Inhibition of nitro-oxidative stress attenuates pulmonary and systemic injury induced by high-tidal volume mechanical ventilation

Shock

Volumn 44, Issue 1, 2015, Pages 36-43

  Martínez Caro, Leticia ^a,b,c   Nin, Nicolás ^a   Sánchez Rodríguez, Carolina ^a,c   Ferruelo, Antonio ^a,b   El Assar, Mariam ^a   De Paula, Marta ^a,b   Fernández Segoviano, Pilar ^a,b   Esteban, Andrés ^a,b   Lorente, José A ^a,b,c  

^a HOSPITAL UNIVERSITARIO DE GETAFE   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c UNIVERSIDAD EUROPEA DE MADRID   (Spain)

Author keywords

Acute lung injury; antioxidant; mechanical ventilation; nitric oxide; peroxynitrite; ventilator induced lung injury

Indexed keywords

3 AMINOBENZAMIDE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; MANGANESE TETRAKIS(1 METHYL 4 PYRIDYL)PORPHYRIN; NEURONAL NITRIC OXIDE SYNTHASE; PEROXYNITRITE; UNCLASSIFIED DRUG; 3-AMINOBENZAMIDE; BENZAMIDE DERIVATIVE; ISOENZYME; METALLOPORPHYRIN; MN(III) 5,10,15,20-TETRAKIS(N-METHYLPYRIDINIUM-2-YL)PORPHYRIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

AIRWAY PRESSURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; BLOOD CHEMISTRY; BREATHING MECHANICS; CARDIOVASCULAR FUNCTION; CONTROLLED STUDY; DOWN REGULATION; FLUORESCENCE; GAS EXCHANGE; GENE EXPRESSION; LUNG PARENCHYMA; MALE; MEAN ARTERIAL PRESSURE; MICROSCOPY; NITRATION; NONHUMAN; OXIDATIVE STRESS; OXYGENATION; POSITIVE END EXPIRATORY PRESSURE; PROTEIN EXPRESSION; RAT; TIDAL VOLUME; UPREGULATION; VENTILATOR INDUCED LUNG INJURY; ADVERSE EFFECTS; ANIMAL; DRUG EFFECTS; METABOLISM; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT; VENTILATOR-INDUCED LUNG INJURY;

ANIMALS; BENZAMIDES; ISOENZYMES; MALE; METALLOPORPHYRINS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXIDATIVE STRESS; POLY(ADP-RIBOSE) POLYMERASES; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATION, ARTIFICIAL; VENTILATOR-INDUCED LUNG INJURY;

EID: 84930886402     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0000000000000381     Document Type: Article

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