Disruption of 5-HT1A function in adolescence but not early adulthood leads to sustained increases of anxiety

Neuroscience

Volumn 321, Issue , 2016, Pages 210-221

  Garcia Garcia, A L ^a   Meng, Q ^a   Richardson Jones, J ^a   Dranovsky, A ^a   Leonardo, E D ^a  

^a NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

Author keywords

5 HT1A; Adolescence; Anxiety; Depression; Development; Serotonin

Indexed keywords

N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SEROTONIN; SEROTONIN 1A RECEPTOR; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; CORTICOSTERONE; N-(2-(4-(2-METHOXYPHENYL)-1-PIPERAZINYL)ETHYL)-N-(2-PYRIDINYL)CYCLOHEXANECARBOXAMIDE; PIPERAZINE DERIVATIVE; PYRIDINE DERIVATIVE; SEROTONIN 1 AGONIST; SEROTONIN 1 ANTAGONIST;

AGE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; ELEVATED PLUS MAZE TEST; FORCED SWIM TEST; MALE; MOUSE; NONHUMAN; OPEN FIELD TEST; PERINATAL PERIOD; PHENOTYPE; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAPHE NUCLEUS; SEROTONIN BRAIN LEVEL; SEROTONINERGIC SYSTEM; SUCROSE PREFERENCE TEST; TRANSGENICS; ANIMAL; BLOOD; CONFLICT; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; PSYCHOLOGY; SIGNAL TRANSDUCTION;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; AGE FACTORS; ANIMALS; ANXIETY; CONFLICT (PSYCHOLOGY); CORTICOSTERONE; MALE; MICE, KNOCKOUT; PIPERAZINES; PYRIDINES; RECEPTOR, SEROTONIN, 5-HT1A; SEROTONIN; SEROTONIN 5-HT1 RECEPTOR AGONISTS; SEROTONIN 5-HT1 RECEPTOR ANTAGONISTS; SIGNAL TRANSDUCTION;

EID: 84930847687     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2015.05.076     Document Type: Article

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