Administration of a peroxynitrite decomposition catalyst into the bronchial artery attenuates pulmonary dysfunction after smoke inhalation and burn injury in sheep

Shock

Volumn 38, Issue 5, 2012, Pages 543-548

  Hamahata, Atsumori ^a   Enkhbaatar, Perenlei ^b   Lange, Matthias ^b,c   Yamaki, Takashi ^a   Nakazawa, Hiroaki ^d   Nozaki, Motohiro ^a   Sakurai, Hiroyuki ^a   Traber, Lillian D ^b   Traber, Daniel L ^b  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^b University of Texas Medical Branch School of Medicine   (United States)

^c UNIVERSITY OF MÜNSTER   (Germany)

^d NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

bronchial artery; Burn; peroxynitrite; peroxynitrite decomposition catalyst; smoke inhalation; WW 85

Indexed keywords

PEROXYNITRITE; REACTIVE NITROGEN SPECIES; SODIUM CHLORIDE; UNCLASSIFIED DRUG; WW 85;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; BLOOD VESSEL PERMEABILITY; BODY SURFACE; BRONCHIAL ARTERY; BURN; CARDIOPULMONARY HEMODYNAMICS; CATALYST; CONTINUOUS INFUSION; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FLUID RESUSCITATION; HEART RATE; LOW DRUG DOSE; LUNG ARTERY PRESSURE; LUNG BURN; LUNG CIRCULATION; LUNG FLUID; LUNG FUNCTION; LUNG LYMPH FLOW; NITROSATIVE STRESS; NONHUMAN; SHAM PROCEDURE; SHEEP; SMOKE; TISSUE OXYGENATION;

ACUTE LUNG INJURY; ANIMALS; BRONCHIAL ARTERIES; CAPILLARY PERMEABILITY; FEMALE; LUNG; PEROXYNITROUS ACID; SHEEP; SMOKE INHALATION INJURY; TIME FACTORS;

EID: 84868205338     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0b013e31826e9c54     Document Type: Article

References (37)

1. Barrow RE, Spies M, Barrow LN, Herndon DN: Influence of demographics and inhalation injury on burn mortality in children. Burns 30(1):72-77, 2004.
2. Traber DL, Maybauer MO, Maybauer DM, Westphal M, Traber LD: Inhalational and acute lung injury. Shock 24(Suppl 1):82-87, 2005.
3. Enkhbaatar P, Traber DL: Pathophysiology of acute lung injury in combined burn and smoke inhalation injury. Clin Sci (Lond) 107(2):137-143, 2004.
4. Traber DL: Nitric oxide synthase and tissue injury. Shock 14(2):243-244, 2000.
5. Szabo C, Modis K: Pathophysiological roles of peroxynitrite in circulatory shock. Shock 34(Suppl 1):4-14, 2010.
6. Jagtap P, Szabo C: Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors. Nat Rev Drug Discov 4(5):421-440, 2005.
7. Virag L, Szabo C: The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol Rev 54(3):375-429, 2002.
8. Sakurai H, Soejima K, Nozaki M, Traber LD, Traber DL: Effect of ablated airway blood flow on systemic and pulmonary microvascular permeability after smoke inhalation in sheep. Burns 33(7):885-891, 2007.
9. Hamahata A, Enkhbaatar P, Lange M, Cox RA, Hawkins HK, Sakurai H, Traber LD, Traber DL: Direct delivery of low-dose 7-nitroindazole into the bronchial artery attenuates pulmonary pathophysiology after smoke inhalation and burn injury in an ovine model. Shock 36(6):575-579, 2011.
10. Hamahata A, Enkhbaatar P, Sakurai H, Nozaki M, Traber DL: Sclerosis therapy of bronchial artery attenuates acute lung injury induced by burn and smoke inhalation injury in ovine model. Burns 36(7):1642-1649, 2010.
11. Efimova O, Volokhov A, Hales CA: Injection of prostaglandin F2alpha into the bronchial artery in sheep increases the pulmonary vascular permeability to protein. Pulm Pharmacol Ther 20(2):167-171, 2007.
12. Sakurai H, Johnigan R, Kikuchi Y, Harada M, Traber LD, Traber DL: Effect of reduced bronchial circulation on lung fluid flux after smoke inhalation in sheep. J Appl Physiol 84(3):980-986, 1998.
13. Hamahata A, Enkhbaatar P, Hiroyuki S, Morita N, Nakano Y, Lange M, Nozaki M, Traber LD, Traber DL: A novel bronchial artery catheterization technique with preserved blood flow in an ovine model. Exp Lung Res 36(3): 183-189, 2010.
14. Staub NC, Bland RD, Brigham KL, Demling R, Erdmann AJ 3rd, Woolverton WC: Preparation of chronic lung lymph fistulas in sheep. J Surg Res 19(5):315-320, 1975.
15. Traber D, Adams T, Henriksen NJ, Traber D, Thomson P: Reproducibility of cardiopulmonary effects of different endotoxins in the same sheep. J Appl Physiol 54:1167-1171, 1983.
16. Kimura R, Traber LD, Herndon DN, Linares HA, Lubbesmeyer HJ, Traber DL: Increasing duration of smoke exposure induces more severe lung injury in sheep. J Appl Physiol 64(3):1107-1113, 1988.
17. Lange M, Szabo C, Enkhbaatar P, Connelly R, Horvath E, Hamahata A, Cox RA, Esechie A, Nakano Y, Traber LD, et al.: Beneficial pulmonary effects of a metalloporphyrinic peroxynitrite decomposition catalyst in burn and smoke inhalation injury. Am J Physiol Lung Cell Mol Physiol 300(2): L167-L175, 2011.
18. Vidal Melo MF, Harris RS, Layfield D, Musch G, Venegas JG: Changes in regional ventilation after autologous blood clot pulmonary embolism. Anesthesiology 97(3):671-681, 2002.
19. Baxter CR: Problems and complications of burn shock resuscitation. Surg Clin North Am 58(6):1313-1322, 1978.
20. Pearce ML, Yamashita J, Beazell J: Measurement of pulmonary edema. Circ Res 16:482-488, 1965.
21. Soejima K, McGuire R, Snyder NT, Uchida T, Szabo C, Salzman A, Traber LD, Traber DL: The effect of inducible nitric oxide synthase (iNOS) inhibition on smoke inhalation injury in sheep. Shock 13(4):261-266, 2000.
22. Lange M, Enkhbaatar P, Traber DL, Cox RA, Jacob S, Mathew BP, Hamahata A, Traber LD, Herndon DN, Hawkins HK: Role of calcitonin gene-related peptide (CGRP) in ovine burn and smoke inhalation injury. J Appl Physiol 107(1):176-184, 2009.
23. Hassa PO, Hottiger MO: The functional role of poly(ADP-ribose)polymerase 1 as novel coactivator of NF-kappaB in inflammatory disorders. Cell Mol Life Sci 59(9):1534-1553, 2002.
24. Bartha E, Asmussen S, Olah G, Rehberg SW, Yamamoto Y, Traber DL, Szabo C: Burn and smoke injury activates poly(ADP-ribose)polymerase in circulating leukocytes. Shock 36(2):144-148, 2011.
25. Cox RA, Jacob S, Oliveras G, Murakami K, Enkhbaatar P, Traber L, Schmalstieg FC, Herndon DN, Traber DL, Hawkins HK: Pulmonary expression of nitric oxide synthase isoforms in sheep with smoke inhalation and burn injury. Exp Lung Res 35(2):104-118, 2009.
26. Pieper GM, Nilakantan V, Chen M, Zhou J, Khanna AK, Henderson JD Jr, Johnson CP, Roza AM, Szabo C: Protective mechanisms of a metalloporphyrinic peroxynitrite decomposition catalyst, WW85, in rat cardiac transplants. J Pharmacol Exp Ther 314(1):53-60, 2005.
27. Maybauer DM, Maybauer MO, Szabo C, Cox RA, Westphal M, Kiss L, Horvath EM, Traber LD, Hawkins HK, Salzman AL, et al.: The peroxynitrite catalyst WW-85 improves pulmonary function in ovine septic shock. Shock 35(2):148-155, 2011.
28. Genovese T, Mazzon E, Esposito E, Di Paola R, Murthy K, Neville L, Bramanti P, Cuzzocrea S: Effects of a metalloporphyrinic peroxynitrite decomposition catalyst, ww-85, in a mouse model of spinal cord injury. Free Radic Res 43(7):631-645, 2009.
29. Isago T, Noshima S, Traber LD, Herndon DN, Traber DL: Analysis of pulmonary microvascular permeability after smoke inhalation. J Appl Physiol 71(4):1403-1408, 1991.
30. Hales CA, Barkin P, Jung W, Quinn D, Lamborghini D, Burke J: Bronchial artery ligation modifies pulmonary edema after exposure to smoke with acrolein. J Appl Physiol 67(3):1001-1006, 1989.
31. Stothert JC Jr, Ashley KD, Kramer GC, Hebert PC, Traber DL: Intrapulmonary distribution of bronchial blood flow after moderate smoke inhalation. J Appl Physiol 69(5):1734-1739, 1990.
32. Abdi S, Herndon D, McGuire J, Traber L, Traber DL: Time course of alterations in lung lymph and bronchial blood flows after inhalation injury. J Burn Care Rehabil 11(6):510-515, 1990.
33. Hamahata A, Enkhbaatar P, Sakurai H, Nozaki M, Traber DL: Sclerosis therapy of bronchial artery attenuates acute lung injury induced by burn and smoke inhalation injury in ovine model. Burns 36(7):1042-1049, 2010.
34. Hayashi J, Kawarada Y, Isaji S, Yokoi H, Higashiguchi T: Therapeutic effects of continuous intraarterial antibiotic infusion in preventing pancreatic infection in experimental acute necrotizing pancreatitis. Pancreas 13(2):184-192, 1996.
35. Cagol PP, Pasqual E, Bacchetti S: Potential advantages of loco-regional intraarterial chemotherapy. In Vivo 20(6A):777-779, 2006.
36. Traber D, Herndon D, Enkhbaatar P, Maybauer MO, Maybauer DM: The pathophysiology of inhalation injury. In Herndon D, ed. Total Burn Care. Philadelphia, PA: Saunder Elsevier, 248-261, 2007.
37. Fleming RE, Ponka P: Iron overload in human disease. N Engl J Med 366(4): 348-359, 2012.