Genetic variation in TLR10, an inhibitory toll-like receptor, influences susceptibility to complicated skin and skin structure infections

Journal of Infectious Diseases

Volumn 212, Issue 9, 2015, Pages 1491-1499

  Stappers, Mark H T ^a,b,d   Oosting, Marije ^a   Ioana, Mihai ^a   Reimnitz, Peter ^e   Mouton, Johan W ^a,b,c   Netea, Mihai G ^a   Gyssens, Inge C ^a,b,d   Joosten, Leo A B ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b CANISIUS WILHELMINA HOSPITAL   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d HASSELT UNIVERSITY   (Belgium)

^e BAYER PHARMA AG   (Germany)

Author keywords

acute bacterial skin and skin structure infections; immunity, innate; polymorphism, single nucleotide; receptors, pattern recognition; Toll like receptor 10

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN 8; TOLL LIKE RECEPTOR 10; TLR10 PROTEIN, HUMAN;

ALLELE; ARTICLE; COMPLICATED SKIN AND SKIN STRUCTURE INFECTION; CONTROLLED STUDY; CYTOKINE RELEASE; EMBRYO; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC CORRELATION; GENETIC VARIABILITY; GENOTYPE; HEK293 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; INFECTION SENSITIVITY; INNATE IMMUNITY; MAJOR CLINICAL STUDY; MULTICENTER STUDY (TOPIC); PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SINGLE NUCLEOTIDE POLYMORPHISM; SKIN INFECTION; TLR10 GENE; BACTEROIDES FRAGILIS; CASE CONTROL STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; GENETIC PREDISPOSITION; GENETICS; GENOTYPING TECHNIQUE; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MISSENSE MUTATION; MONONUCLEAR CELL; PATHOLOGY; SECRETION (PROCESS); SKIN; SKIN DISEASE; STAPHYLOCOCCUS AUREUS; STATISTICAL MODEL;

ALLELES; BACTEROIDES FRAGILIS; CASE-CONTROL STUDIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GENOTYPING TECHNIQUES; HEK293 CELLS; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; LOGISTIC MODELS; MUTATION, MISSENSE; POLYMORPHISM, SINGLE NUCLEOTIDE; SKIN; SKIN DISEASES; STAPHYLOCOCCUS AUREUS; TOLL-LIKE RECEPTOR 10;

EID: 84930997325     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiv229     Document Type: Article

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