메뉴 건너뛰기




Volumn 6, Issue 15, 2015, Pages 13506-13519

PDL1 expression in inflammatory breast cancer is frequent and predicts for the pathological response to chemotherapy

Author keywords

Chemotherapy; Immune response; Inflammatory breast cancer; PDL1; survival

Indexed keywords

ANTHRACYCLINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; MESSENGER RNA; PROGRAMMED DEATH 1 LIGAND 1; TAXANE DERIVATIVE; TRASTUZUMAB; PDCD1 PROTEIN, HUMAN; PROGRAMMED DEATH 1 RECEPTOR;

EID: 84931073954     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3642     Document Type: Article
Times cited : (107)

References (79)
  • 3
    • 84920001154 scopus 로고    scopus 로고
    • Systemic treatments of inflammatory breast cancer: an overview
    • Monneur A, Bertucci F, Viens P, Goncalves A. Systemic treatments of inflammatory breast cancer: an overview. Bull Cancer. 2014; 101: 1080-1088.
    • (2014) Bull Cancer. , vol.101 , pp. 1080-1088
    • Monneur, A.1    Bertucci, F.2    Viens, P.3    Goncalves, A.4
  • 4
    • 77952723968 scopus 로고    scopus 로고
    • Systemic therapy of inflammatory breast cancer from high-dose chemotherapy to targeted therapies: the French experience
    • Viens P, Tarpin C, Roche H, Bertucci F. Systemic therapy of inflammatory breast cancer from high-dose chemotherapy to targeted therapies: the French experience. Cancer. 2010; 116: 2829-2836.
    • (2010) Cancer. , vol.116 , pp. 2829-2836
    • Viens, P.1    Tarpin, C.2    Roche, H.3    Bertucci, F.4
  • 6
    • 39649105682 scopus 로고    scopus 로고
    • Genetic determinants of aggressive breast cancer
    • Ventura AC, Merajver SD. Genetic determinants of aggressive breast cancer. Annu Rev Med. 2008; 59: 199-212.
    • (2008) Annu Rev Med. , vol.59 , pp. 199-212
    • Ventura, A.C.1    Merajver, S.D.2
  • 12
    • 34648829133 scopus 로고    scopus 로고
    • An immune response gene expression module identifies a good prognosis subtype in estrogen receptor negative breast cancer
    • Teschendorff AE, Miremadi A, Pinder SE, Ellis IO, Caldas C. An immune response gene expression module identifies a good prognosis subtype in estrogen receptor negative breast cancer. Genome Biol. 2007; 8: R157.
    • (2007) Genome Biol. , vol.8 , pp. R157
    • Teschendorff, A.E.1    Miremadi, A.2    Pinder, S.E.3    Ellis, I.O.4    Caldas, C.5
  • 18
    • 70349569569 scopus 로고    scopus 로고
    • Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
    • Ahmadzadeh M, Johnson LA, Heemskerk B, Wunderlich JR, Dudley ME, White DE, Rosenberg SA. Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired. Blood. 2009; 114: 1537-1544.
    • (2009) Blood. , vol.114 , pp. 1537-1544
    • Ahmadzadeh, M.1    Johnson, L.A.2    Heemskerk, B.3    Wunderlich, J.R.4    Dudley, M.E.5    White, D.E.6    Rosenberg, S.A.7
  • 21
    • 79952114884 scopus 로고    scopus 로고
    • B7-H1 expression on non-B and non-T cells promotes distinct effects on T- and B-cell responses in autoimmune arthritis
    • Hamel KM, Cao Y, Wang Y, Rodeghero R, Kobezda T, Chen L, Finnegan A. B7-H1 expression on non-B and non-T cells promotes distinct effects on T- and B-cell responses in autoimmune arthritis. Eur J Immunol. 2010; 40: 3117-3127.
    • (2010) Eur J Immunol. , vol.40 , pp. 3117-3127
    • Hamel, K.M.1    Cao, Y.2    Wang, Y.3    Rodeghero, R.4    Kobezda, T.5    Chen, L.6    Finnegan, A.7
  • 22
    • 44349150012 scopus 로고    scopus 로고
    • Inhibitory B7-family molecules in the tumour microenvironment
    • Zou W, Chen L. Inhibitory B7-family molecules in the tumour microenvironment. Nat Rev Immunol. 2008; 8: 467-477.
    • (2008) Nat Rev Immunol. , vol.8 , pp. 467-477
    • Zou, W.1    Chen, L.2
  • 23
    • 0037126021 scopus 로고    scopus 로고
    • Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
    • Iwai Y, Ishida M, Tanaka Y, Okazaki T, Honjo T, Minato N. Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc Natl Acad Sci U S A. 2002; 99: 12293-12297.
    • (2002) Proc Natl Acad Sci U S A. , vol.99 , pp. 12293-12297
    • Iwai, Y.1    Ishida, M.2    Tanaka, Y.3    Okazaki, T.4    Honjo, T.5    Minato, N.6
  • 24
    • 84900430387 scopus 로고    scopus 로고
    • Harnessing the power of the immune system via blockade of PD-1 and PD-L1: a promising new anticancer strategy
    • Reiss KA, Forde PM, Brahmer JR. Harnessing the power of the immune system via blockade of PD-1 and PD-L1: a promising new anticancer strategy. Immunotherapy. 2014; 6: 459-475.
    • (2014) Immunotherapy. , vol.6 , pp. 459-475
    • Reiss, K.A.1    Forde, P.M.2    Brahmer, J.R.3
  • 31
    • 4243096258 scopus 로고    scopus 로고
    • B7-H1 expression on non-small cell lung cancer cells and its relationship with tumor-infiltrating lymphocytes and their PD-1 expression
    • Konishi J, Yamazaki K, Azuma M, Kinoshita I, Dosaka-Akita H, Nishimura M. B7-H1 expression on non-small cell lung cancer cells and its relationship with tumor-infiltrating lymphocytes and their PD-1 expression. Clin Cancer Res. 2004; 10: 5094-5100.
    • (2004) Clin Cancer Res. , vol.10 , pp. 5094-5100
    • Konishi, J.1    Yamazaki, K.2    Azuma, M.3    Kinoshita, I.4    Dosaka-Akita, H.5    Nishimura, M.6
  • 35
    • 34250177269 scopus 로고    scopus 로고
    • PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma
    • Thompson RH, Dong H, Lohse CM, Leibovich BC, Blute ML, Cheville JC, Kwon ED. PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma. Clin Cancer Res. 2007; 13: 1757-1761.
    • (2007) Clin Cancer Res. , vol.13 , pp. 1757-1761
    • Thompson, R.H.1    Dong, H.2    Lohse, C.M.3    Leibovich, B.C.4    Blute, M.L.5    Cheville, J.C.6    Kwon, E.D.7
  • 41
    • 84883863501 scopus 로고    scopus 로고
    • Up-regulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells
    • Spranger S, Spaapen RM, Zha Y, Williams J, Meng Y, Ha TT, Gajewski TF. Up-regulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells. Sci Transl Med. 2013; 5: 200ra116.
    • (2013) Sci Transl Med. , vol.5 , pp. 200ra116
    • Spranger, S.1    Spaapen, R.M.2    Zha, Y.3    Williams, J.4    Meng, Y.5    Ha, T.T.6    Gajewski, T.F.7
  • 43
    • 42049111164 scopus 로고    scopus 로고
    • FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy
    • Ghebeh H, Barhoush E, Tulbah A, Elkum N, Al-Tweigeri T, Dermime S. FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy. BMC Cancer. 2008; 8: 57.
    • (2008) BMC Cancer. , vol.8 , pp. 57
    • Ghebeh, H.1    Barhoush, E.2    Tulbah, A.3    Elkum, N.4    Al-Tweigeri, T.5    Dermime, S.6
  • 45
    • 34547098581 scopus 로고    scopus 로고
    • Expression of B7-H1 in breast cancer patients is strongly associated with high proliferative Ki-67-expressing tumor cells
    • Ghebeh H, Tulbah A, Mohammed S, Elkum N, Bin Amer SM, Al-Tweigeri T, Dermime S. Expression of B7-H1 in breast cancer patients is strongly associated with high proliferative Ki-67-expressing tumor cells. Int J Cancer. 2007; 121: 751-758.
    • (2007) Int J Cancer. , vol.121 , pp. 751-758
    • Ghebeh, H.1    Tulbah, A.2    Mohammed, S.3    Elkum, N.4    Bin Amer, S.M.5    Al-Tweigeri, T.6    Dermime, S.7
  • 46
    • 84901044976 scopus 로고    scopus 로고
    • In situ tumor PD-L1 mRNA expression is associated with increased TILs and better outcome in breast carcinomas
    • Schalper KA, Velcheti V, Carvajal D, Wimberly H, Brown J, Pusztai L, Rimm DL. In situ tumor PD-L1 mRNA expression is associated with increased TILs and better outcome in breast carcinomas. Clin Cancer Res. 2014; 20: 2773-2782.
    • (2014) Clin Cancer Res. , vol.20 , pp. 2773-2782
    • Schalper, K.A.1    Velcheti, V.2    Carvajal, D.3    Wimberly, H.4    Brown, J.5    Pusztai, L.6    Rimm, D.L.7
  • 47
    • 84895779425 scopus 로고    scopus 로고
    • PD-L1 expression is increased in a subset of basal type breast cancer cells
    • Soliman H, Khalil F, Antonia S. PD-L1 expression is increased in a subset of basal type breast cancer cells. PLoS One. 2014; 9: e88557.
    • (2014) PLoS One. , vol.9 , pp. e88557
    • Soliman, H.1    Khalil, F.2    Antonia, S.3
  • 52
    • 33745259517 scopus 로고    scopus 로고
    • Cell-type specific gene expression profiles of leukocytes in human peripheral blood
    • Palmer C, Diehn M, Alizadeh AA, Brown PO. Cell-type specific gene expression profiles of leukocytes in human peripheral blood. BMC Genomics. 2006; 7: 115.
    • (2006) BMC Genomics. , vol.7 , pp. 115
    • Palmer, C.1    Diehn, M.2    Alizadeh, A.A.3    Brown, P.O.4
  • 57
    • 84925545111 scopus 로고    scopus 로고
    • Clinical blockade of PD1 and LAG3 - potential mechanisms of action
    • Nguyen LT, Ohashi PS. Clinical blockade of PD1 and LAG3 - potential mechanisms of action. Nat Rev Immunol. 2014; 15: 45-56.
    • (2014) Nat Rev Immunol. , vol.15 , pp. 45-56
    • Nguyen, L.T.1    Ohashi, P.S.2
  • 58
    • 84901620362 scopus 로고    scopus 로고
    • T helper responses are maintained by basal-like breast cancer cells and confer to immune modulation via upregulation of PD-1 ligands
    • Karasar P, Esendagli G. T helper responses are maintained by basal-like breast cancer cells and confer to immune modulation via upregulation of PD-1 ligands. Breast Cancer Res Treat. 2014; 145: 605-614.
    • (2014) Breast Cancer Res Treat. , vol.145 , pp. 605-614
    • Karasar, P.1    Esendagli, G.2
  • 59
    • 84875722651 scopus 로고    scopus 로고
    • Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98
    • Loi S, Sirtaine N, Piette F, Salgado R, Viale G, Van Eenoo F, Rouas G, Francis P, Crown JP, Hitre E, de Azambuja E, Quinaux E, Di Leo A, et al. Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98. J Clin Oncol. 2013; 31: 860-867.
    • (2013) J Clin Oncol. , vol.31 , pp. 860-867
    • Loi, S.1    Sirtaine, N.2    Piette, F.3    Salgado, R.4    Viale, G.5    Van Eenoo, F.6    Rouas, G.7    Francis, P.8    Crown, J.P.9    Hitre, E.10    de Azambuja, E.11    Quinaux, E.12    Di Leo, A.13
  • 61
    • 82955217260 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer
    • West NR, Milne K, Truong PT, Macpherson N, Nelson BH, Watson PH. Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer. Breast Cancer Res. 2011; 13: R126.
    • (2011) Breast Cancer Res. , vol.13 , pp. R126
    • West, N.R.1    Milne, K.2    Truong, P.T.3    Macpherson, N.4    Nelson, B.H.5    Watson, P.H.6
  • 64
    • 84872608638 scopus 로고    scopus 로고
    • Tumour-infiltrating FOXP3(+) lymphocytes are associated with cytotoxic immune responses and good clinical outcome in oestrogen receptor-negative breast cancer
    • West NR, Kost SE, Martin SD, Milne K, Deleeuw RJ, Nelson BH, Watson PH. Tumour-infiltrating FOXP3(+) lymphocytes are associated with cytotoxic immune responses and good clinical outcome in oestrogen receptor-negative breast cancer. Br J Cancer. 2013; 108: 155-162.
    • (2013) Br J Cancer. , vol.108 , pp. 155-162
    • West, N.R.1    Kost, S.E.2    Martin, S.D.3    Milne, K.4    Deleeuw, R.J.5    Nelson, B.H.6    Watson, P.H.7
  • 66
    • 79953832076 scopus 로고    scopus 로고
    • Mechanism of synergistic effect of chemotherapy and immunotherapy of cancer
    • Ramakrishnan R, Gabrilovich DI. Mechanism of synergistic effect of chemotherapy and immunotherapy of cancer. Cancer Immunol Immunoth. 2011; 60: 419-423.
    • (2011) Cancer Immunol Immunoth. , vol.60 , pp. 419-423
    • Ramakrishnan, R.1    Gabrilovich, D.I.2
  • 71
    • 33845432928 scopus 로고    scopus 로고
    • Adjusting batch effects in microarray expression data using empirical Bayes methods
    • Johnson WE, Li C, Rabinovic A. Adjusting batch effects in microarray expression data using empirical Bayes methods. Biostatistics. 2007; 8: 118-127.
    • (2007) Biostatistics. , vol.8 , pp. 118-127
    • Johnson, W.E.1    Li, C.2    Rabinovic, A.3
  • 74
    • 79960015997 scopus 로고    scopus 로고
    • Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
    • Lehmann BD, Bauer JA, Chen X, Sanders ME, Chakravarthy AB, Shyr Y, Pietenpol JA. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Invest. 2011; 121: 2750-2767.
    • (2011) J Clin Invest. , vol.121 , pp. 2750-2767
    • Lehmann, B.D.1    Bauer, J.A.2    Chen, X.3    Sanders, M.E.4    Chakravarthy, A.B.5    Shyr, Y.6    Pietenpol, J.A.7
  • 78
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • Tusher VG, Tibshirani R, Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A. 2001; 98: 5116-5121.
    • (2001) Proc Natl Acad Sci U S A. , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 79
    • 24944452378 scopus 로고    scopus 로고
    • REporting recommendations for tumour MARKer prognostic studies (REMARK)
    • McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM and Statistics Subcommittee of the NCIEWGoCD. REporting recommendations for tumour MARKer prognostic studies (REMARK). Br J Cancer. 2005; 93: 387-391.
    • (2005) Br J Cancer. , vol.93 , pp. 387-391
    • McShane, L.M.1    Altman, D.G.2    Sauerbrei, W.3    Taube, S.E.4    Gion, M.5    Clark, G.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.