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Volumn 53, Issue 7, 2015, Pages 1052-1057

Leishmanicidal and cytotoxic activities of Nigella sativa and its active principle, thymoquinone

Author keywords

Black cumin; Leishmania infantum; Leishmania tropica

Indexed keywords

CARVACROL; ESSENTIAL OIL; LONGIFOLENE; MEGLUMINE ANTIMONATE; METHANOL; NIGELLA SATIVA EXTRACT; PARA CYMENE; PLANT MEDICINAL PRODUCT; TERPINEN 4 OL; THYMOQUINONE; UNCLASSIFIED DRUG; ANTIPROTOZOAL AGENT; BENZOQUINONE DERIVATIVE; CYTOTOXIN; PLANT EXTRACT;

EID: 84930814283     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2014.957784     Document Type: Article
Times cited : (62)

References (33)
  • 2
    • 0018611973 scopus 로고
    • Antimicrobial and anthelmintic activities of the essential oil of Nigella sativa Linn
    • Agrawal R, Kharya MD, Shrivastava R. (1979). Antimicrobial and anthelmintic activities of the essential oil of Nigella sativa Linn. Indian J Exp Biol 17:1264-5.
    • (1979) Indian J Exp Biol , vol.17 , pp. 1264-1265
    • Agrawal, R.1    Kharya, M.D.2    Shrivastava, R.3
  • 3
    • 0038559976 scopus 로고    scopus 로고
    • Pharmacological and toxicological properties of Nigella sativa
    • Ali B, Blunden G. (2009). Pharmacological and toxicological properties of Nigella sativa. Phytother Res 17:299-305.
    • (2009) Phytother Res , vol.17 , pp. 299-305
    • Ali, B.1    Blunden, G.2
  • 4
    • 0031680253 scopus 로고    scopus 로고
    • Acute and subchronic toxicity of thymoquinone in mice
    • Badary OA, Al-Shabanah OA, Nagi MN, et al. (1998). Acute and subchronic toxicity of thymoquinone in mice. Drug Dev Res 44: 56-61.
    • (1998) Drug Dev Res , vol.44 , pp. 56-61
    • Badary, O.A.1    Al-Shabanah, O.A.2    Nagi, M.N.3
  • 5
    • 0033825073 scopus 로고    scopus 로고
    • Leishmania infantum: Stage specific activity of pentavalent antimony related with the assay conditions
    • Carrio MC, Reiva C, Gallego M, et al. (2000). Leishmania infantum: Stage specific activity of pentavalent antimony related with the assay conditions. Exp Parasitol 95:209-14.
    • (2000) Exp Parasitol , vol.95 , pp. 209-214
    • Carrio, M.C.1    Reiva, C.2    Gallego, M.3
  • 7
    • 0032861743 scopus 로고    scopus 로고
    • Plant products as antimicrobial agents
    • Cowan MM. (1999). Plant products as antimicrobial agents. Clin Microb Rev 12:564-82.
    • (1999) Clin Microb Rev , vol.12 , pp. 564-582
    • Cowan, M.M.1
  • 8
    • 3042555141 scopus 로고    scopus 로고
    • Leishmaniasis: Current situation and new perspectives
    • Desjeux P. (2004). Leishmaniasis: Current situation and new perspectives. Comp Immunol, Microbiol Infect Dis 27:305-18.
    • (2004) Comp Immunol, Microbiol Infect Dis , vol.27 , pp. 305-318
    • Desjeux, P.1
  • 9
    • 77951900223 scopus 로고    scopus 로고
    • Chemical composition and antiprotozoal activities of Colombian Lippia spp essential oils and their major components
    • Escobar P, Milena Leal S, Herrera LV, et al. (2010). Chemical composition and antiprotozoal activities of Colombian Lippia spp essential oils and their major components. Mem Inst Oswaldo Cruz 105:184-90.
    • (2010) Mem Inst Oswaldo Cruz , vol.105 , pp. 184-190
    • Escobar, P.1    Milena Leal, S.2    Herrera, L.V.3
  • 10
    • 0031863041 scopus 로고    scopus 로고
    • Protective effect of cysteine and vitamin E, Crocus sativus and Nigella sativa extracts on cisplatin induced toxicity in rats
    • El Daly ES. (1998). Protective effect of cysteine and vitamin E, Crocus sativus and Nigella sativa extracts on cisplatin induced toxicity in rats. J Pharm Belg 53:87-95.
    • (1998) J Pharm Belg , vol.53 , pp. 87-95
    • El Daly, E.S.1
  • 11
    • 3242670931 scopus 로고    scopus 로고
    • Mechanisms of the hypoglycaemic and immunopotentiating effects of Nigella sativa L. Oil in streptozotocin-induced diabetic hamsters
    • Fararh KM, Atoji Y, Shimizu Y, et al. (2004). Mechanisms of the hypoglycaemic and immunopotentiating effects of Nigella sativa L. oil in streptozotocin-induced diabetic hamsters. Res Vet Sci 77:123-9.
    • (2004) Res Vet Sci , vol.77 , pp. 123-129
    • Fararh, K.M.1    Atoji, Y.2    Shimizu, Y.3
  • 12
    • 85036435490 scopus 로고    scopus 로고
    • The in vivo antileishmanial activity of alcoholic extract from Nigella sativa seeds
    • Fattahi Bafghi A, Vahidi AR, Anvari MH, et al. (2011). The in vivo antileishmanial activity of alcoholic extract from Nigella sativa seeds. Afr J Microbiol Res 5:1504-10.
    • (2011) Afr J Microbiol Res , vol.5 , pp. 1504-1510
    • Fattahi Bafghi, A.1    Vahidi, A.R.2    Anvari, M.H.3
  • 13
    • 84880743783 scopus 로고    scopus 로고
    • Prevalence, hematology, and treatment of balantidiasis among donkeys in and around Lahore, Pakistan
    • Khan A, Khan MS, Avais M, et al. (2013). Prevalence, hematology, and treatment of balantidiasis among donkeys in and around Lahore, Pakistan. Vet Parasitol 196:203-5.
    • (2013) Vet Parasitol , vol.196 , pp. 203-205
    • Khan, A.1    Khan, M.S.2    Avais, M.3
  • 14
    • 0037326010 scopus 로고    scopus 로고
    • The in vivo antifungal activity of the aqueous extract from Nigella sativa seed
    • Khan MA, Ashfaq MK, Zuberi HS, Zuberi AH. (2003). The in vivo antifungal activity of the aqueous extract from Nigella sativa seed. Phytother Res 17:183-6.
    • (2003) Phytother Res , vol.17 , pp. 183-186
    • Ma, K.1    Ashfaq, M.K.2    Zuberi, H.S.3    Zuberi, A.H.4
  • 15
    • 0027379097 scopus 로고
    • CNS and analgesic studies on Nigella sativa
    • Khanna T, Zaidi FA, Dandiya PC. (1993). CNS and analgesic studies on Nigella sativa. Fitoterapia 5:407-10.
    • (1993) Fitoterapia , vol.5 , pp. 407-410
    • Khanna, T.1    Zaidi, F.A.2    Dandiya, P.C.3
  • 16
    • 0036136661 scopus 로고    scopus 로고
    • The effects of Nigella sativa oil against the liver damage induced by Schistosoma mansoni in mice
    • Mahmoud MR, El-Abhar HS, Saleh S. (2002). The effects of Nigella sativa oil against the liver damage induced by Schistosoma mansoni in mice. J Ethnopharmacol 79:1-11.
    • (2002) J Ethnopharmacol , vol.79 , pp. 1-11
    • Mahmoud, M.R.1    El-Abhar, H.S.2    Saleh, S.3
  • 17
    • 84914160001 scopus 로고    scopus 로고
    • Antileishmania effects of methotrexate (MTX) alone and in combination with meglumine antimoniate (MA) against Iranian isolate of sensitive and MA-resistant Leishmania tropica: An in-vitro assay
    • Mahmoudvand H, Sharifi I, Fasihi Harandi M, et al. (2014a). Antileishmania effects of methotrexate (MTX) alone and in combination with meglumine antimoniate (MA) against Iranian isolate of sensitive and MA-resistant Leishmania tropica: An in-vitro assay. Asian Pacific J Trop Med 7:412-20.
    • Asian Pacific J Trop Med , vol.7 , pp. 412-420
    • Mahmoudvand, H.1    Sharifi, I.2    Fasihi Harandi, M.3
  • 18
    • 84896037115 scopus 로고    scopus 로고
    • In vitro inhibitory effect of Berberis vulgaris (Berberidaceae) and its main component, berberine against different Leishmania species
    • Mahmoudvand H, Sharififar F, Sharifi I, et al. (2014b). In vitro inhibitory effect of Berberis vulgaris (Berberidaceae) and its main component, berberine against different Leishmania species. Iranian J Parasitol 9:28-36.
    • (2014) Iranian J Parasitol , vol.9 , pp. 28-36
    • Mahmoudvand, H.1    Sharififar, F.2    Sharifi, I.3
  • 19
    • 0026498303 scopus 로고
    • Antibiotic screening of medicinal plants of the British Columbian native peoples
    • McCutcheon AR, Ellis SM, Hancock REW, Tower GNH. (1992). Antibiotic screening of medicinal plants of the British Columbian native peoples. J Ethnopharmacol 37:213-23.
    • (1992) J Ethnopharmacol , vol.37 , pp. 213-223
    • McCutcheon, A.R.1    Ellis, S.M.2    Hancock, R.E.W.3    Tower, G.N.H.4
  • 20
    • 84888817107 scopus 로고    scopus 로고
    • Essential oil from Chenopodium ambrosioides and main components: Activity against Leishmania, their mitochondria and other microorganisms
    • Monzote L, Garcá M, Pastor J, et al. (2014). Essential oil from Chenopodium ambrosioides and main components: Activity against Leishmania, their mitochondria and other microorganisms. Exp Parasitol 136:20-6.
    • (2014) Exp Parasitol , vol.136 , pp. 20-26
    • Monzote, L.1    Garcá, M.2    Pastor, J.3
  • 21
    • 0033945636 scopus 로고    scopus 로고
    • Antimicrobial effect of crude extracts of Nigella sativa on multiple antibiotics-resistant bacteria
    • Morsi NM. (2000). Antimicrobial effect of crude extracts of Nigella sativa on multiple antibiotics-resistant bacteria. Acta Microbiol Poland 49:63-74.
    • (2000) Acta Microbiol Poland , vol.49 , pp. 63-74
    • Morsi, N.M.1
  • 22
    • 84881290775 scopus 로고    scopus 로고
    • Treating Cryptosporidium parvum infection in calves
    • Nasir A, Avais M, Khan MS, et al. (2013). Treating Cryptosporidium parvum infection in calves. J Parasitol 99:715-17.
    • (2013) J Parasitol , vol.99 , pp. 715-717
    • Nasir, A.1    Avais, M.2    Khan, M.S.3
  • 23
    • 84916629979 scopus 로고    scopus 로고
    • Efficacy of adding topical honey-based hydroalcoholic extract Nigella sativa 60% compared to honey alone in patients with cutaneous leishmaniasis receiving intralesional glucantime
    • Nilforoushzadeh MA, Hejazi SH, Zarkoob H, et al. (2010). Efficacy of adding topical honey-based hydroalcoholic extract Nigella sativa 60% compared to honey alone in patients with cutaneous leishmaniasis receiving intralesional glucantime. J Skin Leishmaniasis 1:26-31.
    • (2010) J Skin Leishmaniasis , vol.1 , pp. 26-31
    • Ma, N.1    Hejazi, S.H.2    Zarkoob, H.3
  • 24
    • 79959380543 scopus 로고    scopus 로고
    • Antimalarial and antioxidant activities of methanolic extract of Nigella sativa seeds (black cumin) in mice infected with Plasmodium yoelli nigeriensis
    • Okeola VO, Adaramoye OA, Nneji CM, et al. (2011). Antimalarial and antioxidant activities of methanolic extract of Nigella sativa seeds (black cumin) in mice infected with Plasmodium yoelli nigeriensis. Parasitol Res 108:1507-12.
    • (2011) Parasitol Res , vol.108 , pp. 1507-1512
    • Okeola, V.O.1    Adaramoye, O.A.2    Nneji, C.M.3
  • 25
    • 24644459814 scopus 로고    scopus 로고
    • A review of the pharmacotherapeutic effects of Nigella sativa
    • Randhawa MA, Al-Ghamdi MS. (2002). A review of the pharmacotherapeutic effects of Nigella sativa. Pak J Med Res 41:77-83.
    • (2002) Pak J Med Res , vol.41 , pp. 77-83
    • Ma, R.1    Al-Ghamdi, M.S.2
  • 27
    • 84893248952 scopus 로고    scopus 로고
    • Leishmanicidal activity of a daucane sesquiterpene isolated from Eryngium foetidum
    • Rojas-Silva P, Graziose R, Vesely B, et al. (2014). Leishmanicidal activity of a daucane sesquiterpene isolated from Eryngium foetidum. Pharm Biol 52:398-401.
    • (2014) Pharm Biol , vol.52 , pp. 398-401
    • Rojas-Silva, P.1    Graziose, R.2    Vesely, B.3
  • 28
    • 0034286955 scopus 로고    scopus 로고
    • Protective effect of black seed oil from Nigella sativa against murine cytomegalovirus infection
    • Salem ML, Hossain MS. (2000). Protective effect of black seed oil from Nigella sativa against murine cytomegalovirus infection. Int J Immunopharmacol 22:729-40.
    • (2000) Int J Immunopharmacol , vol.22 , pp. 729-740
    • Salem, M.L.1    Hossain, M.S.2
  • 29
    • 41449118351 scopus 로고    scopus 로고
    • Leishmaniasis treatment-A challenge that remains: A review
    • Santos DO, Coutinho CE, Madeira MF, et al. (2004). Leishmaniasis treatment-A challenge that remains: A review. Parasitol Res 103: 1-10.
    • (2004) Parasitol Res , vol.103 , pp. 1-10
    • Santos, D.O.1    Coutinho, C.E.2    Madeira, M.F.3
  • 30
  • 31
    • 82155197191 scopus 로고    scopus 로고
    • Leishmanicidal activity of the Agaricus blazei Murill in different Leishmania species
    • Valadares DG, Duarte MC, Oliveira JS, et al. (2011). Leishmanicidal activity of the Agaricus blazei Murill in different Leishmania species. Parasitol Int 60:357-63.
    • (2011) Parasitol Int , vol.60 , pp. 357-363
    • Valadares, D.G.1    Duarte, M.C.2    Oliveira, J.S.3
  • 32
    • 0034777905 scopus 로고    scopus 로고
    • Antiprotozoal activities of Colombian plants
    • Weninger B, Robledo S, Arango GJ, et al. (2001). Antiprotozoal activities of Colombian plants. J Ethnopharmacol 78:193-200.
    • (2001) J Ethnopharmacol , vol.78 , pp. 193-200
    • Weninger, B.1    Robledo, S.2    Arango, G.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.