ABCF1 extrinsically regulates retinal pigment epithelial cell phagocytosis

Molecular Biology of the Cell

Volumn 26, Issue 12, 2015, Pages 2311-2320

  Guo, Feiye ^a   Ding, Ying ^a   Caberoy, Nora ^b   Alvarado, Gabriela ^a   Wang, Feng ^c   Chen, Rui ^c   Li, Wei ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NEVADA   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER F1; PHOSPHATIDYLSERINE; RHODOPSIN; UNCLASSIFIED DRUG; ABCF1 PROTEIN, HUMAN; LIGAND;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EXPLANT; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LIGAND BINDING; MICROGLIA; MOUSE; NERVE CELL; NONHUMAN; PHAGOCYTE; PHAGOCYTOSIS; PHAGOSOME; PHOTORECEPTOR INNER SEGMENT; PHOTORECEPTOR OUTER SEGMENT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; REGULATORY MECHANISM; RETINA; RETINA GANGLION CELL; RETINA INNER NUCLEAR LAYER; RETINA INNER PLEXIFORM LAYER; RETINA OUTER NUCLEAR LAYER; RETINA OUTER PLEXIFORM LAYER; RETINA PIGMENT CELL; SCREENING; ANIMAL; CELL CULTURE; CYTOLOGY; METABOLISM; PHYSIOLOGY; RETINAL PIGMENT EPITHELIUM;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CELLS, CULTURED; HUMANS; LIGANDS; MICE; PHAGOCYTOSIS; RETINAL PHOTORECEPTOR CELL OUTER SEGMENT; RETINAL PIGMENT EPITHELIUM;

EID: 84930900218     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E14-09-1343     Document Type: Article

References (37)

1. Amin AR, Islam A.B. (2014). Genomic analysis and differential expression of HMG and S100A family in human arthritis: upregulated expression of chemokines, IL-8 and nitric oxide by HMGB1. DNA Cell Biol 33, 550-565.
2. Arur S, Uche UE, Rezaul K, Fong M., Scranton V, Cowan AE, Mohler W, Han D.K. (2003). Annexin I is an endogenous ligand that mediates apoptotic cell engulfment. Dev Cell 4, 587-598.
3. Brown GC, Neher J.J. (2014). Microglial phagocytosis of live neurons. Nat Rev Neurosci 15, 209-216.
4. Caberoy NB, Alvarado G, Bigcas J.L., Li W. (2012a). Galectin-3 is a new MerTK-specific eat-me signal. J Cell Physiol 227, 401-407.
5. Caberoy NB, Alvarado G, Li W. (2012b). Tubby regulates microglial phagocytosis through MerTK. J Neuroimmunol 252, 40-48.
6. Caberoy NB, Li W. (2012). Unraveling the molecular mystery of retinal pigment epithelium phagocytosis. Adv Exp Med Biol 723, 693-699.
7. Caberoy NB, Maiguel D, Kim Y., Li W. (2010a). Identification of tubby and tubby-like protein 1 as eat-me signals by phage display. Exp Cell Res 316, 245-257.
8. Caberoy NB, Zhou Y, Jiang X., Alvarado G, Li W. (2010b). Ejficient identification of tubby-binding proteins by an improved system of T7 phage display. J Mol Recognit 23, 74-83.
9. Caberoy NB, Zhou Y, Li W. (2009). Can phage display be used as a tool to functionally identify endogenous eat-me signals in phagocytosis? J Biomol Screen 14, 653-661.
10. Caberoy NB, Zhou Y, Li W. (2010c). Tubby and tubby-like protein 1 are new MerTK ligands for phagocytosis. EMBO J 29, 3898-3910.
11. Deretic D (1998). Post-Golgi trajficking of rhodopsin in retinal photoreceptors. Eye (Lond) 12, 526-530.
12. Dowling JE, Sidman R.L. (1962). Inherited retinal dystrophy in the rat. J Cell Biol 14, 73-109.
13. Erwig L.P., Henson P.M. (2007). Immunological consequences of apoptotic cell phagocytosis. Am J Pathol 171, 2-8.
14. Gal A, Li Y, Thompson D.A., Weir J., Orth U, Jacobson SG, Apfelstedt-Sylla E, Vollrath D. (2000). Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa. Nat Genet 26, 270-271.
15. Hall MO, Obin MS, Heeb M.J., Burgess BL, Abrams T.A. (2005). Both protein S and Gas6 stimulate outer segment phagocytosis by cultured rat retinal pigment epithelial cells. Exp Eye Res 81, 581-591.
16. Hochreiter-Hufford A., Ravichandran K.S. (2013). Clearing the dead: apoptotic cell sensing, recognition, engulfment, and digestion. Cold Spring Harb Perspect Biol 5, a008748.
17. Jonsson T, Stefansson H, Steinberg S., Jonsdottir I, Jonsson PV, Snaedal J, Bjornsson S., Huttenlocher J, Levey AI, Lah J.J., et al. (2013). Variant of TREM2 associated with the risk of Alzheimer's disease. N Engl J Med 368, 107-116.
18. Katz ML, Robison WG Jr (1984). Age-related changes in the retinal pigment epithelium of pigmented rats. Exp Eye Res 38, 137-151.
19. Kevany BM, Palczewski K. (2010). Phagocytosis of retinal rod and cone photoreceptors. Physiology (Bethesda) 25, 8-15.
20. Kim Y, Caberoy NB, Alvarado G, Davis J.L., Feuer WJ, Li W. (2011). Identification of Hnrph3 as an autoantigen for acute anterior uveitis. Clin Immunol 138, 60-66.
21. Klein I, Sarkadi B, Varadi A. (1999). An inventory of the human ABC proteins. Biochim Biophys Acta 1461, 237-262.
22. Lee CY, Landreth G.E. (2010). The role of microglia in amyloid clearance from the AD brain. J Neural Transm 117, 949-960.
23. Lee MN, Roy M, Ong S.E., Mertins P., Villani AC, Li W, Dotiwala F, Sen J., Doench JG, Orzalli MH, et al. (2013). Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach. Nature Immunol 14, 179-185.
24. Li W (2012a). Eat-me signals: keys to molecular phagocyte biology and "appetite" control. J Cell Physiol 227, 1291-1297.
25. Li W (2012b). ORF phage display to identify cellular proteins with different functions. Methods 58, 2-9.
26. Li W (2013). Phagocyte dysfunction, tissue aging and degeneration. Ageing Res Rev 12, 1005-1012.
27. Li W, Caberoy N.B. (2010). New perspective for phage display as an ejficient and versatile technology of functional proteomics. Appl Microbiol Biotechnol 85, 909-919.
28. Li W, Handschumacher R.E. (2002). Identification of two calcineurin B-binding proteins: tubulin and heat shock protein 60. Biochim Biophys Acta 1599, 72-81.
29. Neumann H, Takahashi K. (2007). Essential role of the microglial triggering receptor expressed on myeloid cells-2 (TREM2) for central nervous tissue immune homeostasis. J Neuroimmunol 184, 92-99.
30. Ota M, Katsuyama Y, Hamano H., Umemura T, Kimura A, Yoshizawa K., Kiyosawa K, Fukushima H, Bahram S., Inoko H, et al. (2007). Two critical genes (HLA-DRB1 and ABCF1) in the HLA region are associated with the susceptibility to autoimmune pancreatitis. Immunogenetics 59, 45-52.
31. Richard M, Drouin R, Beaulieu A.D. (1998). ABC50, a novel human ATP-binding cassette protein found in tumor necrosis factor-α-stimulated synoviocytes. Genomics 53, 137-145.
32. -/- mouse retina. Proc Natl Acad Sci USA 109, 8145-8148.
33. Salero E, Blenkinsop TA, Corneo B, Harris A., Rabin D, Stern JH, Temple S. (2012). Adult human RPE can be activated into a multipotent stem cell that produces mesenchymal derivatives. Cell Stem Cell 10, 88-95.
34. Sierra A, Abiega O, Shahraz A., Neumann H. (2013). Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis. Front Cell Neurosci 7, 6.
35. Strauss O (2005). The retinal pigment epithelium in visual function. Physiol Rev 85, 845-881.
36. Sun M, Finnemann SC, Febbraio M, Shan L., Annangudi S P, Podrez EA, Hoppe G, Darrow R., Organisciak DT, Salomon RG, et al. (2006). Light-induced oxidation of photoreceptor outer segment phospholipids generates ligands for CD36-mediated phagocytosis by retinal pigment epithelium: a potential mechanism for modulating outer segment phagocytosis under oxidant stress conditions. J Biol Chem 281, 4222-4230.
37. Tyzack JK, Wang X, Belsham G.J., Proud C.G. (2000). ABC50 interacts with eukaryotic initiation factor 2 and associates with the ribosome in an ATP-dependent manner. J Biol Chem 275, 34131-34139.