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Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 19, 2011, Pages 5978-5981

Synthesis of phenanthroindolizidine alkaloids and evaluation of their antitumor activities and toxicities

(6) Ikeda, Takashi a Yaegashi, Takashi a Matsuzaki, Takeshi a Yamazaki, Ryuta a Hashimoto, Syusuke a Sawada, Seigo a

a YAKULT CENTRAL INSTITUTE FOR MICROBIOLOGICAL RESEARCH (Japan)

Author keywords

Antitumor activity; Phenanthroindolizidine alkaloid; Toxicity

Indexed keywords

ALKALOID DERIVATIVE; ANTINEOPLASTIC AGENT; IRINOTECAN; PHENANTHROINDOLIZIDINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG EFFICACY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN;

ALKALOIDS; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HT29 CELLS; HUMANS; HYDROXIDES; INDOLIZINES; MALE; MICE; MOLECULAR STRUCTURE; PHENANTHROLINES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 80052598174 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.07.120 Document Type: Article

Times cited : (19)

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