, E.1
Lambrechts, S.2
Leunen, K.3
Berteloot, P.4
Neven, P.5
Amant, F.6
-
12
-
-
55349136976
-
A history of cancer chemotherapy
-
de Vita V. Jr Chu E. (2008) A history of cancer chemotherapy. Cancer Res 68: 8643–8653.
-
(2008)
Cancer Res
, vol.68
, pp. 8643-8653
-
-
de Vita, V.1
Chu, E.2
-
13
-
-
79952746215
-
EC-145, a folate-targeted Vinca alkaloid conjugate for the potential treatment of folate receptor-expressing cancers
-
Dosio F. Milla P. Cattel L. (2010) EC-145, a folate-targeted Vinca alkaloid conjugate for the potential treatment of folate receptor-expressing cancers. Curr Opin Investig Drugs 11: 1424–1433.
-
(2010)
Curr Opin Investig Drugs
, vol.11
, pp. 1424-1433
-
-
Dosio, F.1
Milla, P.2
Cattel, L.3
-
14
-
-
84914163404
-
The co-development of a folate receptor targeted drug conjugate vintafolide (EC145) and a folate receptor targeted imaging agent 99mTc-etarfolatide (EC20) in the treatment of advanced adenocarcinoma NSCLC
-
Edelman M. Bonomi P. Harb W. Pal S. Boccia R. Kraut M. et al. (2012 a) The co-development of a folate receptor targeted drug conjugate vintafolide (EC145) and a folate receptor targeted imaging agent 99mTc-etarfolatide (EC20) in the treatment of advanced adenocarcinoma NSCLC. J Thorac Oncol 7(Suppl. 1): S63.
-
(2012)
J Thorac Oncol
, vol.7
, pp. S63
-
-
Edelman, M.1
Bonomi, P.2
Harb, W.3
Pal, S.4
Boccia, R.5
Kraut, M.6
-
15
-
-
84866625235
-
Multicenter trial of EC 145 in advanced, folate-receptor positive adenocarcinoma of the lung
-
Edelman M. Harb W. Pal S. Boccia R. Kraut M. Bonomi P. et al. (2012 b) Multicenter trial of EC 145 in advanced, folate-receptor positive adenocarcinoma of the lung. J Thorac Oncol 7: 1618–1621.
-
(2012)
J Thorac Oncol
, vol.7
, pp. 1618-1621
-
-
Edelman, M.1
Harb, W.2
Pal, S.3
Boccia, R.4
Kraut, M.5
Bonomi, P.6
-
16
-
-
1942503303
-
Distribution, functionality and gene regulation of folate receptor isoforms: implications in targeted therapy
-
Elnakat H. Ratnam M. (2004) Distribution, functionality and gene regulation of folate receptor isoforms: implications in targeted therapy. Adv Drug Deliv Rev 56: 1067–1084.
-
(2004)
Adv Drug Deliv Rev
, vol.56
, pp. 1067-1084
-
-
Elnakat, H.1
Ratnam, M.2
-
17
-
-
32944463897
-
Role of folate receptor genes in reproduction and related cancers
-
Elnakat H. Ratnam M. (2006) Role of folate receptor genes in reproduction and related cancers. Front Biosci 11: 506–519.
-
(2006)
Front Biosci
, vol.11
, pp. 506-519
-
-
Elnakat, H.1
Ratnam, M.2
-
18
-
-
84871180236
-
Population pharmacokinetics of farletuzumab, a humanized monoclonal antibody against folate receptor alpha, in epithelial ovarian cancer
-
Farrell C. Schweizer C. Wustner J. Weil S. Namiki M. Nakano T. et al. (2012) Population pharmacokinetics of farletuzumab, a humanized monoclonal antibody against folate receptor alpha, in epithelial ovarian cancer. Cancer Chemother Pharmacol 70: 727–734.
-
(2012)
Cancer Chemother Pharmacol
, vol.70
, pp. 727-734
-
-
Farrell, C.1
Schweizer, C.2
Wustner, J.3
Weil, S.4
Namiki, M.5
Nakano, T.6
-
19
-
-
84874612774
-
Anti-vascular endothelial growth factor therapy in the era of personalized medicine
-
Feliz L. Tsimberidou A. (2013) Anti-vascular endothelial growth factor therapy in the era of personalized medicine. Cancer Chemother Pharmacol 72: 1–12.
-
(2013)
Cancer Chemother Pharmacol
, vol.72
, pp. 1-12
-
-
Feliz, L.1
Tsimberidou, A.2
-
20
-
-
84877755368
-
Mechanisms of resistance to anti-angiogenesis therapies
-
Giuliano S. Pages G. (2013) Mechanisms of resistance to anti-angiogenesis therapies. Biochimie 95: 1110–1119.
-
(2013)
Biochimie
, vol.95
, pp. 1110-1119
-
-
Giuliano, S.1
Pages, G.2
-
21
-
-
84881136041
-
Degradation of BMS-753493, a novel epothilone folate conjugate anticancer agent
-
Gokhale M. Thakur A. Rinaldi F. (2012) Degradation of BMS-753493, a novel epothilone folate conjugate anticancer agent. Drug Dev Ind Pharm 39: 1315–1327.
-
(2012)
Drug Dev Ind Pharm
, vol.39
, pp. 1315-1327
-
-
Gokhale, M.1
Thakur, A.2
Rinaldi, F.3
-
22
-
-
84865992002
-
Antifolates in cancer therapy: structure, activity and mechanisms of drug resistance
-
Gonen N. Assaraf Y. (2012) Antifolates in cancer therapy: structure, activity and mechanisms of drug resistance. Drug Resist Updat 15: 183–210.
-
(2012)
Drug Resist Updat
, vol.15
, pp. 183-210
-
-
Gonen, N.1
Assaraf, Y.2
-
23
-
-
84931395636
-
TARGET: a randomized phase II trial comparing vintafolide versus vintafolide plus docetaxel, versus docetaxel alone in second-line treatment of folate-receptor-positive nonsmall cell lung cancer (NSCLC) patients
-
abstract LBA40_PR.
-
Hanna N. Juhasz E. Cainap C. Gladkov O. Ramlau R. Juan-Vidal O. et al. (2014) TARGET: a randomized phase II trial comparing vintafolide versus vintafolide plus docetaxel, versus docetaxel alone in second-line treatment of folate-receptor-positive nonsmall cell lung cancer (NSCLC) patients. Ann Oncol 25(Suppl. 5): v1–v41; abstract LBA40_PR.
-
(2014)
Ann Oncol
, vol.25
, pp. v1-v41
-
-
Hanna, N.1
Juhasz, E.2
Cainap, C.3
Gladkov, O.4
Ramlau, R.5
Juan-Vidal, O.6
-
25
-
-
52049094603
-
Molecular mechanisms of adaptation to folate deficiency
-
Ifergan I. Assaraf Y. (2008) Molecular mechanisms of adaptation to folate deficiency. Vitam Horm 79: 99–143.
-
(2008)
Vitam Horm
, vol.79
, pp. 99-143
-
-
Ifergan, I.1
Assaraf, Y.2
-
26
-
-
33747855481
-
Comparing antibody and small-molecule therapies for cancer
-
Imai K. Takaoka A. (2006) Comparing antibody and small-molecule therapies for cancer. Nat Rev Cancer 6: 714–727.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 714-727
-
-
Imai, K.1
Takaoka, A.2
-
27
-
-
84867500287
-
Role of farletuzumab in epithelial ovarian carcinoma
-
Jelovac D. Armstrong D. (2012) Role of farletuzumab in epithelial ovarian carcinoma. Curr Pharm Des 18: 3812–3815.
-
(2012)
Curr Pharm Des
, vol.18
, pp. 3812-3815
-
-
Jelovac, D.1
Armstrong, D.2
-
29
-
-
0344401038
-
Receptor-mediated folate accumulation is regulated by the cellular folate content
-
Kamen B. Capdevila A. (1986) Receptor-mediated folate accumulation is regulated by the cellular folate content. Proc Natl Acad Sci U S A 83: 5983–5987.
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 5983-5987
-
-
Kamen, B.1
Capdevila, A.2
-
30
-
-
84863483737
-
Farletuzumab, an anti-folate receptor alpha antibody, does not block binding of folate or anti-folates to receptor nor does it alter the potency of anti-folates in vitro
-
Kamen B. Smith A. (2012) Farletuzumab, an anti-folate receptor alpha antibody, does not block binding of folate or anti-folates to receptor nor does it alter the potency of anti-folates in vitro. Cancer Chemother Pharmacol 70: 113–120.
-
(2012)
Cancer Chemother Pharmacol
, vol.70
, pp. 113-120
-
-
Kamen, B.1
Smith, A.2
-
31
-
-
84903154260
-
A phase I., first-in-human study to evaluate the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of IMGN 853 in patients (Pts) with epithelial ovarian cancer (EOC) and other FOLR1-positive solid tumors
-
abstract 2573.
-
Kirkjian C. LoRusso P. Sankhala K. Birrer M. Kirby M. Ladd S. et al. (2013) A phase I, first-in-human study to evaluate the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of IMGN 853 in patients (Pts) with epithelial ovarian cancer (EOC) and other FOLR1-positive solid tumors. J Clin Oncol 31(Suppl.): abstract 2573.
-
(2013)
J Clin Oncol
, vol.31
-
-
Kirkjian, C.1
LoRusso, P.2
Sankhala, K.3
Birrer, M.4
Kirby, M.5
Ladd, S.6
-
32
-
-
78049476593
-
Farletuzumab, a humanized monoclonal antibody against folate receptor alpha, in epithelial ovarian cancer: a phase I study
-
Konner J. Bell-McGuinn K. Sabbatini P. Hensley M. Tew W. Pandit-Taskar N. et al. (2010) Farletuzumab, a humanized monoclonal antibody against folate receptor alpha, in epithelial ovarian cancer: a phase I study. Clin Cancer Res 16:5288–5295.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 5288-5295
-
-
Konner, J.1
Bell-McGuinn, K.2
Sabbatini, P.3
Hensley, M.4
Tew, W.5
Pandit-Taskar, N.6
-
34
-
-
84914179824
-
Predicting response to EC 145 therapy using the folate receptor-specific radiodiagnostic imaging agent, 99mTc-EC20
-
Leamon C. Reddy J. Bloomfield A. Dorton R. Nelson M. Klein P. et al. (2012) Predicting response to EC 145 therapy using the folate receptor-specific radiodiagnostic imaging agent, 99mTc-EC20. Cancer Res 72(Suppl. 1): 3622.
-
(2012)
Cancer Res
, vol.72
, pp. 3622
-
-
Leamon, C.1
Reddy, J.2
Bloomfield, A.3
Dorton, R.4
Nelson, M.5
Klein, P.6
-
35
-
-
34447131647
-
Comparative preclinical activity of the folate-targeted Vinca alkaloid conjugates EC 140 and EC145
-
Leamon C. Reddy J. Vlahov I. Westrick E. Parker N. Nicoson J. et al. (2007 b) Comparative preclinical activity of the folate-targeted Vinca alkaloid conjugates EC 140 and EC145. Int J Cancer 121: 1585–1592.
-
(2007)
Int J Cancer
, vol.121
, pp. 1585-1592
-
-
Leamon, C.1
Reddy, J.2
Vlahov, I.3
Westrick, E.4
Parker, N.5
Nicoson, J.6
-
36
-
-
71449112911
-
Clinical pharmacokinetics and exposure-toxicity relationship of a folate-Vinca alkaloid conjugate EC 145 in cancer patients
-
Li J. Sausville E. Klein P. Morgenstern D. Leamon C. Messmann R. et al. (2009) Clinical pharmacokinetics and exposure-toxicity relationship of a folate-Vinca alkaloid conjugate EC 145 in cancer patients. J Clin Pharmacol 49: 1467–1476.
-
(2009)
J Clin Pharmacol
, vol.49
, pp. 1467-1476
-
-
Li, J.1
Sausville, E.2
Klein, P.3
Morgenstern, D.4
Leamon, C.5
Messmann, R.6
-
37
-
-
84869444058
-
Phase I study of folate conjugate EC 145 (vintafolide) in patients with refractory solid tumors
-
LoRusso P. Edelman M. Bever S. Forman K. Pilat M. Quinn M. et al. (2012) Phase I study of folate conjugate EC 145 (vintafolide) in patients with refractory solid tumors. J Clin Oncol 30: 4011–4016.
-
(2012)
J Clin Oncol
, vol.30
, pp. 4011-4016
-
-
LoRusso, P.1
Edelman, M.2
Bever, S.3
Forman, K.4
Pilat, M.5
Quinn, M.6
-
38
-
-
84886315269
-
Cancer immunotherapy: present status, future perspective, and a new paradigm of peptide immunotherapeutics
-
Miller M. Foy K. Kaumaya P. (2013) Cancer immunotherapy: present status, future perspective, and a new paradigm of peptide immunotherapeutics. Discov Med 15: 166–176.
-
(2013)
Discov Med
, vol.15
, pp. 166-176
-
-
Miller, M.1
Foy, K.2
Kaumaya, P.3
-
39
-
-
84906269444
-
Relationship of pharmacokinetics (PK), toxicity, and initial evidence of clinical activity with IMGN853, a folate receptor alpha (FRa) targeting antibody drug conjugate in patients (Pts) with epithelial ovarian cancer (EOC) and other FRa-positive solid tumors
-
abstract 5571.
-
Moore K. Ponte J. LoRusso P. Birrer M. Bauer T. Borghaei H. et al. (2014) Relationship of pharmacokinetics (PK), toxicity, and initial evidence of clinical activity with IMGN853, a folate receptor alpha (FRa) targeting antibody drug conjugate in patients (Pts) with epithelial ovarian cancer (EOC) and other FRa-positive solid tumors. J Clin Oncol 32(Suppl.): abstract 5571.
-
(2014)
J Clin Oncol
, vol.32
-
-
Moore, K.1
Ponte, J.2
LoRusso, P.3
Birrer, M.4
Bauer, T.5
Borghaei, H.6
-
40
-
-
84897043920
-
Phase 2 study of treatment of advanced ovarian cancer with folate receptor targeted therapeutic (vintafolide) and companion SPECT based imaging agent (99mTc-etarfolatide)
-
Morris R. Naumann R. Shah N. Mauer A. Strauss H. Uszler M. et al. (2014) Phase 2 study of treatment of advanced ovarian cancer with folate receptor targeted therapeutic (vintafolide) and companion SPECT based imaging agent (99mTc-etarfolatide). Ann Oncol 25: 852–858.
-
(2014)
Ann Oncol
, vol.25
, pp. 852-858
-
-
Morris, R.1
Naumann, R.2
Shah, N.3
Mauer, A.4
Strauss, H.5
Uszler, M.6
-
41
-
-
84891854386
-
Precedent: a randomized phase II trial comparing EC 145 (vintafolide) and pegylated liposomal doxorubicin (PLD) in combination, versus PLD alone, in patients with platinum-resistant ovarian cancer
-
Naumann R. Coleman R. Burger R. Sausville E. Kutarska E. Ghamande S. et al. (2013) Precedent: a randomized phase II trial comparing EC 145 (vintafolide) and pegylated liposomal doxorubicin (PLD) in combination, versus PLD alone, in patients with platinum-resistant ovarian cancer. J Clin Oncol 31: 4400–4406.
-
(2013)
J Clin Oncol
, vol.31
, pp. 4400-4406
-
-
Naumann, R.1
Coleman, R.2
Burger, R.3
Sausville, E.4
Kutarska, E.5
Ghamande, S.6
-
42
-
-
84861325993
-
High expression of folate receptor alpha in lung cancer correlates with adenocarcinoma histology and EGFR [corrected] mutation
-
Nunez M. Behrens C. Woods D. Lin H. Suraokar M. Kadara H. et al. (2012) High expression of folate receptor alpha in lung cancer correlates with adenocarcinoma histology and EGFR [corrected] mutation. J Thorac Oncol 7: 833–840.
-
(2012)
J Thorac Oncol
, vol.7
, pp. 833-840
-
-
Nunez, M.1
Behrens, C.2
Woods, D.3
Lin, H.4
Suraokar, M.5
Kadara, H.6
-
43
-
-
14644392093
-
Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay
-
Parker N. Turk M. Westrick E. Lewis J. Low P. Leamon C. (2005) Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay. Anal Biochem 338: 284–293.
-
(2005)
Anal Biochem
, vol.338
, pp. 284-293
-
-
Parker, N.1
Turk, M.2
Westrick, E.3
Lewis, J.4
Low, P.5
Leamon, C.6
-
44
-
-
9444279605
-
Ligand binding and kinetics of folate receptor recycling in vivo: impact on receptor-mediated drug delivery
-
Paulos C. Reddy J. Leamon C. Turk M. Low P. (2004) Ligand binding and kinetics of folate receptor recycling in vivo: impact on receptor-mediated drug delivery. Mol Pharmacol 66:1406–1414.
-
(2004)
Mol Pharmacol
, vol.66
, pp. 1406-1414
-
-
Paulos, C.1
Reddy, J.2
Leamon, C.3
Turk, M.4
Low, P.5
-
45
-
-
84859727702
-
EC145: a novel targeted agent for adenocarcinoma of the lung
-
Pribble P. Edelman M. (2012) EC145: a novel targeted agent for adenocarcinoma of the lung. Expert Opin Invest Drugs 21: 755–761.
-
(2012)
Expert Opin Invest Drugs
, vol.21
, pp. 755-761
-
-
Pribble, P.1
Edelman, M.2
-
46
-
-
0024440701
-
Homologous membrane folate binding proteins in human placenta: cloning and sequence of a cDNA
-
Ratnam M. Marquardt H. Duhring J. Freisheim J. (1989) Homologous membrane folate binding proteins in human placenta: cloning and sequence of a cDNA. Biochemistry 28: 8249–8254.
-
(1989)
Biochemistry
, vol.28
, pp. 8249-8254
-
-
Ratnam, M.1
Marquardt, H.2
Duhring, J.3
Freisheim, J.4
-
47
-
-
84898963005
-
Rational combination therapy of vintafolide (EC145) with commonly used chemotherapeutic drugs
-
Reddy J. Dorton R. Bloomfield A. Nelson M. Vetzel M. Guan J. et al. (2014) Rational combination therapy of vintafolide (EC145) with commonly used chemotherapeutic drugs. Clin Cancer Res 20: 2104–2114.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 2104-2114
-
-
Reddy, J.1
Dorton, R.2
Bloomfield, A.3
Nelson, M.4
Vetzel, M.5
Guan, J.6
-
48
-
-
34249321972
-
Preclinical evaluation of EC145, a folate-vinca alkaloid conjugate
-
Reddy J. Dorton R. Westrick E. Dawson A. Smith T. Xu L. et al. (2007) Preclinical evaluation of EC145, a folate-vinca alkaloid conjugate. Cancer Res 67: 4434–4442.
-
(2007)
Cancer Res
, vol.67
, pp. 4434-4442
-
-
Reddy, J.1
Dorton, R.2
Westrick, E.3
Dawson, A.4
Smith, T.5
Xu, L.6
-
49
-
-
0028301752
-
Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Physiologic and clinical implications
-
Ross J. Chaudhuri P. Ratnam M. (1994) Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Physiologic and clinical implications. Cancer 73: 2432–2443.
-
(1994)
Cancer
, vol.73
, pp. 2432-2443
-
-
Ross, J.1
Chaudhuri, P.2
Ratnam, M.3
-
50
-
-
33947362046
-
The folate receptor: what does it promise in tissue-targeted therapeutics?
-
Salazar M. Ratnam M. (2007) The folate receptor: what does it promise in tissue-targeted therapeutics? Cancer Metastasis Rev 26: 141–152.
-
(2007)
Cancer Metastasis Rev
, vol.26
, pp. 141-152
-
-
Salazar, M.1
Ratnam, M.2
-
51
-
-
0028206803
-
Identification of a novel folate receptor, a truncated receptor, and receptor type beta in hematopoietic cells: cDNA cloning, expression, immunoreactivity, and tissue specificity
-
Shen F. Ross J. Wang X. Ratnam M. (1994) Identification of a novel folate receptor, a truncated receptor, and receptor type beta in hematopoietic cells: cDNA cloning, expression, immunoreactivity, and tissue specificity. Biochemistry 33: 1209–1215.
-
(1994)
Biochemistry
, vol.33
, pp. 1209-1215
-
-
Shen, F.1
Ross, J.2
Wang, X.3
Ratnam, M.4
-
52
-
-
40649096363
-
Immunohistochemical expression of folate receptor alpha in colorectal carcinoma: patterns and biological significance
-
Shia J. Klimstra D. Nitzkorski J. Low P. Gonen M. Landmann R. et al. (2008) Immunohistochemical expression of folate receptor alpha in colorectal carcinoma: patterns and biological significance. Hum Pathol 39: 498–505.
-
(2008)
Hum Pathol
, vol.39
, pp. 498-505
-
-
Shia, J.1
Klimstra, D.2
Nitzkorski, J.3
Low, P.4
Gonen, M.5
Landmann, R.6
-
53
-
-
0034722715
-
Identification of two putative novel folate receptor genes in humans and mouse
-
Spiegelstein O. Eudy J. Finnell R. (2000) Identification of two putative novel folate receptor genes in humans and mouse. Gene 258: 117–125.
-
(2000)
Gene
, vol.258
, pp. 117-125
-
-
Spiegelstein, O.1
Eudy, J.2
Finnell, R.3
-
54
-
-
77951494873
-
Targeted cancer therapies in the twenty-first century: lessons from imatinib
-
Stegmeier F. Warmuth M. Sellers W. Dorsch M. (2010) Targeted cancer therapies in the twenty-first century: lessons from imatinib. Clin Pharmacol Ther 87: 543–552.
-
(2010)
Clin Pharmacol Ther
, vol.87
, pp. 543-552
-
-
Stegmeier, F.1
Warmuth, M.2
Sellers, W.3
Dorsch, M.4
-
55
-
-
84881095514
-
Erlotinib resistance in lung cancer: current progress and future perspectives
-
Tang J. Salama R. Gadgeel S. Sarkar F. Ahmad A. (2013) Erlotinib resistance in lung cancer: current progress and future perspectives. Front Pharmacol 4: 15.
-
(2013)
Front Pharmacol
, vol.4
, pp. 15
-
-
Tang, J.1
Salama, R.2
Gadgeel, S.3
Sarkar, F.4
Ahmad, A.5
-
56
-
-
84865243485
-
Overcoming resistance to antiangiogenic therapies
-
Tejpar S. Prenen H. Mazzone M. (2012) Overcoming resistance to antiangiogenic therapies. Oncologist 17: 1039–1050.
-
(2012)
Oncologist
, vol.17
, pp. 1039-1050
-
-
Tejpar, S.1
Prenen, H.2
Mazzone, M.3
-
57
-
-
84864274164
-
Clinical translation of folate receptor-targeted therapeutics
-
Teng L. Xie J. Teng L. Lee R. (2012) Clinical translation of folate receptor-targeted therapeutics. Expert Opin Drug Deliv 9:901–908.
-
(2012)
Expert Opin Drug Deliv
, vol.9
, pp. 901-908
-
-
Teng, L.1
Teng, L.2
Xie, J.3
Lee, R.4
-
59
-
-
84862209448
-
A novel splice variant of folate receptor 4 predominantly expressed in regulatory T cells
-
Tian Y. Wu G. Xing J. Tang J. Zhang Y. Huang Z. et al. (2012) A novel splice variant of folate receptor 4 predominantly expressed in regulatory T cells. BMC Immunol 13: 30.
-
(2012)
BMC Immunol
, vol.13
, pp. 30
-
-
Tian, Y.1
Wu, G.2
Xing, J.3
Tang, J.4
Zhang, Y.5
Huang, Z.6
-
61
-
-
0031944910
-
Expression of folate binding protein as a prognostic factor for response to platinum-containing chemotherapy and survival in human ovarian cancer
-
Toffoli G. Russo A. Gallo A. Cernigoi C. Miotti S. Sorio R. et al. (1998) Expression of folate binding protein as a prognostic factor for response to platinum-containing chemotherapy and survival in human ovarian cancer. Int J Cancer 79: 121–126.
-
(1998)
Int J Cancer
, vol.79
, pp. 121-126
-
-
Toffoli, G.1
Russo, A.2
Gallo, A.3
Cernigoi, C.4
Miotti, S.5
Sorio, R.6
-
62
-
-
84904278154
-
Double-blind, placebo-controlled study of weekly fartetuzumab with carboplatin / taxane in subjects with platinum-sensitive ovarian cancer in first relapse
-
Vergote I. Armstrong D. Scambia G. Fujiwara K. Gorbunova V. Schweizer C. et al. (2013) Double-blind, placebo-controlled study of weekly fartetuzumab with carboplatin / taxane in subjects with platinum-sensitive ovarian cancer in first relapse. Int J Gynecol Cancer 23(Suppl. 1): 11.
-
(2013)
Int J Gynecol Cancer
, vol.23
, pp. 11
-
-
Vergote, I.1
Armstrong, D.2
Scambia, G.3
Fujiwara, K.4
Gorbunova, V.5
Schweizer, C.6
-
63
-
-
84863946983
-
Engineering folate-drug conjugates to target cancer: from chemistry to clinic
-
Vlahov I. Leamon C. (2012) Engineering folate-drug conjugates to target cancer: from chemistry to clinic. Bioconjug Chem 23: 1357–1369.
-
(2012)
Bioconjug Chem
, vol.23
, pp. 1357-1369
-
-
Vlahov, I.1
Leamon, C.2
-
64
-
-
33747349484
-
Design and regioselective synthesis of a new generation of targeted chemotherapeutics. Part 1: EC145, a folic acid conjugate of desacetylvinblastine monohydrazide
-
Vlahov I. Santhapuram H. Kleindl P. Howard S. Stanford K. Leamon C. (2006) Design and regioselective synthesis of a new generation of targeted chemotherapeutics. Part 1: EC145, a folic acid conjugate of desacetylvinblastine monohydrazide. Bioorg Med Chem Lett 16: 5093–5096.
-
(2006)
Bioorg Med Chem Lett
, vol.16
, pp. 5093-5096
-
-
Vlahov, I.1
Santhapuram, H.2
Kleindl, P.3
Howard, S.4
Stanford, K.5
Leamon, C.6
-
65
-
-
0026752798
-
Distribution of the folate receptor GP 38 in normal and malignant cell lines and tissues
-
Weitman S. Lark R. Coney L. Fort D. Frasca V. Zurawski V. Jr et al. (1992 a) Distribution of the folate receptor GP 38 in normal and malignant cell lines and tissues. Cancer Res 52: 3396–3401.
-
(1992)
Cancer Res
, vol.52
, pp. 3396-3401
-
-
Weitman, S.1
Lark, R.2
Coney, L.3
Fort, D.4
Frasca, V.5
Zurawski, V.6
-
66
-
-
0026476410
-
Cellular localization of the folate receptor: potential role in drug toxicity and folate homeostasis
-
Weitman S. Weinberg A. Coney L. Zurawski V. Jennings D. Kamen B. (1992 b) Cellular localization of the folate receptor: potential role in drug toxicity and folate homeostasis. Cancer Res 52: 6708–6711.
-
(1992)
Cancer Res
, vol.52
, pp. 6708-6711
-
-
Weitman, S.1
Weinberg, A.2
Coney, L.3
Zurawski, V.4
Jennings, D.5
Kamen, B.6
-
67
-
-
0029118446
-
Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity
-
Westerhof G. Schornagel J. Kathmann I. Jackman A. Rosowsky A. Forsch R. et al. (1995) Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity. Mol Pharmacol 48: 459–471.
-
(1995)
Mol Pharmacol
, vol.48
, pp. 459-471
-
-
Westerhof, G.1
Schornagel, J.2
Kathmann, I.3
Jackman, A.4
Rosowsky, A.5
Forsch, R.6
-
68
-
-
63249102414
-
A role for the proton-coupled folate transporter (PCFT-SLC46A1) in folate receptor-mediated endocytosis
-
Zhao R. Min S. Wang Y. Campanella E. Low P. Goldman I. (2009) A role for the proton-coupled folate transporter (PCFT-SLC46A1) in folate receptor-mediated endocytosis. J Biol Chem 284: 4267–4274.
-
(2009)
J Biol Chem
, vol.284
, pp. 4267-4274
-
-
Zhao, R.1
Min, S.2
Wang, Y.3
Campanella, E.4
Low, P.5
Goldman, I.6
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