Screening of promising chemotherapeutic candidates from plants against human adult T-cell leukemia/lymphoma (IV): Phenanthroindolizidine alkaloids from Tylophora tanakae leaves

Journal of Natural Medicines

Volumn 69, Issue 3, 2015, Pages 397-401

  Nakano, Daisuke ^a   Ishitsuka, Kenji ^a   Ikeda, Mizuki ^a   Tsuchihashi, Ryota ^a   Okawa, Masafumi ^a   Okabe, Hikaru ^a   Tamura, Kazuo ^a   Kinjo, Junei ^a  

^a FUKUOKA UNIVERSITY   (Japan)

Author keywords

Adult T cell leukemia lymphoma; Phenanthroindolizidine alkaloids; Screening; Tylophora tanakae

Indexed keywords

14BETA HYDROXYTYLOPHORINE N OXIDE; 3 DEMETHYL 14ALPHA HYDROXYISOTYLOCREBRINE N OXIDE; 3 DEMETHYL 14BETA HYDROXYISOTYLOCREBRINE; 7 DEMETHYLTYLOPHORINE; ALKALOID DERIVATIVE; ANTINEOPLASTIC AGENT; ASCLEPIAS CURASSAVICA EXTRACT; CYNANCHUM CAUDATUM EXTRACT; DOXORUBICIN; ISOTYLOCREBRINE; ISOTYLOCREBRINE N OXIDE; MARSDENIA CUNDURANGO EXTRACT; MARSDENIA TOMENTOSA EXTRACT; METAPLEXIS JAPONICA EXTRACT; PERIPLOCA EXTRACT; PHENANTHROINDOLIZIDINE ALKALOID; PLANT EXTRACT; TYLOPHORA OVATA EXTRACT; TYLOPHORA OVATA VAR. BROWNII EXTRACT; TYLOPHORA TANAKAE EXTRACT; TYLOPHORINE; TYLOPHORINE N OXIDE; TYLOPHORININE N OXIDE; UNCLASSIFIED DRUG; ALKALOID; INDOLIZINE DERIVATIVE; PHENANTHROINDOLIZIDINE; PHENANTHROLINE DERIVATIVE;

ANTIPROLIFERATIVE ACTIVITY; APOCYNACEAE; ARTICLE; ASCLEPIAS CURASSAVICA; CONTROLLED STUDY; CYNANCHUM CAUDATUM; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SCREENING; HUMAN; HUMAN CELL; HUMAN T CELL LEUKEMIA VIRUS INFECTION; HUMAN T-LYMPHOTROPIC VIRUS 1; MARSDENIA CUNDURANGO; MARSDENIA TOMENTOSA; METAPLEXIS JAPONICA; NONHUMAN; PERIPLOCA; PLANT LEAF; STRUCTURE ACTIVITY RELATION; T CELL LEUKEMIA; T LYMPHOCYTE; TOXICITY TESTING; TYLOPHORA; TYLOPHORA OVATA; TYLOPHORA OVATA VAR. BROWNII; TYLOPHORA TANAKAE; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; HTLV-I INFECTIONS; ISOLATION AND PURIFICATION; LEUKEMIA-LYMPHOMA, ADULT T-CELL; TUMOR CELL LINE; VIROLOGY;

ALKALOIDS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; HTLV-I INFECTIONS; HUMANS; INDOLIZINES; LEUKEMIA-LYMPHOMA, ADULT T-CELL; PHENANTHROLINES; PLANT LEAVES; STRUCTURE-ACTIVITY RELATIONSHIP; T-LYMPHOCYTES; TYLOPHORA;

EID: 84930767152     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-015-0906-8     Document Type: Article

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