Minimum genome factories in schizosaccharomyces pombe

Microbial Production: From Genome Design to Cell Engineering

Volumn , Issue , 2013, Pages 17-24

  Kumagai, Hiromichi ^a   Sasaki, Mayumi ^a   Idiris, Alimjan ^a   Tohda, Hideki ^a  

^a ASAHI GLASS CO LTD   (Japan)

Author keywords

LATOUR method; Minimum genome factory; Protein expression system; Schizosaccharomyces pombe (S. pombe)

Indexed keywords

EID: 84930901426     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-4-431-54607-8_2     Document Type: Chapter

References (24)

1. Ara K, Ozaki K, Nakamura K et al (2007) Bacillus minimum genome factory: effective utilization of microbial genome information. Biotechnol Appl Biochem 46(pt 3):169-178
2. Baba T, Ara T, Hasegawa M et al (2006) Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol Syst Biol 2:20060008. doi: 2010.1038/msb4100050
3. Decottignies A, Sanchez-Perez I, Nurse P (2003) Schizosaccharomyces pombe essential genes: a pilot study. Genome Res 13(3):399-406
4. Fantes P, Nurse P (1977) Control of cell size at division in fi ssion yeast by a growth-modulated size control over nuclear division. Exp Cell Res 107(2):377-386
5. Fujio T (2007) Minimum genome factory: innovation in bioprocesses through genome science. Biotechnol Appl Biochem 46(pt 3):145-146
6. Giga-Hama Y, Tohda H, Takegawa K et al (2007) Schizosaccharomyces pombe minimum genome factory. Biotechnol Appl Biochem 46(Pt 3):147-155
7. Hirashima K, Iwaki T, Takegawa K et al (2006) A simple and effective chromosome modifi cation method for large-scale deletion of genome sequences and identifi cation of essential genes in fi ssion yeast. Nucleic Acids Res 34(2):e11. doi: 10.1093/nar/gnj1011
8. Idiris A, Tohda H, Bi KW et al (2006) Enhanced productivity of protease-sensitive heterologous proteins by disruption of multiple protease genes in the fi ssion yeast Schizosaccharomyces pombe. Appl Microbiol Biotechnol 73(2):404-420
9. Idiris A, Tohda H, Sasaki M et al (2009) Enhanced protein secretion from multiprotease-defi cient fi ssion yeast by modifi cation of its vacuolar protein sorting pathway. Appl Microbiol Biotechnol 85(3):667-677
10. Idiris A, Tohda H, Kumagai H et al (2010) Engineering of protein secretion in yeast: strategies and impact on protein production. Appl Microbiol Biotechnol 86(2):403-417
11. Kim DU, Hayles J, Kim D et al (2010) Analysis of a genome-wide set of gene deletions in the fi ssion yeast Schizosaccharomyces pombe. Nat Biotechnol 28(6):617-623
12. Kobayashi K, Ehrlich SD, Albertini A et al (2003) Essential Bacillus subtilis genes. Proc Natl Acad Sci USA 100(8):4678-4683
13. Manabe K, Kageyama Y, Morimoto T et al (2011) Combined effect of improved cell yield and increased specifi c productivity enhances recombinant enzyme production in genome-reduced Bacillus subtilis strain MGB874. Appl Environ Microbiol 77(23):8370-8381
14. Matsuo T, Otsubo Y, Urano J et al (2007) Loss of the TOR kinase Tor2 mimics nitrogen starvation and activates the sexual development pathway in fi ssion yeast. Mol Cell Biol 27(8):3154-3164
15. Medema MH, van Raaphorst R, Takano E et al (2012) Computational tools for the synthetic design of biochemical pathways. Nat Rev Microbiol 10(3):191-202
16. Mizoguchi H, Mori H, Fujio T (2007) Escherichia coli minimum genome factory. Biotechnol Appl Biochem 46(Pt 3):157-167
17. Mizoguchi H, Sawano Y, Kato J et al (2008) Superpositioning of deletions promotes growth of Escherichia coli with a reduced genome. DNA Res 15(5):277-284
18. Morimoto T, Kadoya R, Endo K et al (2008) Enhanced recombinant protein productivity by genome reduction in Bacillus subtilis. DNA Res 15(2):73-81
19. Moya A, Gil R, Latorre A et al (2009) Toward minimal bacterial cells: evolution vs. design. FEMS Microbiol Rev 33(1):225-235
20. Murakami K, Tao E, Ito Y et al (2007) Large scale deletions in the Saccharomyces cerevisiae genome create strains with altered regulation of carbon metabolism. Appl Microbiol Biotechnol 75(3):589-597
21. Posfai G, Plunkett G 3rd, Feher T et al (2006) Emergent properties of reduced-genome Escherichia coli. Science 312(5776):1044-1046
22. Sasaki M, Kumagai H, Takegawa K et al (2013) Characterization of genome-reduced fi ssion yeast strains. Nucleic Acids Res 41(10):5382-5399
23. Wood V, Gwilliam R, Rajandream MA et al (2002) The genome sequence of Schizosaccharomyces pombe. Nature (Lond) 415(6874):871-880
24. Zhao Y, Lieberman HB (1995) Schizosaccharomyces pombe : a model for molecular studies of eukaryotic genes. DNA Cell Biol 14(5):359-371