Potential roles of cytokines and chemokines in human intervertebral disc degeneration: Interleukin-1 is a master regulator of catabolic processes

Osteoarthritis and Cartilage

Volumn 23, Issue 7, 2015, Pages 1165-1177

  Phillips, K L E ^a   Cullen, K ^b   Chiverton, N ^c   Michael, A L R ^c   Cole, A A ^c   Breakwell, L M ^c   Haddock, G ^a   Bunning, R A D ^a   Cross, A K ^a   Le Maitre, C L ^a  

^a SHEFFIELD HALLAM UNIVERSITY   (United Kingdom)

^b ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

^c SHEFFIELD TEACHING HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Chemokine receptors; Cytokine; Interleukin 1; Intervertebral disc degeneration

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; COLONY STIMULATING FACTOR 2; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CHEMOKINE; CHEMOKINE RECEPTOR; CYTOKINE; CYTOKINE RECEPTOR;

ARTICLE; BONE REMODELING; CATABOLISM; CCR1 GENE; CD4 GENE; CELL INFILTRATION; CLINICAL ARTICLE; CONTROLLED STUDY; CXCR1 GENE; CXCR2 GENE; CYTOKINE RELEASE; ENZYME DEGRADATION; EXTRACELLULAR MATRIX; GENE; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; HUMAN TISSUE; IL 1BETA GENE; IL1 GENE; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOGENESIS; INTERVERTEBRAL DISK DEGENERATION; NUCLEUS PULPOSUS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; ADULT; AGED; BIOSYNTHESIS; CELL CULTURE; GENE EXPRESSION REGULATION; IMMUNOLOGY; LUMBAR VERTEBRA; METABOLISM; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; YOUNG ADULT;

ADULT; AGED; CELLS, CULTURED; CHEMOKINES; CYTOKINES; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-1BETA; INTERVERTEBRAL DISC DEGENERATION; LUMBAR VERTEBRAE; MIDDLE AGED; RECEPTORS, CHEMOKINE; RECEPTORS, CYTOKINE; YOUNG ADULT;

EID: 84930822016     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2015.02.017     Document Type: Article

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