PINK1/Parkin-mediated mitophagy alleviates chlorpyrifos-induced apoptosis in SH-SY5Y cells

Toxicology

Volumn 334, Issue , 2015, Pages 72-80

  Dai, Hongmei ^a   Deng, Yuanying ^a   Zhang, Jie ^b   Han, Hailong ^c   Zhao, Mingyi ^a   Li, Ying ^a   Zhang, Chen ^a   Tian, Jing ^a   Bing, Guoying ^d   Zhao, Lingling ^a  

^a THE THIRD XIANGYA HOSPITAL OF CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c CENTRAL SOUTH UNIVERSITY   (China)

^d UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Apoptosis; Chlorpyrifos; Mitophagy; PINK1 Parkin

Indexed keywords

CASPASE 3; CHLORPYRIFOS; MITOCHONDRIAL PROTEIN; PARKIN; PINK1 PROTEIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; INSECTICIDE; LIGHT CHAIN 3, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN KINASE; PTEN-INDUCED PUTATIVE KINASE;

APOPTOSIS; ARTICLE; AUTOPHAGOSOME; BRAIN MITOCHONDRION; CELL COUNTING; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DEPOLARIZATION; ENZYME ACTIVATION; GENETIC TRANSFECTION; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOPHAGY; NEUROTOXICITY; PRIORITY JOURNAL; WESTERN BLOTTING; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MITOCHONDRION; NERVE CELL; OXIDATIVE STRESS; PATHOLOGY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME; TUMOR CELL LINE;

APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; CHLORPYRIFOS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INSECTICIDES; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; NEURONS; OXIDATIVE STRESS; PROTEIN KINASES; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION;

EID: 84931262796     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2015.06.003     Document Type: Article

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