-
1
-
-
84878141871
-
The TLR4 antagonist Eritoran protects mice from lethal influenza infection
-
Shirey, K. A. et al. The TLR4 antagonist Eritoran protects mice from lethal influenza infection. Nature 497, 498-502.
-
Nature
, vol.497
, pp. 498-502
-
-
Shirey, K.A.1
-
2
-
-
0037425564
-
Mortality associated with influenza and respiratory syncytial virus in the United States
-
Thompson, W. W. et al. Mortality associated with influenza and respiratory syncytial virus in the United States. Jama 289, 179-186 (2003).
-
(2003)
Jama
, vol.289
, pp. 179-186
-
-
Thompson, W.W.1
-
3
-
-
41749124757
-
The pathology of influenza virus infections
-
Taubenberger, J. K. & Morens, D. M. The pathology of influenza virus infections. Annu Rev Pathol 3, 499-522 (2008).
-
(2008)
Annu Rev Pathol
, vol.3
, pp. 499-522
-
-
Taubenberger, J.K.1
Morens, D.M.2
-
4
-
-
38949197905
-
Antiviral therapy and outcomes of influenza requiring hospitalization in Ontario, Canada
-
McGeer, A. et al. Antiviral therapy and outcomes of influenza requiring hospitalization in Ontario, Canada. Clin Infect Dis 45, 1568-1575 (2007).
-
(2007)
Clin Infect Dis
, vol.45
, pp. 1568-1575
-
-
McGeer, A.1
-
5
-
-
84942782497
-
Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children
-
Jefferson, T. et al. Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children. Cochrane Database Syst Rev 4, CD008965.
-
Cochrane Database Syst Rev
, vol.4
, pp. CD008965
-
-
Jefferson, T.1
-
6
-
-
84898836342
-
The neuraminidase inhibitor oseltamivir is effective against A/Anhui/1/2013 (H7N9) influenza virus in a mouse model of acute respiratory distress syndrome
-
Baranovich, T. et al. The neuraminidase inhibitor oseltamivir is effective against A/Anhui/1/2013 (H7N9) influenza virus in a mouse model of acute respiratory distress syndrome. J Infect Dis 209, 1343-1353.
-
J Infect Dis
, vol.209
, pp. 1343-1353
-
-
Baranovich, T.1
-
7
-
-
76749102845
-
Effects of oseltamivir treatment on duration of clinical illness and viral shedding and household transmission of influenza virus
-
Ng, S. et al. Effects of oseltamivir treatment on duration of clinical illness and viral shedding and household transmission of influenza virus. Clin Infect Dis 50, 707-714 (2010).
-
(2010)
Clin Infect Dis
, vol.50
, pp. 707-714
-
-
Ng, S.1
-
8
-
-
84896992391
-
Antiviral susceptibility of variant influenza A(H3N2)v viruses isolated in the United States from 2011 to 2013
-
Sleeman, K. et al. Antiviral susceptibility of variant influenza A(H3N2)v viruses isolated in the United States from 2011 to 2013. Antimicrob Agents Chemother 58, 2045-2051 (2014).
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 2045-2051
-
-
Sleeman, K.1
-
9
-
-
84870285674
-
The ongoing battle against influenza: Drug-resistant influenza viruses: Why fitness matters
-
Kelso, A. & Hurt, A. C. The ongoing battle against influenza: Drug-resistant influenza viruses: why fitness matters. Nat Med 18, 1470-1471 (2012).
-
(2012)
Nat Med
, vol.18
, pp. 1470-1471
-
-
Kelso, A.1
Hurt, A.C.2
-
10
-
-
70449659985
-
Critically Ill patients with 2009 influenza A(H1N1) in Mexico
-
Dominguez-Cherit, G. et al. Critically Ill patients with 2009 influenza A(H1N1) in Mexico. Jama 302, 1880-1887 (2009).
-
(2009)
Jama
, vol.302
, pp. 1880-1887
-
-
Dominguez-Cherit, G.1
-
11
-
-
0000232306
-
Studies on influenza in the pandemic of 1957-1958. II. Pulmonary complications of influenza
-
Louria, D. B., Blumenfeld, H. L., Ellis, J. T., Kilbourne, E. D. & Rogers, D. E. Studies on influenza in the pandemic of 1957-1958. II. Pulmonary complications of influenza. J Clin Invest 38, 213-265 (1959).
-
(1959)
J Clin Invest
, vol.38
, pp. 213-265
-
-
Louria, D.B.1
Blumenfeld, H.L.2
Ellis, J.T.3
Kilbourne, E.D.4
Rogers, D.E.5
-
12
-
-
0034909013
-
Ventilator-induced lung injury and recommendations for mechanical ventilation of patients with ARDS
-
Lee, W. L. & Slutsky, A. S. Ventilator-induced lung injury and recommendations for mechanical ventilation of patients with ARDS. Semin Respir Crit Care Med 22, 269-280 (2001).
-
(2001)
Semin Respir Crit Care Med
, vol.22
, pp. 269-280
-
-
Lee, W.L.1
Slutsky, A.S.2
-
13
-
-
84864742993
-
The acute respiratory distress syndrome
-
Matthay, M. A., Ware, L. B. & Zimmerman, G. A. The acute respiratory distress syndrome. J Clin Invest 122, 2731-2740 (2012).
-
(2012)
J Clin Invest
, vol.122
, pp. 2731-2740
-
-
Matthay, M.A.1
Ware, L.B.2
Zimmerman, G.A.3
-
14
-
-
77951836880
-
Targeting Robo4-dependent slit signaling to survive the cytokine storm in sepsis and influenza
-
London, N. R. et al. Targeting Robo4-dependent slit signaling to survive the cytokine storm in sepsis and influenza. Sci Transl Med 2, 23ra19 (2010).
-
(2010)
Sci Transl Med
, vol.2
, pp. 23ra19
-
-
London, N.R.1
-
15
-
-
80052510176
-
Excessive neutrophils and neutrophil extracellular traps contribute to acute lung injury of influenza pneumonitis
-
Narasaraju, T. et al. Excessive neutrophils and neutrophil extracellular traps contribute to acute lung injury of influenza pneumonitis. Am J Pathol 179, 199-210 (2011).
-
(2011)
Am J Pathol
, vol.179
, pp. 199-210
-
-
Narasaraju, T.1
-
16
-
-
79958231061
-
Effects of a synthetic PEG-ylated Tie-2 agonist peptide on endotoxemic lung injury and mortality
-
David, S. et al. Effects of a synthetic PEG-ylated Tie-2 agonist peptide on endotoxemic lung injury and mortality. Am J Physiol Lung Cell Mol Physiol 300, L851-862 (2011).
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, vol.300
, pp. L851-862
-
-
David, S.1
-
17
-
-
79952634012
-
The role of neutrophils during mild and severe influenza virus infections of mice
-
Tate, M. D. et al. The role of neutrophils during mild and severe influenza virus infections of mice. PLoS One 6, e17618 (2011).
-
(2011)
PLoS One
, vol.6
-
-
Tate, M.D.1
-
18
-
-
84856078603
-
Efficacy of combined therapy with amantadine, oseltamivir, and ribavirin in vivo against susceptible and amantadine-resistant influenza A viruses
-
Nguyen, J. T. et al. Efficacy of combined therapy with amantadine, oseltamivir, and ribavirin in vivo against susceptible and amantadine-resistant influenza A viruses. PLoS One 7, e31006 (2012).
-
(2012)
PLoS One
, vol.7
-
-
Nguyen, J.T.1
-
19
-
-
0030460424
-
Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning
-
Davis, S. et al. Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning. Cell 87, 1161-1169 (1996).
-
(1996)
Cell
, vol.87
, pp. 1161-1169
-
-
Davis, S.1
-
20
-
-
70350503289
-
The angiopietin-1-Tie2 pathway prevents rather than promotes pulmonary arterial hypertension in transgenic mice
-
Kugathasan, L. et al. The angiopietin-1-Tie2 pathway prevents rather than promotes pulmonary arterial hypertension in transgenic mice. J Exp Med 206, 2221-2234 (2009).
-
(2009)
J Exp Med
, vol.206
, pp. 2221-2234
-
-
Kugathasan, L.1
-
21
-
-
0030764063
-
Tie2 expression and phosphorylation in angiogenic and quiescent adult tissues
-
Wong, A. L. et al. Tie2 expression and phosphorylation in angiogenic and quiescent adult tissues. Circ Res 81, 567-574 (1997).
-
(1997)
Circ Res
, vol.81
, pp. 567-574
-
-
Wong, A.L.1
-
22
-
-
3042702886
-
Akt is a major angiogenic mediator downstream of the Ang1/Tie2 signaling pathway
-
DeBusk, L. M., Hallahan, D. E. & Lin, P. C. Akt is a major angiogenic mediator downstream of the Ang1/Tie2 signaling pathway. Exp Cell Res 298, 167-177 (2004).
-
(2004)
Exp Cell Res
, vol.298
, pp. 167-177
-
-
Debusk, L.M.1
Hallahan, D.E.2
Lin, P.C.3
-
23
-
-
78751692321
-
Endothelial LSP1 is involved in endothelial dome formation, minimizing vascular permeability changes during neutrophil transmigration in vivo
-
Petri, B. et al. Endothelial LSP1 is involved in endothelial dome formation, minimizing vascular permeability changes during neutrophil transmigration in vivo. Blood 117, 942-952 (2011).
-
(2011)
Blood
, vol.117
, pp. 942-952
-
-
Petri, B.1
-
24
-
-
84875433659
-
Mending leaky blood vessels: The angiopoietin-Tie2 pathway in sepsis
-
David, S., Kumpers, P., van Slyke, P. & Parikh, S. M. Mending leaky blood vessels: the angiopoietin-Tie2 pathway in sepsis. J Pharmacol Exp Ther 345, 2-6 (2013).
-
(2013)
J Pharmacol Exp Ther
, vol.345
, pp. 2-6
-
-
David, S.1
Kumpers, P.2
Van Slyke, P.3
Parikh, S.M.4
-
25
-
-
0034036689
-
Angiopoietin-1 protects the adult vasculature against plasma leakage
-
Thurston, G. et al. Angiopoietin-1 protects the adult vasculature against plasma leakage. Nat Med 6, 460-463 (2000).
-
(2000)
Nat Med
, vol.6
, pp. 460-463
-
-
Thurston, G.1
-
26
-
-
11244337801
-
Protective role of angiopoietin-1 in endotoxic shock
-
Witzenbichler, B., Westermann, D., Knueppel, S., Schultheiss, H. P. & Tschope, C. Protective role of angiopoietin-1 in endotoxic shock. Circulation 111, 97-105 (2005).
-
(2005)
Circulation
, vol.111
, pp. 97-105
-
-
Witzenbichler, B.1
Westermann, D.2
Knueppel, S.3
Schultheiss, H.P.4
Tschope, C.5
-
27
-
-
84871719489
-
Orchestral actions of angiopoietin-1 in vascular regeneration
-
Koh, G. Y. Orchestral actions of angiopoietin-1 in vascular regeneration. Trends Mol Med 19, 31-39 (2013).
-
(2013)
Trends Mol Med
, vol.19
, pp. 31-39
-
-
Koh, G.Y.1
-
28
-
-
66249112824
-
Acceleration of diabetic wound healing by an angiopoietin peptide mimetic
-
Van Slyke, P. et al. Acceleration of diabetic wound healing by an angiopoietin peptide mimetic. Tissue engineering. Part A 15, 1269-1280 (2009).
-
(2009)
Tissue Engineering. Part A
, vol.15
, pp. 1269-1280
-
-
Van Slyke, P.1
-
29
-
-
10944262091
-
A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor
-
Tournaire, R. et al. A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor. EMBO Rep 5, 262-267 (2004).
-
(2004)
EMBO Rep
, vol.5
, pp. 262-267
-
-
Tournaire, R.1
-
30
-
-
33646780950
-
Signaling and functions of angiopoietin-1 in vascular protection
-
Brindle, N. P., Saharinen, P. & Alitalo, K. Signaling and functions of angiopoietin-1 in vascular protection. Circ Res 98, 1014-1023 (2006).
-
(2006)
Circ Res
, vol.98
, pp. 1014-1023
-
-
Brindle, N.P.1
Saharinen, P.2
Alitalo, K.3
-
31
-
-
0034737422
-
Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway
-
Papapetropoulos, A. et al. Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway. J Biol Chem 275, 9102-9105 (2000).
-
(2000)
J Biol Chem
, vol.275
, pp. 9102-9105
-
-
Papapetropoulos, A.1
-
32
-
-
33645355399
-
Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans
-
Parikh, S. M. et al. Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans. PLoS Med 3, e46 (2006).
-
(2006)
PLoS Med
, vol.3
, pp. e46
-
-
Parikh, S.M.1
-
33
-
-
84877788239
-
VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation
-
Hayashi, M. et al. VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation. Nat Commun 4, 1672 (2013).
-
(2013)
Nat Commun
, vol.4
, pp. 1672
-
-
Hayashi, M.1
-
34
-
-
51849103407
-
Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: Implications for pandemic influenza preparedness
-
Morens, D. M., Taubenberger, J. K. & Fauci, A. S. Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: implications for pandemic influenza preparedness. J Infect Dis 198, 962-970 (2008).
-
(2008)
J Infect Dis
, vol.198
, pp. 962-970
-
-
Morens, D.M.1
Taubenberger, J.K.2
Fauci, A.S.3
-
35
-
-
84355162830
-
Do viral infections mimic bacterial sepsis? The role of microvascular permeability: A review of mechanisms and methods
-
Steinberg, B. E., Goldenberg, N. M. & Lee, W. L. Do viral infections mimic bacterial sepsis? The role of microvascular permeability: A review of mechanisms and methods. Antiviral Res 93, 2-15 (2012).
-
(2012)
Antiviral Res
, vol.93
, pp. 2-15
-
-
Steinberg, B.E.1
Goldenberg, N.M.2
Lee, W.L.3
-
36
-
-
34748893547
-
A mouse model for studying the interaction of bisdioxopiperazines with topoisomerase IIalpha in vivo
-
Grauslund, M. et al. A mouse model for studying the interaction of bisdioxopiperazines with topoisomerase IIalpha in vivo. Mol Pharmacol 72, 1003-1014 (2007).
-
(2007)
Mol Pharmacol
, vol.72
, pp. 1003-1014
-
-
Grauslund, M.1
-
37
-
-
84880666503
-
Influenza: Propagation, quantification, and storage
-
Chapter 15, Unit 15G 11
-
Szretter, K. J., Balish, A. L. & Katz, J. M. Influenza: propagation, quantification, and storage. Curr Protoc Microbiol Chapter 15, Unit 15G 11 (2006).
-
(2006)
Curr Protoc Microbiol
-
-
Szretter, K.J.1
Balish, A.L.2
Katz, J.M.3
-
38
-
-
84881562206
-
Mesenchymal stromal (stem) cell therapy fails to improve outcomes in experimental severe influenza
-
Darwish, I. et al. Mesenchymal stromal (stem) cell therapy fails to improve outcomes in experimental severe influenza. PLoS One 8, e71761 (2013).
-
(2013)
PLoS One
, vol.8
-
-
Darwish, I.1
-
39
-
-
84868122300
-
Influenza infects lung microvascular endothelium leading to microvascular leak: Role of apoptosis and claudin-5
-
Armstrong, S. M. et al. Influenza infects lung microvascular endothelium leading to microvascular leak: role of apoptosis and claudin-5. PLoS One 7, e47323 (2012).
-
(2012)
PLoS One
, vol.7
-
-
Armstrong, S.M.1
-
40
-
-
84898640616
-
Conditional cardiac overexpression of S100A6 attenuates myocyte hypertrophy and apoptosis following myocardial infarction
-
Tsoporis, J. T., Izhar, S., Desjardins, J. F., Leong-Poi, H. & Parker, T. G. Conditional cardiac overexpression of S100A6 attenuates myocyte hypertrophy and apoptosis following myocardial infarction. Curr Pharm Des 20, 1941-1949 (2014).
-
(2014)
Curr Pharm des
, vol.20
, pp. 1941-1949
-
-
Tsoporis, J.T.1
Izhar, S.2
Desjardins, J.F.3
Leong-Poi, H.4
Parker, T.G.5
-
41
-
-
79955487598
-
An official American Thoracic Society workshop report: Features and measurements of experimental acute lung injury in animals
-
Matute-Bello, G. et al. An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals. Am J Respir Cell Mol Biol 44, 725-738 (2011).
-
(2011)
Am J Respir Cell Mol Biol
, vol.44
, pp. 725-738
-
-
Matute-Bello, G.1
-
42
-
-
68549111147
-
The (Pro)renin receptor: Site-specific and functional linkage to the vacuolar H+ -ATPase in the kidney
-
Advani, A. et al. The (Pro)renin receptor: site-specific and functional linkage to the vacuolar H+ -ATPase in the kidney. Hypertension 54, 261-269 (2009).
-
(2009)
Hypertension
, vol.54
, pp. 261-269
-
-
Advani, A.1
-
44
-
-
84863127141
-
Co-regulation of transcellular and paracellular leak across microvascular endothelium by dynamin and Rac
-
Armstrong, S. M. et al. Co-regulation of transcellular and paracellular leak across microvascular endothelium by dynamin and Rac. Am J Pathol 180, 1308-1323 (2012).
-
(2012)
Am J Pathol
, vol.180
, pp. 1308-1323
-
-
Armstrong, S.M.1
|