-
1
-
-
84919701009
-
Cancer Facts & Figures 2014.
-
Atlanta: American Cancer Society
-
American Cancer Society. Cancer Facts & Figures 2014. Atlanta: American Cancer Society; 2014.
-
(2014)
-
-
-
2
-
-
0036675220
-
Metastasis to bone: causes, consequences and therapeutic opportunities
-
Mundy GR. Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer. 2002; 2:584-593.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 584-593
-
-
Mundy, G.R.1
-
3
-
-
33750726077
-
Clinical features of metastatic bone disease and risk of skeletal morbidity
-
Coleman RE. Clinical features of metastatic bone disease and risk of skeletal morbidity. Clin Cancer Res. 2006; 12:6243s-6249s.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6243s-6249s
-
-
Coleman, R.E.1
-
4
-
-
84873050284
-
Regulatory networks defining EMT during cancer initiation and progression
-
De Craene B, Berx G. Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer. 2013; 13:97-110.
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 97-110
-
-
De Craene, B.1
Berx, G.2
-
5
-
-
70450198396
-
Epithelialmesenchymal transitions in development and disease
-
Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelialmesenchymal transitions in development and disease. Cell. 2009; 139:871-890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
6
-
-
36348994426
-
Pre- EMTing metastasis? Recapitulation of morphogenetic processes in cancer
-
Berx G, Raspe E, Christofori G, Thiery JP, Sleeman JP. Pre- EMTing metastasis? Recapitulation of morphogenetic processes in cancer. Clin Exp Metastasis. 2007; 24:587-597.
-
(2007)
Clin Exp Metastasis
, vol.24
, pp. 587-597
-
-
Berx, G.1
Raspe, E.2
Christofori, G.3
Thiery, J.P.4
Sleeman, J.P.5
-
7
-
-
0038324070
-
Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins
-
Postigo AA, Depp JL, Taylor JJ, Kroll KL. Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins. EMBO J. 2003; 22:2453-2462.
-
(2003)
EMBO J
, vol.22
, pp. 2453-2462
-
-
Postigo, A.A.1
Depp, J.L.2
Taylor, J.J.3
Kroll, K.L.4
-
8
-
-
33745505315
-
DeltaEF1 mediates TGF-beta signaling in vascular smooth muscle cell differentiation
-
Nishimura G, Manabe I, Tsushima K, Fujiu K, Oishi Y, Imai Y, Maemura K, Miyagishi M, Higashi Y, Kondoh H, Nagai R. DeltaEF1 mediates TGF-beta signaling in vascular smooth muscle cell differentiation. Dev Cell. 2006; 11:93-104.
-
(2006)
Dev Cell
, vol.11
, pp. 93-104
-
-
Nishimura, G.1
Manabe, I.2
Tsushima, K.3
Fujiu, K.4
Oishi, Y.5
Imai, Y.6
Maemura, K.7
Miyagishi, M.8
Higashi, Y.9
Kondoh, H.10
Nagai, R.11
-
9
-
-
84874927009
-
ZEB1 Promotes invasiveness of colorectal carcinoma cells through the opposing regulation of uPA and PAI-1
-
Sanchez-Tillo E, de Barrios O, Siles L, Amendola PG, Darling DS, Cuatrecasas M, Castells A, Postigo A. ZEB1 Promotes invasiveness of colorectal carcinoma cells through the opposing regulation of uPA and PAI-1. Clin Cancer Res. 2013; 19:1071-1082.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 1071-1082
-
-
Sanchez-Tillo, E.1
de Barrios, O.2
Siles, L.3
Amendola, P.G.4
Darling, D.S.5
Cuatrecasas, M.6
Castells, A.7
Postigo, A.8
-
10
-
-
43049165453
-
The epithelialmesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, Campbell LL, Polyak K, Brisken C, et al. The epithelialmesenchymal transition generates cells with properties of stem cells. Cell. 2008; 133:704-715.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
Campbell, L.L.11
Polyak, K.12
Brisken, C.13
-
11
-
-
73049110243
-
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
-
Wellner U, Schubert J, Burk UC, Schmalhofer O, Zhu F, Sonntag A, Waldvogel B, Vannier C, Darling D, zur Hausen A, Brunton VG, Morton J, Sansom O, et al. The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat Cell Biol. 2009; 11:1487-1495.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1487-1495
-
-
Wellner, U.1
Schubert, J.2
Burk, U.C.3
Schmalhofer, O.4
Zhu, F.5
Sonntag, A.6
Waldvogel, B.7
Vannier, C.8
Darling, D.9
Zur Hausen, A.10
Brunton, V.G.11
Morton, J.12
Sansom, O.13
-
12
-
-
25444495269
-
Opinion: migrating cancer stem cells-an integrated concept of malignant tumour progression
-
Brabletz T, Jung A, Spaderna S, Hlubek F, Kirchner T. Opinion: migrating cancer stem cells-an integrated concept of malignant tumour progression. Nat Rev Cancer. 2005; 5:744-749.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 744-749
-
-
Brabletz, T.1
Jung, A.2
Spaderna, S.3
Hlubek, F.4
Kirchner, T.5
-
13
-
-
44649163918
-
A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
-
Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna S, Brabletz T. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep. 2008; 9:582-589.
-
(2008)
EMBO Rep
, vol.9
, pp. 582-589
-
-
Burk, U.1
Schubert, J.2
Wellner, U.3
Schmalhofer, O.4
Vincan, E.5
Spaderna, S.6
Brabletz, T.7
-
14
-
-
54049084380
-
A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition
-
Bracken CP, Gregory PA, Kolesnikoff N, Bert AG, Wang J, Shannon MF, Goodall GJ. A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res. 2008; 68:7846-7854.
-
(2008)
Cancer Res
, vol.68
, pp. 7846-7854
-
-
Bracken, C.P.1
Gregory, P.A.2
Kolesnikoff, N.3
Bert, A.G.4
Wang, J.5
Shannon, M.F.6
Goodall, G.J.7
-
15
-
-
69549131213
-
Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features
-
Creighton CJ, Li X, Landis M, Dixon JM, Neumeister VM, Sjolund A, Rimm DL, Wong H, Rodriguez A, Herschkowitz JI, Fan C, Zhang X, He X, et al. Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci U S A. 2009; 106:13820-13825.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 13820-13825
-
-
Creighton, C.J.1
Li, X.2
Landis, M.3
Dixon, J.M.4
Neumeister, V.M.5
Sjolund, A.6
Rimm, D.L.7
Wong, H.8
Rodriguez, A.9
Herschkowitz, J.I.10
Fan, C.11
Zhang, X.12
He, X.13
-
16
-
-
47549102418
-
Epithelial mesenchymal transition traits in human breast cancer cell lines
-
Blick T, Widodo E, Hugo H, Waltham M, Lenburg ME, Neve RM, Thompson EW. Epithelial mesenchymal transition traits in human breast cancer cell lines. Clin Exp Metastasis. 2008; 25:629-642.
-
(2008)
Clin Exp Metastasis
, vol.25
, pp. 629-642
-
-
Blick, T.1
Widodo, E.2
Hugo, H.3
Waltham, M.4
Lenburg, M.E.5
Neve, R.M.6
Thompson, E.W.7
-
17
-
-
0038488950
-
A multigenic program mediating breast cancer metastasis to bone
-
Kang Y, Siegel PM, Shu W, Drobnjak M, Kakonen SM, Cordon-Cardo C, Guise TA, Massague J. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell. 2003; 3:537-549.
-
(2003)
Cancer Cell
, vol.3
, pp. 537-549
-
-
Kang, Y.1
Siegel, P.M.2
Shu, W.3
Drobnjak, M.4
Kakonen, S.M.5
Cordon-Cardo, C.6
Guise, T.A.7
Massague, J.8
-
18
-
-
23144461051
-
Genes that mediate breast cancer metastasis to lung
-
Minn AJ, Gupta GP, Siegel PM, Bos PD, Shu W, Giri DD, Viale A, Olshen AB, Gerald WL, Massague J. Genes that mediate breast cancer metastasis to lung. Nature. 2005; 436:518-524.
-
(2005)
Nature
, vol.436
, pp. 518-524
-
-
Minn, A.J.1
Gupta, G.P.2
Siegel, P.M.3
Bos, P.D.4
Shu, W.5
Giri, D.D.6
Viale, A.7
Olshen, A.B.8
Gerald, W.L.9
Massague, J.10
-
19
-
-
67649300721
-
Genes that mediate breast cancer metastasis to the brain
-
Bos PD, Zhang XH, Nadal C, Shu W, Gomis RR, Nguyen DX, Minn AJ, van de Vijver MJ, Gerald WL, Foekens JA, Massague J. Genes that mediate breast cancer metastasis to the brain. Nature. 2009; 459:1005-1009.
-
(2009)
Nature
, vol.459
, pp. 1005-1009
-
-
Bos, P.D.1
Zhang, X.H.2
Nadal, C.3
Shu, W.4
Gomis, R.R.5
Nguyen, D.X.6
Minn, A.J.7
van de Vijver, M.J.8
Gerald, W.L.9
Foekens, J.A.10
Massague, J.11
-
20
-
-
84868022300
-
SnapShot: Bone Metastasis
-
Ell B, Kang Y. SnapShot: Bone Metastasis. Cell. 2012; 151:690-690. e691.
-
(2012)
Cell
, vol.151
, pp. 690-690. e691
-
-
Ell, B.1
Kang, Y.2
-
21
-
-
79952489285
-
deltaEF1 promotes osteolytic metastasis of MDA-MB-231 breast cancer cells by regulating MMP-1 expression
-
Hu F, Wang C, Guo S, Sun W, Mi D, Gao Y, Zhang J, Zhu T, Yang S. deltaEF1 promotes osteolytic metastasis of MDA-MB-231 breast cancer cells by regulating MMP-1 expression. Biochim Biophys Acta. 2011; 1809:200-210.
-
(2011)
Biochim Biophys Acta
, vol.1809
, pp. 200-210
-
-
Hu, F.1
Wang, C.2
Guo, S.3
Sun, W.4
Mi, D.5
Gao, Y.6
Zhang, J.7
Zhu, T.8
Yang, S.9
-
22
-
-
0030427867
-
Signal transduction by members of the transforming growth factor-beta superfamily
-
Attisano L, Wrana JL. Signal transduction by members of the transforming growth factor-beta superfamily. Cytokine Growth Factor Rev. 1996; 7:327-339.
-
(1996)
Cytokine Growth Factor Rev
, vol.7
, pp. 327-339
-
-
Attisano, L.1
Wrana, J.L.2
-
23
-
-
34250019537
-
Bone: formation by autoinduction
-
Urist MR. Bone: formation by autoinduction. Science. 1965; 150:893-899.
-
(1965)
Science
, vol.150
, pp. 893-899
-
-
Urist, M.R.1
-
24
-
-
0242668869
-
Bone morphogenetic proteins, their antagonists, and the skeleton
-
Canalis E, Economides AN, Gazzerro E. Bone morphogenetic proteins, their antagonists, and the skeleton. Endocr Rev. 2003; 24:218-235.
-
(2003)
Endocr Rev
, vol.24
, pp. 218-235
-
-
Canalis, E.1
Economides, A.N.2
Gazzerro, E.3
-
25
-
-
0031608330
-
The bone morphogenetic protein family: multifunctional cellular regulators in the embryo and adult
-
Wozney JM. The bone morphogenetic protein family: multifunctional cellular regulators in the embryo and adult. Eur J Oral Sci. 1998; 106:160-166.
-
(1998)
Eur J Oral Sci
, vol.106
, pp. 160-166
-
-
Wozney, J.M.1
-
26
-
-
24644507896
-
The disparate role of BMP in stem cell biology
-
Varga AC, Wrana JL. The disparate role of BMP in stem cell biology. Oncogene. 2005; 24:5713-5721.
-
(2005)
Oncogene
, vol.24
, pp. 5713-5721
-
-
Varga, A.C.1
Wrana, J.L.2
-
27
-
-
6944224156
-
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling
-
He XC, Zhang J, Tong WG, Tawfik O, Ross J, Scoville DH, Tian Q, Zeng X, He X, Wiedemann LM, Mishina Y, Li L. BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling. Nat Genet. 2004; 36:1117-1121.
-
(2004)
Nat Genet
, vol.36
, pp. 1117-1121
-
-
He, X.C.1
Zhang, J.2
Tong, W.G.3
Tawfik, O.4
Ross, J.5
Scoville, D.H.6
Tian, Q.7
Zeng, X.8
He, X.9
Wiedemann, L.M.10
Mishina, Y.11
Li, L.12
-
28
-
-
0036399170
-
Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulators
-
Balemans W, Van Hul W. Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulators. Dev Biol. 2002; 250:231-250.
-
(2002)
Dev Biol
, vol.250
, pp. 231-250
-
-
Balemans, W.1
Van Hul, W.2
-
29
-
-
0037733130
-
Skeletal overexpression of noggin results in osteopenia and reduced bone formation
-
Devlin RD, Du Z, Pereira RC, Kimble RB, Economides AN, Jorgetti V, Canalis E. Skeletal overexpression of noggin results in osteopenia and reduced bone formation. Endocrinology. 2003; 144:1972-1978.
-
(2003)
Endocrinology
, vol.144
, pp. 1972-1978
-
-
Devlin, R.D.1
Du, Z.2
Pereira, R.C.3
Kimble, R.B.4
Economides, A.N.5
Jorgetti, V.6
Canalis, E.7
-
30
-
-
84862298985
-
Identification of NOG as a specific breast cancer bone metastasis-supporting gene
-
Tarragona M, Pavlovic M, Arnal-Estape A, Urosevic J, Morales M, Guiu M, Planet E, Gonzalez-Suarez E, Gomis RR. Identification of NOG as a specific breast cancer bone metastasis-supporting gene. J Biol Chem. 2012; 287:21346-21355.
-
(2012)
J Biol Chem
, vol.287
, pp. 21346-21355
-
-
Tarragona, M.1
Pavlovic, M.2
Arnal-Estape, A.3
Urosevic, J.4
Morales, M.5
Guiu, M.6
Planet, E.7
Gonzalez-Suarez, E.8
Gomis, R.R.9
-
31
-
-
84891622107
-
Biological subtypes of breast cancer: current concepts and implications for recurrence patterns
-
Cadoo KA, Fornier MN, Morris PG. Biological subtypes of breast cancer: current concepts and implications for recurrence patterns. Q J Nucl Med Mol Imaging. 2013; 57:312-321.
-
(2013)
Q J Nucl Med Mol Imaging
, vol.57
, pp. 312-321
-
-
Cadoo, K.A.1
Fornier, M.N.2
Morris, P.G.3
-
32
-
-
67649311599
-
Latent bone metastasis in breast cancer tied to Src-dependent survival signals
-
Zhang XH, Wang Q, Gerald W, Hudis CA, Norton L, Smid M, Foekens JA, Massague J. Latent bone metastasis in breast cancer tied to Src-dependent survival signals. Cancer Cell. 2009; 16:67-78.
-
(2009)
Cancer Cell
, vol.16
, pp. 67-78
-
-
Zhang, X.H.1
Wang, Q.2
Gerald, W.3
Hudis, C.A.4
Norton, L.5
Smid, M.6
Foekens, J.A.7
Massague, J.8
-
33
-
-
33744813556
-
Genes associated with breast cancer metastatic to bone
-
Smid M, Wang Y, Klijn JG, Sieuwerts AM, Zhang Y, Atkins D, Martens JW, Foekens JA. Genes associated with breast cancer metastatic to bone. J Clin Oncol. 2006; 24:2261-2267.
-
(2006)
J Clin Oncol
, vol.24
, pp. 2261-2267
-
-
Smid, M.1
Wang, Y.2
Klijn, J.G.3
Sieuwerts, A.M.4
Zhang, Y.5
Atkins, D.6
Martens, J.W.7
Foekens, J.A.8
-
34
-
-
84869160169
-
Epithelialto- mesenchymal transition leads to docetaxel resistance in prostate cancer and is mediated by reduced expression of miR-200c and miR-205
-
Puhr M, Hoefer J, Schafer G, Erb HH, Oh SJ, Klocker H, Heidegger I, Neuwirt H, Culig Z. Epithelialto- mesenchymal transition leads to docetaxel resistance in prostate cancer and is mediated by reduced expression of miR-200c and miR-205. Am J Pathol. 2012; 181:2188-2201.
-
(2012)
Am J Pathol
, vol.181
, pp. 2188-2201
-
-
Puhr, M.1
Hoefer, J.2
Schafer, G.3
Erb, H.H.4
Oh, S.J.5
Klocker, H.6
Heidegger, I.7
Neuwirt, H.8
Culig, Z.9
-
35
-
-
84930181902
-
ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat.
-
Meidhof S, Brabletz S, Lehmann W, Preca BT, Mock K, Ruh M, Schuler J, Berthold M, Weber A, Burk U, Lubbert M, Puhr M, Culig Z, et al. ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat. EMBO Mol Med. 2015; doi 10.15252/emmm.201404396.
-
(2015)
EMBO Mol Med.
-
-
Meidhof, S.1
Brabletz, S.2
Lehmann, W.3
Preca, B.T.4
Mock, K.5
Ruh, M.6
Schuler, J.7
Berthold, M.8
Weber, A.9
Burk, U.10
Lubbert, M.11
Puhr, M.12
Culig, Z.13
-
36
-
-
84879564968
-
Zeb1 regulates E-cadherin and Epcam expression to control cell behavior in early zebrafish development.
-
Vannier C, Mock K, Brabletz T, Driever W. Zeb1 regulates E-cadherin and Epcam expression to control cell behavior in early zebrafish development. J Biol Chem. 288:18643-18659.
-
J Biol Chem.
, vol.288
, pp. 18643-18659
-
-
Vannier, C.1
Mock, K.2
Brabletz, T.3
Driever, W.4
-
37
-
-
77956230322
-
The ZEB/miR-200 feedback loop- a motor of cellular plasticity in development and cancer?
-
Brabletz S, Brabletz T. The ZEB/miR-200 feedback loop- a motor of cellular plasticity in development and cancer? EMBO Rep. 2010; 11:670-677.
-
(2010)
EMBO Rep.
, vol.11
, pp. 670-677
-
-
Brabletz, S.1
Brabletz, T.2
-
38
-
-
33744727364
-
BMP and BMP inhibitors in bone
-
Rosen V. BMP and BMP inhibitors in bone. Ann N Y Acad Sci. 2006; 1068:19-25.
-
(2006)
Ann N Y Acad Sci
, vol.1068
, pp. 19-25
-
-
Rosen, V.1
-
39
-
-
79251571488
-
The role of the BMP signaling antagonist noggin in the development of prostate cancer osteolytic bone metastasis
-
Secondini C, Wetterwald A, Schwaninger R, Thalmann GN, Cecchini MG. The role of the BMP signaling antagonist noggin in the development of prostate cancer osteolytic bone metastasis. PLoS One. 2011; 6:e16078.
-
(2011)
PLoS One
, vol.6
, pp. e16078
-
-
Secondini, C.1
Wetterwald, A.2
Schwaninger, R.3
Thalmann, G.N.4
Cecchini, M.G.5
-
40
-
-
34848868159
-
Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors
-
Kosinski C, Li VS, Chan AS, Zhang J, Ho C, Tsui WY, Chan TL, Mifflin RC, Powell DW, Yuen ST, Leung SY, Chen X. Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors. Proc Natl Acad Sci U S A. 2007; 104:15418-15423.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 15418-15423
-
-
Kosinski, C.1
Li, V.S.2
Chan, A.S.3
Zhang, J.4
Ho, C.5
Tsui, W.Y.6
Chan, T.L.7
Mifflin, R.C.8
Powell, D.W.9
Yuen, S.T.10
Leung, S.Y.11
Chen, X.12
-
41
-
-
85017733052
-
Bone morphogenetic protein antagonist gremlin-1 regulates colon cancer progression.
-
Karagiannis GS, Musrap N, Saraon P, Treacy A, Schaeffer DF, Kirsch R, Riddell RH, Diamandis EP. Bone morphogenetic protein antagonist gremlin-1 regulates colon cancer progression. Biol Chem.
-
Biol Chem.
-
-
Karagiannis, G.S.1
Musrap, N.2
Saraon, P.3
Treacy, A.4
Schaeffer, D.F.5
Kirsch, R.6
Riddell, R.H.7
Diamandis, E.P.8
-
42
-
-
0031594268
-
DeltaEF1, a zinc finger and homeodomain transcription factor, is required for skeleton patterning in multiple lineages
-
Takagi T, Moribe H, Kondoh H, Higashi Y. DeltaEF1, a zinc finger and homeodomain transcription factor, is required for skeleton patterning in multiple lineages. Development. 1998; 125:21-31.
-
(1998)
Development
, vol.125
, pp. 21-31
-
-
Takagi, T.1
Moribe, H.2
Kondoh, H.3
Higashi, Y.4
-
43
-
-
34548695219
-
deltaEF1 represses BMP-2-induced differentiation of C2C12 myoblasts into the osteoblast lineage
-
Yang S, Zhao L, Yang J, Chai D, Zhang M, Zhang J, Ji X, Zhu T. deltaEF1 represses BMP-2-induced differentiation of C2C12 myoblasts into the osteoblast lineage. J Biomed Sci. 2007; 14:663-679.
-
(2007)
J Biomed Sci
, vol.14
, pp. 663-679
-
-
Yang, S.1
Zhao, L.2
Yang, J.3
Chai, D.4
Zhang, M.5
Zhang, J.6
Ji, X.7
Zhu, T.8
-
44
-
-
13444268127
-
Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors
-
Minn AJ, Kang Y, Serganova I, Gupta GP, Giri DD, Doubrovin M, Ponomarev V, Gerald WL, Blasberg R, Massague J. Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors. J Clin Invest. 2005; 115:44-55.
-
(2005)
J Clin Invest
, vol.115
, pp. 44-55
-
-
Minn, A.J.1
Kang, Y.2
Serganova, I.3
Gupta, G.P.4
Giri, D.D.5
Doubrovin, M.6
Ponomarev, V.7
Gerald, W.L.8
Blasberg, R.9
Massague, J.10
-
45
-
-
0033561535
-
Severe combined immunodeficient-hu model of human prostate cancer metastasis to human bone
-
Nemeth JA, Harb JF, Barroso U, Jr., He Z, Grignon DJ, Cher ML. Severe combined immunodeficient-hu model of human prostate cancer metastasis to human bone. Cancer Res. 1999; 59:1987-1993.
-
(1999)
Cancer Res
, vol.59
, pp. 1987-1993
-
-
Nemeth, J.A.1
Harb, J.F.2
Barroso, U.3
He, Z.4
Grignon, D.J.5
Cher, M.L.6
-
46
-
-
79751472667
-
Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells
-
Sethi N, Dai X, Winter CG, Kang Y. Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells. Cancer Cell. 2011; 19:192-205.
-
(2011)
Cancer Cell
, vol.19
, pp. 192-205
-
-
Sethi, N.1
Dai, X.2
Winter, C.G.3
Kang, Y.4
-
47
-
-
79951813950
-
The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells.
-
Brabletz S, Bajdak K, Meidhof S, Burk U, Niedermann G, Firat E, Wellner U, Dimmler A, Faller G, Schubert J, Brabletz T. The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. Embo J. 30:770-782.
-
Embo J.
, vol.30
, pp. 770-782
-
-
Brabletz, S.1
Bajdak, K.2
Meidhof, S.3
Burk, U.4
Niedermann, G.5
Firat, E.6
Wellner, U.7
Dimmler, A.8
Faller, G.9
Schubert, J.10
Brabletz, T.11
-
48
-
-
84918562001
-
miR-429 inhibits migration and invasion of breast cancer cells in vitro
-
Ye ZB, Ma G, Zhao YH, Xiao Y, Zhan Y, Jing C, Gao K, Liu ZH, Yu SJ. miR-429 inhibits migration and invasion of breast cancer cells in vitro. Int J Oncol. 2015; 46:531-538.
-
(2015)
Int J Oncol
, vol.46
, pp. 531-538
-
-
Ye, Z.B.1
Ma, G.2
Zhao, Y.H.3
Xiao, Y.4
Zhan, Y.5
Jing, C.6
Gao, K.7
Liu, Z.H.8
Yu, S.J.9
-
49
-
-
84880934564
-
The Pitx2:miR- 200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation
-
Cao H, Jheon A, Li X, Sun Z, Wang J, Florez S, Zhang Z, McManus MT, Klein OD, Amendt BA. The Pitx2:miR- 200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation. Development. 140:3348-3359.
-
Development.
, vol.140
, pp. 3348-3359
-
-
Cao, H.1
Jheon, A.2
Li, X.3
Sun, Z.4
Wang, J.5
Florez, S.6
Zhang, Z.7
McManus, M.T.8
Klein, O.D.9
Amendt, B.A.10
-
50
-
-
0038324071
-
Opposing functions of ZEB proteins in the regulation of the TGFbeta/BMP signaling pathway
-
Postigo AA. Opposing functions of ZEB proteins in the regulation of the TGFbeta/BMP signaling pathway. EMBO J. 2003; 22:2443-2452.
-
(2003)
EMBO J
, vol.22
, pp. 2443-2452
-
-
Postigo, A.A.1
-
51
-
-
79960119681
-
A novel MCF-10A line allowing conditional oncogene expression in 3D culture
-
Herr R, Wohrle FU, Danke C, Berens C, Brummer T. A novel MCF-10A line allowing conditional oncogene expression in 3D culture. Cell Commun Signal. 2011; 9:17.
-
(2011)
Cell Commun Signal
, vol.9
, pp. 17
-
-
Herr, R.1
Wohrle, F.U.2
Danke, C.3
Berens, C.4
Brummer, T.5
-
52
-
-
39049160267
-
The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer
-
Spaderna S, Schmalhofer O, Wahlbuhl M, Dimmler A, Bauer K, Sultan A, Hlubek F, Jung A, Strand D, Eger A, Kirchner T, Behrens J, Brabletz T. The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer. Cancer Res. 2008; 68:537-544.
-
(2008)
Cancer Res
, vol.68
, pp. 537-544
-
-
Spaderna, S.1
Schmalhofer, O.2
Wahlbuhl, M.3
Dimmler, A.4
Bauer, K.5
Sultan, A.6
Hlubek, F.7
Jung, A.8
Strand, D.9
Eger, A.10
Kirchner, T.11
Behrens, J.12
Brabletz, T.13
-
53
-
-
34250679405
-
Specificity, duplex degradation and subcellular localization of antagomirs
-
Krutzfeldt J, Kuwajima S, Braich R, Rajeev KG, Pena J, Tuschl T, Manoharan M, Stoffel M. Specificity, duplex degradation and subcellular localization of antagomirs. Nucleic Acids Res. 2007; 35:2885-2892.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 2885-2892
-
-
Krutzfeldt, J.1
Kuwajima, S.2
Braich, R.3
Rajeev, K.G.4
Pena, J.5
Tuschl, T.6
Manoharan, M.7
Stoffel, M.8
-
54
-
-
84861885576
-
Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling
-
Roring M, Herr R, Fiala GJ, Heilmann K, Braun S, Eisenhardt AE, Halbach S, Capper D, von Deimling A, Schamel WW, Saunders DN, Brummer T. Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling. EMBO J. 2012; 31:2629-2647.
-
(2012)
EMBO J
, vol.31
, pp. 2629-2647
-
-
Roring, M.1
Herr, R.2
Fiala, G.J.3
Heilmann, K.4
Braun, S.5
Eisenhardt, A.E.6
Halbach, S.7
Capper, D.8
von Deimling, A.9
Schamel, W.W.10
Saunders, D.N.11
Brummer, T.12
-
55
-
-
27344435774
-
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES, Mesirov JP. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A. 2005; 102:15545-15550.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
Mukherjee, S.4
Ebert, B.L.5
Gillette, M.A.6
Paulovich, A.7
Pomeroy, S.L.8
Golub, T.R.9
Lander, E.S.10
Mesirov, J.P.11
-
56
-
-
0038054341
-
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstrale M, Laurila E, Houstis N, Daly MJ, Patterson N, et al. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet. 2003; 34:267-273.
-
(2003)
Nat Genet
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.F.3
Subramanian, A.4
Sihag, S.5
Lehar, J.6
Puigserver, P.7
Carlsson, E.8
Ridderstrale, M.9
Laurila, E.10
Houstis, N.11
Daly, M.J.12
Patterson, N.13
|