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Volumn 17, Issue 2, 2013, Pages 85-99

HER2 expression beyond breast cancer: Therapeutic implications for gynecologic malignancies

Author keywords

[No Author keywords available]

Indexed keywords

1 (1 CYANO 1 METHYLETHYL) 3 METHYL 8 (3 QUINOLINYL)IMIDAZO[4,5 C]QUINOLIN 2(1H,3H) ONE; 2 (4 HYDROXYPHENYL) 4 MORPHOLINOPYRIDO[3',2':4,5]FURO[3,2 D]PYRIMIDINE; 8 [4 (1 AMINOCYCLOBUTYL)PHENYL] 9 PHENYL 1,2,4 TRIAZOLO[3,4 F][1,6]NAPHTHYRIDIN 3(2H) ONE; AFATINIB; APITOLISIB; BUPARLISIB; CANERTINIB; CARBOPLATIN; CYCLOPHOSPHAMIDE; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EVEROLIMUS; HER2 VACCINE; IDELALISIB; LAPATINIB; LEAD 212; LUMINESPIB; MARGETUXIMAB; NERATINIB; PACLITAXEL; PERTUZUMAB; PICTILISIB; PROTEIN TYROSINE KINASE INHIBITOR; RECOMBINANT INTERLEUKIN 2; RETASPIMYCIN; TANESPIMYCIN; TRASTUZUMAB; TRASTUZUMAB EMTANSINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84877355892     PISSN: 11771062     EISSN: 11792000     Source Type: Journal    
DOI: 10.1007/s40291-013-0024-9     Document Type: Review
Times cited : (161)

References (129)
  • 1
    • 0035170259 scopus 로고    scopus 로고
    • Anticancer therapy targeting the erbB family of receptor tyrosine kinases
    • Slichenmyer WJ, Fry DW. Anticancer therapy targeting the erbB family of receptor tyrosine kinases. Semin Oncol. 2001;28(5 Suppl 16):67-79. Epub 2001 Nov 14. (Pubitemid 33065112)
    • (2001) Seminars in Oncology , vol.28 , Issue.5 , pp. 67-79
    • Slichenmyer, W.J.1    Fry, D.W.2
  • 2
    • 29844454750 scopus 로고    scopus 로고
    • Long-term prognostic significance of HER-2/neu in untreated node-negative breast cancer depends on the method of testing
    • 15743506 1:CAS:528:DC%2BD2MXhslyjtbw%3D Epub 2005 Mar 4
    • Schmidt M, Lewark B, Kohlschmidt N, Glawatz C, Steiner E, Tanner B, et al. Long-term prognostic significance of HER-2/neu in untreated node-negative breast cancer depends on the method of testing. Breast Cancer Res. 2005;7(2):R256-66. Epub 2005 Mar 4.
    • (2005) Breast Cancer Res , vol.7 , Issue.2
    • Schmidt, M.1    Lewark, B.2    Kohlschmidt, N.3    Glawatz, C.4    Steiner, E.5    Tanner, B.6
  • 3
    • 0031684721 scopus 로고    scopus 로고
    • The HER-2/neu oncogene in breast cancer: Prognostic factor, predictive factor, and target for therapy
    • 10388110 Epub 1999 Jul 1
    • Ross JS, Fletcher JA. The HER-2/neu oncogene in breast cancer: prognostic factor, predictive factor, and target for therapy. Oncologist. 1998;3(4):237-52. Epub 1999 Jul 1.
    • (1998) Oncologist , vol.3 , Issue.4 , pp. 237-252
    • Ross, J.S.1    Fletcher, J.A.2
  • 4
    • 77956070565 scopus 로고    scopus 로고
    • Anti-HER2 vaccines: New prospects for breast cancer therapy
    • 20532501 1:CAS:528:DC%2BC3cXotVOlurk%3D Epub 2010 Jun 10
    • Ladjemi MZ, Jacot W, Chardes T, Pelegrin A, Navarro-Teulon I. Anti-HER2 vaccines: new prospects for breast cancer therapy. Cancer Immunol Immunother. 2010;59(9):1295-312. Epub 2010 Jun 10.
    • (2010) Cancer Immunol Immunother , vol.59 , Issue.9 , pp. 1295-1312
    • Ladjemi, M.Z.1    Jacot, W.2    Chardes, T.3    Pelegrin, A.4    Navarro-Teulon, I.5
  • 5
    • 0028670125 scopus 로고
    • The biology of erbB-2/neu/HER-2 and its role in cancer
    • 7819273 Epub 1994 Dec 30
    • Hynes NE, Stern DF. The biology of erbB-2/neu/HER-2 and its role in cancer. Biochimi Biophys Acta. 1994;1198(2-3):165-84. Epub 1994 Dec 30.
    • (1994) Biochim Biophys Acta , vol.1198 , Issue.2-3 , pp. 165-184
    • Hynes, N.E.1    Stern, D.F.2
  • 6
    • 0029039990 scopus 로고
    • The c-erbB-2 proto-oncogene as a prognostic and predictive marker in breast cancer: A paradigm for the development of other macromolecular markers - A review
    • 7607568 1:CAS:528:DyaK2MXmvFWru78%3D Epub 1995 Jun 14
    • Ravdin PM, Chamness GC. The c-erbB-2 proto-oncogene as a prognostic and predictive marker in breast cancer: a paradigm for the development of other macromolecular markers - a review. Gene. 1995;159(1):19-27. Epub 1995 Jun 14.
    • (1995) Gene , vol.159 , Issue.1 , pp. 19-27
    • Ravdin, P.M.1    Chamness, G.C.2
  • 7
    • 3442890204 scopus 로고    scopus 로고
    • Role of HER receptors family in development and differentiation
    • DOI 10.1002/jcp.20007
    • Casalini P, Iorio MV, Galmozzi E, Menard S. Role of HER receptors family in development and differentiation. J Cell Physiol. 2004;200(3):343-50. Epub 2004 Jul 16. (Pubitemid 39006925)
    • (2004) Journal of Cellular Physiology , vol.200 , Issue.3 , pp. 343-350
    • Casalini, P.1    Iorio, M.V.2    Galmozzi, E.3    Menard, S.4
  • 9
    • 0030944455 scopus 로고    scopus 로고
    • ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
    • DOI 10.1093/emboj/16.7.1647
    • Graus-Porta D, Beerli RR, Daly JM, Hynes NE. ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling. EMBO J. 1997;16(7):1647-55. Epub 1997 Apr 1. (Pubitemid 27151960)
    • (1997) EMBO Journal , vol.16 , Issue.7 , pp. 1647-1655
    • Graus-Porta, D.1    Beerli, R.R.2    Daly, J.M.3    Hynes, N.E.4
  • 10
    • 0034473028 scopus 로고    scopus 로고
    • Her-2/neu (erbB-2) and the cell cycle
    • Busse D, Doughty RS, Arteaga CL. HER-2/neu (erbB-2) and the cell cycle. Semin Oncol. 2000;27(6 Suppl 11):3-8; discussion 92-100. Epub 2001 Mar 10. (Pubitemid 32172249)
    • (2000) Seminars in Oncology , vol.27 , Issue.6 , pp. 3-8
    • Busse, D.1    Doughty, R.S.2    Arteaga, C.L.3
  • 12
    • 79961024637 scopus 로고    scopus 로고
    • Targeting the human EGFR family in esophagogastric cancer
    • 21468131 1:CAS:528:DC%2BC3MXpsFKgs74%3D Epub 2011 Apr 7
    • Okines A, Cunningham D, Chau I. Targeting the human EGFR family in esophagogastric cancer. Nat Rev Clin Oncol. 2011;8(8):492-503. Epub 2011 Apr 7.
    • (2011) Nat Rev Clin Oncol , vol.8 , Issue.8 , pp. 492-503
    • Okines, A.1    Cunningham, D.2    Chau, I.3
  • 13
    • 33645907542 scopus 로고    scopus 로고
    • Prognostic, predictive and therapeutic implications of HER2 in invasive epithelial ovarian cancer
    • 16483720 1:CAS:528:DC%2BD28XjvFSgtro%3D Epub 2006 Feb 18
    • Serrano-Olvera A, Duenas-Gonzalez A, Gallardo-Rincon D, Candelaria M, De la Garza-Salazar J. Prognostic, predictive and therapeutic implications of HER2 in invasive epithelial ovarian cancer. Cancer Treat Rev. 2006;32(3):180-90. Epub 2006 Feb 18.
    • (2006) Cancer Treat Rev , vol.32 , Issue.3 , pp. 180-190
    • Serrano-Olvera, A.1    Duenas-Gonzalez, A.2    Gallardo-Rincon, D.3    Candelaria, M.4    De La Garza-Salazar, J.5
  • 14
    • 70349577111 scopus 로고    scopus 로고
    • Emerging technologies for assessing HER2 amplification
    • 19762531 1:CAS:528:DC%2BD1MXhtlSjtrbO Epub 2009 Sep 19
    • Penault-Llorca F, Bilous M, Dowsett M, Hanna W, Osamura RY, Ruschoff J, et al. Emerging technologies for assessing HER2 amplification. Am J Clin Pathol. 2009;132(4):539-48. Epub 2009 Sep 19.
    • (2009) Am J Clin Pathol , vol.132 , Issue.4 , pp. 539-548
    • Penault-Llorca, F.1    Bilous, M.2    Dowsett, M.3    Hanna, W.4    Osamura, R.Y.5    Ruschoff, J.6
  • 15
    • 77953044525 scopus 로고    scopus 로고
    • Silver in situ hybridization (SISH) for determination of HER2 gene status in breast carcinoma: Comparison with FISH and assessment of interobserver reproducibility
    • 20421783 Epub 2010 Apr 28
    • Papouchado BG, Myles J, Lloyd RV, Stoler M, Oliveira AM, Downs-Kelly E, et al. Silver in situ hybridization (SISH) for determination of HER2 gene status in breast carcinoma: comparison with FISH and assessment of interobserver reproducibility. Am J Surg Pathol. 2010;34(6):767-76. Epub 2010 Apr 28.
    • (2010) Am J Surg Pathol , vol.34 , Issue.6 , pp. 767-776
    • Papouchado, B.G.1    Myles, J.2    Lloyd, R.V.3    Stoler, M.4    Oliveira, A.M.5    Downs-Kelly, E.6
  • 16
    • 35748985896 scopus 로고    scopus 로고
    • Comparison of automated silver enhanced in situ hybridisation (SISH) and fluorescence ISH (FISH) for the validation of HER2 gene status in breast carcinoma according to the guidelines of the American Society of Clinical Oncology and the College of American Pathologists
    • 1:CAS:528:DC%2BD2sXpsVOiurk%3D Epub 2007 Jun 15
    • Dietel M, Ellis IO, Hofler H, Kreipe H, Moch H, Dankof A, et al. Comparison of automated silver enhanced in situ hybridisation (SISH) and fluorescence ISH (FISH) for the validation of HER2 gene status in breast carcinoma according to the guidelines of the American Society of Clinical Oncology and the College of American Pathologists. Virchows Arch Int J Pathol. 2007;451(1):19-25. Epub 2007 Jun 15.
    • (2007) Virchows Arch Int J Pathol , vol.451 , Issue.1 , pp. 19-25
    • Dietel, M.1    Ellis, I.O.2    Hofler, H.3    Kreipe, H.4    Moch, H.5    Dankof, A.6
  • 17
    • 0033785293 scopus 로고    scopus 로고
    • HER-2/neu assessment in breast cancer by immunohistochemistry and fluorescence in situ hybridization: Comparison of results and correlation with survival
    • 11070154 1:CAS:528:DC%2BD3cXnsVekurY%3D Epub 2000 Nov 9
    • Kakar S, Puangsuvan N, Stevens JM, Serenas R, Mangan G, Sahai S, et al. HER-2/neu assessment in breast cancer by immunohistochemistry and fluorescence in situ hybridization: comparison of results and correlation with survival. Mol Diagn. 2000;5(3):199-207. Epub 2000 Nov 9.
    • (2000) Mol Diagn , vol.5 , Issue.3 , pp. 199-207
    • Kakar, S.1    Puangsuvan, N.2    Stevens, J.M.3    Serenas, R.4    Mangan, G.5    Sahai, S.6
  • 20
    • 0026662284 scopus 로고
    • T-cell recognition of oncogene products: A new strategy for immunotherapy
    • 1382444 1:CAS:528:DyaK3sXlt1Wk Epub 1992 Jan 1
    • Ioannides CG, Ioannides MG, O'Brian CA. T-cell recognition of oncogene products: a new strategy for immunotherapy. Mol Carcinog. 1992;6(2):77-82. Epub 1992 Jan 1.
    • (1992) Mol Carcinog , vol.6 , Issue.2 , pp. 77-82
    • Ioannides, C.G.1    Ioannides, M.G.2    O'Brian, C.A.3
  • 22
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science. 1987;235(4785):177-82. Epub 1987 Jan 9. (Pubitemid 17231334)
    • (1987) Science , vol.235 , Issue.4785 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3
  • 24
    • 0027954359 scopus 로고
    • Prognostic significance of the overexpression of c-erbB-2 protein in adenocarcinoma of the uterine cervix
    • DOI 10.1002/1097-0142(19940101)73:1<148::AID-CNCR2820730125>3.0. CO;2-C
    • Kihana T, Tsuda H, Teshima S, Nomoto K, Tsugane S, Sonoda T, et al. Prognostic significance of the overexpression of c-erbB-2 protein in adenocarcinoma of the uterine cervix. Cancer. 1994;73(1):148-53. Epub 1994 Jan 1. (Pubitemid 24012735)
    • (1994) Cancer , vol.73 , Issue.1 , pp. 148-153
    • Kihana, T.1    Tsuda, H.2    Teshima, S.3    Nomoto, K.4    Tsugane, S.5    Sonoda, T.6    Matsuura, S.7    Hirohashi, S.8
  • 25
    • 84863617783 scopus 로고    scopus 로고
    • Discordant expression of hormone receptors and HER2 in breast cancer. A retrospective comparison of primary tumors with paired metachronous recurrences or metastases
    • 22740206 1:STN:280:DC%2BC38jlsV2htQ%3D%3D Epub 2012 Jun 29
    • Arapantoni-Dadioti P, Valavanis C, Gavressea T, Tzaida O, Trihia H, Lekka I. Discordant expression of hormone receptors and HER2 in breast cancer. A retrospective comparison of primary tumors with paired metachronous recurrences or metastases. J BUON. 2012;17(2):277-83. Epub 2012 Jun 29.
    • (2012) J BUON , vol.17 , Issue.2 , pp. 277-283
    • Arapantoni-Dadioti, P.1    Valavanis, C.2    Gavressea, T.3    Tzaida, O.4    Trihia, H.5    Lekka, I.6
  • 26
    • 79955468866 scopus 로고    scopus 로고
    • Comparison of HER2 status in primary and paired metastatic sites of gastric carcinoma
    • 21487407 1:STN:280:DC%2BC3MvmvFSgug%3D%3D Epub 2011 Apr 14
    • Bozzetti C, Negri FV, Lagrasta CA, Crafa P, Bassano C, Tamagnini I, et al. Comparison of HER2 status in primary and paired metastatic sites of gastric carcinoma. Br J Cancer. 2011;104(9):1372-6. Epub 2011 Apr 14.
    • (2011) Br J Cancer , vol.104 , Issue.9 , pp. 1372-1376
    • Bozzetti, C.1    Negri, F.V.2    Lagrasta, C.A.3    Crafa, P.4    Bassano, C.5    Tamagnini, I.6
  • 28
    • 3042737680 scopus 로고    scopus 로고
    • Subclassification of ovarian surface epithelial tumors based on correlation of histologic and molecular pathologic data
    • DOI 10.1097/01.pgp.0000130446.84670.93
    • Gilks CB. Subclassification of ovarian surface epithelial tumors based on correlation of histologic and molecular pathologic data. Int J Gynecol Pathol. 2004;23(3):200-5. Epub 2004 Jun 24. (Pubitemid 38857108)
    • (2004) International Journal of Gynecological Pathology , vol.23 , Issue.3 , pp. 200-205
    • Gilks, C.B.1
  • 29
    • 50249119572 scopus 로고    scopus 로고
    • Immunophenotyping of serous carcinoma of the female genital tract
    • 18567994 1:CAS:528:DC%2BD1cXhtVagsb7I Epub 2008 Jun 24
    • Nofech-Mozes S, Khalifa MA, Ismiil N, Saad RS, Hanna WM, Covens A, et al. Immunophenotyping of serous carcinoma of the female genital tract. Mod Pathol. 2008;21(9):1147-55. Epub 2008 Jun 24.
    • (2008) Mod Pathol , vol.21 , Issue.9 , pp. 1147-1155
    • Nofech-Mozes, S.1    Khalifa, M.A.2    Ismiil, N.3    Saad, R.S.4    Hanna, W.M.5    Covens, A.6
  • 31
    • 84859757842 scopus 로고    scopus 로고
    • Survival for ovarian cancer in Europe: The across-country variation did not shrink in the past decade
    • 22313338 Epub 2012 Feb 9
    • Oberaigner W, Minicozzi P, Bielska-Lasota M, Allemani C, De Angelis R, Mangone L, et al. Survival for ovarian cancer in Europe: the across-country variation did not shrink in the past decade. Acta Oncol. 2012;51(4):441-53. Epub 2012 Feb 9.
    • (2012) Acta Oncol , vol.51 , Issue.4 , pp. 441-453
    • Oberaigner, W.1    Minicozzi, P.2    Bielska-Lasota, M.3    Allemani, C.4    De Angelis, R.5    Mangone, L.6
  • 32
    • 0026484997 scopus 로고
    • Immunohistochemical localization of c-erbB-2 protein and epidermal growth factor receptor in normal surface epithelium, surface inclusion cysts, and common epithelial tumours of the ovary
    • 1360720 1:STN:280:DyaK3s%2FovVKjtg%3D%3D Epub 1992 Jan 1
    • Wang DP, Konishi I, Koshiyama M, Nanbu Y, Iwai T, Nonogaki H, et al. Immunohistochemical localization of c-erbB-2 protein and epidermal growth factor receptor in normal surface epithelium, surface inclusion cysts, and common epithelial tumours of the ovary. Virchows Arch A Pathol Anat Histopathol. 1992;421(5):393-400. Epub 1992 Jan 1.
    • (1992) Virchows Arch A Pathol Anat Histopathol , vol.421 , Issue.5 , pp. 393-400
    • Wang, D.P.1    Konishi, I.2    Koshiyama, M.3    Nanbu, Y.4    Iwai, T.5    Nonogaki, H.6
  • 33
    • 84867003075 scopus 로고    scopus 로고
    • EGFR, HER2/neu and Ki67 immunoexpression in serous ovarian tumors
    • 22990547 1:STN:280:DC%2BC38botF2lug%3D%3D Epub 2012 Sep 20
    • Marinas MC, Mogos G, Ciurea R, Mogos DG. EGFR, HER2/neu and Ki67 immunoexpression in serous ovarian tumors. Rom J Morphol Embryol. 2012;53(3):563-7. Epub 2012 Sep 20.
    • (2012) Rom J Morphol Embryol , vol.53 , Issue.3 , pp. 563-567
    • Marinas, M.C.1    Mogos, G.2    Ciurea, R.3    Mogos, D.G.4
  • 35
    • 0742272546 scopus 로고    scopus 로고
    • ERBB2 amplification is superior to protein expression status in predicting patient outcome in serous ovarian carcinoma
    • DOI 10.1016/j.ygyno.2003.10.010
    • Lassus H, Leminen A, Vayrynen A, Cheng G, Gustafsson JA, Isola J, et al. ERBB2 amplification is superior to protein expression status in predicting patient outcome in serous ovarian carcinoma. Gynecol Oncol. 2004;92(1):31-9. Epub 2004 Jan 31. (Pubitemid 38147368)
    • (2004) Gynecologic Oncology , vol.92 , Issue.1 , pp. 31-39
    • Lassus, H.1    Leminen, A.2    Vayrynen, A.3    Cheng, G.4    Gustafsson, J.-A.5    Isola, J.6    Butzow, R.7
  • 36
    • 9944239917 scopus 로고    scopus 로고
    • Her-2/neu expression and amplification in early stage ovarian surface epithelial neoplasms
    • DOI 10.1016/j.ygyno.2004.08.043, PII S0090825804006493
    • Wu Y, Soslow RA, Marshall DS, Leitao M, Chen B. Her-2/neu expression and amplification in early stage ovarian surface epithelial neoplasms. Gynecol Oncol. 2004;95(3):570-5. Epub 2004 Dec 8. (Pubitemid 39592523)
    • (2004) Gynecologic Oncology , vol.95 , Issue.3 , pp. 570-575
    • Wu, Y.1    Soslow, R.A.2    Marshall, D.S.3    Leitao, M.4    Chen, B.5
  • 37
    • 0037440042 scopus 로고    scopus 로고
    • Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: A phase II trial of the Gynecologic Oncology Group
    • DOI 10.1200/JCO.2003.10.104
    • Bookman MA, Darcy KM, Clarke-Pearson D, Boothby RA, Horowitz IR. Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: a phase II trial of the Gynecologic Oncology Group. J Clin Oncol. 2003;21(2):283-90. Epub 2003 Jan 15. (Pubitemid 46606157)
    • (2003) Journal of Clinical Oncology , vol.21 , Issue.2 , pp. 283-290
    • Bookman, M.A.1    Darcy, K.M.2    Clarke-Pearson, D.3    Boothby, R.A.4    Horowitz, I.R.5
  • 40
    • 74049094790 scopus 로고    scopus 로고
    • HER2 overexpression and amplification is present in a subset of ovarian mucinous carcinomas and can be targeted with trastuzumab therapy
    • 20003286 Epub 2009 Dec 17
    • McAlpine JN, Wiegand KC, Vang R, Ronnett BM, Adamiak A, Kobel M, et al. HER2 overexpression and amplification is present in a subset of ovarian mucinous carcinomas and can be targeted with trastuzumab therapy. BMC Cancer. 2009;9:433. Epub 2009 Dec 17.
    • (2009) BMC Cancer , vol.9 , pp. 433
    • McAlpine, J.N.1    Wiegand, K.C.2    Vang, R.3    Ronnett, B.M.4    Adamiak, A.5    Kobel, M.6
  • 41
    • 84872862768 scopus 로고    scopus 로고
    • Molecular characterization of mucinous ovarian tumors supports a stratified treatment approach with HER2 targeting in 18% of carcinomas
    • Epub 2012 Aug 18
    • Anglesio M, Kommoss S, Tolcher M, Clarke B, Galletta L, Porter H, et al. Molecular characterization of mucinous ovarian tumors supports a stratified treatment approach with HER2 targeting in 18% of carcinomas. J Pathol. 2012;229:111-20. Epub 2012 Aug 18.
    • (2012) J Pathol , vol.229 , pp. 111-120
    • Anglesio, M.1    Kommoss, S.2    Tolcher, M.3    Clarke, B.4    Galletta, L.5    Porter, H.6
  • 42
    • 81855201821 scopus 로고    scopus 로고
    • Dual-colour HER2/chromosome 17 chromogenic in situ hybridisation enables accurate assessment of HER2 genomic status in ovarian tumours
    • 21896578 Epub 2011 Sep 8
    • Yan B, Choo SN, Mulyadi P, Srivastava S, Ong CW, Yong KJ, et al. Dual-colour HER2/chromosome 17 chromogenic in situ hybridisation enables accurate assessment of HER2 genomic status in ovarian tumours. J Clin Pathol. 2011;64(12):1097-101. Epub 2011 Sep 8.
    • (2011) J Clin Pathol , vol.64 , Issue.12 , pp. 1097-1101
    • Yan, B.1    Choo, S.N.2    Mulyadi, P.3    Srivastava, S.4    Ong, C.W.5    Yong, K.J.6
  • 43
    • 84863599600 scopus 로고    scopus 로고
    • HER2 expression in ovarian carcinoma: Caution and complexity in biomarker analysis
    • 22412045 author reply 671-672. Epub 2012 Mar 14
    • McCaughan H, Um I, Langdon SP, Harrison DJ, Faratian D. HER2 expression in ovarian carcinoma: caution and complexity in biomarker analysis. J Clin Pathol. 2012;65(7):670-1; author reply 671-2. Epub 2012 Mar 14.
    • (2012) J Clin Pathol , vol.65 , Issue.7 , pp. 670-671
    • McCaughan, H.1    Um, I.2    Langdon, S.P.3    Harrison, D.J.4    Faratian, D.5
  • 44
  • 45
    • 84858407584 scopus 로고    scopus 로고
    • Heterogeneity mapping of protein expression in tumors using quantitative immunofluorescence
    • 22064683 Epub 2011 Nov 9
    • Faratian D, Christiansen J, Gustavson M, Jones C, Scott C, Um I, et al. Heterogeneity mapping of protein expression in tumors using quantitative immunofluorescence. J Vis Exp. 2011;56:e3334. Epub 2011 Nov 9.
    • (2011) J Vis Exp , vol.56 , pp. 3334
    • Faratian, D.1    Christiansen, J.2    Gustavson, M.3    Jones, C.4    Scott, C.5    Um, I.6
  • 46
    • 79952712084 scopus 로고    scopus 로고
    • Genomic analysis reveals the molecular heterogeneity of ovarian clear cell carcinomas
    • 21411445 1:CAS:528:DC%2BC3MXjtFChsbo%3D Epub 2011 Mar 18
    • Tan DS, Iravani M, McCluggage WG, Lambros MB, Milanezi F, Mackay A, et al. Genomic analysis reveals the molecular heterogeneity of ovarian clear cell carcinomas. Clin Cancer Res. 2011;17(6):1521-34. Epub 2011 Mar 18.
    • (2011) Clin Cancer Res , vol.17 , Issue.6 , pp. 1521-1534
    • Tan, D.S.1    Iravani, M.2    McCluggage, W.G.3    Lambros, M.B.4    Milanezi, F.5    MacKay, A.6
  • 47
    • 0036869728 scopus 로고    scopus 로고
    • HER2 is frequently over-expressed in ovarian clear cell adenocarcinoma: Possible novel treatment modality using recombinant monoclonal antibody against HER2, trastuzumab
    • Fujimura M, Katsumata N, Tsuda H, Uchi N, Miyazaki S, Hidaka T, et al. HER2 is frequently over-expressed in ovarian clear cell adenocarcinoma: possible novel treatment modality using recombinant monoclonal antibody against HER2, trastuzumab. Jpn J Cancer Res. 2002;93(11):1250-7. Epub 2002 Dec 4. (Pubitemid 36032989)
    • (2002) Japanese Journal of Cancer Research , vol.93 , Issue.11 , pp. 1250-1257
    • Fujimura, M.1    Katsumata, N.2    Tsuda, H.3    Uchi, N.4    Miyazaki, S.5    Hidaka, T.6    Sakai, M.7    Saito, S.8
  • 48
    • 67349129457 scopus 로고    scopus 로고
    • Status of HER1 and HER2 in peritoneal, ovarian and colorectal endometriosis and ovarian endometrioid adenocarcinoma
    • 1:CAS:528:DC%2BD1MXlt1SmtLk%3D Epub 2009 Mar 19
    • Uzan C, Darai E, Valent A, Graesslin O, Cortez A, Rouzier R, et al. Status of HER1 and HER2 in peritoneal, ovarian and colorectal endometriosis and ovarian endometrioid adenocarcinoma. Virchows Arch Int J Pathol. 2009;454(5):525-9. Epub 2009 Mar 19.
    • (2009) Virchows Arch Int J Pathol , vol.454 , Issue.5 , pp. 525-529
    • Uzan, C.1    Darai, E.2    Valent, A.3    Graesslin, O.4    Cortez, A.5    Rouzier, R.6
  • 49
    • 0028927113 scopus 로고
    • Overexpression of c-erbB-2 in epithelial ovarian cancer. Prognostic value and relationship with response to chemotherapy
    • 7697606 1:STN:280:DyaK2M3htFOiug%3D%3D Epub 1995 Apr 15
    • Felip E, Del Campo JM, Rubio D, Vidal MT, Colomer R, Bermejo B. Overexpression of c-erbB-2 in epithelial ovarian cancer. Prognostic value and relationship with response to chemotherapy. Cancer. 1995;75(8):2147-52. Epub 1995 Apr 15.
    • (1995) Cancer , vol.75 , Issue.8 , pp. 2147-2152
    • Felip, E.1    Del Campo, J.M.2    Rubio, D.3    Vidal, M.T.4    Colomer, R.5    Bermejo, B.6
  • 50
    • 7444228551 scopus 로고    scopus 로고
    • Analysis of HER-2/neu amplification in endometrial carcinoma by chromogenic in situ hybridization. Correlation with fluorescence in situ hybridization, HER-2/neu, p53 and Ki-67 protein expression, and outcome
    • 1:STN:280:DC%2BD2c3htlKksQ%3D%3D Epub 2004 Jan 31
    • Peiro G, Mayr D, Hillemanns P, Lohrs U, Diebold J. Analysis of HER-2/neu amplification in endometrial carcinoma by chromogenic in situ hybridization. Correlation with fluorescence in situ hybridization, HER-2/neu, p53 and Ki-67 protein expression, and outcome. Modern Pathol. 2004;17(3):227-87. Epub 2004 Jan 31.
    • (2004) Modern Pathol , vol.17 , Issue.3 , pp. 227-287
    • Peiro, G.1    Mayr, D.2    Hillemanns, P.3    Lohrs, U.4    Diebold, J.5
  • 51
    • 33744828734 scopus 로고    scopus 로고
    • HER-2 is an independent prognostic factor in endometrial cancer: Association with outcome in a large cohort of surgically staged patients
    • DOI 10.1200/JCO.2005.03.4827
    • Morrison C, Zanagnolo V, Ramirez N, Cohn DE, Kelbick N, Copeland L, et al. HER-2 is an independent prognostic factor in endometrial cancer: association with outcome in a large cohort of surgically staged patients. J Clin Oncol. 2006;24(15):2376-85. Epub 2006 May 20. (Pubitemid 46630670)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.15 , pp. 2376-2385
    • Morrison, C.1    Zanagnolo, V.2    Ramirez, N.3    Cohn, D.E.4    Kelbick, N.5    Copeland, L.6    Maxwell, L.G.7    Fowler, J.M.8
  • 52
    • 70749097152 scopus 로고    scopus 로고
    • Phase II trial of trastuzumab in women with advanced or recurrent, HER2-positive endometrial carcinoma: A Gynecologic Oncology Group study
    • 19840887 1:CAS:528:DC%2BD1MXhsFahsbbE Epub 2009 Oct 21
    • Fleming GF, Sill MW, Darcy KM, McMeekin DS, Thigpen JT, Adler LM, et al. Phase II trial of trastuzumab in women with advanced or recurrent, HER2-positive endometrial carcinoma: a Gynecologic Oncology Group study. Gynecol Oncol. 2010;116(1):15-20. Epub 2009 Oct 21.
    • (2010) Gynecol Oncol , vol.116 , Issue.1 , pp. 15-20
    • Fleming, G.F.1    Sill, M.W.2    Darcy, K.M.3    McMeekin, D.S.4    Thigpen, J.T.5    Adler, L.M.6
  • 53
    • 0029778221 scopus 로고    scopus 로고
    • Endometrial papillary serous carcinoma: Patterns of spread and treatment
    • DOI 10.1097/00003081-199609000-00016
    • Nicklin JL, Copeland LJ. Endometrial papillary serous carcinoma: patterns of spread and treatment. Clin Obstet Gynecol. 1996;39(3):686-95. Epub 1996 Sep 1. (Pubitemid 26321381)
    • (1996) Clinical Obstetrics and Gynecology , vol.39 , Issue.3 , pp. 686-695
    • Nicklin, J.L.1    Copeland, L.J.2
  • 56
    • 0020071243 scopus 로고
    • Uterine papillary serous carcinoma. A highly malignant form of endometrial adenocarcinoma
    • Hendrickson M, Ross J, Eifel P, Martinez A, Kempson R. Uterine papillary serous carcinoma: a highly malignant form of endometrial adenocarcinoma. Am J Surg Pathol. 1982;6(2):93-108. Epub 1982 Mar 1. (Pubitemid 12108965)
    • (1982) American Journal of Surgical Pathology , vol.6 , Issue.2 , pp. 93-108
    • Hendrickson, M.1    Ross, J.2    Martinez, A.3
  • 62
    • 0036261049 scopus 로고    scopus 로고
    • Malignant biphasic uterine tumours: Carcinosarcomas or metaplastic carcinomas?
    • McCluggage WG. Malignant biphasic uterine tumours: carcinosarcomas or metaplastic carcinomas? J Clin Pathol. 2002;55(5):321-5. Epub 2002 May 3. (Pubitemid 34494168)
    • (2002) Journal of Clinical Pathology , vol.55 , Issue.5 , pp. 321-325
    • McCluggage, W.G.1
  • 65
    • 29144507745 scopus 로고    scopus 로고
    • EGFR expression and HER2/neu overexpression/amplification in endometrial carcinosarcoma
    • DOI 10.1016/j.ygyno.2005.07.124, PII S0090825805006670
    • Livasy CA, Reading FC, Moore DT, Boggess JF, Lininger RA. EGFR expression and HER2/neu overexpression/amplification in endometrial carcinosarcoma. Gynecol Oncol. 2006;100(1):101-6. Epub 2005 Sep 15. (Pubitemid 41815057)
    • (2006) Gynecologic Oncology , vol.100 , Issue.1 , pp. 101-106
    • Livasy, C.A.1    Reading, F.C.2    Moore, D.T.3    Boggess, J.F.4    Lininger, R.A.5
  • 66
    • 0344668685 scopus 로고    scopus 로고
    • Different expression patterns of KIT, EGFR, and HER-2 (c-erbB-2) oncoproteins between epithelial and mesenchymal components in uterine carcinosarcoma
    • DOI 10.1111/j.1349-7006.2003.tb01389.x
    • Sawada M, Tsuda H, Kimura M, Okamoto S, Kita T, Kasamatsu T, et al. Different expression patterns of KIT, EGFR, and HER-2 (c-erbB-2) oncoproteins between epithelial and mesenchymal components in uterine carcinosarcoma. Cancer Sci. 2003;94(11):986-91. Epub 2003 Nov 13. (Pubitemid 37508982)
    • (2003) Cancer Science , vol.94 , Issue.11 , pp. 986-991
    • Sawada, M.1    Tsuda, H.2    Kimura, M.3    Okamoto, S.4    Kita, T.5    Kasamatsu, T.6    Yamada, T.7    Kikuchi, Y.8    Honjo, H.9    Matsubara, O.10
  • 67
    • 84862566462 scopus 로고    scopus 로고
    • HER2/neu as a potential target for immunotherapy in gynecologic carcinosarcomas
    • 22498937 1:CAS:528:DC%2BC38XptVGnsbs%3D Epub 2012 Apr 14
    • Guzzo F, Bellone S, Buza N, Hui P, Carrara L, Varughese J, et al. HER2/neu as a potential target for immunotherapy in gynecologic carcinosarcomas. Int J Gynecol Pathol. 2012;31(3):211-21. Epub 2012 Apr 14.
    • (2012) Int J Gynecol Pathol , vol.31 , Issue.3 , pp. 211-221
    • Guzzo, F.1    Bellone, S.2    Buza, N.3    Hui, P.4    Carrara, L.5    Varughese, J.6
  • 68
    • 0026741532 scopus 로고
    • Prognostic value of c-erbB-2 expression in uterine cervical carcinoma
    • 1355495 1:STN:280:DyaK38zovVCktA%3D%3D Epub 1992 Jul 1
    • Hale RJ, Buckley CH, Fox H, Williams J. Prognostic value of c-erbB-2 expression in uterine cervical carcinoma. J Clin Pathol. 1992;45(7):594-6. Epub 1992 Jul 1.
    • (1992) J Clin Pathol , vol.45 , Issue.7 , pp. 594-596
    • Hale, R.J.1    Buckley, C.H.2    Fox, H.3    Williams, J.4
  • 69
    • 0141869054 scopus 로고    scopus 로고
    • Selection of HER-2/neu-positive tumor cells in early stage cervical cancer: Implications for Herceptin-mediated therapy
    • DOI 10.1016/S0090-8258(03)00460-8
    • Bellone S, Palmieri M, Gokden M, Joshua J, Roman JJ, Pecorelli S, et al. Selection of HER-2/neu-positive tumor cells in early stage cervical cancer: implications for Herceptin-mediated therapy. Gynecol Oncol. 2003;91(1):231-40. Epub 2003 Oct 8. (Pubitemid 37188617)
    • (2003) Gynecologic Oncology , vol.91 , Issue.1 , pp. 231-240
    • Bellone, S.1    Palmieri, M.2    Gokden, M.3    Joshua, J.4    Roman, J.J.5    Pecorelli, S.6    Cannon, M.J.7    Santin, A.D.8
  • 70
    • 0025073536 scopus 로고
    • Expression of epidermal growth factor receptor and HER-2/neu in normal and neoplastic cervix, vulva, and vagina
    • Berchuck A, Rodriguez G, Kamel A, Soper JT, Clarke-Pearson DL, Bast RC Jr. Expression of epidermal growth factor receptor and HER-2/neu in normal and neoplastic cervix, vulva, and vagina. Obstet Gynecol. 1990;76(3 Pt 1):381-7. Epub 1990 Sep 11. (Pubitemid 20264521)
    • (1990) Obstetrics and Gynecology , vol.76 , Issue.3 , pp. 381-387
    • Berchuck, A.1    Rodriguez, G.2    Kamel, A.3    Soper, J.T.4    Clarke-Pearson, D.L.5    Bast Jr., R.C.6
  • 71
    • 0036677955 scopus 로고    scopus 로고
    • Paget's disease of the vulva
    • 12193912 discussion 283-284, Epub 2002 Aug 24
    • Tebes S, Cardosi R, Hoffman M. Paget's disease of the vulva. Am J Obstet Gynecol. 2002;187(2):281-3; discussion 283-4. Epub 2002 Aug 24.
    • (2002) Am J Obstet Gynecol , vol.187 , Issue.2 , pp. 281-283
    • Tebes, S.1    Cardosi, R.2    Hoffman, M.3
  • 72
    • 77953701654 scopus 로고    scopus 로고
    • HER-2/NEU overexpression in vulvar Paget disease: The Yale experience
    • 20418225 1:CAS:528:DC%2BC3cXovVGjsLc%3D Epub 2010 Apr 27
    • Richter CE, Hui P, Buza N, Silasi DA, Azodi M, Santin AD, et al. HER-2/NEU overexpression in vulvar Paget disease: the Yale experience. J Clin Pathol. 2010;63(6):544-7. Epub 2010 Apr 27.
    • (2010) J Clin Pathol , vol.63 , Issue.6 , pp. 544-547
    • Richter, C.E.1    Hui, P.2    Buza, N.3    Silasi, D.A.4    Azodi, M.5    Santin, A.D.6
  • 73
    • 33746604292 scopus 로고    scopus 로고
    • Predictive factors for response to docetaxel in human breast cancers
    • DOI 10.1111/j.1349-7006.2006.00265.x
    • Noguchi S. Predictive factors for response to docetaxel in human breast cancers. Cancer Sci. 2006;97(9):813-20. Epub 2006 Jun 30. (Pubitemid 44151259)
    • (2006) Cancer Science , vol.97 , Issue.9 , pp. 813-820
    • Noguchi, S.1
  • 74
    • 84866646922 scopus 로고    scopus 로고
    • Overexpression of class III beta tubulin and amplified HER2 gene predict good response to paclitaxel and trastuzumab therapy
    • 23028798 1:CAS:528:DC%2BC38XhsVaktr7M Epub 2012 Oct 3
    • Jung M, Koo JS, Moon YW, Park BW, Kim SI, Park S, et al. Overexpression of class III beta tubulin and amplified HER2 gene predict good response to paclitaxel and trastuzumab therapy. PloS One. 2012;7(9):e45127. Epub 2012 Oct 3.
    • (2012) PloS One , vol.7 , Issue.9 , pp. 45127
    • Jung, M.1    Koo, J.S.2    Moon, Y.W.3    Park, B.W.4    Kim, S.I.5    Park, S.6
  • 75
    • 51649098179 scopus 로고    scopus 로고
    • Prognostic value of hormonal receptors, p53, ki67 and HER2/neu expression in epithelial ovarian carcinoma
    • 18558584 1:CAS:528:DC%2BD1cXpt1Gks7s%3D Epub 2008 Jun 19
    • Garcia-Velasco A, Mendiola C, Sanchez-Munoz A, Ballestin C, Colomer R, Cortes-Funes H. Prognostic value of hormonal receptors, p53, ki67 and HER2/neu expression in epithelial ovarian carcinoma. Clin Transl Oncol. 2008;10(6):367-71. Epub 2008 Jun 19.
    • (2008) Clin Transl Oncol , vol.10 , Issue.6 , pp. 367-371
    • Garcia-Velasco, A.1    Mendiola, C.2    Sanchez-Munoz, A.3    Ballestin, C.4    Colomer, R.5    Cortes-Funes, H.6
  • 76
    • 77955177246 scopus 로고    scopus 로고
    • Immunohistochemical study of HER2 and TUBB3 proteins in extramammary Paget disease
    • 20534991 Epub 2010 Jun 11
    • Miyamoto A, Akasaka K, Oikawa H, Akasaka T, Masuda T, Maesawa C. Immunohistochemical study of HER2 and TUBB3 proteins in extramammary Paget disease. Am J Dermatopathol. 2010;32(6):578-85. Epub 2010 Jun 11.
    • (2010) Am J Dermatopathol , vol.32 , Issue.6 , pp. 578-585
    • Miyamoto, A.1    Akasaka, K.2    Oikawa, H.3    Akasaka, T.4    Masuda, T.5    Maesawa, C.6
  • 77
    • 0034076307 scopus 로고    scopus 로고
    • Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets
    • DOI 10.1038/74704
    • Clynes RA, Towers TL, Presta LG, Ravetch JV. Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets. Nat Med. 2000;6(4):443-6. Epub 2000 Mar 31. (Pubitemid 30208162)
    • (2000) Nature Medicine , vol.6 , Issue.4 , pp. 443-446
    • Clynes, R.A.1    Towers, T.L.2    Presta, L.G.3    Ravetch, J.V.4
  • 78
    • 2542460202 scopus 로고    scopus 로고
    • 2 fragments of a mixture of three monoclonal anti-Her-2 antibodies
    • DOI 10.1158/1078-0432.CCR-03-0549
    • Spiridon CI, Guinn S, Vitetta ES. A comparison of the in vitro and in vivo activities of IgG and F(ab')2 fragments of a mixture of three monoclonal anti-Her-2 antibodies. Clin Cancer Res. 2004;10(10):3542-51. Epub 2004 May 27. (Pubitemid 38685465)
    • (2004) Clinical Cancer Research , vol.10 , Issue.10 , pp. 3542-3551
    • Spiridon, C.I.1    Guinn, S.2    Vitetta, E.S.3
  • 79
    • 79957874790 scopus 로고    scopus 로고
    • FcgammaR2A and 3A polymorphisms predict clinical outcome of trastuzumab in both neoadjuvant and metastatic settings in patients with HER2-positive breast cancer
    • 21109570 1:STN:280:DC%2BC3MrkvFOntQ%3D%3D Epub 2010 Nov 27
    • Tamura K, Shimizu C, Hojo T, Akashi-Tanaka S, Kinoshita T, Yonemori K, et al. FcgammaR2A and 3A polymorphisms predict clinical outcome of trastuzumab in both neoadjuvant and metastatic settings in patients with HER2-positive breast cancer. Ann Oncol. 2011;22(6):1302-7. Epub 2010 Nov 27.
    • (2011) Ann Oncol , vol.22 , Issue.6 , pp. 1302-1307
    • Tamura, K.1    Shimizu, C.2    Hojo, T.3    Akashi-Tanaka, S.4    Kinoshita, T.5    Yonemori, K.6
  • 80
    • 42949157368 scopus 로고    scopus 로고
    • Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer
    • 18347005 1:CAS:528:DC%2BD1cXmsFemsLg%3D Epub 2008 Mar 19
    • Musolino A, Naldi N, Bortesi B, Pezzuolo D, Capelletti M, Missale G, et al. Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer. J Clin Oncol. 2008;26(11):1789-96. Epub 2008 Mar 19.
    • (2008) J Clin Oncol , vol.26 , Issue.11 , pp. 1789-1796
    • Musolino, A.1    Naldi, N.2    Bortesi, B.3    Pezzuolo, D.4    Capelletti, M.5    Missale, G.6
  • 81
    • 4444372733 scopus 로고    scopus 로고
    • Pilot study of the mechanism of action of preoperative trastuzumab in patients with primary operable breast tumors overexpressing HER2
    • Epub 2008 Mar 19
    • Gennari R, Menard S, Fagnoni F, Ponchio L, Scelsi M, Tagliabue E, et al. Pilot study of the mechanism of action of preoperative trastuzumab in patients with primary operable breast tumors overexpressing HER2. Clin Cancer Res. 2004;10(17):5650.x-5.x. Epub 2008 Mar 19.
    • (2004) Clin Cancer Res , vol.10 , Issue.17
    • Gennari, R.1    Menard, S.2    Fagnoni, F.3    Ponchio, L.4    Scelsi, M.5    Tagliabue, E.6
  • 84
    • 74249095141 scopus 로고    scopus 로고
    • In vitro activity of pertuzumab in combination with trastuzumab in uterine serous papillary adenocarcinoma
    • 19920829 1:CAS:528:DC%2BC3cXhtFOrtg%3D%3D Epub 2009 Nov 19
    • El-Sahwi K, Bellone S, Cocco E, Cargnelutti M, Casagrande F, Bellone M, et al. In vitro activity of pertuzumab in combination with trastuzumab in uterine serous papillary adenocarcinoma. Br J Cancer. 2010;102(1):134-43. Epub 2009 Nov 19.
    • (2010) Br J Cancer , vol.102 , Issue.1 , pp. 134-143
    • El-Sahwi, K.1    Bellone, S.2    Cocco, E.3    Cargnelutti, M.4    Casagrande, F.5    Bellone, M.6
  • 86
    • 33749144509 scopus 로고    scopus 로고
    • HER-2/neu overexpression in uterine papillary serous cancers and its possible therapeutic implications
    • DOI 10.1111/j.1525-1438.2006.00664.x
    • Villella JA, Cohen S, Smith DH, Hibshoosh H, Hershman D. HER-2/neu overexpression in uterine papillary serous cancers and its possible therapeutic implications. Int J Gynecol Cancer. 2006;16(5):1897-902. Epub 2006 Oct 3. (Pubitemid 44470053)
    • (2006) International Journal of Gynecological Cancer , vol.16 , Issue.5 , pp. 1897-1902
    • Villella, J.A.1    Cohen, S.2    Smith, D.H.3    Hibshoosh, H.4    Hershman, D.5
  • 87
    • 46749152126 scopus 로고    scopus 로고
    • Trastuzumab treatment in patients with advanced or recurrent endometrial carcinoma overexpressing HER2/neu
    • 18555254 1:CAS:528:DC%2BD1cXosVyiu7Y%3D Epub 2008 Jun 17
    • Santin AD, Bellone S, Roman JJ, McKenney JK, Pecorelli S. Trastuzumab treatment in patients with advanced or recurrent endometrial carcinoma overexpressing HER2/neu. Int J Gynaecol Obstet. 2008;102(2):128-31. Epub 2008 Jun 17.
    • (2008) Int J Gynaecol Obstet , vol.102 , Issue.2 , pp. 128-131
    • Santin, A.D.1    Bellone, S.2    Roman, J.J.3    McKenney, J.K.4    Pecorelli, S.5
  • 89
    • 33846818624 scopus 로고    scopus 로고
    • Sensitivity to pertuzumab (2C4) in ovarian cancer models: Cross-talk with estrogen receptor signaling
    • DOI 10.1158/1535-7163.MCT-06-0401
    • Mullen P, Cameron DA, Hasmann M, Smyth JF, Langdon SP. Sensitivity to pertuzumab (2C4) in ovarian cancer models: cross-talk with estrogen receptor signaling. Mol Cancer Ther. 2007;6(1):93-100. Epub 2007 Jan 24. (Pubitemid 46206671)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.1 , pp. 93-100
    • Mullen, P.1    Cameron, D.A.2    Hasmann, M.3    Smyth, J.F.4    Langdon, S.P.5
  • 90
    • 19044380618 scopus 로고    scopus 로고
    • Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth
    • Epub 2007 Jan 24
    • Agus DB, Akita RW, Fox WD, Lewis GD, Higgins B, Pisacane PI, et al. Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth. Cancer cell. 2002;2(2):127.x-37.x. Epub 2007 Jan 24.
    • (2002) Cancer Cell , vol.2 , Issue.2
    • Agus, D.B.1    Akita, R.W.2    Fox, W.D.3    Lewis, G.D.4    Higgins, B.5    Pisacane, P.I.6
  • 91
    • 1942441770 scopus 로고    scopus 로고
    • Blockade of Epidermal Growth Factor- or Heregulin-Dependent ErbB2 Activation with the Anti-ErbB2 Monoclonal Antibody 2C4 Has Divergent Downstream Signaling and Growth Effects
    • DOI 10.1158/0008-5472.CAN-03-3106
    • Jackson JG, St Clair P, Sliwkowski MX, Brattain MG. Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects. Cancer Res. 2004;64(7):2601-9. Epub 2004 Apr 3. (Pubitemid 38523918)
    • (2004) Cancer Research , vol.64 , Issue.7 , pp. 2601-2609
    • Jackson, J.G.1    St. Clair, P.2    Sliwkowski, M.X.3    Brattain, M.G.4
  • 92
    • 1942474587 scopus 로고    scopus 로고
    • The HER-2-Targeting Antibodies Trastuzumab and Pertuzumab Synergistically Inhibit the Survival of Breast Cancer Cells
    • DOI 10.1158/0008-5472.CAN-03-3856
    • Nahta R, Hung MC, Esteva FJ. The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells. Cancer Res. 2004;64(7):2343-6. Epub 2004 Apr 3. (Pubitemid 38523885)
    • (2004) Cancer Research , vol.64 , Issue.7 , pp. 2343-2346
    • Nahta, R.1    Hung, M.-C.2    Esteva, F.J.3
  • 93
    • 29144434036 scopus 로고    scopus 로고
    • 2C4, a monoclonal antibody against HER2, disrupts the HER kinase signaling pathway and inhibits ovarian carcinoma cell growth
    • DOI 10.1002/cncr.21533
    • Takai N, Jain A, Kawamata N, Popoviciu LM, Said JW, Whittaker S, et al. 2C4, a monoclonal antibody against HER2, disrupts the HER kinase signaling pathway and inhibits ovarian carcinoma cell growth. Cancer. 2005;104(12):2701-8. Epub 2005 Nov 3. (Pubitemid 41798280)
    • (2005) Cancer , vol.104 , Issue.12 , pp. 2701-2708
    • Takai, N.1    Jain, A.2    Kawamata, N.3    Popoviciu, L.M.4    Said, J.W.5    Whittaker, S.6    Miyakawa, I.7    Agus, D.B.8    Koeffler, H.P.9
  • 94
    • 84868520609 scopus 로고    scopus 로고
    • Trastuzumab emtansine for HER2-positive advanced breast cancer
    • 23020162 1:CAS:528:DC%2BC38Xhs1ekt73M Epub 2012 Oct 2
    • Verma S, Miles D, Gianni L, Krop IE, Welslau M, Baselga J, et al. Trastuzumab emtansine for HER2-positive advanced breast cancer. N Engl J Med. 2012;367:1783-91. Epub 2012 Oct 2.
    • (2012) N Engl J Med , vol.367 , pp. 1783-1791
    • Verma, S.1    Miles, D.2    Gianni, L.3    Krop, I.E.4    Welslau, M.5    Baselga, J.6
  • 95
    • 79955475247 scopus 로고    scopus 로고
    • Trastuzumab-DM1 is highly effective in preclinical models of HER2-positive gastric cancer
    • Epub 2012 Oct 2
    • Barok M, Tanner M, Koninki K, Isola J. Trastuzumab-DM1 is highly effective in preclinical models of HER2-positive gastric cancer. Cancer Lett. 2011;306(2):171.x-9.x. Epub 2012 Oct 2.
    • (2011) Cancer Lett , vol.306 , Issue.2
    • Barok, M.1    Tanner, M.2    Koninki, K.3    Isola, J.4
  • 96
    • 77949429770 scopus 로고    scopus 로고
    • Ovarian cancer immunotherapy: Opportunities, progresses and challenges
    • 20146807 Epub 2010 Feb 12
    • Liu B, Nash J, Runowicz C, Swede H, Stevens R, Li Z. Ovarian cancer immunotherapy: opportunities, progresses and challenges. J Hematol Oncol. 2010;3:7. Epub 2010 Feb 12.
    • (2010) J Hematol Oncol , vol.3 , pp. 7
    • Liu, B.1    Nash, J.2    Runowicz, C.3    Swede, H.4    Stevens, R.5    Li, Z.6
  • 97
    • 77950189167 scopus 로고    scopus 로고
    • Ovarian cancer creates a suppressive microenvironment to escape immune elimination
    • Epub 2010 Feb 12
    • Yigit R, Massuger LF, Figdor CG, Torensma R. Ovarian cancer creates a suppressive microenvironment to escape immune elimination. Gynecol Oncol. 2010;117(2):366.x-72.x. Epub 2010 Feb 12.
    • (2010) Gynecol Oncol , vol.117 , Issue.2
    • Yigit, R.1    Massuger, L.F.2    Figdor, C.G.3    Torensma, R.4
  • 98
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • DOI 10.1016/j.immuni.2004.07.017, PII S1074761304002092
    • Dunn GP, Old LJ, Schreiber RD. The immunobiology of cancer immunosurveillance and immunoediting. Immunity. 2004;21(2):137-48. Epub 2004 Aug 17. (Pubitemid 39094044)
    • (2004) Immunity , vol.21 , Issue.2 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 99
    • 67650491811 scopus 로고    scopus 로고
    • Treatment of metastatic melanoma: An overview
    • Epub 2009 Jun 24
    • Bhatia S, Tykodi SS, Thompson JA. Treatment of metastatic melanoma: an overview. Oncology (Williston Park). 2009;23(6):488-96. Epub 2009 Jun 24.
    • (2009) Oncology (Williston Park) , vol.23 , Issue.6 , pp. 488-496
    • Bhatia, S.1    Tykodi, S.S.2    Thompson, J.A.3
  • 100
    • 79957602397 scopus 로고    scopus 로고
    • Immunology. Regulatory T cells get their chance to shine
    • 21617049 1:CAS:528:DC%2BC3MXns1Gguro%3D Epub 2011 May 28
    • Leslie M. Immunology. Regulatory T cells get their chance to shine. Science. 2011;332(6033):1020-1. Epub 2011 May 28.
    • (2011) Science , vol.332 , Issue.6033 , pp. 1020-1021
    • Leslie, M.1
  • 101
    • 84860721657 scopus 로고    scopus 로고
    • Selectively expanding subsets of T cells in mice by injection of interleukin-2/antibody complexes: Implications for transplantation tolerance
    • 1:CAS:528:DC%2BC38Xmslyisb0%3D Epub 2012 May 9
    • Boyman O, Krieg C, Letourneau S, Webster K, Surh CD, Sprent J. Selectively expanding subsets of T cells in mice by injection of interleukin-2/antibody complexes: implications for transplantation tolerance. Transpl Proc. 2012;44(4):1032-4. Epub 2012 May 9.
    • (2012) Transpl Proc , vol.44 , Issue.4 , pp. 1032-1034
    • Boyman, O.1    Krieg, C.2    Letourneau, S.3    Webster, K.4    Surh, C.D.5    Sprent, J.6
  • 102
    • 84863230537 scopus 로고    scopus 로고
    • Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer
    • 22326955 1:CAS:528:DC%2BC38XjsV2mtrw%3D Epub 2012 Feb 14
    • Kohrt HE, Houot R, Weiskopf K, Goldstein MJ, Scheeren F, Czerwinski D, et al. Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer. J Clin Invest. 2012;122(3):1066-75. Epub 2012 Feb 14.
    • (2012) J Clin Invest , vol.122 , Issue.3 , pp. 1066-1075
    • Kohrt, H.E.1    Houot, R.2    Weiskopf, K.3    Goldstein, M.J.4    Scheeren, F.5    Czerwinski, D.6
  • 103
    • 0035524114 scopus 로고    scopus 로고
    • Improving the efficacy of antibody-based cancer therapies
    • Carter P. Improving the efficacy of antibody-based cancer therapies. Nat Rev Cancer. 2001;1(2):118-29. Epub 2002 Mar 22. (Pubitemid 33741887)
    • (2001) Nature Reviews Cancer , vol.1 , Issue.2 , pp. 118-129
    • Carter, P.1
  • 104
    • 0036226284 scopus 로고    scopus 로고
    • The inhibitory effect of CD46, CD55, and CD59 on complement activation after immunotherapeutic treatment of cervical carcinoma cells with monoclonal antibodies or bispecific monoclonal antibodies
    • Gelderman KA, Blok VT, Fleuren GJ, Gorter A. The inhibitory effect of CD46, CD55, and CD59 on complement activation after immunotherapeutic treatment of cervical carcinoma cells with monoclonal antibodies or bispecific monoclonal antibodies. Lab Invest. 2002;82(4):483-93. Epub 2002 Apr 16. (Pubitemid 34311120)
    • (2002) Laboratory Investigation , vol.82 , Issue.4 , pp. 483-493
    • Gelderman, K.A.1    Blok, V.T.2    Fleuren, G.J.3    Gorter, A.4
  • 105
    • 0029898496 scopus 로고    scopus 로고
    • Expression of CD46, CD55, and CD59 on renal tumor cell lines and their role in preventing complement-mediated tumor cell lysis
    • Gorter A, Blok VT, Haasnoot WH, Ensink NG, Daha, Fleuren GJ. Expression of CD46, CD55, and CD59 on renal tumor cell lines and their role in preventing complement-mediated tumor cell lysis. Lab Invest. 1996;74(6):1039-49. Epub 1996 Jun 1. (Pubitemid 26182416)
    • (1996) Laboratory Investigation , vol.74 , Issue.6 , pp. 1039-1049
    • Gorter, A.1    Blok, V.T.2    Haasnoot, W.H.B.3    Ensink, N.G.4    Daha, M.R.5    Fleuren, G.J.6
  • 106
    • 0029900739 scopus 로고    scopus 로고
    • Human carcinomas variably express the complement inhibitory proteins CD46 (membrane cofactor protein), CD55 (decay-accelerating factor), and CD59 (protectin)
    • Niehans GA, Cherwitz DL, Staley NA, Knapp DJ, Dalmasso AP. Human carcinomas variably express the complement inhibitory proteins CD46 (membrane cofactor protein), CD55 (decay-accelerating factor), and CD59 (protectin). Am J Pathol. 1996;149(1):129-42. Epub 1996 Jul 1. (Pubitemid 26230985)
    • (1996) American Journal of Pathology , vol.149 , Issue.1 , pp. 129-142
    • Niehans, G.A.1    Cherwitz, D.L.2    Staley, N.A.3    Knapp, D.J.4    Dalmasso, A.P.5
  • 107
    • 28844480528 scopus 로고    scopus 로고
    • Inhibiting complement regulators in cancer immunotherapy with bispecific mAbs
    • DOI 10.1517/14712598.5.12.1593
    • Gelderman KA, Lam S, Gorter A. Inhibiting complement regulators in cancer immunotherapy with bispecific mAbs. Expert Opin Biol Ther. 2005;5(12):1593-601. Epub 2005 Dec 2. (Pubitemid 41771850)
    • (2005) Expert Opinion on Biological Therapy , vol.5 , Issue.12 , pp. 1593-1601
    • Gelderman, K.A.1    Lam, S.2    Gorter, A.3
  • 108
    • 84860235422 scopus 로고    scopus 로고
    • Downregulation of membrane complement inhibitors CD55 and CD59 by siRNA sensitises uterine serous carcinoma overexpressing Her2/neu to complement and antibody-dependent cell cytotoxicity in vitro: Implications for trastuzumab-based immunotherapy
    • 22531721 1:CAS:528:DC%2BC38Xmt1Ghu78%3D Epub 2012 Apr 26
    • Bellone S, Roque D, Cocco E, Gasparrini S, Bortolomai I, Buza N, et al. Downregulation of membrane complement inhibitors CD55 and CD59 by siRNA sensitises uterine serous carcinoma overexpressing Her2/neu to complement and antibody-dependent cell cytotoxicity in vitro: implications for trastuzumab-based immunotherapy. Br J Cancer. 2012;106(9):1543-50. Epub 2012 Apr 26.
    • (2012) Br J Cancer , vol.106 , Issue.9 , pp. 1543-1550
    • Bellone, S.1    Roque, D.2    Cocco, E.3    Gasparrini, S.4    Bortolomai, I.5    Buza, N.6
  • 109
    • 77950371095 scopus 로고    scopus 로고
    • Implication of RICTOR in the mTOR inhibitor-mediated induction of insulin-like growth factor-I receptor (IGF-IR) and human epidermal growth factor receptor-2 (Her2) expression in gastrointestinal cancer cells
    • 1:CAS:528:DC%2BC3cXjt1Glu7o%3D Epub 2010 Feb 2
    • Lang SA, Hackl C, Moser C, Fichtner-Feigl S, Koehl GE, Schlitt HJ, et al. Implication of RICTOR in the mTOR inhibitor-mediated induction of insulin-like growth factor-I receptor (IGF-IR) and human epidermal growth factor receptor-2 (Her2) expression in gastrointestinal cancer cells. Biochimi Biophys Acta. 2010;1803(4):435-42. Epub 2010 Feb 2.
    • (2010) Biochimi Biophys Acta , vol.1803 , Issue.4 , pp. 435-442
    • Lang, S.A.1    Hackl, C.2    Moser, C.3    Fichtner-Feigl, S.4    Koehl, G.E.5    Schlitt, H.J.6
  • 110
    • 80051751593 scopus 로고    scopus 로고
    • Phase I/II study of trastuzumab in combination with everolimus (RAD001) in patients with HER2-overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy
    • 21730275 1:CAS:528:DC%2BC3MXhtFyqu7nK Epub 2011 Jul 7
    • Morrow PK, Wulf GM, Ensor J, Booser DJ, Moore JA, Flores PR, et al. Phase I/II study of trastuzumab in combination with everolimus (RAD001) in patients with HER2-overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy. J Clin Oncol. 2011;29(23):3126-32. Epub 2011 Jul 7.
    • (2011) J Clin Oncol , vol.29 , Issue.23 , pp. 3126-3132
    • Morrow, P.K.1    Wulf, G.M.2    Ensor, J.3    Booser, D.J.4    Moore, J.A.5    Flores, P.R.6
  • 111
    • 78650984926 scopus 로고    scopus 로고
    • Phase i study of everolimus plus weekly paclitaxel and trastuzumab in patients with metastatic breast cancer pretreated with trastuzumab
    • 20975068 1:CAS:528:DC%2BC3MXltlKnsA%3D%3D Epub 2010 Oct 27
    • Andre F, Campone M, O'Regan R, Manlius C, Massacesi C, Sahmoud T, et al. Phase I study of everolimus plus weekly paclitaxel and trastuzumab in patients with metastatic breast cancer pretreated with trastuzumab. J Clin Oncol. 2010;28(34):5110-5. Epub 2010 Oct 27.
    • (2010) J Clin Oncol , vol.28 , Issue.34 , pp. 5110-5115
    • Andre, F.1    Campone, M.2    O'Regan, R.3    Manlius, C.4    Massacesi, C.5    Sahmoud, T.6
  • 112
    • 55949117201 scopus 로고    scopus 로고
    • The growth inhibitory effect of lapatinib, a dual inhibitor of EGFR and HER2 tyrosine kinase, in gastric cancer cell lines
    • 18774637 1:CAS:528:DC%2BD1cXhtlyhtrzE Epub 2008 Sep 9
    • Kim JW, Kim HP, Im SA, Kang S, Hur HS, Yoon YK, et al. The growth inhibitory effect of lapatinib, a dual inhibitor of EGFR and HER2 tyrosine kinase, in gastric cancer cell lines. Cancer Lett. 2008;272(2):296-306. Epub 2008 Sep 9.
    • (2008) Cancer Lett , vol.272 , Issue.2 , pp. 296-306
    • Kim, J.W.1    Kim, H.P.2    Im, S.A.3    Kang, S.4    Hur, H.S.5    Yoon, Y.K.6
  • 113
    • 34548071359 scopus 로고    scopus 로고
    • Human breast cancer cells selected for resistance to trastuzumab in vivo overexpress epidermal growth factor receptor and ErbB ligands and remain dependent on the ErbB receptor network
    • DOI 10.1158/1078-0432.CCR-07-0701
    • Ritter CA, Perez-Torres M, Rinehart C, Guix M, Dugger T, Engelman JA, et al. Human breast cancer cells selected for resistance to trastuzumab in vivo overexpress epidermal growth factor receptor and ErbB ligands and remain dependent on the ErbB receptor network. Clin Cancer Res. 2007;13(16):4909-19. Epub 2007 Aug 19. (Pubitemid 47294799)
    • (2007) Clinical Cancer Research , vol.13 , Issue.16 , pp. 4909-4919
    • Ritter, C.A.1    Perez-Torres, M.2    Rinehart, C.3    Guix, M.4    Dugger, T.5    Engelman, J.A.6    Arteaga, C.L.7
  • 114
    • 34247588567 scopus 로고    scopus 로고
    • Expression of p95HER2, a truncated form of the HER2 receptor, and response to Anti-HER2 therapies in breast cancer
    • DOI 10.1093/jnci/djk134
    • Scaltriti M, Rojo F, Ocana A, Anido J, Guzman M, Cortes J, et al. Expression of p95HER2, a truncated form of the HER2 receptor, and response to anti-HER2 therapies in breast cancer. J Natl Cancer Inst. 2007;99(8):628-38. Epub 2007 Apr 19. (Pubitemid 47073544)
    • (2007) Journal of the National Cancer Institute , vol.99 , Issue.8 , pp. 628-638
    • Scaltriti, M.1    Rojo, F.2    Ocana, A.3    Anido, J.4    Guzman, M.5    Cortes, J.6    Di Cosimo, S.7
  • 115
    • 84858671737 scopus 로고    scopus 로고
    • EGFR/HER-targeted therapeutics in ovarian cancer
    • 1:CAS:528:DC%2BC38XktVajsLw%3D Epub 2012 Mar 16
    • Wilken JA, Badri T, Cross S, Raji R, Santin AD, Schwartz P, et al. EGFR/HER-targeted therapeutics in ovarian cancer. Futur Med Chem. 2012;4(4):447-69. Epub 2012 Mar 16.
    • (2012) Futur Med Chem , vol.4 , Issue.4 , pp. 447-469
    • Wilken, J.A.1    Badri, T.2    Cross, S.3    Raji, R.4    Santin, A.D.5    Schwartz, P.6
  • 116
    • 0035989680 scopus 로고    scopus 로고
    • HSP90 as a new therapeutic target for cancer therapy: The story unfolds
    • DOI 10.1517/14712598.2.1.3
    • Maloney A, Workman P. HSP90 as a new therapeutic target for cancer therapy: the story unfolds. Expert Opin Biol Ther. 2002;2(1):3-24. Epub 2002 Jan 5. (Pubitemid 34462457)
    • (2002) Expert Opinion on Biological Therapy , vol.2 , Issue.1 , pp. 3-24
    • Maloney, A.1    Workman, P.2
  • 117
    • 34248187981 scopus 로고    scopus 로고
    • Heat shock protein 90: The cancer chaperone
    • DOI 10.1007/s12038-007-0051-y
    • Neckers L. Heat shock protein 90: the cancer chaperone. J Biosci. 2007;32(3):517-30. Epub 2007 May 31. (Pubitemid 46708702)
    • (2007) Journal of Biosciences , vol.32 , Issue.3 , pp. 517-530
    • Neckers, L.1
  • 118
    • 0035300564 scopus 로고    scopus 로고
    • Inhibition of heat shock protein 90 function by ansamycins causes the morphological and functional differentiation of breast cancer cells
    • Munster PN, Srethapakdi M, Moasser MM, Rosen N. Inhibition of heat shock protein 90 function by ansamycins causes the morphological and functional differentiation of breast cancer cells. Cancer Res. 2001;61(7):2945-52. Epub 2001 Apr 18. (Pubitemid 32691939)
    • (2001) Cancer Research , vol.61 , Issue.7 , pp. 2945-2952
    • Munster, P.N.1    Srethapakdi, M.2    Moasser, M.M.3    Rosen, N.4
  • 119
    • 0036606332 scopus 로고    scopus 로고
    • Degradation of HER2 by ansamycins induces growth arrest and apoptosis in cells with HER2 overexpression via a HER3, phosphatidylinositol 3′-kinase-AKT-dependent pathway
    • Munster PN, Marchion DC, Basso AD, Rosen N. Degradation of HER2 by ansamycins induces growth arrest and apoptosis in cells with HER2 overexpression via a HER3, phosphatidylinositol 3′-kinase-AKT-dependent pathway. Cancer Res. 2002;62(11):3132-7. Epub 2002 May 31. (Pubitemid 34602405)
    • (2002) Cancer Research , vol.62 , Issue.11 , pp. 3132-3137
    • Munster, P.N.1    Marchion, D.C.2    Basso, A.D.3    Rosen, N.4
  • 120
    • 79851487744 scopus 로고    scopus 로고
    • Pretargeted 177Lu radioimmunotherapy of carcinoembryonic antigen-expressing human colonic tumors in mice
    • 21051650 Epub 2010 Nov 6
    • Schoffelen R, van der Graaf WT, Franssen G, Sharkey RM, Goldenberg DM, McBride WJ, et al. Pretargeted 177Lu radioimmunotherapy of carcinoembryonic antigen-expressing human colonic tumors in mice. J Nucl Med. 2010;51(11):1780-7. Epub 2010 Nov 6.
    • (2010) J Nucl Med , vol.51 , Issue.11 , pp. 1780-1787
    • Schoffelen, R.1    Van Der Graaf, W.T.2    Franssen, G.3    Sharkey, R.M.4    Goldenberg, D.M.5    McBride, W.J.6
  • 121
    • 84881186900 scopus 로고    scopus 로고
    • Phase 1 radioimmunotherapy study with lutetium 177-labeled anti-carbonic anhydrase IX monoclonal antibody girentuximab in patients with advanced renal cell carcinoma
    • Epub 2012 Sep 18.
    • Stillebroer AB, Boerman OC, Desar IM, Boers-Sonderen MJ, van Herpen CM, Langenhuijsen JF, et al. Phase 1 radioimmunotherapy study with lutetium 177-labeled anti-carbonic anhydrase IX monoclonal antibody girentuximab in patients with advanced renal cell carcinoma. Eur Urol. 2012. Epub 2012 Sep 18.
    • (2012) Eur Urol
    • Stillebroer, A.B.1    Boerman, O.C.2    Desar, I.M.3    Boers-Sonderen, M.J.4    Van Herpen, C.M.5    Langenhuijsen, J.F.6
  • 122
    • 79952017967 scopus 로고    scopus 로고
    • In vivo testing of 177Lu-labelled anti-PSMA antibody as a new radioimmunotherapeutic agent against prostate cancer
    • 21282735 1:CAS:528:DC%2BC3MXivVSmtbo%3D Epub 2011 Feb 2
    • Behe M, Alt K, Deininger F, Buhler P, Wetterauer U, Weber WA, et al. In vivo testing of 177Lu-labelled anti-PSMA antibody as a new radioimmunotherapeutic agent against prostate cancer. In Vivo. 2011;25(1):55-9. Epub 2011 Feb 2.
    • (2011) Vivo , vol.25 , Issue.1 , pp. 55-59
    • Behe, M.1    Alt, K.2    Deininger, F.3    Buhler, P.4    Wetterauer, U.5    Weber, W.A.6
  • 123
    • 84864531160 scopus 로고    scopus 로고
    • Fractionated therapy of HER2-expressing breast and ovarian cancer xenografts in mice with targeted alpha emitting 227Th-DOTA-p-benzyl-trastuzumab
    • 22879947 1:CAS:528:DC%2BC38XhtFOls7fL Epub 2012 Aug 11
    • Heyerdahl H, Abbas N, Brevik EM, Mollatt C, Dahle J. Fractionated therapy of HER2-expressing breast and ovarian cancer xenografts in mice with targeted alpha emitting 227Th-DOTA-p-benzyl-trastuzumab. PloS One. 2012;7(8):e42345. Epub 2012 Aug 11.
    • (2012) PloS One , vol.7 , Issue.8 , pp. 42345
    • Heyerdahl, H.1    Abbas, N.2    Brevik, E.M.3    Mollatt, C.4    Dahle, J.5
  • 124
    • 84855942409 scopus 로고    scopus 로고
    • Pre-clinical assessment of Lu-labeled trastuzumab targeting HER2 for treatment and management of cancer patients with disseminated intraperitoneal disease
    • Epub 2012 Jan 10
    • Ray GL, Baidoo KE, Keller LM, Albert PS, Brechbiel MW, Milenic DE. Pre-clinical assessment of Lu-labeled trastuzumab targeting HER2 for treatment and management of cancer patients with disseminated intraperitoneal disease. Pharmaceuticals (Basel). 2011;5(1):1-15. Epub 2012 Jan 10.
    • (2011) Pharmaceuticals (Basel) , vol.5 , Issue.1 , pp. 1-15
    • Ray, G.L.1    Baidoo, K.E.2    Keller, L.M.3    Albert, P.S.4    Brechbiel, M.W.5    Milenic, D.E.6
  • 126
    • 84862495613 scopus 로고    scopus 로고
    • Phase I/II randomized trial of dendritic cell vaccination with or without cyclophosphamide for consolidation therapy of advanced ovarian cancer in first or second remission
    • 22021066 1:CAS:528:DC%2BC38XmtlCqsLg%3D Epub 2011 Oct 25
    • Chu CS, Boyer J, Schullery DS, Gimotty PA, Gamerman V, Bender J, et al. Phase I/II randomized trial of dendritic cell vaccination with or without cyclophosphamide for consolidation therapy of advanced ovarian cancer in first or second remission. Cancer Immunol Immunother. 2012;61(5):629-41. Epub 2011 Oct 25.
    • (2012) Cancer Immunol Immunother , vol.61 , Issue.5 , pp. 629-641
    • Chu, C.S.1    Boyer, J.2    Schullery, D.S.3    Gimotty, P.A.4    Gamerman, V.5    Bender, J.6
  • 127
    • 0020047427 scopus 로고
    • Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells
    • DOI 10.1084/jem.155.4.1063
    • North RJ. Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells. J Exp Med. 1982;155(4):1063-74. Epub 1982 Apr 1. (Pubitemid 12142723)
    • (1982) Journal of Experimental Medicine , vol.155 , Issue.4 , pp. 1063-1074
    • North, R.J.1
  • 129
    • 84864956571 scopus 로고    scopus 로고
    • Toxicity profiles of HER2/neu peptide anticancer vaccines: The picture from phase/I and II clinical trials
    • 22873121 1:CAS:528:DC%2BC38XhtFKjurrJ Epub 2012 Aug 10
    • Baxevanis CN, Papamichail M, Perez SA. Toxicity profiles of HER2/neu peptide anticancer vaccines: the picture from phase/I and II clinical trials. Expert Rev Vaccines. 2012;11(6):637-40. Epub 2012 Aug 10.
    • (2012) Expert Rev Vaccines , vol.11 , Issue.6 , pp. 637-640
    • Baxevanis, C.N.1    Papamichail, M.2    Perez, S.A.3


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