Simultaneous pharmacokinetic modeling of gentamicin, tobramycin and vancomycin clearance from neonates to adults: Towards a semi-physiological function for maturation in glomerular filtration

Pharmaceutical Research

Volumn 31, Issue 10, 2014, Pages 2643-2654

  De Cock, Roosmarijn F W ^a   Allegaert, Karel ^b   Brussee, Janneke M ^a   Sherwin, Catherine M T ^c   Mulla, Hussain ^d   De Hoog, Matthijs ^e   Van Den Anker, Johannes N ^e,f   Danhof, Meindert ^a   Knibbe, Catherijne A J ^a,g  

^a LEIDEN UNIVERSITY   (Netherlands)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY HOSPITALS OF LEICESTER NHS TRUST   (United Kingdom)

^e SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^f CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^g ST ANTONIUS HOSPITAL   (Netherlands)

Author keywords

antibiotics; developmental changes; glomerular filtration; pediatric age range

Indexed keywords

CREATININE; GENTAMICIN; TOBRAMYCIN; VANCOMYCIN;

ADOLESCENT; ADULT; AGING; BIOLOGICAL MODEL; BLOOD; BODY WEIGHT; CHILD; GLOMERULUS FILTRATION RATE; HUMAN; INFANT; METABOLIC CLEARANCE RATE; NEWBORN; PHYSIOLOGY; PRESCHOOL CHILD;

ADOLESCENT; ADULT; AGING; BODY WEIGHT; CHILD; CHILD, PRESCHOOL; CREATININE; GENTAMICINS; GLOMERULAR FILTRATION RATE; HUMANS; INFANT; INFANT, NEWBORN; METABOLIC CLEARANCE RATE; MODELS, BIOLOGICAL; TOBRAMYCIN; VANCOMYCIN;

EID: 84931098560     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-014-1361-z     Document Type: Article

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