메뉴 건너뛰기




Volumn 10, Issue 6, 2014, Pages 841-855

Pro-Chondrogenic Effect of miR-221 and Slug Depletion in Human MSCs

Author keywords

Chondrogenic potential; Gene silencing; Human mesenchymal stem cells; miR 221; Slug

Indexed keywords

MICRORNA; MIRN221 MICRORNA, HUMAN; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR;

EID: 84930824325     PISSN: 26293269     EISSN: 26293277     Source Type: Journal    
DOI: 10.1007/s12015-014-9532-1     Document Type: Review
Times cited : (31)

References (51)
  • 1
    • 34848863384 scopus 로고    scopus 로고
    • Adult mesenchymal stem cells for tissue engineering versus regenerative medicine
    • COI: 1:CAS:528:DC%2BD2sXhtFKnu7rP, PID: 17620285
    • Caplan, A. I. (2007). Adult mesenchymal stem cells for tissue engineering versus regenerative medicine. Journal of Cellular Physiology, 213, 341–347.
    • (2007) Journal of Cellular Physiology , vol.213 , pp. 341-347
    • Caplan, A.I.1
  • 2
    • 58149265734 scopus 로고    scopus 로고
    • The therapeutic applications of multipotential mesenchymal/stromal stem cells in skeletal tissue repair
    • COI: 1:CAS:528:DC%2BD1MXns1SnsQ%3D%3D, PID: 18792913
    • Arthur, A., Zannettino, A., & Gronthos, S. (2009). The therapeutic applications of multipotential mesenchymal/stromal stem cells in skeletal tissue repair. Journal of Cellular Physiology, 218, 237–245.
    • (2009) Journal of Cellular Physiology , vol.218 , pp. 237-245
    • Arthur, A.1    Zannettino, A.2    Gronthos, S.3
  • 3
    • 65249167104 scopus 로고    scopus 로고
    • Cartilage engineering: a crucial combination of cells, biomaterials and biofactors
    • COI: 1:CAS:528:DC%2BD1MXltVyns7o%3D, PID: 19329205
    • Vinatier, C., Mrugala, D., Jorgensen, C., Guicheux, J., & Noël, D. (2009). Cartilage engineering: a crucial combination of cells, biomaterials and biofactors. Trends in Biotechnology, 27, 307–314.
    • (2009) Trends in Biotechnology , vol.27 , pp. 307-314
    • Vinatier, C.1    Mrugala, D.2    Jorgensen, C.3    Guicheux, J.4    Noël, D.5
  • 4
    • 70350243075 scopus 로고    scopus 로고
    • Introducing transcription factors to multipotent mesenchymal stem cells: making transdifferentiation possible
    • COI: 1:CAS:528:DC%2BD1MXhsFenur%2FK, PID: 19591229
    • Barzilay, R., Melamed, E., & Offen, D. (2009). Introducing transcription factors to multipotent mesenchymal stem cells: making transdifferentiation possible. Stem Cells, 27, 2509–2515.
    • (2009) Stem Cells , vol.27 , pp. 2509-2515
    • Barzilay, R.1    Melamed, E.2    Offen, D.3
  • 5
    • 22644444720 scopus 로고    scopus 로고
    • Gene-induced chondrogenesis of primary mesenchymal stem cells in vitro
    • COI: 1:CAS:528:DC%2BD2MXmvVWmtrc%3D, PID: 16043093
    • Palmer, G. D., Steinert, A., Pascher, A., Gouze, E., Gouze, J. N., Betz, O., et al. (2005). Gene-induced chondrogenesis of primary mesenchymal stem cells in vitro. Molecular Therapy, 12, 219–228.
    • (2005) Molecular Therapy , vol.12 , pp. 219-228
    • Palmer, G.D.1    Steinert, A.2    Pascher, A.3    Gouze, E.4    Gouze, J.N.5    Betz, O.6
  • 6
    • 84869090545 scopus 로고    scopus 로고
    • Cell sources for the regeneration of articular cartilage: the past, the horizon and the future
    • COI: 1:CAS:528:DC%2BC38Xhs1ektb%2FO, PID: 23075006
    • Oldershaw, R. A. (2012). Cell sources for the regeneration of articular cartilage: the past, the horizon and the future. International Journal of Experimental Pathology, 93, 389–400.
    • (2012) International Journal of Experimental Pathology , vol.93 , pp. 389-400
    • Oldershaw, R.A.1
  • 7
    • 0035574614 scopus 로고    scopus 로고
    • Regulatory mechanisms in the pathways of cartilage and bone formation
    • PID: 11698188
    • de Crombrugghe, B., Lefebvre, V., & Nakashima, K. (2001). Regulatory mechanisms in the pathways of cartilage and bone formation. Current Opinion in Cell Biology, 13, 721–727.
    • (2001) Current Opinion in Cell Biology , vol.13 , pp. 721-727
    • de Crombrugghe, B.1    Lefebvre, V.2    Nakashima, K.3
  • 9
    • 79953795974 scopus 로고    scopus 로고
    • Concise review: culture mediated changes in fate and/or potency of stem cells
    • COI: 1:CAS:528:DC%2BC3MXmslelsrs%3D, PID: 21305670
    • Roobrouck, V. D., Vanuytsel, K., & Verfaillie, C. M. (2011). Concise review: culture mediated changes in fate and/or potency of stem cells. Stem Cells, 29, 583–589.
    • (2011) Stem Cells , vol.29 , pp. 583-589
    • Roobrouck, V.D.1    Vanuytsel, K.2    Verfaillie, C.M.3
  • 10
    • 4444378185 scopus 로고    scopus 로고
    • Gene Therapy Progress and Prospects. Downregulating gene expression: the impact of RNA interference
    • COI: 1:CAS:528:DC%2BD2cXmt1Wqurs%3D, PID: 15292914
    • Caplen, N. J. (2004). Gene Therapy Progress and Prospects. Downregulating gene expression: the impact of RNA interference. Gene Therapy, 11, 1241–1248.
    • (2004) Gene Therapy , vol.11 , pp. 1241-1248
    • Caplen, N.J.1
  • 11
    • 34249306597 scopus 로고    scopus 로고
    • Regulation and guidance of cell behavior for tissue regeneration via the siRNA mechanism
    • PID: 17537114
    • Cheema, S. K., Chen, E., Shea, L. D., & Mathur, A. B. (2007). Regulation and guidance of cell behavior for tissue regeneration via the siRNA mechanism. Wound Repair and Regeneration, 15, 286–295.
    • (2007) Wound Repair and Regeneration , vol.15 , pp. 286-295
    • Cheema, S.K.1    Chen, E.2    Shea, L.D.3    Mathur, A.B.4
  • 12
    • 35748976970 scopus 로고    scopus 로고
    • Function of the zinc-finger transcription factor SNAI2 in cancer and development
    • COI: 1:CAS:528:DC%2BD1cXnsF2quw%3D%3D
    • Cobaleda, C., Pérez-Caro, M., Vicente-Dueñas, C., & Sánchez-García, I. (2007). Function of the zinc-finger transcription factor SNAI2 in cancer and development. Annual Reviewes Genetics, 41, 41–61.
    • (2007) Annual Reviewes Genetics , vol.41 , pp. 41-61
    • Cobaleda, C.1    Pérez-Caro, M.2    Vicente-Dueñas, C.3    Sánchez-García, I.4
  • 13
    • 83455236760 scopus 로고    scopus 로고
    • miR221/222 in cancer: their role in tumor progression and response to therapy
    • COI: 1:CAS:528:DC%2BC38XitVeitbY%3D, PID: 22082479
    • Garofalo, M., Quintavalle, C., Romano, G., Croce, C. M., & Condorelli, G. (2012). miR221/222 in cancer: their role in tumor progression and response to therapy. Current Molecular Medicine, 12, 27–33.
    • (2012) Current Molecular Medicine , vol.12 , pp. 27-33
    • Garofalo, M.1    Quintavalle, C.2    Romano, G.3    Croce, C.M.4    Condorelli, G.5
  • 14
    • 0142211292 scopus 로고    scopus 로고
    • Mouse Snail family transcription repressors regulate chondrocyte, extracellular matrix, type II collagen, and aggrecan
    • COI: 1:CAS:528:DC%2BD3sXot1amsbs%3D, PID: 12917416
    • Seki, K., Fujimori, T., Savagner, P., Hata, A., Aikawa, T., Ogata, N., et al. (2003). Mouse Snail family transcription repressors regulate chondrocyte, extracellular matrix, type II collagen, and aggrecan. Journal of Biological Chemistry, 278, 41862–41870.
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 41862-41870
    • Seki, K.1    Fujimori, T.2    Savagner, P.3    Hata, A.4    Aikawa, T.5    Ogata, N.6
  • 16
    • 77956239114 scopus 로고    scopus 로고
    • MicroRNA-221 regulates chondrogenic differentiation through promoting proteosomal degradation of slug by targeting Mdm2
    • COI: 1:CAS:528:DC%2BC3cXhtVKhs7zJ, PID: 20576614
    • Kim, D., Song, J., & Jin, E. J. (2010). MicroRNA-221 regulates chondrogenic differentiation through promoting proteosomal degradation of slug by targeting Mdm2. Journal of Biological Chemistry, 285, 26900–26907.
    • (2010) Journal of Biological Chemistry , vol.285 , pp. 26900-26907
    • Kim, D.1    Song, J.2    Jin, E.J.3
  • 17
    • 84866079794 scopus 로고    scopus 로고
    • A microRNA signature associated with chondrogenic lineage commitment
    • COI: 1:CAS:528:DC%2BC38XhtlWlurzM, PID: 22942087
    • Bakhshandeh, B., Soleimani, M., Paylakhi, S. H., & Ghaemi, N. (2012). A microRNA signature associated with chondrogenic lineage commitment. Journal of Genetics, 91, 171–182.
    • (2012) Journal of Genetics , vol.91 , pp. 171-182
    • Bakhshandeh, B.1    Soleimani, M.2    Paylakhi, S.H.3    Ghaemi, N.4
  • 18
    • 79551505437 scopus 로고    scopus 로고
    • Human primary articular chondrocytes, chondroblasts-like cells, and dedifferentiated chondrocytes: differences in gene, microRNA, and protein expression and phenotype
    • COI: 1:CAS:528:DC%2BC3MXht1yrt7w%3D, PID: 20799885
    • Karlsen, T. A., Shahdadfar, A., & Brinchmann, J. E. (2011). Human primary articular chondrocytes, chondroblasts-like cells, and dedifferentiated chondrocytes: differences in gene, microRNA, and protein expression and phenotype. Tissue Engineering. Part C, Methods, 17, 219–227.
    • (2011) Tissue Engineering. Part C, Methods , vol.17 , pp. 219-227
    • Karlsen, T.A.1    Shahdadfar, A.2    Brinchmann, J.E.3
  • 19
    • 0033916759 scopus 로고    scopus 로고
    • Human slug is a repressor that localizes to sites of active transcription
    • COI: 1:CAS:528:DC%2BD3cXks1OjsrY%3D, PID: 10866665
    • Hemavathy, K., Guru, S. C., Harris, J., Chen, J. D., & Ip, Y. T. (2000). Human slug is a repressor that localizes to sites of active transcription. Molecular and Cellular Biology, 20, 5087–5095.
    • (2000) Molecular and Cellular Biology , vol.20 , pp. 5087-5095
    • Hemavathy, K.1    Guru, S.C.2    Harris, J.3    Chen, J.D.4    Ip, Y.T.5
  • 20
    • 70350660698 scopus 로고    scopus 로고
    • Concerted stimuli regulating osteo-chondral differentiation from stem cells: phenotype acquisition regulated by microRNAs
    • COI: 1:CAS:528:DC%2BD1MXht1Whs73O, PID: 19801995
    • Gordeladze, J. O., Djouad, F., Brondello, J. M., Noël, D., Duroux-Richard, I., Apparailly, F., et al. (2009). Concerted stimuli regulating osteo-chondral differentiation from stem cells: phenotype acquisition regulated by microRNAs. Acta Pharmacologica Sinica, 30, 1369–1384.
    • (2009) Acta Pharmacologica Sinica , vol.30 , pp. 1369-1384
    • Gordeladze, J.O.1    Djouad, F.2    Brondello, J.M.3    Noël, D.4    Duroux-Richard, I.5    Apparailly, F.6
  • 21
    • 79960569238 scopus 로고    scopus 로고
    • MicroRNA-145 regulates chondrogenic differentiation of mesenchymal stem cells by targeting Sox9
    • COI: 1:CAS:528:DC%2BC3MXhtVCgurbP, PID: 21799743
    • Yang, B., Guo, H., Zhang, Y., Chen, L., Ying, D., & Dong, S. (2011). MicroRNA-145 regulates chondrogenic differentiation of mesenchymal stem cells by targeting Sox9. PloS One, 6, e21679.
    • (2011) PloS One , vol.6 , pp. e21679
    • Yang, B.1    Guo, H.2    Zhang, Y.3    Chen, L.4    Ying, D.5    Dong, S.6
  • 22
    • 84869063717 scopus 로고    scopus 로고
    • MicroRNAs in chondrogenesis, articular cartilage, and osteoarthritis: implications for tissue engineering
    • COI: 1:CAS:528:DC%2BC38Xhs1GltrjM
    • Hong, E., & Reddi, A. H. (2012). MicroRNAs in chondrogenesis, articular cartilage, and osteoarthritis: implications for tissue engineering. Tissue Engineering Part B, 18, 445–453.
    • (2012) Tissue Engineering Part B , vol.18 , pp. 445-453
    • Hong, E.1    Reddi, A.H.2
  • 24
    • 33645571747 scopus 로고    scopus 로고
    • Immunolocalization of matrix proteins in different human cartilage subtypes
    • COI: 1:CAS:528:DC%2BD28Xls1Srs7w%3D, PID: 16493578
    • Wachsmuth, L., Soder, S., Fan, Z., Finger, F., & Aigner, T. (2006). Immunolocalization of matrix proteins in different human cartilage subtypes. Histology and Histopathology, 21, 477–485.
    • (2006) Histology and Histopathology , vol.21 , pp. 477-485
    • Wachsmuth, L.1    Soder, S.2    Fan, Z.3    Finger, F.4    Aigner, T.5
  • 25
    • 38149042741 scopus 로고    scopus 로고
    • Engineered cartilage generated by nasal chondrocytes is responsive to physical forces resembling joint loading
    • COI: 1:CAS:528:DC%2BD1cXhslOjt7k%3D, PID: 18163475
    • Candrian, C., Vonwil, D., Barbero, A., Bonacina, E., Miot, S., Farhadi, J., et al. (2008). Engineered cartilage generated by nasal chondrocytes is responsive to physical forces resembling joint loading. Arthritis and Rheumatism, 58, 197–208.
    • (2008) Arthritis and Rheumatism , vol.58 , pp. 197-208
    • Candrian, C.1    Vonwil, D.2    Barbero, A.3    Bonacina, E.4    Miot, S.5    Farhadi, J.6
  • 26
    • 84898426424 scopus 로고    scopus 로고
    • The in vitro and in vivo capacity of culture-expanded human cells from several sources encapsulated in alginate to form cartilage
    • COI: 1:CAS:528:DC%2BC2cXhsVWis7jM, PID: 24706178
    • Pleumeekers, M. M., Nimeskern, L., Koevoet, W. L., Kops, N., Poublon, R. M., Stok, K. S., et al. (2014). The in vitro and in vivo capacity of culture-expanded human cells from several sources encapsulated in alginate to form cartilage. European Cells and Materials, 27, 264–280.
    • (2014) European Cells and Materials , vol.27 , pp. 264-280
    • Pleumeekers, M.M.1    Nimeskern, L.2    Koevoet, W.L.3    Kops, N.4    Poublon, R.M.5    Stok, K.S.6
  • 29
    • 84866788059 scopus 로고    scopus 로고
    • Correlation between slug transcription factor and miR-221 in MDA-MB-231 breast cancer cells
    • COI: 1:CAS:528:DC%2BC3sXjtVKit7s%3D, PID: 23031797
    • Lambertini, E., Lolli, A., Vezzali, F., Penolazzi, L., Gambari, R., & Piva, R. (2012). Correlation between slug transcription factor and miR-221 in MDA-MB-231 breast cancer cells. BMC Cancer, 12, 445.
    • (2012) BMC Cancer , vol.12 , pp. 445
    • Lambertini, E.1    Lolli, A.2    Vezzali, F.3    Penolazzi, L.4    Gambari, R.5    Piva, R.6
  • 30
    • 58149316623 scopus 로고    scopus 로고
    • Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3
    • COI: 1:CAS:528:DC%2BD1cXhtlKqtr7I, PID: 18799618
    • Medici, D., Hay, E. D., & Olsen, B. R. (2008). Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3. Molecular Biology of the Cell, 19, 4875–4887.
    • (2008) Molecular Biology of the Cell , vol.19 , pp. 4875-4887
    • Medici, D.1    Hay, E.D.2    Olsen, B.R.3
  • 31
    • 78649755556 scopus 로고    scopus 로고
    • IKK(α) controls canonical TGF(ß)-SMAD signaling to regulate genes expressing SNAIL and SLUG during EMT in panc1 cells
    • COI: 1:CAS:528:DC%2BC3MXhtV2qsro%3D, PID: 21081648
    • Brandl, M., Seidler, B., Haller, F., Adamski, J., Schmid, R. M., Saur, D., et al. (2010). IKK(α) controls canonical TGF(ß)-SMAD signaling to regulate genes expressing SNAIL and SLUG during EMT in panc1 cells. Journal of Cell Science, 123, 4231–4239.
    • (2010) Journal of Cell Science , vol.123 , pp. 4231-4239
    • Brandl, M.1    Seidler, B.2    Haller, F.3    Adamski, J.4    Schmid, R.M.5    Saur, D.6
  • 32
    • 0035794663 scopus 로고    scopus 로고
    • Transcriptional repression and developmental functions of the atypical vertebrate GATA protein TRPS1
    • COI: 1:CAS:528:DC%2BD3MXivVCrsrc%3D, PID: 11285235
    • Malik, T. H., Shoichet, S. A., Latham, P., Kroll, T. G., Peters, L. L., & Shivdasani, R. A. (2001). Transcriptional repression and developmental functions of the atypical vertebrate GATA protein TRPS1. EMBO Journal, 20, 1715–1725.
    • (2001) EMBO Journal , vol.20 , pp. 1715-1725
    • Malik, T.H.1    Shoichet, S.A.2    Latham, P.3    Kroll, T.G.4    Peters, L.L.5    Shivdasani, R.A.6
  • 34
    • 26844502418 scopus 로고    scopus 로고
    • Transcriptional control of chondrocyte fate and differentiation
    • COI: 1:CAS:528:DC%2BD2MXhtFGju7zE
    • Lefebvre, V., & Smits, P. (2005). Transcriptional control of chondrocyte fate and differentiation. Birth Defects Research Part C, 75, 200–212.
    • (2005) Birth Defects Research Part C , vol.75 , pp. 200-212
    • Lefebvre, V.1    Smits, P.2
  • 35
    • 77955593347 scopus 로고    scopus 로고
    • microRNA: a master regulator of cellular processes for bioengineering systems
    • COI: 1:CAS:528:DC%2BC3cXhtFais77L
    • Sun, W., Julie Li, Y. S., Huang, H. D., Shyy, J. Y., & Chien, S. (2010). microRNA: a master regulator of cellular processes for bioengineering systems. Annual Reviews Biomedical Engineering, 12, 1–27.
    • (2010) Annual Reviews Biomedical Engineering , vol.12 , pp. 1-27
    • Sun, W.1    Julie Li, Y.S.2    Huang, H.D.3    Shyy, J.Y.4    Chien, S.5
  • 36
    • 84872199561 scopus 로고    scopus 로고
    • How microRNAs facilitate reprogramming to pluripotency
    • COI: 1:CAS:528:DC%2BC38XhvVGntb%2FP, PID: 23077173
    • Anokye-Danso, F., Snitow, M., & Morrisey, E. E. (2012). How microRNAs facilitate reprogramming to pluripotency. Journal of Cell Science, 125, 4179–4187.
    • (2012) Journal of Cell Science , vol.125 , pp. 4179-4187
    • Anokye-Danso, F.1    Snitow, M.2    Morrisey, E.E.3
  • 38
    • 79960789217 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 primes human mesenchymal stem cells for enhanced chondrogenesis
    • COI: 1:CAS:528:DC%2BC3MXhtVOrsbfL, PID: 21818404
    • Handorf, A. M., & Li, W. J. (2011). Fibroblast growth factor-2 primes human mesenchymal stem cells for enhanced chondrogenesis. PloS One, 6, e22887.
    • (2011) PloS One , vol.6 , pp. e22887
    • Handorf, A.M.1    Li, W.J.2
  • 39
    • 0033983594 scopus 로고    scopus 로고
    • Review: tissue engineering for regeneration of articular cartilage
    • COI: 1:CAS:528:DC%2BD3cXhtVykt78%3D, PID: 10674807
    • Temenoff, J. S., & Mikos, A. G. (2000). Review: tissue engineering for regeneration of articular cartilage. Biomaterials, 21, 431–440.
    • (2000) Biomaterials , vol.21 , pp. 431-440
    • Temenoff, J.S.1    Mikos, A.G.2
  • 40
    • 84865531619 scopus 로고    scopus 로고
    • Time-dependent processes in stem cell-based tissue engineering of articular cartilage
    • COI: 1:CAS:528:DC%2BC38XhtFKlsLvE, PID: 22016073
    • Gadjanski, I., Spiller, K., & Vunjak-Novakovic, G. (2012). Time-dependent processes in stem cell-based tissue engineering of articular cartilage. Stem Cell Reviews and Reports, 8, 863–881.
    • (2012) Stem Cell Reviews and Reports , vol.8 , pp. 863-881
    • Gadjanski, I.1    Spiller, K.2    Vunjak-Novakovic, G.3
  • 42
    • 0033986279 scopus 로고    scopus 로고
    • Osteoarthritis-like changes in the murine knee joint resulting from intra-articular transforming growth factor-b injections
    • PID: 10607496
    • van Beuningen, H. M., Glansbeek, H. L., van der Kraan, P. M., & van den Berg, W. B. (2000). Osteoarthritis-like changes in the murine knee joint resulting from intra-articular transforming growth factor-b injections. Osteoarthritis and Cartilage, 8, 25–33.
    • (2000) Osteoarthritis and Cartilage , vol.8 , pp. 25-33
    • van Beuningen, H.M.1    Glansbeek, H.L.2    van der Kraan, P.M.3    van den Berg, W.B.4
  • 43
    • 84865289572 scopus 로고    scopus 로고
    • TGFβ inhibition during expansion phase increases the chondrogenic re-differentiation capacity of human articular chondrocytes
    • COI: 1:STN:280:DC%2BC38jotFCjtw%3D%3D, PID: 22772045
    • Narcisi, R., Signorile, L., Verhaar, J. A., Giannoni, P., & van Osch, G. J. (2012). TGFβ inhibition during expansion phase increases the chondrogenic re-differentiation capacity of human articular chondrocytes. Osteoarthritis and Cartilage, 20, 1152–1160.
    • (2012) Osteoarthritis and Cartilage , vol.20 , pp. 1152-1160
    • Narcisi, R.1    Signorile, L.2    Verhaar, J.A.3    Giannoni, P.4    van Osch, G.J.5
  • 44
    • 84891544687 scopus 로고    scopus 로고
    • Chondrogenesis of mesenchymal stem cells in an osteochondral environment is mediated by the subchondral bone
    • PID: 23980750
    • de Vries-van Melle, M. L., Narcisi, R., Kops, N., Koevoet, W. J., Bos, P. K., Murphy, J. M., et al. (2014). Chondrogenesis of mesenchymal stem cells in an osteochondral environment is mediated by the subchondral bone. Tissue Engineering. Part A, 20, 23–33.
    • (2014) Tissue Engineering. Part A , vol.20 , pp. 23-33
    • de Vries-van Melle, M.L.1    Narcisi, R.2    Kops, N.3    Koevoet, W.J.4    Bos, P.K.5    Murphy, J.M.6
  • 45
    • 84880297184 scopus 로고    scopus 로고
    • Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis
    • COI: 1:CAS:528:DC%2BC3sXnvVSjur4%3D, PID: 23685840
    • Zhen, G., Wen, C., Jia, X., Li, Y., Crane, J. L., Mears, S. C., et al. (2013). Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis. Nature Medicine, 19, 704–712.
    • (2013) Nature Medicine , vol.19 , pp. 704-712
    • Zhen, G.1    Wen, C.2    Jia, X.3    Li, Y.4    Crane, J.L.5    Mears, S.C.6
  • 46
    • 61349108694 scopus 로고    scopus 로고
    • Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3
    • COI: 1:CAS:528:DC%2BD1MXivVentLg%3D, PID: 19389374
    • Wuelling, M., Kaiser, F. J., Buelens, L. A., Braunholz, D., Shivdasani, R. A., Depping, R., et al. (2009). Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3. Developmental Biology, 328, 40–53.
    • (2009) Developmental Biology , vol.328 , pp. 40-53
    • Wuelling, M.1    Kaiser, F.J.2    Buelens, L.A.3    Braunholz, D.4    Shivdasani, R.A.5    Depping, R.6
  • 47
    • 69849114685 scopus 로고    scopus 로고
    • Three-dimensional cultures of osteogenic and chondrogenic cells: a tissue engineering approach to mimic bone and cartilage in vitro
    • COI: 1:CAS:528:DC%2BD1MXovVSrs78%3D
    • Tortelli, F., & Cancedda, R. (2009). Three-dimensional cultures of osteogenic and chondrogenic cells: a tissue engineering approach to mimic bone and cartilage in vitro. European Cells & Materials, 17, 1–14.
    • (2009) European Cells & Materials , vol.17 , pp. 1-14
    • Tortelli, F.1    Cancedda, R.2
  • 48
    • 84865301793 scopus 로고    scopus 로고
    • Redifferentiation of dedifferentiated human articular chondrocytes: comparison of 2D and 3D cultures
    • COI: 1:STN:280:DC%2BC38fgtVertA%3D%3D, PID: 22796508
    • Caron, M. M., Emans, P. J., Coolsen, M. M., Voss, L., Surtel, D. A., Cremers, A., et al. (2012). Redifferentiation of dedifferentiated human articular chondrocytes: comparison of 2D and 3D cultures. Osteoarthritis and Cartilage, 20, 1170–1178.
    • (2012) Osteoarthritis and Cartilage , vol.20 , pp. 1170-1178
    • Caron, M.M.1    Emans, P.J.2    Coolsen, M.M.3    Voss, L.4    Surtel, D.A.5    Cremers, A.6
  • 49
    • 84911881373 scopus 로고    scopus 로고
    • Lisignoli, G., Manferdini, C., Lambertini, E., Zini, N., Angelozzi, M., Gabusi, E., et al. Chondrogenic Potential of Slug-depleted hMSCs. Tissue Eng Part A, in press
    • Lisignoli, G., Manferdini, C., Lambertini, E., Zini, N., Angelozzi, M., Gabusi, E., et al. Chondrogenic Potential of Slug-depleted hMSCs. Tissue Eng Part A, in press. doi:10.1089/ten.TEA.2013.0343.
  • 50
    • 84857444112 scopus 로고    scopus 로고
    • Chondrogenesis and cartilage tissue engineering: the longer road to technology development
    • Mahmoudifa, N., & Doran, P. M. (2012). Chondrogenesis and cartilage tissue engineering: the longer road to technology development. Trends in Biotechnology, 30, 166–176.
    • (2012) Trends in Biotechnology , vol.30 , pp. 166-176
    • Mahmoudifa, N.1    Doran, P.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.