Generation of Broad-Spectrum Antifungal Drug Candidates from the Natural Product Compound Aureobasidin A

ACS Medicinal Chemistry Letters

Volumn 6, Issue 6, 2015, Pages 645-649

  Wuts, Peter G M ^a   Simons, Lloyd J ^a   Metzger, Brian P ^b   Sterling, Rachel C ^b   Slightom, Jerry L ^b   Elhammer, Ake P ^b  

^a Kalexsyn Inc   (United States)

^b AureoGen Biosciences Inc   (United States)

Author keywords

antifungal; aureobasidin A; C H borylation; SAR

Indexed keywords

ACETAMIDE DERIVATIVE; AMINO ACID; AUREOBASIDIN A; BROMINE DERIVATIVE; HYDROCHLORIC ACID;

ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS FUMIGATUS; COVALENT BOND; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; LARGE SCALE PRODUCTION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; SUZUKI REACTION;

ANIMALIA; ASPERGILLUS FUMIGATUS; FUNGI;

EID: 84931268380     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/acsmedchemlett.5b00029     Document Type: Article

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