Plant extracts from Cameroonian medicinal plants strongly inhibit hepatitis C virus infection in vitro

Frontiers in Microbiology

Volumn 6, Issue MAY, 2015, Pages

  Galani, Borris R T ^a,b   Sahuc, Marie Emmanuelle ^c   Njayou, Frederic N ^a   Deloison, Gaspard ^c   Mkounga, Pierre ^a   Feudjou, William F ^a   Brodin, Priscille ^c   Rouillé, Yves ^c   Nkengfack, Augustin E ^a   Moundipa, Paul Fewou ^a   Séron, Karin ^c  

^a UNIVERSITY OF YAOUNDÉ I   (Cameroon)

^b UNIVERSITY OF NGAOUNDERE   (Cameroon)

^c UNIV LILLE   (France)

Author keywords

Entry inhibitor; Hepatitis C; Natural compounds; Plant extract; Traditional medicine

Indexed keywords

ALCOHOL; DETARIUM MICROCARPUM EXTRACT; PHRAGMANTHERA CAPITATA EXTRACT; PLANT EXTRACT; TRICHILIA DREGEANA EXTRACT; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CAMEROONIAN; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DETARIUM MICROCARPUM; DOSE RESPONSE; HEPATITIS C; HUMAN; HUMAN CELL; IC50; IMMUNOFLUORESCENCE; NONHUMAN; PHRAGMANTHERA CAPITATA; PLANT LEAF; PLANT ROOT; PLANT STEM; TRICHILIA DREGEANA; VIRUS ASSEMBLY; VIRUS ENTRY;

CAPITATA; DETARIUM MICROCARPUM; HEPATITIS C VIRUS; TRICHILIA DREGEANA;

EID: 84931261636     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2015.00488     Document Type: Article

References (32)

1. Abreu, P., and Relva, A. (2002). Carbohydrates from Detarium microcarpum bark extract. Carbohydr. Res. 337, 1663-1666. doi: 10.1016/S0008-6215(02)00025-3.
2. Anggakusuma, Colpitts, C. C., Schang, L. M., Rachmawati, H., Frentzen, A., Pfaender, S., et al. (2013). Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells. Gut 63, 1137-1149. doi: 10.1136/gutjnl-2012-304299.
3. Calland, N., Albecka, A., Belouzard, S., Wychowski, C., Duverlie, G., Descamps, V., et al. (2012a). (-)-Epigallocatechin-3-gallate is a new inhibitor of hepatitis C virus entry. Hepatology 55, 720-729. doi: 10.1002/hep.24803.
4. Calland, N., Dubuisson, J., Rouillé, Y., and Séron, K. (2012b). Hepatitis C virus and natural compounds: a new antiviral approach? Viruses 4, 2197-2217. doi: 10.3390/v4102197.
5. Cavin, A. L., Hay, A. E., Marston, A., Stoeckli-Evans, H., Scopelliti, R., Diallo, D., et al. (2006). Bioactive diterpenes from the fruits of Detarium microcarpum. J. Nat. Prod. 69, 768-773. doi: 10.1021/np058123q.
6. Chen, C., Qiu, H., Gong, J., Liu, Q., Xiao, H., Chen, X. W., et al. (2012). (-)-Epigallocatechin-3-gallate inhibits the replication cycle of hepatitis C virus. Arch. Virol. 157, 1301-1312. doi: 10.1007/s00705-012-1304-0.
7. Ciesek, S., Von Hahn, T., Colpitts, C. C., Schang, L. M., Friesland, M., Steinmann, J., et al. (2011). The green tea polyphenol, epigallocatechin-3-gallate, inhibits hepatitis C virus entry. Hepatology 54, 1947-1955. doi: 10.1002/hep.24610.
8. Delgrange, D., Pillez, A., Castelain, S., Cocquerel, L., Rouillé, Y., Dubuisson, J., et al. (2007). Robust production of infectious viral particles in Huh-7 cells by introducing mutations in hepatitis C virus structural proteins. J. Gen. Virol. 88, 2495-2503. doi: 10.1099/vir.0.82872-0.
9. Dubuisson, J., Hsu, H. H., Cheung, R. C., Greenberg, H. B., Russell, D. G., and Rice, C. M. (1994). Formation and intracellular localization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia and Sindbis viruses. J. Virol. 68, 6147-6160.
10. Galani Tietcheu, B. R., Sass, G., Njayou, N. F., Mkounga, P., Tiegs, G., and Moundipa, P. F. (2014). Anti-hepatitis C virus activity of crude extract and fractions of Entada africana in genotype 1b replicon systems. Am. J. Chin. Med. 42, 853-868. doi: 10.1142/S0192415X14500542.
11. Goueslain, L., Alsaleh, K., Horellou, P., Roingeard, P., Descamps, V., Duverlie, G., et al. (2010). Identification of GBF1 as a cellular factor required for hepatitis C virus RNA replication. J. Virol. 84, 773-787. doi: 10.1128/JVI.01190-09.
12. Haid, S., Novodomska, A., Gentzsch, J., Grethe, C., Geuenich, S., Bankwitz, D., et al. (2012). A plant-derived flavonoid inhibits entry of all HCV genotypes into human hepatocytes. Gastroenterology 143, 213-222 e215. doi: 10.1053/j.gastro.2012.03.036.
13. Keating, G. M. (2015). Ledipasvir/Sofosbuvir: a review of its use in chronic hepatitis C. Drugs 75, 675-685. doi: 10.1007/s40265-015-0381-2.
14. Lamien-Meda, A., Lamien, C. E., Compaore, M. M., Meda, R. N., Kiendrebeogo, M., Zeba, B., et al. (2008). Polyphenol content and antioxidant activity of fourteen wild edible fruits from Burkina Faso. Molecules 13, 581-594. doi: 10.3390/molecules13030581.
15. Lavanchy, D. (2011). Evolving epidemiology of hepatitis C virus. Clin. Microbiol. Infect 17, 107-115. doi: 10.1111/j.1469-0691.2010.03432.x.
16. Li, C., Njouom, R., Pepin, J., Nakano, T., Bennett, P., Pybus, O. G., et al. (2013). Characterization of full-length hepatitis C virus sequences for subtypes 1e, 1h and 1l, and a novel variant revealed Cameroon as an area in origin for genotype 1. J. Gen. Virol. 94, 1780-1790. doi: 10.1099/vir.0.048835-0.
17. Mauss, S., Berg, T., Rockstroh, J., Sarrazin, C., and Wedemeyer, H. (2013). Short Guide to Hepatitis C. Bondi Junction, NSW: Flying publisher.
18. Moghadamtousi, S. Z., Kamarudin, M. N., Chan, C. K., Goh, B. H., and Kadir, H. A. (2014). Phytochemistry and biology of Loranthus parasiticus Merr, a commonly used herbal medicine. Am. J. Chin. Med. 42, 23-35. doi: 10.1142/S0192415X14500025.
19. Nakabayashi, H., Taketa, K., Miyano, K., Yamane, T., and Sato, J. (1982). Growth of human hepatoma cells lines with differentiated functions in chemically defined medium. Cancer Res. 42, 3858-3863.
20. Ndjomou, J., Kupfer, B., Kochan, B., Zekeng, L., Kaptue, L., and Matz, B. (2002). Hepatitis C virus infection and genotypes among human immunodeficiency virus high-risk groups in Cameroon. J. Med. Virol. 66, 179-186. doi: 10.1002/jmv.2128.
21. Nerrienet, E., Pouillot, R., Lachenal, G., Njouom, R., Mfoupouendoun, J., Bilong, C., et al. (2005). Hepatitis C virus infection in cameroon: a cohort-effect. J. Med. Virol. 76, 208-214. doi: 10.1002/jmv.20343.
22. Njayou, F. N., Moundipa, P. F., Tchana, A. N., Ngadjui, B. T., and Tchouanguep, F. M. (2008). Inhibition of microsomal lipid peroxidation and protein oxidation by extracts from plants used in Bamun folk medicine (Cameroon) against hepatitis. Afr. J. Tradit. Complement. Altern. Med. 5, 278-289. doi: 10.4314/ajtcam.v5i3.31284.
23. Njoya, O., Ntchama, L., Tagni, M., Dang, I., and Kowo, M. (2013). Relapses in the treatment of genotype 2 viral hepatitis C, a cause of concern in the blacks. Indian J. Gastroenterol. 33, 292. doi: 10.1007/s12664-013-0385-3.
24. Petrera, E., and Coto, C. E. (2009). Therapeutic effect of meliacine, an antiviral derived from Melia azedarach L., in mice genital herpetic infection. Phytother. Res. 23, 1771-1777. doi: 10.1002/ptr.2850.
25. Rouille, Y., Helle, F., Delgrange, D., Roingeard, P., Voisset, C., Blanchard, E., et al. (2006). Subcellular localization of hepatitis C virus structural proteins in a cell culture system that efficiently replicates the virus. J. Virol. 80, 2832-2841. doi: 10.1128/JVI.80.6.2832-2841.2006.
26. Sangiovanni, A., Prati, G. M., Fasani, P., Ronchi, G., Romeo, R., Manini, M., et al. (2006). The natural history of compensated cirrhosis due to hepatitis C virus: a 17-year cohort study of 214 patients. Hepatology 43, 1303-1310. doi: 10.1002/hep.21176.
27. Sarrazin, C., Hezode, C., Zeuzem, S., and Pawlotsky, J. M. (2012). Antiviral strategies in hepatitis C virus infection. J. Hepatol. 56(Suppl. 1), S88-S100. doi: 10.1016/S0168-8278(12)60010-5.
28. Tiwari, V., Darmani, N. A., Yue, B. Y., and Shukla, D. (2010). In vitro antiviral activity of neem (Azardirachta indica L.) bark extract against herpes simplex virus type-1 infection. Phytother. Res. 24, 1132-1140. doi: 10.1002/ptr.3085.
29. Wahyuni, T. S., Tumewu, L., Permanasari, A. A., Apriani, E., Adianti, M., Rahman, A., et al. (2013). Antiviral activities of Indonesian medicinal plants in the East Java region against hepatitis C virus. Virol. J. 10, 259. doi: 10.1186/1743-422X-10-259.
30. Wang, Z. J., Yang, Z. Q., Huang, T. N., Wen, L., and Liu, Y. W. (2000). [Experimental research on inhibitory effect of alcohol extracts from Loranthus yadoriki Sieb. on coxsackie B3 virus]. Zhongguo Zhong Yao Za Zhi 25, 685-687.
31. Wong, D. Z., Kadir, H. A., and Ling, S. K. (2012). Bioassay-guided isolation of neuroprotective compounds from Loranthus parasiticus against H(2)O(2)-induced oxidative damage in NG108-15 cells. J. Ethnopharmacol. 139, 256-264. doi: 10.1016/j.jep.2011.11.010.
32. Wu, S. F., Lin, C. K., Chuang, Y. S., Chang, F. R., Tseng, C. K., Wu, Y. C., et al. (2012). Anti-hepatitis C virus activity of 3-hydroxy caruilignan C from Swietenia macrophylla stems. J. Viral Hepat. 19, 364-370. doi: 10.1111/j.1365-2893.2011.01558.x.