Molecular characterization of gallbladder cancer using somatic mutation profiling

Human Pathology

Volumn 45, Issue 4, 2014, Pages 701-708

  Javle, Milind ^a   Rashid, Asif ^a   Churi, Chaitanya ^a   Kar, Siddhartha ^a   Zuo, Mingxin ^a   Eterovic, Agda Karina ^a   Nogueras Gonzalez, Graciela M ^a   Janku, Filip ^a   Shroff, Rachna T ^a   Aloia, Thomas A ^a   Vauthey, Jean Nicholas ^a   Curley, Steven ^a   Mills, Gordon ^a   Roa, Ivan ^b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b Creative Bioscience   (Chile)

Author keywords

DNA sequencing; Gallbladder neoplasms; Mutational analysis

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; FIBROBLAST GROWTH FACTOR 10; ISOCITRATE DEHYDROGENASE 1; K RAS PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PROTEIN KINASE LKB1; PROTEIN P53; SCATTER FACTOR RECEPTOR; TUBERIN;

ADULT; AGED; ARTICLE; CODING; FEMALE; GALLBLADDER CANCER; GENE AMPLIFICATION; GENE FREQUENCY; GENE FUSION; GENE SEQUENCE; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN TISSUE; MALE; MASS SPECTROMETRY; MIDDLE AGED; MUTATIONAL ANALYSIS; NEXT GENERATION SEQUENCING; ONCOGENE N RAS; SIGNAL TRANSDUCTION; SOMATIC MUTATION; VERY ELDERLY; CANCER SURVIVAL; GENE EXPRESSION PROFILING; HISTOLOGY; MAJOR CLINICAL STUDY; MOLECULAR DIAGNOSIS; ONCOGENE K RAS;

DNA SEQUENCING; GALLBLADDER NEOPLASMS; MUTATIONAL ANALYSIS;

ADULT; AGED; AGED, 80 AND OVER; DNA MUTATIONAL ANALYSIS; FEMALE; FORMALDEHYDE; GALLBLADDER NEOPLASMS; GENE EXPRESSION PROFILING; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MALE; MIDDLE AGED; MUTATION; PARAFFIN EMBEDDING; TISSUE FIXATION;

EID: 84896543721     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2013.11.001     Document Type: Article

References (30)

1. I.I. Wistuba, and A.F. Gazdar Gallbladder cancer: lessons from a rare tumour Nat Rev Cancer 4 2004 695 706 (Pubitemid 39215068)
2. W.A. Zatonski, A.B. Lowenfels, and P. Boyle et al. Epidemiologic aspects of gallbladder cancer: a case-control study of the SEARCH Program of the International Agency for Research on Cancer J Natl Cancer Inst 89 1997 1132 1138 (Pubitemid 27337927)
3. Trial watch: success for crizotinib in ALK-driven cancer Nat Rev Drug Discov 9 2010 908
4. K. Stemke-Hale, K. Shipman, and I. Kitsou-Mylona et al. Frequency of mutations and polymorphisms in borderline ovarian tumors of known cancer genes Mod Pathol 26 2013 544 552
5. L.E. Wang, H. Ma, and K.S. Hale et al. Roles of genetic variants in the PI3K and RAS/RAF pathways in susceptibility to endometrial cancer and clinical outcomes J Cancer Res Clin Oncol 138 2012 377 385
6. A. Andreou, S. Kopetz, and D.M. Maru et al. Adjuvant chemotherapy with FOLFOX for primary colorectal cancer is associated with increased somatic gene mutations and inferior survival in patients undergoing hepatectomy for metachronous liver metastases Ann Surg 256 2012 642 650
7. J.S. Ross, and M. Cronin Whole cancer genome sequencing by next-generation methods Am J Clin Pathol 136 2011 527 539
8. A. Gnirke, A. Melnikov, and J. Maguire et al. Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing Nat Biotechnol 27 2009 182 189
9. H. Li, B. Handsaker, and A. Wysoker et al. The sequence alignment/map format and SAMtools Bioinformatics 25 2009 2078 2079
10. A. McKenna, M. Hanna, and E. Banks et al. The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data Genome Res 20 2010 1297 1303
11. D. Lipson, M. Capelletti, and R. Yelensky et al. Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies Nat Med 18 2012 382 384
12. E.L. Kaplan, and P. Meier Nonparametric estimation from incomplete observations J Am Stat Assoc 53 1958 457 481
13. D.R. Cox Regression models and life tables (with discussion) J R Stat Soc B 34 1972 187 220
14. A.X. Zhu, and A.F. Hezel Development of molecularly targeted therapies in biliary tract cancers: reassessing the challenges and opportunities Hepatology 53 2011 695 704
15. A. Rashid Cellular and molecular biology of biliary tract cancers Surg Oncol Clin N Am 11 2002 995 1009 (Pubitemid 35397235)
16. T. Kawamoto, S. Krishnamurthy, and E. Tarco et al. HER receptor family: novel candidate for targeted therapy for gallbladder and extrahepatic bile duct cancer Gastrointest Cancer Res 1 2007 221 227
17. J.C. Roa, L. Anabalon, and I. Roa et al. Promoter methylation profile in gallbladder cancer J Gastroenterol 41 2006 269 275
18. H.P. Zhang, L. Ruan, and L.M. Zheng et al. Screening for EGFR mutations in lung cancer by a novel real-time PCR with double-loop probe and Sanger DNA sequencing Zhonghua Zhong Liu Za Zhi 35 2013 28 32
19. M. Labussiere, M. Sanson, and A. Idbaih et al. IDH1 gene mutations: a new paradigm in glioma prognosis and therapy? Oncologist 15 2010 196 199
20. G. Marcucci, K. Maharry, and Y.Z. Wu et al. IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study J Clin Oncol 28 2010 2348 2355
21. D.R. Borger, K.K. Tanabe, and K.C. Fan et al. Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping Oncologist 17 2012 72 79
22. K.E. Yen, M.A. Bittinger, and S.M. Su et al. Cancer-associated IDH mutations: biomarker and therapeutic opportunities Oncogene 29 2010 6409 6417
23. P.S. Ward, C. Lu, and J.R. Cross et al. The potential for isocitrate dehydrogenase mutations to produce 2-hydroxyglutarate depends on allele specificity and subcellular compartmentalization J Biol Chem 288 2013 3804 3815
24. G. Andreotti, J. Chen, and Y.T. Gao et al. Polymorphisms of genes in the lipid metabolism pathway and risk of biliary tract cancers and stones: a population-based case-control study in Shanghai, China Cancer Epidemiol Biomarkers Prev 17 2008 525 534 (Pubitemid 351469201)
25. S.K. Park, G. Andreotti, and L.C. Sakoda et al. Variants in hormone-related genes and the risk of biliary tract cancers and stones: a population-based study in China Carcinogenesis 30 2009 606 614
26. K. Srivastava, A. Srivastava, and B. Mittal Polymorphisms in ERCC2, MSH2, and OGG1 DNA repair genes and gallbladder cancer risk in a population of Northern India Cancer 116 2010 3160 3169
27. L.A. Garraway, J. Verweij, and K.V. Ballman Precision oncology: an overview J Clin Oncol 31 2013 1803 1805
28. V.P. Eswarakumar, I. Lax, and J. Schlessinger Cellular signaling by fibroblast growth factor receptors Cytokine Growth Factor Rev 16 2005 139 149 (Pubitemid 40616112)
29. D. Singh, J.M. Chan, and P. Zoppoli et al. Transforming fusions of FGFR and TACC genes in human glioblastoma Science 337 2012 1231 1235
30. Y.M. Wu, F. Su, and S. Kalyana-Sundaram et al. Identification of targetable FGFR gene fusions in diverse cancers Cancer Discov 3 2013 636 647