-
1
-
-
84905721813
-
Whole-exome and targeted gene sequencing of gallbladder carcinoma identifies recurrent mutations in the ErbB pathway
-
1:CAS:528:DC%2BC2cXhtFSlsL3M 24997986
-
Li M, Zhang Z, Li X, Ye J, Wu X, Tan Z, et al. Whole-exome and targeted gene sequencing of gallbladder carcinoma identifies recurrent mutations in the ErbB pathway. Nat Genet. 2014;46(8):872-6.
-
(2014)
Nat Genet
, vol.46
, Issue.8
, pp. 872-876
-
-
Li, M.1
Zhang, Z.2
Li, X.3
Ye, J.4
Wu, X.5
Tan, Z.6
-
2
-
-
84896543721
-
Molecular characterization of gallbladder cancer using somatic mutation profiling
-
1:CAS:528:DC%2BC2cXitV2isr4%3D 4428571 24508317
-
Javle M, Rashid A, Churi C, Kar S, Zuo M, Eterovic AK, et al. Molecular characterization of gallbladder cancer using somatic mutation profiling. Hum Pathol. 2014;45(4):701-8.
-
(2014)
Hum Pathol
, vol.45
, Issue.4
, pp. 701-708
-
-
Javle, M.1
Rashid, A.2
Churi, C.3
Kar, S.4
Zuo, M.5
Eterovic, A.K.6
-
3
-
-
84890254448
-
Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update. American Society of Clinical Oncology; College of American Pathologists
-
24101045
-
Wolff AC, Hammond ME, Hicks DG, Dowsett M, McShane LM, Allison KH, et al. Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update. American Society of Clinical Oncology; College of American Pathologists. J Clin Oncol. 2013;31(31):3997-4013.
-
(2013)
J Clin Oncol
, vol.31
, Issue.31
, pp. 3997-4013
-
-
Wolff, A.C.1
Hammond, M.E.2
Hicks, D.G.3
Dowsett, M.4
McShane, L.M.5
Allison, K.H.6
-
4
-
-
84899802437
-
Overexpression of the HER2/neu gene: A new therapeutic possibility for patients with advanced gallbladder cancer
-
Roa I, de Toro G, Schalper K, de Aretxabala X, Churi C, Javle M. Overexpression of the HER2/neu gene: a new therapeutic possibility for patients with advanced gallbladder cancer. Gastrointestinal Cancer Res. 2014;7(2):42-8.
-
(2014)
Gastrointestinal Cancer Res
, vol.7
, Issue.2
, pp. 42-48
-
-
Roa, I.1
De Toro, G.2
Schalper, K.3
De Aretxabala, X.4
Churi, C.5
Javle, M.6
-
5
-
-
84919800397
-
Mutation profiling in cholangiocarcinoma: Prognostic and therapeutic implications
-
4275227 25536104
-
Churi CR, Shroff R, Wang Y, Rashid A, Kang HC, Weatherly J, et al. Mutation profiling in cholangiocarcinoma: prognostic and therapeutic implications. PLoS One. 2014;9(12), e115383.
-
(2014)
PLoS One
, vol.9
, Issue.12
-
-
Churi, C.R.1
Shroff, R.2
Wang, Y.3
Rashid, A.4
Kang, H.C.5
Weatherly, J.6
-
6
-
-
34447301537
-
Gene amplification and protein overexpression of HER-2/neu in human extrahepatic cholangiocarcinoma as detected by chromogenic in situ hybridization and immunohistochemistry: Its prognostic implication in node-positive patients
-
1:STN:280:DC%2BD2szoslegsQ%3D%3D 17322545
-
Kim HJ, Yoo TW, Park DI, Park JH, Cho YK, Sohn CI, et al. Gene amplification and protein overexpression of HER-2/neu in human extrahepatic cholangiocarcinoma as detected by chromogenic in situ hybridization and immunohistochemistry: its prognostic implication in node-positive patients. Ann Oncol. 2007;18(5):892-7.
-
(2007)
Ann Oncol
, vol.18
, Issue.5
, pp. 892-897
-
-
Kim, H.J.1
Yoo, T.W.2
Park, D.I.3
Park, J.H.4
Cho, Y.K.5
Sohn, C.I.6
-
7
-
-
0032951925
-
Overexpression of C-NEU and C-MET during rat liver cholangiocarcinogenesis: A link between biliary intestinal metaplasia and mucin-producing cholangiocarcinoma
-
1:CAS:528:DyaK1MXjt1Wnu7w%3D 10216129
-
Radaeva S, Ferreira-Gonzalez A, Sirica AE. Overexpression of C-NEU and C-MET during rat liver cholangiocarcinogenesis: a link between biliary intestinal metaplasia and mucin-producing cholangiocarcinoma. Hepatology. 1999;29(5):1453-62.
-
(1999)
Hepatology
, vol.29
, Issue.5
, pp. 1453-1462
-
-
Radaeva, S.1
Ferreira-Gonzalez, A.2
Sirica, A.E.3
-
8
-
-
0036623359
-
Gene amplification and mRNA and protein overexpression of c-erbB-2 (HER-2/neu) in human intrahepatic cholangiocarcinoma as detected by fluorescence in situ hybridization, in situ hybridization, and immunohistochemistry
-
1:CAS:528:DC%2BD38XktVCktLw%3D 12044528
-
Ukita Y, Kato M, Terada T. Gene amplification and mRNA and protein overexpression of c-erbB-2 (HER-2/neu) in human intrahepatic cholangiocarcinoma as detected by fluorescence in situ hybridization, in situ hybridization, and immunohistochemistry. J Hepatol. 2002;36(6):780-5.
-
(2002)
J Hepatol
, vol.36
, Issue.6
, pp. 780-785
-
-
Ukita, Y.1
Kato, M.2
Terada, T.3
-
9
-
-
79251644460
-
HER2: Biology, detection, and clinical implications
-
3242418 21204711
-
Gutierrez C, Schiff R. HER2: biology, detection, and clinical implications. Arch Pathol Lab Med. 2011;135(1):55-62.
-
(2011)
Arch Pathol Lab Med
, vol.135
, Issue.1
, pp. 55-62
-
-
Gutierrez, C.1
Schiff, R.2
-
10
-
-
79551694006
-
Associations of breast cancer risk factors with tumor subtypes: A pooled analysis from the Breast Cancer Association Consortium studies
-
3107570 21191117
-
Yang XR, Chang-Claude J, Goode EL, Couch FJ, Nevanlinna H, Milne RL, et al. Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies. J Natl Cancer Inst. 2011;103(3):250-63.
-
(2011)
J Natl Cancer Inst
, vol.103
, Issue.3
, pp. 250-263
-
-
Yang, X.R.1
Chang-Claude, J.2
Goode, E.L.3
Couch, F.J.4
Nevanlinna, H.5
Milne, R.L.6
-
11
-
-
84859903908
-
Clinicopathologic factors associated with HER2-positive gastric cancer and its impact on survival outcomes - A systematic review
-
1:CAS:528:DC%2BC3MXhsVOkt7bE
-
Chua TC, Merrett ND. Clinicopathologic factors associated with HER2-positive gastric cancer and its impact on survival outcomes - a systematic review. Int J Cancer J Int Du Cancer. 2012;130(12):2845-56.
-
(2012)
Int J Cancer J Int Du Cancer
, vol.130
, Issue.12
, pp. 2845-2856
-
-
Chua, T.C.1
Merrett, N.D.2
-
12
-
-
84877355892
-
HER2 expression beyond breast cancer: Therapeutic implications for gynecologic malignancies
-
1:CAS:528:DC%2BC3sXhvVajur%2FF
-
English DP, Roque DM, Santin AD. HER2 expression beyond breast cancer: therapeutic implications for gynecologic malignancies. Mol Diag Ther. 2013;17(2):85-99.
-
(2013)
Mol Diag Ther
, vol.17
, Issue.2
, pp. 85-99
-
-
English, D.P.1
Roque, D.M.2
Santin, A.D.3
-
13
-
-
79956069238
-
HER2 and gastric cancer. Recommendations for clinical practice in 2011
-
21601111
-
Penault-Llorca F, Chenard MP, Bouche O, Emile JF, Bibeau F, Metges JP, et al. HER2 and gastric cancer. Recommendations for clinical practice in 2011. Ann Pathol. 2011;31(2):78-87.
-
(2011)
Ann Pathol
, vol.31
, Issue.2
, pp. 78-87
-
-
Penault-Llorca, F.1
Chenard, M.P.2
Bouche, O.3
Emile, J.F.4
Bibeau, F.5
Metges, J.P.6
-
14
-
-
84891628913
-
HER2-positive gastric cancer
-
1:CAS:528:DC%2BC3sXitVWit7nJ 3889288 23563986
-
Boku N. HER2-positive gastric cancer. Gastric Cancer. 2014;17:1-12.
-
(2014)
Gastric Cancer.
, vol.17
, pp. 1-12
-
-
Boku, N.1
-
15
-
-
84877310973
-
The predictive role of phosphatase and tensin homolog (PTEN) loss, phosphoinositol-3 (PI3) kinase (PIK3CA) mutation, and PI3K pathway activation in sensitivity to trastuzumab in HER2-positive breast cancer: A meta-analysis
-
1:CAS:528:DC%2BC3sXntFylt7g%3D 23574264
-
Wang Y, Liu Y, Du Y, Yin W, Lu J. The predictive role of phosphatase and tensin homolog (PTEN) loss, phosphoinositol-3 (PI3) kinase (PIK3CA) mutation, and PI3K pathway activation in sensitivity to trastuzumab in HER2-positive breast cancer: a meta-analysis. Curr Med Res Opin. 2013;29(6):633-42.
-
(2013)
Curr Med Res Opin
, vol.29
, Issue.6
, pp. 633-642
-
-
Wang, Y.1
Liu, Y.2
Du, Y.3
Yin, W.4
Lu, J.5
-
16
-
-
0027165366
-
Shc products are substrates of erbB-2 kinase
-
1:CAS:528:DyaK3sXlslKnsL4%3D 8101647
-
Segatto O, Pelicci G, Giuli S, Digiesi G, Di Fiore PP, McGlade J, et al. Shc products are substrates of erbB-2 kinase. Oncogene. 1993;8(8):2105-12.
-
(1993)
Oncogene
, vol.8
, Issue.8
, pp. 2105-2112
-
-
Segatto, O.1
Pelicci, G.2
Giuli, S.3
Digiesi, G.4
Di Fiore, P.P.5
McGlade, J.6
-
17
-
-
84859399146
-
Targeted therapy in the management of advanced gastric cancer: Are we making progress in the era of personalized medicine?
-
1:CAS:528:DC%2BC38XmvVehsbo%3D 3316920 22334453
-
Wong H, Yau T. Targeted therapy in the management of advanced gastric cancer: are we making progress in the era of personalized medicine? Oncologist. 2012;17(3):346-58.
-
(2012)
Oncologist
, vol.17
, Issue.3
, pp. 346-358
-
-
Wong, H.1
Yau, T.2
-
18
-
-
84868560972
-
Impact of expression of human epidermal growth factor receptors EGFR and ERBB2 on survival in stage II/III gastric cancer
-
1:CAS:528:DC%2BC38Xhs1GhtrvF 22977193
-
Terashima M, Kitada K, Ochiai A, Ichikawa W, Kurahashi I, Sakuramoto S, et al. Impact of expression of human epidermal growth factor receptors EGFR and ERBB2 on survival in stage II/III gastric cancer. Clin Cancer Res. 2012;18(21):5992-6000.
-
(2012)
Clin Cancer Res
, vol.18
, Issue.21
, pp. 5992-6000
-
-
Terashima, M.1
Kitada, K.2
Ochiai, A.3
Ichikawa, W.4
Kurahashi, I.5
Sakuramoto, S.6
-
19
-
-
84893750117
-
Next-generation sequencing-based multi-gene mutation profiling of solid tumors using fine needle aspiration samples: Promises and challenges for routine clinical diagnostics
-
1:CAS:528:DC%2BC2cXhsl2jsr8%3D
-
Kanagal-Shamanna R, Portier BP, Singh RR, Routbort MJ, Aldape KD, Handal BA, et al. Next-generation sequencing-based multi-gene mutation profiling of solid tumors using fine needle aspiration samples: promises and challenges for routine clinical diagnostics. Modern Pathol. 2014;27(2):314-27.
-
(2014)
Modern Pathol
, vol.27
, Issue.2
, pp. 314-327
-
-
Kanagal-Shamanna, R.1
Portier, B.P.2
Singh, R.R.3
Routbort, M.J.4
Aldape, K.D.5
Handal, B.A.6
-
20
-
-
80053508491
-
Whole cancer genome sequencing by next-generation methods
-
1:CAS:528:DC%2BC3MXhtlKjsL%2FL 21917674
-
Ross JS, Cronin M. Whole cancer genome sequencing by next-generation methods. Am J Clin Pathol. 2011;136(4):527-39.
-
(2011)
Am J Clin Pathol
, vol.136
, Issue.4
, pp. 527-539
-
-
Ross, J.S.1
Cronin, M.2
-
21
-
-
59849113821
-
Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing
-
1:CAS:528:DC%2BD1MXht1ehs7o%3D 2663421 19182786
-
Gnirke A, Melnikov A, Maguire J, Rogov P, LeProust EM, Brockman W, et al. Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing. Nat Biotechnol. 2009;27(2):182-9.
-
(2009)
Nat Biotechnol
, vol.27
, Issue.2
, pp. 182-189
-
-
Gnirke, A.1
Melnikov, A.2
Maguire, J.3
Rogov, P.4
LeProust, E.M.5
Brockman, W.6
-
22
-
-
65649135081
-
Implementation of American Society of Clinical Oncology/College of American Pathologists HER2 guideline recommendations in a tertiary care facility increases HER2 immunohistochemistry and fluorescence in situ hybridization concordance and decreases the number of inconclusive cases
-
19415952
-
Middleton LP, Price KM, Puig P, Heydon LJ, Tarco E, Sneige N, et al. Implementation of American Society of Clinical Oncology/College of American Pathologists HER2 guideline recommendations in a tertiary care facility increases HER2 immunohistochemistry and fluorescence in situ hybridization concordance and decreases the number of inconclusive cases. Arch Pathol Lab Med. 2009;133(5):775-80.
-
(2009)
Arch Pathol Lab Med
, vol.133
, Issue.5
, pp. 775-780
-
-
Middleton, L.P.1
Price, K.M.2
Puig, P.3
Heydon, L.J.4
Tarco, E.5
Sneige, N.6
-
23
-
-
28644441429
-
FAT, E-cadherin, beta catenin, HER 2/neu, Ki67 immuno-expression, and histological grade in intrahepatic cholangiocarcinoma
-
1:CAS:528:DC%2BD28Xjs1Gjsg%3D%3D 1770788 16311342
-
Settakorn J, Kaewpila N, Burns GF, Leong AS. FAT, E-cadherin, beta catenin, HER 2/neu, Ki67 immuno-expression, and histological grade in intrahepatic cholangiocarcinoma. J Clin Pathol. 2005;58(12):1249-54.
-
(2005)
J Clin Pathol
, vol.58
, Issue.12
, pp. 1249-1254
-
-
Settakorn, J.1
Kaewpila, N.2
Burns, G.F.3
Leong, A.S.4
-
24
-
-
21344438897
-
Amplification and overexpression of c-erbB-2, epidermal growth factor receptor, and c-met in biliary tract cancers
-
1:CAS:528:DC%2BD2MXmvVartb0%3D 15892172
-
Nakazawa K, Dobashi Y, Suzuki S, Fujii H, Takeda Y, Ooi A. Amplification and overexpression of c-erbB-2, epidermal growth factor receptor, and c-met in biliary tract cancers. J Pathol. 2005;206(3):356-65.
-
(2005)
J Pathol
, vol.206
, Issue.3
, pp. 356-365
-
-
Nakazawa, K.1
Dobashi, Y.2
Suzuki, S.3
Fujii, H.4
Takeda, Y.5
Ooi, A.6
-
25
-
-
38549139744
-
Clinicopathological and prognostic significance of EGFR, VEGF, and HER2 expression in cholangiocarcinoma
-
1:CAS:528:DC%2BD1cXhtVKjsr8%3D 2361442 18087285
-
Yoshikawa D, Ojima H, Iwasaki M, Hiraoka N, Kosuge T, Kasai S, et al. Clinicopathological and prognostic significance of EGFR, VEGF, and HER2 expression in cholangiocarcinoma. Br J Cancer. 2008;98(2):418-25.
-
(2008)
Br J Cancer
, vol.98
, Issue.2
, pp. 418-425
-
-
Yoshikawa, D.1
Ojima, H.2
Iwasaki, M.3
Hiraoka, N.4
Kosuge, T.5
Kasai, S.6
-
26
-
-
77649339494
-
Epidermal growth factor receptor and HER-2/neu status by immunohistochemistry and fluorescence in situ hybridization in adenocarcinomas of the biliary tree and gallbladder
-
1:CAS:528:DC%2BC3cXjtFyitbY%3D 20040392
-
Shafizadeh N, Grenert JP, Sahai V, Kakar S. Epidermal growth factor receptor and HER-2/neu status by immunohistochemistry and fluorescence in situ hybridization in adenocarcinomas of the biliary tree and gallbladder. Hum Pathol. 2010;41(4):485-92.
-
(2010)
Hum Pathol
, vol.41
, Issue.4
, pp. 485-492
-
-
Shafizadeh, N.1
Grenert, J.P.2
Sahai, V.3
Kakar, S.4
-
27
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
1:CAS:528:DC%2BD3MXisVGktrc%3D 11248153
-
Slamon DJ, Leyland-Jones B, Shak S, Fuchs H, Paton V, Bajamonde A, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med. 2001;344(11):783-92.
-
(2001)
N Engl J Med
, vol.344
, Issue.11
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
Fuchs, H.4
Paton, V.5
Bajamonde, A.6
-
28
-
-
84862914692
-
Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer
-
1:CAS:528:DC%2BC38XhtFSlt7Y%3D 22149875
-
Baselga J, Cortes J, Kim SB, Im SA, Hegg R, Im YH, et al. Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer. N Engl J Med. 2012;366(2):109-19.
-
(2012)
N Engl J Med
, vol.366
, Issue.2
, pp. 109-119
-
-
Baselga, J.1
Cortes, J.2
Kim, S.B.3
Im, S.A.4
Hegg, R.5
Im, Y.H.6
-
29
-
-
84868520609
-
Trastuzumab emtansine for HER2-positive advanced breast cancer
-
1:CAS:528:DC%2BC38Xhs1ekt73M 23020162
-
Verma S, Miles D, Gianni L, Krop IE, Welslau M, Baselga J, et al. Trastuzumab emtansine for HER2-positive advanced breast cancer. N Engl J Med. 2012;367(19):1783-91.
-
(2012)
N Engl J Med
, vol.367
, Issue.19
, pp. 1783-1791
-
-
Verma, S.1
Miles, D.2
Gianni, L.3
Krop, I.E.4
Welslau, M.5
Baselga, J.6
-
30
-
-
77956262693
-
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial
-
1:CAS:528:DC%2BC3cXhtVymt7zO 20728210
-
Bang YJ, Van Cutsem E, Feyereislova A, Chung HC, Shen L, Sawaki A, et al. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet. 2010;376(9742):687-97.
-
(2010)
Lancet
, vol.376
, Issue.9742
, pp. 687-697
-
-
Bang, Y.J.1
Van Cutsem, E.2
Feyereislova, A.3
Chung, H.C.4
Shen, L.5
Sawaki, A.6
-
31
-
-
84866771822
-
Dramatic response to trastuzumab and paclitaxel in a patient with human epidermal growth factor receptor 2-positive metastatic cholangiocarcinoma
-
22851567
-
Law LY. Dramatic response to trastuzumab and paclitaxel in a patient with human epidermal growth factor receptor 2-positive metastatic cholangiocarcinoma. J Clin Oncol. 2012;30(27):e271-3.
-
(2012)
J Clin Oncol
, vol.30
, Issue.27
, pp. e271-e273
-
-
Law, L.Y.1
-
32
-
-
84890333881
-
Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab
-
Sorscher S. Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab. Cancer Manag Res. 2014;6:1-3.
-
(2014)
Cancer Manag Res.
, vol.6
, pp. 1-3
-
-
Sorscher, S.1
-
33
-
-
79953162369
-
Switching addictions between HER2 and FGFR2 in HER2-positive breast tumor cells: FGFR2 as a potential target for salvage after lapatinib failure
-
1:CAS:528:DC%2BC3MXkt1KjtLw%3D 21377448
-
Azuma K, Tsurutani J, Sakai K, Kaneda H, Fujisaka Y, Takeda M, et al. Switching addictions between HER2 and FGFR2 in HER2-positive breast tumor cells: FGFR2 as a potential target for salvage after lapatinib failure. Biochem Biophys Res Commun. 2011;407(1):219-24.
-
(2011)
Biochem Biophys Res Commun
, vol.407
, Issue.1
, pp. 219-224
-
-
Azuma, K.1
Tsurutani, J.2
Sakai, K.3
Kaneda, H.4
Fujisaka, Y.5
Takeda, M.6
-
34
-
-
84873918443
-
Activating HER2 mutations in HER2 gene amplification negative breast cancer
-
1:CAS:528:DC%2BC3sXis1Wktrg%3D 3570596 23220880
-
Bose R, Kavuri SM, Searleman AC, Shen W, Shen D, Koboldt DC, et al. Activating HER2 mutations in HER2 gene amplification negative breast cancer. Cancer Discov. 2013;3(2):224-37.
-
(2013)
Cancer Discov
, vol.3
, Issue.2
, pp. 224-237
-
-
Bose, R.1
Kavuri, S.M.2
Searleman, A.C.3
Shen, W.4
Shen, D.5
Koboldt, D.C.6
-
35
-
-
65349101151
-
Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941
-
1:CAS:528:DC%2BD1MXmvVGitrg%3D 19411071
-
Junttila TT, Akita RW, Parsons K, Fields C, Lewis Phillips GD, Friedman LS, et al. Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941. Cancer Cell. 2009;15(5):429-40.
-
(2009)
Cancer Cell
, vol.15
, Issue.5
, pp. 429-440
-
-
Junttila, T.T.1
Akita, R.W.2
Parsons, K.3
Fields, C.4
Lewis Phillips, G.D.5
Friedman, L.S.6
-
36
-
-
79551682846
-
Mutational profiling reveals PIK3CA mutations in gallbladder carcinoma
-
3045359 21303542
-
Deshpande V, Nduaguba A, Zimmerman SM, Kehoe SM, Macconaill LE, Lauwers GY, et al. Mutational profiling reveals PIK3CA mutations in gallbladder carcinoma. BMC Cancer. 2011;11:60.
-
(2011)
BMC Cancer.
, vol.11
, pp. 60
-
-
Deshpande, V.1
Nduaguba, A.2
Zimmerman, S.M.3
Kehoe, S.M.4
Macconaill, L.E.5
Lauwers, G.Y.6
|