An ace up their sleeve: A transcriptomic approach exposes the AceI efflux protein of Acinetobacter baumannii and reveals the drug efflux potential hidden in many microbial pathogens

Frontiers in Microbiology

Volumn 6, Issue APR, 2015, Pages

  Hassan, Karl A ^a   Elbourne, Liam D H ^a   Li, Liping ^a   Gamage, Hasinika K A H ^a   Liu, Qi ^a   Jackson, Scott M ^b,d   Sharples, David ^b   Kolstø, Anne Brit ^c   Henderson, Peter J F ^b   Paulsen, Ian T ^a  

^a MACQUARIE UNIVERSITY   (Australia)

^b UNIVERSITY OF LEEDS   (United Kingdom)

^c UNIVERSITY OF OSLO   (Norway)

^d ETH ZURICH   (Switzerland)

Author keywords

Adaptive resistance; Bacterial drug resistance transcriptomics; Bacterial transmembrane pair; Multidrug efflux systems

Indexed keywords

ACINETOBACTER CHLORHEXIDINE EFFLUX PROTEIN; ACRIFLAVINE; BENZALKONIUM; CHLORHEXIDINE; DEQUALINIUM; LYSINE REGULATOR; PROFLAVINE; PROTEIN; PROTEOBACTERIAL ANTIMICROBIAL COMPOUND EFFLUX FAMILY OF TRANSPORT PROTEIN; QACR PROTEIN; REGULATOR PROTEIN; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ACINETOBACTER BAUMANNII; ACINETOBACTER BAYLYI; ACQUIRED RESISTANCE; ADAPTIVE RESISTANCE; ANTIBIOTIC RESISTANCE; ARTICLE; BIOFILM; BURKHOLDERIA CENOCEPACIA; CELL ADHESION; CELL INVASION; DRUG TRANSPORT; GENE EXPRESSION; GENOME; HUMAN; INTRINSIC RESISTANCE; PSEUDOMONAS AERUGINOSA; REAL TIME POLYMERASE CHAIN REACTION; STAPHYLOCOCCUS AUREUS; TRANSCRIPTION INITIATION; VEILLONELLA PARVULA; VIBRIO PARAHAEMOLYTICUS;

ACINETOBACTER; ACINETOBACTER BAUMANNII; BACTERIA (MICROORGANISMS); PROTEOBACTERIA;

EID: 84930946138     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2015.00333     Document Type: Article

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