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Volumn 50, Issue 6, 2015, Pages 645-656

Overexpression of NRG1 promotes progression of gastric cancer by regulating the self-renewal of cancer stem cells

Author keywords

Cancer associated fibroblasts; Gastric cancer stem cells; NRG1

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; NEU DIFFERENTIATION FACTOR; NRG1 PROTEIN, HUMAN;

EID: 84930764578     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-014-1008-1     Document Type: Article
Times cited : (40)

References (33)
  • 1
    • 9244241576 scopus 로고    scopus 로고
    • Identification of human brain tumour initiating cells
    • COI: 1:CAS:528:DC%2BD2cXpvVCjtbY%3D, PID: 15549107
    • Singh SK, Hawkins C, Clarke ID, et al. Identification of human brain tumour initiating cells. Nature. 2004;432:396–401.
    • (2004) Nature , vol.432 , pp. 396-401
    • Singh, S.K.1    Hawkins, C.2    Clarke, I.D.3
  • 3
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
    • PID: 17122772
    • O’Brien CA, Pollett A, Gallinger S, Dick JE. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature. 2007;445:106–10.
    • (2007) Nature , vol.445 , pp. 106-110
    • O’Brien, C.A.1    Pollett, A.2    Gallinger, S.3    Dick, J.E.4
  • 4
    • 33846095137 scopus 로고    scopus 로고
    • Identification and expansion of human colon-cancer-initiating cells
    • COI: 1:CAS:528:DC%2BD2sXhsFOmug%3D%3D, PID: 17122771
    • Ricci-Vitiani L, Lombardi DG, Pilozzi E, et al. Identification and expansion of human colon-cancer-initiating cells. Nature. 2007;445:111–5.
    • (2007) Nature , vol.445 , pp. 111-115
    • Ricci-Vitiani, L.1    Lombardi, D.G.2    Pilozzi, E.3
  • 5
    • 80054772926 scopus 로고    scopus 로고
    • Cancer spheres from gastric cancer patients provide an ideal model system for cancer stem cell research
    • COI: 1:CAS:528:DC%2BC3MXhtlShtb%2FI, PID: 21448722
    • Han ME, Jeon TY, Hwang SH, et al. Cancer spheres from gastric cancer patients provide an ideal model system for cancer stem cell research. Cell Mol Life Sci. 2011;68:3589–605.
    • (2011) Cell Mol Life Sci , vol.68 , pp. 3589-3605
    • Han, M.E.1    Jeon, T.Y.2    Hwang, S.H.3
  • 6
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • COI: 1:CAS:528:DC%2BD2MXhtVOrurbJ, PID: 16153702
    • Boyer LA, Lee TI, Cole MF, et al. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell. 2005;122:947–56.
    • (2005) Cell , vol.122 , pp. 947-956
    • Boyer, L.A.1    Lee, T.I.2    Cole, M.F.3
  • 7
    • 70350220586 scopus 로고    scopus 로고
    • Mechanisms of stem cell self-renewal
    • COI: 1:CAS:528:DC%2BD1MXhsVKisbvJ, PID: 19575646
    • He S, Nakada D, Morrison SJ. Mechanisms of stem cell self-renewal. Annu Rev Cell Dev Biol. 2009;25:377–406.
    • (2009) Annu Rev Cell Dev Biol , vol.25 , pp. 377-406
    • He, S.1    Nakada, D.2    Morrison, S.J.3
  • 8
    • 80053030114 scopus 로고    scopus 로고
    • The cancer stem cell niche–there goes the neighborhood?
    • COI: 1:CAS:528:DC%2BC3MXhtF2jt77M, PID: 21792897
    • Cabarcas SM, Mathews LA, Farrar WL. The cancer stem cell niche–there goes the neighborhood? Int J Cancer. 2011;129:2315–27.
    • (2011) Int J Cancer , vol.129 , pp. 2315-2327
    • Cabarcas, S.M.1    Mathews, L.A.2    Farrar, W.L.3
  • 10
    • 77951975325 scopus 로고    scopus 로고
    • Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
    • COI: 1:CAS:528:DC%2BC3cXlsFGgsrw%3D, PID: 20418870
    • Vermeulen L, De Sousa EMF, van der Heijden M, et al. Wnt activity defines colon cancer stem cells and is regulated by the microenvironment. Nat Cell Biol. 2010;12:468–76.
    • (2010) Nat Cell Biol , vol.12 , pp. 468-476
    • Vermeulen, L.1    De Sousa, E.M.F.2    van der Heijden, M.3
  • 11
    • 34548611498 scopus 로고    scopus 로고
    • Role of heregulin in human cancer
    • COI: 1:CAS:528:DC%2BD2sXhtF2qtLnN, PID: 17530167
    • Breuleux M. Role of heregulin in human cancer. Cell Mol Life Sci. 2007;64:2358–77.
    • (2007) Cell Mol Life Sci , vol.64 , pp. 2358-2377
    • Breuleux, M.1
  • 12
    • 19944404432 scopus 로고    scopus 로고
    • Roles for neuregulins in human cancer
    • COI: 1:CAS:528:DC%2BD2MXnvVWrsb0%3D, PID: 16035612
    • Stove C, Bracke M. Roles for neuregulins in human cancer. Clin Exp Metastasis. 2004;21:665–84.
    • (2004) Clin Exp Metastasis , vol.21 , pp. 665-684
    • Stove, C.1    Bracke, M.2
  • 13
    • 76949108807 scopus 로고    scopus 로고
    • Overexpression of stathmin1 in the diffuse type of gastric cancer and its roles in proliferation and migration of gastric cancer cells
    • COI: 1:CAS:528:DC%2BC3cXitVWgt7Y%3D, PID: 20087351
    • Jeon TY, Han ME, Lee YW, et al. Overexpression of stathmin1 in the diffuse type of gastric cancer and its roles in proliferation and migration of gastric cancer cells. Br J Cancer. 2010;102:710–8.
    • (2010) Br J Cancer , vol.102 , pp. 710-718
    • Jeon, T.Y.1    Han, M.E.2    Lee, Y.W.3
  • 14
    • 84875748656 scopus 로고    scopus 로고
    • Clinical significance of intratumoral HER2 heterogeneity in gastric cancer
    • COI: 1:CAS:528:DC%2BC38Xhs1KqsrzJ, PID: 23146959
    • Lee HE, Park KU, Yoo SB, et al. Clinical significance of intratumoral HER2 heterogeneity in gastric cancer. Eur J Cancer. 2013;49:1448–57.
    • (2013) Eur J Cancer , vol.49 , pp. 1448-1457
    • Lee, H.E.1    Park, K.U.2    Yoo, S.B.3
  • 15
    • 79952528125 scopus 로고    scopus 로고
    • CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth
    • COI: 1:CAS:528:DC%2BC3MXjtFKisrY%3D, PID: 21397861
    • Ishimoto T, Nagano O, Yae T, et al. CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth. Cancer Cell. 2011;19:387–400.
    • (2011) Cancer Cell , vol.19 , pp. 387-400
    • Ishimoto, T.1    Nagano, O.2    Yae, T.3
  • 16
    • 84860163816 scopus 로고    scopus 로고
    • ErbB receptor tyrosine kinase/NF-kappaB signaling controls mammosphere formation in human breast cancer
    • COI: 1:CAS:528:DC%2BC38Xmslyjtbk%3D, PID: 22492965
    • Hinohara K, Kobayashi S, Kanauchi H, et al. ErbB receptor tyrosine kinase/NF-kappaB signaling controls mammosphere formation in human breast cancer. Proc Natl Acad Sci U S A. 2012;109:6584–9.
    • (2012) Proc Natl Acad Sci U S A. , vol.109 , pp. 6584-6589
    • Hinohara, K.1    Kobayashi, S.2    Kanauchi, H.3
  • 17
    • 84857601265 scopus 로고    scopus 로고
    • Pathobiological implications of the expression of EGFR, pAkt, NF-kappaB and MIC-1 in prostate cancer stem cells and their progenies
    • COI: 1:CAS:528:DC%2BC38XjsVyjurY%3D, PID: 22384099
    • Mimeault M, Johansson SL, Batra SK. Pathobiological implications of the expression of EGFR, pAkt, NF-kappaB and MIC-1 in prostate cancer stem cells and their progenies. PLoS ONE. 2012;7:e31919.
    • (2012) PLoS ONE , vol.7 , pp. e31919
    • Mimeault, M.1    Johansson, S.L.2    Batra, S.K.3
  • 18
    • 80051800349 scopus 로고    scopus 로고
    • Blockade of the NFkappaB pathway drives differentiating glioblastoma-initiating cells into senescence both in vitro and in vivo
    • COI: 1:CAS:528:DC%2BC3MXjsF2htL8%3D, PID: 21423202
    • Nogueira L, Ruiz-Ontanon P, Vazquez-Barquero A, et al. Blockade of the NFkappaB pathway drives differentiating glioblastoma-initiating cells into senescence both in vitro and in vivo. Oncogene. 2011;30:3537–48.
    • (2011) Oncogene , vol.30 , pp. 3537-3548
    • Nogueira, L.1    Ruiz-Ontanon, P.2    Vazquez-Barquero, A.3
  • 19
    • 84877038661 scopus 로고    scopus 로고
    • The expression and localization of neuregulin-1 (Nrg1) in the gastrointestinal system of the rhesus monkey
    • COI: 1:CAS:528:DC%2BC3sXhtl2lurvN, PID: 23690216
    • Zhao WJ. The expression and localization of neuregulin-1 (Nrg1) in the gastrointestinal system of the rhesus monkey. Folia Histochem Cytobiol. 2013;51:38–44.
    • (2013) Folia Histochem Cytobiol , vol.51 , pp. 38-44
    • Zhao, W.J.1
  • 20
    • 27744586900 scopus 로고    scopus 로고
    • NRG1 gene rearrangements in clinical breast cancer: identification of an adjacent novel amplicon associated with poor prognosis
    • COI: 1:CAS:528:DC%2BD2MXhtF2ns7zO, PID: 16027731
    • Prentice LM, Shadeo A, Lestou VS, et al. NRG1 gene rearrangements in clinical breast cancer: identification of an adjacent novel amplicon associated with poor prognosis. Oncogene. 2005;24:7281–9.
    • (2005) Oncogene , vol.24 , pp. 7281-7289
    • Prentice, L.M.1    Shadeo, A.2    Lestou, V.S.3
  • 21
    • 84886928384 scopus 로고    scopus 로고
    • Gastric stem cells and gastric cancer stem cells
    • PID: 23560232
    • Han ME, Oh SO. Gastric stem cells and gastric cancer stem cells. Anat Cell Biol. 2013;46:8–18.
    • (2013) Anat Cell Biol. , vol.46 , pp. 8-18
    • Han, M.E.1    Oh, S.O.2
  • 22
    • 77954027650 scopus 로고    scopus 로고
    • Dysregulation of cellular signaling in gastric cancer
    • COI: 1:CAS:528:DC%2BC3cXotVWltbY%3D, PID: 20488613
    • Wu WK, Cho CH, Lee CW, et al. Dysregulation of cellular signaling in gastric cancer. Cancer Lett. 2010;295:144–53.
    • (2010) Cancer Lett , vol.295 , pp. 144-153
    • Wu, W.K.1    Cho, C.H.2    Lee, C.W.3
  • 23
    • 57249104900 scopus 로고    scopus 로고
    • NF-kappaB activates transcription of the RNA-binding factor HuR, via PI3 K-AKT signaling, to promote gastric tumorigenesis
    • Kang MJ, Ryu BK, Lee MG, et al. NF-kappaB activates transcription of the RNA-binding factor HuR, via PI3 K-AKT signaling, to promote gastric tumorigenesis. Gastroenterology. 2008;135:2030-42, 42 e1–3.
    • Gastroenterology. 2008;135:2030-42 , vol.42 , pp. e1-e3
    • Kang, M.J.1    Ryu, B.K.2    Lee, M.G.3
  • 24
    • 9944252386 scopus 로고    scopus 로고
    • Rho/Rhotekin-mediated NF-kappaB activation confers resistance to apoptosis
    • COI: 1:CAS:528:DC%2BD2cXpvV2rtLs%3D, PID: 15480428
    • Liu CA, Wang MJ, Chi CW, et al. Rho/Rhotekin-mediated NF-kappaB activation confers resistance to apoptosis. Oncogene. 2004;23:8731–42.
    • (2004) Oncogene , vol.23 , pp. 8731-8742
    • Liu, C.A.1    Wang, M.J.2    Chi, C.W.3
  • 25
    • 80053531658 scopus 로고    scopus 로고
    • Regulation of cancer stem cells by cytokine networks: attacking cancer’s inflammatory roots
    • COI: 1:CAS:528:DC%2BC3MXht1Ggs7jP, PID: 21685479
    • Korkaya H, Liu S, Wicha MS. Regulation of cancer stem cells by cytokine networks: attacking cancer’s inflammatory roots. Clin Cancer Res. 2011;17:6125–9.
    • (2011) Clin Cancer Res , vol.17 , pp. 6125-6129
    • Korkaya, H.1    Liu, S.2    Wicha, M.S.3
  • 27
    • 0032744698 scopus 로고    scopus 로고
    • Expression of heregulin alpha, erbB2, and erbB3 and their influences on proliferation of gastric epithelial cells
    • COI: 1:CAS:528:DyaK1MXnsVCqtr4%3D, PID: 10535875
    • Noguchi H, Sakamoto C, Wada K, et al. Expression of heregulin alpha, erbB2, and erbB3 and their influences on proliferation of gastric epithelial cells. Gastroenterology. 1999;117:1119–27.
    • (1999) Gastroenterology , vol.117 , pp. 1119-1127
    • Noguchi, H.1    Sakamoto, C.2    Wada, K.3
  • 28
    • 33646889748 scopus 로고    scopus 로고
    • Heregulin-alpha and heregulin-beta expression is linked to a COX-2-PGE2 pathway in human gastric fibroblasts
    • COI: 1:CAS:528:DC%2BD28XlvVeisb4%3D, PID: 16357062
    • Nagata K, Wada K, Tatsuguchi A, et al. Heregulin-alpha and heregulin-beta expression is linked to a COX-2-PGE2 pathway in human gastric fibroblasts. Am J Physiol Gastrointest Liver Physiol. 2006;290:G1243–51.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290 , pp. G1243-G1251
    • Nagata, K.1    Wada, K.2    Tatsuguchi, A.3
  • 29
    • 0031739613 scopus 로고    scopus 로고
    • Bershadsky AD. Morphogenetic effects of neuregulin (neu differentiation factor) in cultured epithelial cells
    • COI: 1:CAS:528:DyaK1cXnt1Gqsbk%3D, PID: 9802906
    • Chausovsky A, Tsarfaty I, Kam Z, et al. Bershadsky AD. Morphogenetic effects of neuregulin (neu differentiation factor) in cultured epithelial cells. Mol Biol Cell. 1998;9:3195–209.
    • (1998) Mol Biol Cell , vol.9 , pp. 3195-3209
    • Chausovsky, A.1    Tsarfaty, I.2    Kam, Z.3
  • 30
    • 0030876723 scopus 로고    scopus 로고
    • Clinicopathologic analysis of amphiregulin and heregulin immunostaining in breast neoplasia
    • COI: 1:STN:280:DyaK2svjtFShsg%3D%3D, PID: 9285119
    • Visscher DW, Sarkar FH, Kasunic TC, Reddy KB. Clinicopathologic analysis of amphiregulin and heregulin immunostaining in breast neoplasia. Breast Cancer Res Treat. 1997;45:75–80.
    • (1997) Breast Cancer Res Treat , vol.45 , pp. 75-80
    • Visscher, D.W.1    Sarkar, F.H.2    Kasunic, T.C.3    Reddy, K.B.4
  • 31
    • 84874666281 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling
    • PID: 22535374
    • De Boeck A, Pauwels P, Hensen K, et al. Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling. Gut. 2013;62:550–60.
    • (2013) Gut , vol.62 , pp. 550-560
    • De Boeck, A.1    Pauwels, P.2    Hensen, K.3
  • 32
    • 80051578430 scopus 로고    scopus 로고
    • Neuregulin-1-mediated autocrine signaling underlies sensitivity to HER2 kinase inhibitors in a subset of human cancers
    • COI: 1:CAS:528:DC%2BC3MXhtVWrt7nK, PID: 21840482
    • Wilson TR, Lee DY, Berry L, Shames DS, Settleman J. Neuregulin-1-mediated autocrine signaling underlies sensitivity to HER2 kinase inhibitors in a subset of human cancers. Cancer Cell. 2011;20:158–72.
    • (2011) Cancer Cell , vol.20 , pp. 158-172
    • Wilson, T.R.1    Lee, D.Y.2    Berry, L.3    Shames, D.S.4    Settleman, J.5
  • 33
    • 0032504036 scopus 로고    scopus 로고
    • Expression of mRNA for heregulin and its receptor, ErbB-3 and ErbB-4, in human upper gastrointestinal mucosa
    • COI: 1:CAS:528:DyaK1cXkvVOlsbw%3D, PID: 9718081
    • Kataoka H, Joh T, Kasugai K, et al. Expression of mRNA for heregulin and its receptor, ErbB-3 and ErbB-4, in human upper gastrointestinal mucosa. Life Sci. 1998;63:553–64.
    • (1998) Life Sci , vol.63 , pp. 553-564
    • Kataoka, H.1    Joh, T.2    Kasugai, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.