High tidal volume ventilation induces NOS2 and impairs cAMP-dependent air space fluid clearance

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 284, Issue 5 28-5, 2003, Pages

  Frank, James A ^a,b   Pittet, Jean François ^b   Lee, Hyon ^b   Godzich, Micaela ^b   Matthay, Michael A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acute lung injury; Acute respiratory distress syndrome; Alveolar epithelium; Pulmonary edema; Ventilator induced lung injury

Indexed keywords

CELL PROTEIN; CYCLIC AMP; NITRIC OXIDE SYNTHASE; NITRITE; REACTIVE NITROGEN SPECIES; SURFACTANT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; LUNG ALVEOLUS EPITHELIUM; LUNG CLEARANCE; LUNG EDEMA; LUNG ENDOTHELIUM; LUNG FLUID; LUNG VENTILATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TIDAL VOLUME; VENTILATOR;

EID: 0344406097     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00331.2002     Document Type: Article

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