Ventilator-induced lung injury and recommendations for mechanical ventilation of patients with ARDS

Seminars in Respiratory and Critical Care Medicine

Volumn 22, Issue 3, 2001, Pages 269-280

  Lee, W L ^a   Slutsky, A S ^a  

^a ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

Atelectasis; Barotrauma; Biotrauma; Pressure volume curve; Recruitment derecruitment; Ventilator induced lung injury; Volutrauma

Indexed keywords

ACUTE RESPIRATORY FAILURE; ADULT RESPIRATORY DISTRESS SYNDROME; ARTIFICIAL VENTILATION; HUMAN; LUNG COMPLICATION; LUNG EMPHYSEMA; LUNG INJURY; MULTIPLE ORGAN FAILURE; PNEUMOTHORAX; PRIORITY JOURNAL; RESUSCITATION; REVIEW; VENTILATOR;

EID: 0034909013     PISSN: 10693424     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2001-15784     Document Type: Review

References (66)

1. History of mechanical ventilation
2. Mechanical ventilation as a mediator of multisystem organ failure in acute respiratory distress syndrome
3. Ventilator-induced lung injury: Lessons from experimental studies
4. High inflation pressure pulmonary edema: Respective effects of high airway pressure, high tidal volume, and positive end-expiratory pressure
5. Chest wall restriction limits high airway pressure-induced lung injury in young rabbits
6. Lung overexpansion increases pulmonary microvascular protein permeability in young lambs
7. PEEP and low tidal volume ventilation reduce lung water in porcine pulmonary edema
8. Effect of end-expiratory airway pressure on accumulation of extravascular lung water
9. Role of tidal volume, FRC, and end-inspiratory volume in the development of pulmonary edema following mechanical ventilation
10. Effect of tidal volume and PEEP on rate of edema formation in in situ perfused canine lobes
11. Lung injury caused by mechanical ventilation
12. Stress distribution in lungs: A model of pulmonary elasticity
13. Titration of tidal volume and induced hypercapnia in acute respiratory distress syndrome
14. Beneficial effects of the "open lung approach" with low distending pressures in acure respiratory distress syndrome: A prospective randomised study on mechanical ventilation
15. Tidal ventilation at low airway pressures can augment lung injury
16. Effects of positive end-expiratory pressure on hyaline membrane formation in rabbit model of the neonatal respiratory distress syndrome
17. Surfactant dysfunction makes lungs vulnerable to repetitive collapse and reexpansion
18. Respiratory mechanics in ARDS: A siren for physicians?
19. Pressure-volume curves and compliance in acute lung injury: Evidence of recruitment above the lower inflection point
20. The open lung during small tidal volume ventilation: Concepts of recruitment and "optimal" positive end-expirator pressure
21. High-frequency ventilation for acute lung injury and ARDS
22. Lung volume maintenance prevents lung injury during high frequency oscillation in surfactant deficient rabbits
23. Volume recruitment maneuvers are less deleterious than persistent low lung volumes in the atelectasisprone rabbit lung during high-frequency oscillation
24. Effects of decreased respiratory frequency on ventilator-induced lung injury
25. The cardiovascular effects of mechanical ventilation and positive end-expiratory pressure
26. Effects of mean airway pressure and tidal excursion on lung injury induced by mechanical ventilation in an isolated perfused rabbit lung model
27. Mechanical ventilation-induced pulmonary edema: Interaction with previous lung alterations
28. Regional effects and mechanism of positive end-expiratory pressure in early adult respiratory distress syndrome
29. Healthy lungs tolerate repetitive collapse and reopening during short periods of mechanical ventilation
30. High lung volume increases stress failure in pulmonary capillaries
31. Ventilatory-induced injury: Barotrauma and biotrauma
32. Invited Review: Mechanisms of ventilator-induced lung injury: A perspective
33. Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model
34. Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: A randomised controlled trial
35. Causes of mortality in patients with the adult respiratory distress syndrome
36. Mechanical ventilation affects local and systemic cytokines in an animal model of acute respiratory distress syndrome
37. Hyperventilation induces release of cytokines from perfused mouse lung
38. Multiple system organ failure: Is mechanical ventilation a contributing factor?
39. Effect of mechanical ventilation strategy on dissemination of intratracheally instilled Escherichia coli in dogs
40. Lung overinflation without positive end-expiratory pressure promotes bacteremia after experimental Klebsiella pneumoniae inoculation
41. Adverse ventilatory strategy causes pulmonary-to-systemic translocation of endotoxin
42. Stretch induces cytokine release by alveolar epithelial cells in vitro
43. Gadolinium prevents high airway pressure-induced permeability increases in isolated rat lungs
44. Ventilator-associated lung injury decreases lung ability to clear edema in rats
45. +-ATPase activity
46. Temporary disruption of the plasma membrane is required for c-los expression in response to mechanical stress
47. Inhibitors of myosin light chain kinase and phosphodiesterase reduce ventilator-induced lung injury
48. Stretch-induced mitogen-activated protein kinase activation and interleukin-8 production in type II alveolar cells
49. An intracellular signaling pathway linking lipopolysaccharide stimulation to cellular responses of the human neutrophil: The p38 MAP kinase cascade and its functional significance
50. Hypercapnic acidosis may attenuate acute lung injury by inhibition of endogenous xanthine oxidase
51. Therapeutic hypercapnia reduces pulmonary and systemic injury following in vivo lung reperfusion
52. Hypercapnia induces injury to alveolar epithelial cells via a nitric oxide-dependent pathway
53. Histopathologic pulmonary changes from mechanical ventilation at high peak airway pressures
54. Evaluation of a ventilation strategy to prevent barotrauma in patients at high risk for acure respiratory distress syndrome
55. Prospective, randomised, controlled clinical trial comparing traditional versus reduced tidal volume ventilation in acute respiratory distress syndrome patients
56. Tidal volume reduction for prevention of ventilator-induced lung injury in acute respiratory distress syndrome
57. Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome
58. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome
59. Lung-protective ventilation in ARDS
60. Mechanical ventilation: Lessons from the ARDSNet trial
61. Evaluation of Lung Protective Ventilation Strategies in ARDS
62. Mechanical ventilation
63. Acute lung injury in the medical ICU: Comorbid conditions, age, etiology, and hospital outcome
64. Acute respiratory distress syndrome caused by pulmonary and extrapulmonary disease: Different syndromes?
65. Impairment of lung and chest wall mechanics in patients with acute respiratory distress syndrome: Role of abdominal distension