In-vitro and in-vivo evaluation of taste-masked cetirizine hydrochloride formulated in oral lyophilisates

International Journal of Pharmaceutics

Volumn 491, Issue 1-2, 2015, Pages 8-16

  Preis, Maren ^a,b   Grother, Leon ^c   Axe, Philip ^c   Breitkreutz, Jörg ^b  

^a ÅBO AKADEMI UNIVERSITY   (Finland)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c CATALENT PHARMA SOLUTIONS   (United States)

Author keywords

Electronic tongue; Oral lyophilisate; Orally disintegrating tablet; Orodispersible tablet; Taste trial; Taste masking

Indexed keywords

ALUMINUM; CETIRIZINE; CYCLODEXTRIN; EXCIPIENT; ION EXCHANGE RESIN; BETA CYCLODEXTRIN; BETA CYCLODEXTRIN DERIVATIVE; SUCROSE; TABLET; TRICHLOROSUCROSE;

ARTICLE; BITTER TASTE; BLISTER PACK; CHEMICAL MODIFICATION; CONTROLLED STUDY; DISPERSION; DISSOLUTION; DRUG FORMULATION; ELECTRONIC SENSOR; EVALUATION STUDY; FREEZE DRYING; IN VITRO STUDY; IN VIVO STUDY; LYOPHILISATE; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; TASTE; VIBROTACTILE MASKING; ADOLESCENT; ADULT; ANALOGS AND DERIVATIVES; CHEMISTRY; FEMALE; HUMAN; MALE; MEDICINAL CHEMISTRY; MIDDLE AGED; ORAL DRUG ADMINISTRATION; PHYSIOLOGY; PROCEDURES; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; SOLUBILITY; SWEET CHERRY; TABLET; TONGUE; YOUNG ADULT;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; BETA-CYCLODEXTRINS; CETIRIZINE; CHEMISTRY, PHARMACEUTICAL; CYCLODEXTRINS; EXCIPIENTS; FEMALE; FREEZE DRYING; HUMANS; ION EXCHANGE RESINS; MALE; MIDDLE AGED; PRUNUS AVIUM; SINGLE-BLIND METHOD; SOLUBILITY; SUCROSE; TABLETS; TASTE; TONGUE; YOUNG ADULT;

EID: 84931275620     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.06.002     Document Type: Article

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