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Volumn 125, Issue 24, 2015, Pages 3756-3759

Evidence of an epigenetic origin for high-risk 1q21 copy number aberrations in multiple myeloma

Author keywords

[No Author keywords available]

Indexed keywords

AZACITIDINE; DNA; MYC PROTEIN;

EID: 84931292225     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2015-03-632075     Document Type: Article
Times cited : (40)

References (25)
  • 1
    • 84860219443 scopus 로고    scopus 로고
    • The genetic architecture of multiple myeloma
    • Morgan GJ, Walker BA, Davies FE. The genetic architecture of multiple myeloma. Nat Rev Cancer. 2012;12(5):335-348.
    • (2012) Nat Rev Cancer. , vol.12 , Issue.5 , pp. 335-348
    • Morgan, G.J.1    Walker, B.A.2    Davies, F.E.3
  • 2
    • 84893782640 scopus 로고    scopus 로고
    • IMWG consensus on risk stratification in multiple myeloma
    • Chng WJ, Dispenzieri A, Chim CS, et al International Myeloma Working Group. IMWG consensus on risk stratification in multiple myeloma. Leukemia. 2014;28(2):269-277.
    • (2014) Leukemia , vol.28 , Issue.2 , pp. 269-277
    • Chng, W.J.1    Dispenzieri, A.2    Chim, C.S.3
  • 3
    • 33947217497 scopus 로고    scopus 로고
    • A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1
    • Shaughnessy JD Jr, Zhan F, Burington BE, et al. A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1. Blood. 2007;109(6):2276-2284.
    • (2007) Blood , vol.109 , Issue.6 , pp. 2276-2284
    • Shaughnessy, J.D.1    Zhan, F.2    Burington, B.E.3
  • 4
    • 84863919796 scopus 로고    scopus 로고
    • Long-term analysis of the IFM 99 trials for myeloma: cytogenetic abnormalities [t(4;14), del(17p), 1q gains] play a major role in defining long-term survival
    • Avet-Loiseau H, Attal M, Campion L, et al. Long-term analysis of the IFM 99 trials for myeloma: cytogenetic abnormalities [t(4;14), del(17p), 1q gains] play a major role in defining long-term survival. JClinOncol.2012;30(16): 1949-1952.
    • (2012) JClinOncol , vol.30 , Issue.16 , pp. 1949-1952
    • Avet-Loiseau, H.1    Attal, M.2    Campion, L.3
  • 5
    • 84856706335 scopus 로고    scopus 로고
    • A novel prognostic model in myeloma based on cosegregating adverse FISH lesions and the ISS: Analysis of patients treated in the MRC Myeloma IX trial
    • Boyd KD, Ross FM, Chiecchio L, et al NCRI Haematology Oncology Studies Group. A novel prognostic model in myeloma based on cosegregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial. Leukemia. 2012;26(2):349-355.
    • (2012) Leukemia. , vol.26 , Issue.2 , pp. 349-355
    • Boyd, K.D.1    Ross, F.M.2    Chiecchio, L.3
  • 6
    • 33748196399 scopus 로고    scopus 로고
    • Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: Incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation
    • Hanamura I, Stewart JP, Huang Y, et al. Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation. Blood. 2006;108(5):1724-1732.
    • (2006) Blood. , vol.108 , Issue.5 , pp. 1724-1732
    • Hanamura, I.1    Stewart, J.P.2    Huang, Y.3
  • 7
    • 33748190743 scopus 로고    scopus 로고
    • Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma
    • Walker BA, Leone PE, Jenner MW, et al. Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma. Blood. 2006; 108(5):1733-1743.
    • (2006) Blood. , vol.108 , Issue.5 , pp. 1733-1743
    • Walker, B.A.1    Leone, P.E.2    Jenner, M.W.3
  • 8
    • 0032030675 scopus 로고    scopus 로고
    • Jumping translocations of chromosome 1q in multiple myeloma: Evidence for a mechanism involving decondensation of pericentromeric heterochromatin
    • Sawyer JR, Tricot G, Mattox S, Jagannath S, Barlogie B. Jumping translocations of chromosome 1q in multiple myeloma: evidence for a mechanism involving decondensation of pericentromeric heterochromatin. Blood. 1998; 91(5):1732-1741.
    • (1998) Blood. , vol.91 , Issue.5 , pp. 1732-1741
    • Sawyer, J.R.1    Tricot, G.2    Mattox, S.3    Jagannath, S.4    Barlogie, B.5
  • 9
    • 9644289448 scopus 로고    scopus 로고
    • Genomic instability in multiple myeloma: Evidence for jumping segmental duplications of chromosome arm 1q
    • Sawyer JR, Tricot G, Lukacs JL, et al. Genomic instability in multiple myeloma: evidence for jumping segmental duplications of chromosome arm 1q. Genes Chromosomes Cancer. 2005; 42(1):95-106.
    • (2005) Genes Chromosomes Cancer. , vol.42 , Issue.1 , pp. 95-106
    • Sawyer, J.R.1    Tricot, G.2    Lukacs, J.L.3
  • 11
    • 77956288766 scopus 로고    scopus 로고
    • DNA methylation analysis determines the high frequency of genic hypomethylation and low frequency of hypermethylation events in plasma cell tumors
    • Salhia B, Baker A, Ahmann G, Auclair D, Fonseca R, Carpten J. DNA methylation analysis determines the high frequency of genic hypomethylation and low frequency of hypermethylation events in plasma cell tumors. Cancer Res. 2010;70(17):6934-6944.
    • (2010) Cancer Res. , vol.70 , Issue.17 , pp. 6934-6944
    • Salhia, B.1    Baker, A.2    Ahmann, G.3    Auclair, D.4    Fonseca, R.5    Carpten, J.6
  • 12
    • 78751508049 scopus 로고    scopus 로고
    • Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma
    • Walker BA, Wardell CP, Chiecchio L, et al. Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma. Blood. 2011;117(2):553-562.
    • (2011) Blood. , vol.117 , Issue.2 , pp. 553-562
    • Walker, B.A.1    Wardell, C.P.2    Chiecchio, L.3
  • 13
    • 84874856954 scopus 로고    scopus 로고
    • Myeloma is characterized by stage-specific alterations in DNA methylation that occur early during myelomagenesis
    • Heuck CJ, Mehta J, Bhagat T, et al. Myeloma is characterized by stage-specific alterations in DNA methylation that occur early during myelomagenesis. J Immunol. 2013;190(6): 2966-2975.
    • (2013) J Immunol. , vol.190 , Issue.6 , pp. 2966-2975
    • Heuck, C.J.1    Mehta, J.2    Bhagat, T.3
  • 14
    • 69449085661 scopus 로고    scopus 로고
    • Differential repetitive DNA methylation in multiple myeloma molecular subgroups
    • Bollati V, Fabris S, Pegoragro V, et al. Differential repetitive DNA methylation in multiple myeloma molecular subgroups. Carcinogenesis. 2009; 30(8):1330-1335.
    • (2009) Carcinogenesis , vol.30 , Issue.8 , pp. 1330-1335
    • Bollati, V.1    Fabris, S.2    Pegoragro, V.3
  • 15
    • 84871369855 scopus 로고    scopus 로고
    • Genomic vulnerability to LINE-1 hypomethylation is a potential determinant of the clinicogenetic features of multiple myeloma
    • Aoki Y, Nojima M, Suzuki H, et al. Genomic vulnerability to LINE-1 hypomethylation is a potential determinant of the clinicogenetic features of multiple myeloma. Genome Med. 2012;4(12):101.
    • (2012) Genome Med , vol.4 , Issue.12 , pp. 101
    • Aoki, Y.1    Nojima, M.2    Suzuki, H.3
  • 16
    • 0017079865 scopus 로고
    • Segmentation of human chromosomes induced by 5-ACR (5-azacytidine)
    • Viegas-Péquignot E, Dutrillaux B. Segmentation of human chromosomes induced by 5-ACR (5-azacytidine). Hum Genet. 1976;34(3):247-254.
    • (1976) Hum Genet. , vol.34 , Issue.3 , pp. 247-254
    • Viegas-Péquignot, E.1    Dutrillaux, B.2
  • 17
    • 0021683604 scopus 로고
    • 5-Azacytidine-induced undercondensations in human chromosomes
    • Schmid M, Haaf T, Grunert D. 5-Azacytidine-induced undercondensations in human chromosomes. Hum Genet. 1984;67(3):257-263.
    • (1984) Hum Genet. , vol.67 , Issue.3 , pp. 257-263
    • Schmid, M.1    Haaf, T.2    Grunert, D.3
  • 18
    • 0027522464 scopus 로고
    • Specific induction of uncoiling and recombination by azacytidine in classical satellite-containing constitutive heterochromatin
    • Kokalj-Vokac N, Almeida A, Viegas-Péquignot E, Jeanpierre M, Malfoy B, Dutrillaux B. Specific induction of uncoiling and recombination by azacytidine in classical satellite-containing constitutive heterochromatin. Cytogenet Cell Genet. 1993;63(1):11-15.
    • (1993) Cytogenet Cell Genet. , vol.63 , Issue.1 , pp. 11-15
    • Kokalj-Vokac, N.1    Almeida, A.2    Viegas-Péquignot, E.3    Jeanpierre, M.4    Malfoy, B.5    Dutrillaux, B.6
  • 19
    • 0028947749 scopus 로고
    • The effects of 5-azacytidine and 5-azadeoxycytidine on chromosome structure and function: Implications for methylation-associated cellular processes
    • Haaf T. The effects of 5-azacytidine and 5-azadeoxycytidine on chromosome structure and function: implications for methylation-associated cellular processes. Pharmacol Ther. 1995;65(1): 19-46.
    • (1995) Pharmacol Ther. , vol.65 , Issue.1 , pp. 19-46
    • Haaf, T.1
  • 20
    • 83555173292 scopus 로고    scopus 로고
    • Satellite 2 demethylation induced by 5-azacytidine is associated with missegregation of chromosomes 1 and 16 in human somatic cells
    • Prada D, Gonzalez R, Sanchez L, et al. Satellite 2 demethylation induced by 5-azacytidine is associated with missegregation of chromosomes 1 and 16 in human somatic cells. Mutation Res. 2012;729(1-2):100-105.
    • (2012) Mutation Res. , vol.729 , Issue.1-2 , pp. 100-105
    • Prada, D.1    Gonzalez, R.2    Sanchez, L.3
  • 21
    • 0018168775 scopus 로고
    • The characterization of high-resolution G-banded chromosomes of man
    • Yunis JJ, Sawyer JR, Ball DW. The characterization of high-resolution G-banded chromosomes of man. Chromosoma. 1978;67(4): 293-307.
    • (1978) Chromosoma. , vol.67 , Issue.4 , pp. 293-307
    • Yunis, J.J.1    Sawyer, J.R.2    Ball, D.W.3
  • 22
    • 70350461710 scopus 로고    scopus 로고
    • Evidence for a novel mechanism for gene amplification in multiple myeloma: 1q12 pericentromeric heterochromatin mediates breakage-fusion-bridge cycles of a 1q12 approximately 23 amplicon
    • Sawyer JR, Tian E, Thomas E, et al. Evidence for a novel mechanism for gene amplification in multiple myeloma: 1q12 pericentromeric heterochromatin mediates breakage-fusion-bridge cycles of a 1q12 approximately 23 amplicon. Br J Haematol. 2009;147(4):484-494.
    • (2009) Br J Haematol. , vol.147 , Issue.4 , pp. 484-494
    • Sawyer, J.R.1    Tian, E.2    Thomas, E.3
  • 23
    • 84899046793 scopus 로고    scopus 로고
    • Jumping translocations of 1q12 in multiple myeloma: A novel mechanism for deletion of 17p in cytogenetically defined high-risk disease
    • Sawyer JR, Tian E, Heuck CJ, et al. Jumping translocations of 1q12 in multiple myeloma: a novel mechanism for deletion of 17p in cytogenetically defined high-risk disease. Blood. 2014;123(16):2504-2512.
    • (2014) Blood. , vol.123 , Issue.16 , pp. 2504-2512
    • Sawyer, J.R.1    Tian, E.2    Heuck, C.J.3
  • 24
    • 36148955443 scopus 로고    scopus 로고
    • Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma
    • Jenner MW, Leone PE, Walker BA, et al. Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma. Blood. 2007;110(9): 3291-3300.
    • (2007) Blood , vol.110 , Issue.9 , pp. 3291-3300
    • Jenner, M.W.1    Leone, P.E.2    Walker, B.A.3
  • 25
    • 84863770814 scopus 로고    scopus 로고
    • Cancer genetics and epigenetics: Two sides of the same coin?
    • You JS, Jones PA. Cancer genetics and epigenetics: two sides of the same coin? Cancer Cell. 2012;22(1):9-20.
    • (2012) Cancer Cell. , vol.22 , Issue.1 , pp. 9-20
    • You, J.S.1    Jones, P.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.